Researchers have developed an intracellular, sustained-release drug delivery system using nanoparticles called dendrimers, targeting neuroinflammation in the retina. The treatment protects vision by preventing injury to photoreceptors and reduces neuroinflammation, providing potential relief for millions of patients worldwide.
A new study suggests that small modular reactors (SMRs) could play a significant role in the future of US nuclear power generation. The report concludes that SMRs would be highly advantageous for various sectors in the US, stimulating high-valued job growth and restoring US leadership in nuclear reactor technology.
Rhode Island Hospital is conducting a 5-year study on the effectiveness of cognitive behavioral therapy (CBT) versus supportive psychotherapy for treating Body Dysmorphic Disorder (BDD). The study aims to reduce BDD symptoms and improve daily functioning.
Researchers find that internal group dynamics can lead to biased and misleading scientific findings, affecting the quality of published research. They advocate for improved collaboration practices, including clear goals and roles, to address this issue.
Researchers discovered that submerging azalea cuttings in 50°C water eliminates the deadly fungal disease. The study found that all 12 cultivars were tolerant of short submersion durations, making hot water treatment a viable alternative for disease control.
Researchers develop cost-effective technique for fabricating flexible and stretchable backplanes using semiconductor-enriched carbon nanotube solutions. The technology enables the creation of artificial electronic skin capable of detecting and responding to touch.
Research on low-dose X-ray irradiation reveals significant reduction in aerobic bacteria and mold/yeast populations, while maintaining sugar levels in asparagus. The study found that X-ray treatment can enhance consumer safety by decreasing the number of viable microorganisms.
Researchers at the Wyss Institute have developed a new material called Shrilk that replicates the exceptional strength and versatility of insect cuticle. With its unique mechanical and chemical properties, Shrilk could be used to replace plastics in consumer products, suture wounds, and serve as scaffolding for tissue regeneration.
Researchers created a record-breaking gas mixture of Lithium 6 and Potassium 40 using an ultra-freeze trap, increasing the number of atoms under study to a few billion. This breakthrough will aid in simulating subatomic-scale phenomena and understanding quantum mechanical effects in neutron stars.
A picture book portrays the life cycle and challenges of a threatened frog species in Arizona, sparking enthusiasm for conservation among children. The book, written by an ASU microbiologist, aims to educate kids about biology, ecology, and overcoming obstacles, while promoting conservation efforts.
A new study in Journal of Consumer Research found that online brand comments impact consumer attitudes differently depending on the tone and number of comments. Promotion-focused individuals react to gain-related information, while prevention-focused ones respond to loss-related information.
Researchers from the California Institute of Technology and international partners have achieved a new world record for data transfer at a combined rate of 186 gigabits per second, equivalent to moving two million gigabytes per day. This milestone is crucial for dealing with massive amounts of data coming from the Large Hadron Collider.
Researchers at Tufts University have discovered a novel mechanism regulating stress response in the brain, involving neurosteroids and specific receptors. Blocking these receptors may lead to new approaches for managing stress-related disorders such as depression, epilepsy, and obesity.
A new test developed by QUT PhD student Helen McCosker can predict the likelihood of breast cancer growth, dormancy, or spread to other organs. The test analyzes tissue surrounding cancer cells and offers personalized treatment plans for patients.
A new prognostic model developed by researchers at the University of Texas M. D. Anderson Cancer Center has identified three risk groups for patients with treatment-related myelodysplastic syndrome, each with different survival prospects. The model incorporates multiple factors, including age, cytogenetics, and serum hemoglobin levels,...
A new chemical technique has been developed to deposit a non-crystalline form of silicon into ultra-thin pores of optical fibers. This allows for the creation of more-efficient and flexible optical fibers with hydrogenated amorphous silicon, ideal for applications such as solar cells and telecommunications.
Researchers have developed a vaccine that successfully attacks breast cancer in mice, with implications for treating ovarian, colorectal and pancreatic cancer. The vaccine targets MUC1, a protein found on over 90% of human breast and pancreatic cancer cases.
Researchers at Johns Hopkins University have developed a hydrogel treatment that promotes new blood vessel formation and tissue regeneration, yielding scar-free skin in mouse tissue tests. The treatment has the potential to greatly improve healing for injured soldiers, home fire victims, and others with third-degree burns.
Scientists at NASA's Goddard Space Flight Center are developing a comet harpoon to rapidly acquire samples from specific locations on rotating comets. The harpoon uses a
The American Cancer Society has revised its guideline formation process to prioritize transparency, consistency, and scientific rigor. The new process involves a systematic evidence review, independent writing group, and clear articulation of benefits, limitations, and harms associated with cancer screening tests.
A team of researchers at RUB discovered how the human nose distinguishes between similar smells by analyzing the 3D structure of olfactory receptors and hydrogen bridge patterns. They found a specific pattern of chemical bonds that account for the specificity of olfactory sensors.
A large trial in Ethiopia found that self-epilation using clean forceps is an acceptable alternative to surgery for treating minor trachomatous trichiasis. This approach preserves vision and offers logistical advantages over traditional surgical methods, making it a promising solution for low-resource countries.
A new study published in HortScience finds that the Ridge-Furrow-Ridge Rainwater Harvesting (RFRRH) system with mulches increases soil water content, crop yield, and reduces labor costs. The system also manages weed control without irrigation.
A unique Swedish study of 691 widower men showed that finding a new partner within four to five years of losing their wife significantly reduced the risk of developing depression, anxiety, and sleep disorders. In contrast, those who remained single faced higher risks and were more likely to use sleeping pills and antidepressants.
Researchers from the University of Bristol have discovered a chemical compound in the brain that can weaken synaptic connections between neurons. This finding may provide a potential explanation for memory loss associated with Alzheimer's disease.
A study by Dr Matt Barnes found that two-thirds of workers work at unusual times, limiting their leisure time and social interactions. Older people, particularly those living alone, experience poor social relations and social exclusion, with many spending hours alone each day.
A large study group of Kentucky women found that only 30% were receiving warfarin for atrial fibrillation. The study suggests warfarin anticoagulation treatment is underutilized in this population, but not due to economic or educational disparities.
A recent study found that nostalgia increases both tangible donations and global intentions for charity appeals, suggesting it can foster empathy and encourage charitable behavior. The researchers used five studies to investigate the relationship between nostalgia and charitable giving, with positive results.
Researchers have developed technology using microneedles to detect real-time chemical changes in the body, allowing for continuous monitoring. This innovation could enable personalized medical care and unlock new research opportunities.
Researchers from the University of Guam and Japan are collaborating on a new method for controlling sweet potato weevil pests using Integrated Pest Management (IPM) techniques. The team has successfully developed traps containing fungal spores, which have shown high effectiveness in reducing weevil populations.
A team of scientists at Cold Spring Harbor Laboratory discovered that hydrogen sulfide regulates a signaling pathway implicated in biological malfunctions. H2S modifies an enzyme called PTP1B, preventing it from inactivating PERK, a sensor of unfolded proteins and a critical regulator of cell response to ER stress.
The Radiation Assessment Detector (RAD) is measuring radiation levels on NASA's next rover mission to Mars. RAD characterizes the radiation environment astronauts would experience during a future human mission to Mars.
Researchers at Wayne State University, Mayo Clinic and Johns Hopkins have developed a targeted drug delivery system using nanoparticles called dendrimers. This system reduced neuroinflammation in the retina and protected vision by preventing injury to photoreceptors.
Consumers tend to favor brands that appear on their own Facebook pages, even if they don't consciously notice it. This phenomenon, known as implicit self-referencing, is linked to high self-esteem and positive associations with one's online identity.
Researchers have discovered a protein family known as SWEET that plays a crucial role in transporting sucrose from leaves to other parts of the plant. The discovery could lead to increased crop yields and improved protection against pests, potentially even shedding light on human diseases like diabetes and obesity.
Researchers from the University of Pennsylvania have successfully reprogrammed astrocytes into dopamine-producing neurons, a crucial step towards treating Parkinson's disease. The study demonstrates conversion efficiency of up to 18%, paving the way for novel reprogramming strategies to treat Parkinson's disease.
A recent study found that over 1 in 50 babies are born with a birth defect, significantly more common than previously estimated. The report highlights the need for improved regional monitoring to identify causes and reduce occurrences of anomalies.
Researchers will use a three-year, $1.38 million grant to study presolar grains in a sample of the Murchison meteorite. They aim to extract exceptionally large grains that came from supernovae, allowing them to make more comprehensive measurements and understand how elements were forged.
Researchers have discovered a molecular pathway that can help reduce cardiac damage caused by an enlarged heart, a common result of hypertension or a heart attack. The pathway, activated by stretch of adult cardiac cells, promotes the release of VEGF, which protects cardiac function and keeps cells alive.
Smokers who quit successfully experience noticeable improvements in quality of life, including higher scores on overall well-being and positive emotions. After three years, quitters also report fewer stressors and increased satisfaction with their lives.
A new approach using an HIV drug has significantly reduced the incidence of graft-versus-host disease (GvHD) in blood cancer patients after allogeneic stem cell transplantation. Maraviroc dramatically reduced GvHD in organs such as the gut and liver without compromising the immune system.
Adding biochar to glacial soils reduces carbon dioxide and nitrous oxide emissions. Ethylene production is also stimulated by biochar, potentially influencing plant growth.
Previous research on stillbirth has identified strong associations between reproductive factors, health conditions, and socio-demographic characteristics. The study found that these factors significantly increase the risk of stillbirth, highlighting the importance of early prenatal care and monitoring for women with known risk factors.
Researchers found that buttercup flowers' bright yellow reflection is due to their unique petal structure, which doubles the gloss through two flat surfaces and an air gap. The study provides insight into how flowers attract pollinators like bees.
A study by UC Irvine researchers found that CKD causes depletion of adhesive proteins in the intestines, leading to systemic inflammation and cardiovascular complications. The findings could lead to novel treatments to curb this inflammation and its adverse consequences.
A study found that consumers expect communal principles in churches and pharmaceutical companies, but become outraged when they prioritize commercial interests. Organizations can communicate with consumers by framing their motives as part of their community's shared values.
A new study found that both pre-pregnant weight and weight gain during pregnancy are important predictors of babies' birthweight. Women with higher education levels had the highest offspring birthweight, highlighting the importance of a healthy weight before conception and moderate weight gain during pregnancy.
A new study reveals altered insulin signaling in the pancreas of Type 2 diabetics, resulting in a decrease in beta cell production and quality. The distorted signals disrupt the replication process of beta cells, leading to a major defect in insulin secretion.
A study found that high tau protein levels in fluid bathing the brain are linked to poor recovery after head trauma. Patients with higher initial tau levels had worse outcomes six to 12 months later.
A new study found that individuals with mood and anxiety disorders are more likely to abuse opioids. Non-medical prescription opioid use was associated with an increased risk of developing any mood disorder, major depressive disorder, bipolar disorder, and all anxiety disorders. Early identification and treatment of mood and anxiety di...
The REMOVAL study aims to test whether metformin can prevent or reduce the risk of cardiovascular complications in people with type 1 diabetes. The five-year trial will follow 500 patients and examine the effects of metformin on blood glucose control, treatment satisfaction, and other complications.
Researchers are using mini wind turbines and advanced flow measurements to understand the impact of hilly terrain on wind turbine performance. Preliminary results show that turbines on hilly terrain experience higher wind loads and recover power potential more rapidly than those on flat ground.
Parkinson's disease patients exhibit increased arm swing asymmetry and reduced coordination, which can be easily detected early with inexpensive accelerometers. This method may enhance early diagnosis and treatment opportunities, and researchers plan to further investigate its effectiveness.
A new substance, F-ara-Edu, labels DNA with little to no impact on genome function, allowing for the visualization of DNA synthesis in vivo. This approach enables the identification of virus infection and cancerous growth sites due to abundant DNA replication in these tissues.
The collaboration aims to build on Professor Susann Schweiger's discovery of the mechanism controlling disease-causing protein production. The project seeks to prevent toxic protein buildup in the brain and potentially provide a treatment for Huntington's Disease.
Researchers at the Trudeau Institute have discovered a new properties of a potential vaccine adjuvant that suggests it could be useful for enhancing protection against a number of different infections. The discovery provides a promising lead for developing a new class of vaccines.
Researchers found that the loss of elephant bones at Gesher Benot Ya'aqov site may have imposed significant nutritional stress on Homo erectus. This led to a shift towards hunting smaller prey, which is evident in the physical appearance of modern humans and suggests their emergence in the Middle East 400,000 years ago.
Mothers working part-time jobs tend to have fewer symptoms of depression and better overall health than those who stay at home. They also show no significant differences in parenting involvement or family life support compared to full-time working mothers.
Researchers identified a high-risk subgroup among older AML patients with mutated ASXL1 gene, showing significantly shorter survival and lower complete remission rates. The study's findings could lead to more effective targeted therapies for these patients.
Raising seedlings with blue light increases crop yield and quality by boosting phenolic compounds. Studies found that blue light-treated seedlings had higher leaf areas, shoot fresh weight, and antioxidant activity compared to those grown under red or white fluorescent light.