Researchers from the University of Leicester used a new method to extract information from 500 million-year-old fossils, revealing that some early vertebrates may have been more complex than thought. The study found that decomposition altered characteristic anatomical features, providing clues for interpreting ancient fossils.
Researchers have developed a new technique to restore lost bone and gum tissue following periodontal disease, using layers of cells such as stem cells and gingival fibroblasts. The method has been shown to be successful in laboratory studies and has potential applications in other fields like skin grafts.
Researchers found five genome regions that increase the risk of developing an SLE-like autoimmune disorder in dogs. The study identified strong risk factors that may double the risk of human SLE, and could provide new avenues for studying the disease.
Patients who underwent peripheral blood stem cell transplantation (PBSC) had similar overall survival rates as those given bone marrow transplants, with no significant differences in mortality or late effects. However, subgroup analyses revealed improved leukaemia-free survival and overall survival for patients with acute leukaemias
Neurobiologists at the University of Maryland discovered that the brain's auditory cortex is more complex and chaotic than previously thought, with neighboring neurons creating different outputs. This disorder could indicate that the brain is far more adaptable than previously thought.
Researchers identified five loci associated with a canine systemic lupus erythematosus-related disease complex in Nova Scotia duck tolling retrievers. This study suggests that dogs can serve as an excellent model for identifying pathways involved in human complex diseases, particularly autoimmune disorders.
Researchers created AraNet, a network that connects over 19,600 plant genes based on physical neighborhood and co-expression patterns. The network accurately predicted the functions of three uncharacterized genes in Arabidopsis thaliana, demonstrating its potential to revolutionize fundamental plant biology and agricultural research.
Researchers have grown a crystal that reveals the structure of integrase, an enzyme found in HIV, and how it interacts with antiretroviral drugs. This breakthrough could lead to improved treatments for HIV by understanding how existing drugs work and how to improve them.
Scientists have discovered a mechanism by which yeast cells transport damaged proteins to mother cells using conveyor-like structures called actin cables. This process ensures that newly formed daughter cells are born without age-related damage, paving the way for potential treatments of age-related diseases.
Research on patient access schemes found that refunds were not always passed on to primary care trusts, leading to financial losses. The study also identified the need for flexibility in processing claims and standardized templates to streamline administration.
Pneumococcal disease is a leading vaccine-preventable killer of children under age five, causing life-threatening infections. Dr. Thomas Cherian's work has helped advance medical science and inform policy to overcome obstacles in awareness, financing, and vaccine access.