A study found that Droplet Digital PCR can accurately quantify and determine the size distribution of target DNA in a single reaction well, avoiding drawbacks of other methods. This method offers precise quantification and detailed size distribution analysis, enabling efficient library preparation for next-generation sequencing.
A Mayo Clinic study found that patients with glioblastoma who died in 2010, after the FDA approved bevacizumab, lived significantly longer than those who died in 2008. The treatment strategy involving bevacizumab prolonged survival at a population level.
A recent study by Ben-Gurion University researchers found that divers are willing to pay to improve aspects of reef biodiversity, with respondents ranking biodiversity as the most desirable value. The study's findings may help inform conservation efforts and direct the design of future marine reserves.
Research published in Annals of Internal Medicine suggests that low diastolic blood pressure may be a significant risk factor for mortality in patients with CKD. A study of over 651,000 veterans found that those with diastolic blood pressures below 70mmHg had higher mortality rates compared to those within the recommended range.
A new scoring system developed by researchers allows clinicians to predict the risk of dementia in older people with type 2 diabetes. The scores are based on six health complications, education, and age, accurately predicting patients' risk of developing dementia.
A fungal-bacterial consortium converts tough plant materials into isobutanol, producing 1.88 grams per liter of fluid, with 62% energy conversion rate. The system reduces capital investment and operating cost, making biofuel production economically viable.
A study found that decreased Aß42 and increased phosphorylated tau181 levels in spinal fluid are linked to reduced default mode network integrity. This association suggests that these biomarkers could be used to detect Alzheimer's disease pathology before symptoms appear.
Wildfires in central and northern California continue to rage, with the American wildfire affecting over 13,000 acres. The Swedes Fire has grown to 1,995 acres and is expected to be fully contained by Thursday.
A team of scientists has discovered a mechanism by which beneficial bacteria reside and thrive in the gastrointestinal tract. By understanding how these microbes colonize, they may be able to correct abnormal changes in bacterial communities linked to disorders like obesity and inflammatory bowel disease.
Typhoon Pewa strengthened into a powerful storm after passing over NASA's Aqua satellite, revealing a small eye surrounded by strong thunderstorms. The Joint Typhoon Warning Center predicts Pewa will continue to intensify as it moves northwest, passing far to the northeast of Wake Island on Aug. 21 and 22.
A study from the Université de Montréal found that the program improves parenting style and boosts children's psychological adjustment, leading to higher well-being levels. The three key dimensions of optimal parenting—structure, warmth, and autonomy support—showed significant increases.
Scientists have found that molten magma reservoirs in the crust can persist for far longer than previously thought, with some chambers sitting for hundreds of thousands of years. This new understanding has significant implications for volcanic arcs and the detection of magma pools beneath them.
Researchers used X-ray crystallography to visualize how brominated flame retardants bind to proteins like estrogens, potentially disrupting the body's natural hormones. The study sheds light on the effects of flame retardants on human health and provides insights for developing safer alternatives.
NASA has accepted its newest Tracking and Data Relay Satellite (TDRS) into the network, replenishing an aging fleet essential for space exploration. The new satellite will provide critical real-time communication support for NASA's human spaceflights, International Space Station activities, and various science missions.
Researchers have discovered that ancient Egyptian iron beads were hammered from pieces of meteorites, not iron ore. The findings indicate that metalworkers mastered the smithing of meteoritic iron over 5,000 years ago, enabling the development of iron smelting and replacing copper and bronze as primary metals.
Researchers have created a new drug-delivery strategy using a biodegradable coating that prolongs the effectiveness of an eye medication for macular degeneration. This innovation could significantly reduce the frequency of injections needed, potentially changing the standard of care from monthly to once or twice a year.
A study led by UT Southwestern Medical Center researchers found that total tumor measurements greater than 3 inches predict shorter survival times in advanced lung cancer patients. Patients with larger tumors live an average of 9.5 months, compared to 12.6 months for those with smaller tumors.
A new study on carbonado diamonds reveals the presence of a 3D connected pore network, while another paper discusses sea-level change off New Jersey and ancient Sierra Nevada faulting. Meanwhile, volcanic activity in Hawaii is examined through core-seismic-log integration.
Tropical Depression 13W formed on Aug 17 and dissipated less than a day later, with NASA capturing its final image via the MODIS instrument aboard Aqua satellite. The storm's weakened state allowed nearby Tropical Storm Trami to take over, leading to the depression's demise.
A study by an international consortium of researchers found that reducing the expression of NEET proteins significantly reduced cancer cell proliferation and tumor size. The overabundance of these proteins is linked to the progression of the disease, making them a prime target for anticancer drugs.
Researchers at Duke University Medical Center found that increased caffeine intake may reduce fatty liver in people with non-alcoholic fatty liver disease. Consuming four cups of coffee or tea a day could be beneficial in preventing and protecting against the progression of NAFLD.
New study published in Journal of Hospital Medicine outlines top recommendations for improving healthcare value, including reducing unnecessary tests and procedures. The recommendations aim to lower costs and lead to better care for patients, particularly children and adults hospitalized with respiratory illnesses.
A new study reveals that bullying in childhood can lead to serious illness, poor job prospects, and strained social relationships. Bully-victims are particularly vulnerable, facing a higher risk of mental health issues, poverty, and difficulties forming long-term friendships.
A new study published in Neurology suggests that high-altitude flying increases the risk of brain lesions. The research found that pilots had nearly four times the volume and three times the number of brain lesions as non-pilots, with lesions evenly distributed throughout the brain.
Moths hear at 80 kHz to detect bats, but this ability also leads to unnecessary sound impressions and energy waste. Researchers found that moths' eardrums are more sensitive than small insects', allowing them to survive in environments with high-frequency bat calls.
A novel study in Arthritis Care & Research examines the medical response and imaging technologies used to treat Boston Marathon bombing victims. The study found that radiology resources should be used liberally to save lives and limbs in urgent situations like the Boston Marathon bombing.
IBN's novel technique allows researchers to incorporate different cell types into separate fibers, then assemble them into complex constructs with hierarchical tissue structures. This innovation enables the creation of prevascularized tissue constructs that have successfully integrated with the host circulatory system in a mouse model.
The Rhode Island Consortium for Autism Research and Treatment (RI-CART) has received a $1.2 million grant to create a confidential registry of individuals diagnosed with autism in the state. The registry aims to improve diagnoses and treatments by connecting families with clinical experts and researchers.
A new study estimates that the global cost of flooding could increase from $6 billion to $52 billion per year, with some cities facing losses exceeding $1 trillion if inaction is taken. The top 10 most at-risk cities are in developed and developing countries, with high wealth but low protection levels.
A research letter reveals that indoor tanning is common among non-Hispanic white female high school students and adults ages 18 to 34 years, with significant age-related differences in prevalence. The study estimates that 29.3% of high school students and 24.9% of women in this age group engage in indoor tanning annually.
Researchers documented irregular brain activity within hours of a concussive injury and increased brain activity weeks later, indicating the brain may compensate for the injury. The study suggests a new approach to deciding when athletes can return to play after a concussion.
A study published in JAMA Neurology reveals that disruptions in brain networks emerge simultaneously with chemical markers of early Alzheimer's disease. The research provides an effective and less invasive way to detect early disease, potentially improving treatment outcomes.
Patients with heart failure who see a physician within a month of hospital discharge have better survival rates compared to those without follow-up care. Continuity with a familiar physician is most beneficial, reducing risk of readmission and death by 3-8%.
A US model of collaborative care for depression has been shown to improve symptoms immediately after treatment. After 12 months, 15% more patients remained improved compared to those who saw their GP alone.
A large population study of over 20,000 psychedelic users found no link between LSD and mental health problems. Instead, researchers discovered a significant association with fewer mental health issues.
Researchers at Whitehead Institute created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of prion diseases, including Creutzfeldt-Jakob disease and fatal familial insomnia.
New research by World Vision and Columbia University shows that Child Friendly Spaces can help Congolese children recover from trauma after fleeing conflict. Children who frequently attended CFS sustained their psychosocial wellbeing, while those who didn't showed significant deterioration.
A study found that copper accelerates the pathology of Alzheimer's disease by disrupting the removal of amyloid beta from the brain and stimulating its production. Copper accumulation can lead to inflammation and breakdown of the blood-brain barrier, promoting toxic protein buildup.
A study by UNH researchers found no significant benefit of post-exercise ice baths in reducing muscle soreness or improving strength after intense exercise. Despite initial skepticism, lead researcher Naomi Crystal notes that moderate use of cryotherapy may still be beneficial for elite athletes.
Scientists have discovered a vast plume of iron and micronutrients in the South Atlantic Ocean, challenging previous estimates of iron sources in the world's seas. The finding has profound implications for understanding ocean life and Earth's climate as it suggests that slow-spreading ridges may be a significant source of iron.
Professor Des Higham has received a Leverhulme Trust Senior Research Fellowship to research potential applications of social media data. He aims to identify interest groups, categorize network users based on influence and predict energy usage in individual households.
Researchers found that suitable habitats were settled first by early migrants, leading to a diverse patchwork of language groups. This process may account for global ethnolinguistic patterns.
Wayne State University has received a $200,000 National Science Foundation grant to develop an undergraduate certificate program in nanoengineering. The program aims to prepare students for flexible employment opportunities and provide them with hands-on knowledge of cutting-edge technologies.
A series of devastating wildfires has swept through Idaho, with multiple fires burning out of control due to strong winds and hot temperatures. The largest fire, the Beaver Creek Fire, has grown to over 100,000 acres and threatens nearby towns and ski resorts.
Researchers created the first risk score predicting 10-year dementia risk for type 2 diabetes patients based on medical history and electronic health records. The Diabetes-Specific Dementia Risk Score assigns a value to eight predictive factors, including microvascular disease and diabetic foot.
A study by Dr. Karen Ruebens reveals two separate Neanderthal cultures in Europe, with distinct handaxe designs and social learning mechanisms. The research provides new insights into Neanderthal regionality and cultural complexity.
Tropical Storm Unala weakened to a depression after forming in the central Pacific, with cloud top temperatures indicating strong storms with heavy rain potential. The storm's interaction with Typhoon Pewa is expected to cause further weakening and dissipation within 24 hours.
Tropical Storm Trami appears very large in infrared data from NASA's Aqua satellite, spanning over two-thirds the size of the Philippines. The massive storm is now making a U-turn in the Northwestern Pacific Ocean.
Researchers found significant regional differences in the relationship between population and air pollution, particularly in Europe and India. Nitrogen dioxide concentrations more than doubled when cities increased in population from 1 million to 10 million people.
A new MR analysis technique called vessel architectural imaging (VAI) can identify changes in brain tumor blood vessels within days of anti-angiogenesis therapy initiation. VAI has shown that 10 out of 30 patients with recurrent glioblastoma responded to the treatment, surviving six months longer than non-responders.
A genetic variant linked to a cell's internal clock has been associated with myeloma, a common type of blood cancer. The study identified four new genetic variants linked to myeloma, bringing the total number to seven.
Researchers discovered that small damsel fish grow larger 'eye' spots near their tail and reduce the size of their real eyes when threatened with predation. This allows them to distract predators and increase their chances of survival.
Researchers at Monash University create magnesium alloy with reduced corrosion rates by adding arsenic, a cathodic poison. This breakthrough could lead to widespread adoption of lightweight magnesium in transportation industries.
A long-term study of insulin pump therapy in children with type 1 diabetes found improved HbA1c control and reduced episodes of severe hypoglycaemia. Pump therapy also led to lower rates of diabetic ketoacidosis compared to injections.
Researchers at the Children's Hospital of Philadelphia developed a new approach to cancer immunotherapy by adjusting the function of immune cells. They showed that inhibiting the enzyme p300 can reduce Treg cell function and limit tumor growth in mice, offering potential for anti-tumor therapy.
Researchers at Virginia Tech have developed a wearable helmet sensor that can detect the onset of carbon monoxide poisoning in construction workers with a probability of greater than 99%. The sensor uses pulse oximetry technology to monitor blood gas saturation levels, providing early warnings to prevent potential harm.
A phase I clinical trial shows that diffuse, large B-cell lymphomas resistant to chemotherapy can be reprogrammed to respond using the drug azacitidine. Patients whose tumors do not respond to standard therapies are being treated with a combination of approaches, including high-dose chemotherapy and stem cell transplant.
In a study of gray tree frogs, females preferred calls that were longer and more frequent, which is a challenging task. The findings support the multitasking hypothesis, suggesting that high-quality males can produce multiple signals at once.
Tropical Storm Erin weakened to a tropical depression due to cooler waters and dry air in the Eastern Atlantic. Its maximum sustained winds dropped to near 35 mph, with no significant changes expected over the next couple of days.
Tropical Storm Pewa has formed in the central Pacific, according to NASA's satellite imagery. System 90C, located about 775 miles south-southwest of Kauai, Hawaii, has a medium chance (30%) of developing into a tropical cyclone within the next 48 hours.