A study by Columbia Business School researchers demonstrates 'complicating choice' – the process where decision-makers increase effort for unimportant attributes. This phenomenon is driven by the 'effort compatibility principle', which aims to match expected effort with perceived effort.
A multi-institutional study published in Nature reveals the genetic overview of ovarian cancer, showing mutations in one gene and frequent structural changes that contribute to its development. The findings could lead to better treatments for this aggressive form of cancer.
A $1 million University of Nevada, Reno project is providing a catalogue of favorable structural elements and models for geothermal systems to enhance exploration methodologies and reduce the risk of drilling nonproductive wells. The research aims to identify potential geothermal sites in the Great Basin with 3-D imaging.
Research at the University of Strathclyde found that seabed-living fish in the Firth of Clyde have reached their highest level since 1927. Most fish caught are too small to be landed due to changes in species composition and size.
Researchers at Cleveland Clinic have identified a molecular pathway that promotes brain tumor growth in malignant glioma. The study found that existing medications block this pathway and delay tumor growth in animal models, suggesting a potential new treatment option.
Researchers have found that plasticity genes in the brain activate more easily when building on existing knowledge, making it easier to learn about familiar topics. This paradoxical effect may help explain how professionals acquire their knowledge gradually over time.
Researchers found that genetic mutations cause rare human diseases by disrupting a protein called Tectonic1, which forms a crucial collar around the base of cilia. This discovery provides new targets for diagnostics and treatments.
A study of 1,460 male and female basketball players found that lace-up ankle braces significantly reduced acute ankle injuries by more than three times. The use of braces was effective for both experienced and inexperienced athletes, suggesting a viable option for injury prevention.
A study from Rice University and Italy's Eugenio Medea Scientific Institute has shed light on the biochemical workings of atlastin, a protein linked to HSP. The research suggests that atlastin plays a crucial role in maintaining the health of long nerve cells affected by HSP.
The NOSCAR study compares NOTES cholecystectomy to conventional laparoscopic cholecystectomy, with approximately 200 patients enrolled. Covidien's funding supports the development of this minimally invasive technique, aiming to improve patient outcomes and reduce hospital stays.
A team of scientists identified the MB-V2 nerve cells as crucial for recalling associative memories in fruit flies. The study showed that these cells receive information from the mushroom body and relay it to other nerve cells, enabling memory 'read-out' and guiding behavior.
Researchers found a significant association between indoor air pollution and increased blood pressure among older women. Exposure to small-particle air pollution can cause premature death and lung disease, while cleaner fuels and stoves could cut cardiovascular risk by up to 22%.
A study found that children's personalities are linked to their chemical response to stress, with different patterns of hormone production associated with advantages and disadvantages in navigating threatening environments. Doves were more vigilant but prone to anxiety, while hawks were bolder but riskier.
Researchers at Beth Israel Deaconess Medical Center discovered that specific brain areas orchestrate competition between memories and that transcranial magnetic stimulation can preserve memory by targeting these areas. By applying TMS to the dorsolateral prefrontal cortex and primary motor cortex, both memories remained intact.
Researchers at the University of Pennsylvania School of Medicine have demonstrated direct conversion of a non-heart cell type into a heart cell by RNA transfer. This breakthrough approach, called Transcriptome Induced Phenotype Remodeling (TIPeR), offers potential for cell-based therapy for cardiovascular diseases and personalized scre...
A new study published in Arthritis & Rheumatism found that male smokers had a lower risk of undergoing total joint replacement surgery compared to non-smokers. High body mass index (BMI) and vigorous physical activity were also linked to an increased risk of arthroplasty in men, particularly those over 70 years old.
A new mathematical model predicts the location of mutations that lead to HIV-drug resistance, providing a potential solution to improve anti-HIV drug design. The study suggests that understanding these physical properties and interactions can help develop better strategies for combating the virus.
Researchers at MDC discover that a lack of laminin-332 causes tactile stimuli to be perceived as painful, leading to increased sensitivity and branching of sensory neurons. The findings provide new insights into the disease's mechanisms and potential drug targets for therapy.
The Drugs for Neglected Diseases Initiative (DNDi) has launched a new research project to develop a macrofilaricidal drug candidate, flubendazole, to treat co-infection of filarial diseases. The project aims to assess the safety profile and reformulate the drug to reduce treatment cycles from 12 years to 2-3 years.
Michigan State University researchers are reformulating a decades-old drug to combat two debilitating tropical diseases. The goal is to develop a safe and effective treatment for filarial diseases, which affect millions worldwide. With clinical trials expected to begin in about two years, the team hopes to bring hope to those affected ...
Researchers found that neurons can prefer multiple signals simultaneously and choose based on competing signals. This discovery could lead to more efficient brain implant design for treating neurological disorders.
Researchers found that vitamin D injections improved the removal of amyloid beta from the brain of mice, suggesting a potential therapeutic target for preventing Alzheimer's disease. Transporter proteins at the blood CSF barrier also play a crucial role in removing amyloid beta from the brain.
Researchers at Berkeley Lab observed structural transformations within a single copper sulfide nanocrystal, revealing dynamics influenced by defects. The study provides new insights into phase transitions and their relevance to battery performance and solar energy harvesting.