The distraction osteogenesis technique successfully increased the length of the maxilla by an average of 6.4 millimeters in seven adolescent to young adult patients with cleft lip and palate deformities. This approach showed benefits over standard surgical methods, with significantly less bone regression after follow-up.
A new study by Thomas W. Buford et al. examines the ACE I/D gene and its impact on older adults' response to exercise. The researchers found that genetic variations can influence exercise-induced changes in physical function among mobility-limited seniors.
Research shows that even low-energy radiation can cause DNA damage, including double-strand breaks, which are often irreparable. Industry characterization of 'eye-safe' lasers at wavelengths longer than 1300nm is flawed, as these wavelengths can induce damage to DNA in the eye
Researchers found that mechanical tension is established shortly after muscle-tendon contact, providing positional information for sarcomere formation. Without tension, muscles fail to build regular myofibrils, resulting in chaotic protein distribution.
Researchers assessed 1,095 patients following acute fractures and found poor sleep independently associated with poor emotional status. Orthopaedic surgeons should monitor patient mental health and counsel patients on sleep expectations to provide highest level of care after fracture treatment.
Researchers at CAB successfully recreated Europa's crust in a laboratory experiment, revealing that high-pressure fluids could be responsible for the moon's reddish materials. The study suggests that certain characteristics of Europa's surface may be explained by a saline aqueous medium, with significant implications for life on Earth.
Researchers have developed a novel approach to treating CLL by disrupting the activity of the NF-kappaB pathway, which ensures survival and resistance of CLL cells. This approach may lead to re-sensitization of CLL cells to conventional chemotherapy and novel agents.
A University of East Anglia study found that schools providing clean water report lower absenteeism rates. During the dry season, children without access to clean water were 2.5 times more likely to be absent than those with access. The researchers also highlighted the potential benefits for child health and education.
A comprehensive study found that contagious yawning decreases with age and is not strongly related to variables like empathy or energy levels. However, age was the most important predictor of contagious yawning, accounting for only 8% of variability in the response.
Researchers have developed an on-board emotion detector using embedded cameras to analyze drivers' facial expressions, identifying irritation and anger as risk factors for aggressive driving. The system successfully detected these emotions in most cases, paving the way for potential applications in driver safety and comfort.
TRMM satellite data shows heavy rainfall rates and powerful thunderstorms in the northeast Gulf of Carpentaria, indicating a potential rebirth of Tropical Cyclone Gillian. The system is expected to intensify over the next 24-36 hours, posing gusty winds and heavy rainfall to coastal communities.
A study by Cornell Food & Brand Lab found that offering 5-10 healthy food options and modifying popular items to reduce saturated fats increased revenue and sales. The healthier items accounted for 9.2% of total sales and parental satisfaction also increased.
A new study evaluated the outcomes of Charnley total hip replacements in patients under 50 years old at least 35 years post-surgery. The results showed that a significant number of these patients had functional hip components, despite decreased activity levels over time, primarily due to age and health-related factors.
A study published in Medical Care found that patient requests for specific medications, including brand-name drugs, have a substantial impact on doctors' prescribing decisions. The results suggest that these requests can lead to suboptimal care and increased medication costs.
Researchers at Aarhus University found that patients with blood poisoning are twice as likely to develop a blood clot in the brain or heart. The risk is highest within 30 days of infection, and only 0.2% among the general population.
Scientists discover five new species of armored spiders living in caves in the South China Karst, a UNESCO World Heritage Site. This finds brings the total number of known spider species in China to 4300, with over 2000 caves investigated.
Researchers at UC Davis hope to prove that mobile health technology improves cancer patient care, quality, and reduces costs. The project uses a unique social networking tool to connect patients with their nurse coordinators, family, caregivers, and clinicians.
A study published in the Journal of Food Science found that combining hemp flour with decaffeinated green tea leaves creates a gluten-free cracker with high protein, fiber, and essential fatty acid content. This combination also provides antioxidant properties, making it a nutritious snack option for consumers.
NASA's Aqua satellite captured infrared data on Tropical Cyclone Lusi, revealing it had become a cold-core system with strongest winds spreading out. The storm is expected to bring gale-force winds and heavy rain to Northern New Zealand, particularly around North Cape.
Researchers found a dramatic rise in opioid analgesic prescriptions during US emergency department visits from 2001 to 2010, with some opioids increasing by 668.2 percent. Despite modest increases in painful conditions, the findings suggest a concerning trend that may lead to misuse and addiction.
Researchers have developed a system to produce structural color through microcapsules filled with disordered particles, allowing for the creation of paints and electronic displays that never fade. This technology has the potential to replace toxic synthetic dyes and create ageless colors.
A study of 44 middle-age adults with Type 1 diabetes found that those diagnosed at older ages had weaker brain connectivity compared to those diagnosed earlier. The researchers suggest that further study is needed to understand the impact of early diagnosis on brain function and development.
A recent study identified genetic factors associated with lactase persistence in African populations, which became more prevalent after cattle domestication in Africa. Individuals retaining high levels of lactase enzyme allow them to digest milk sugars in adulthood.
Researchers at Scripps Research Institute found a gene called stumble that helps detect leg-joint angles in fruit flies, similar to human nerve cells. This discovery could improve understanding and treatment of balance and limb movement disorders.
Scientists discover extraordinary diversity and specialization in tropical insects, with each fly having a unique ability to escape parasitic wasp species. This specialization leads to increased niche diversity in the community, revealing that insects are more diverse than thought.
Researchers at Virginia Tech and MIT have developed a computer-aided design tool called GenoCAD to create genetic languages for designing biological systems. The tool helps capture biological rules to engineer organisms that produce useful products or healthcare solutions from inexpensive materials. GenoCAD enables the standardization ...
Researchers have developed a versatile mouse that expresses a fluorescent biosensor, enabling the tracking of diseased cells and drugs in real-time. This technology has been used to monitor Rac activation in various organs in response to drug treatment, providing valuable information on cancer progression.
Scientists have identified a set of proteins called TAFs that may play a role in the development of ovarian cancer. Studies found that these proteins are overexpressed or underexpressed in 73% of tumors, suggesting they could be potential targets for new treatments.
Researchers have developed a new technique for making unnatural amino acids, which are sought after by the pharmaceutical industry for their medical uses. The method employs special ligand compounds to enhance the ability of a palladium catalyst to break carbon-hydrogen bonds.
Researchers at UC Riverside have discovered a new auxin sensing and signaling system localized on the plant cell surface, which explains how leaf epidermal cells form their distinctive jigsaw puzzle-piece shapes. This breakthrough discovery sheds light on the molecular mechanisms underlying various auxin-modulated developmental processes.
The Frank R. Lillie Research Innovation Awards will fund two years of research for $125,000 per award, supporting novel collaborative projects at the Marine Biological Laboratory that aim to transform our understanding of fundamental biological processes and human health.
A recent study published in Liver Transplantation reveals that only 17% of liver transplant centers offer an alibi to potential donors, highlighting the need for standardization. The researchers recommend including written offers of alibis in consent forms to preserve donor autonomy.
Researchers at CU Denver Anschutz Medical Campus will receive $3 million as part of a national effort to study pediatric stroke. The focus is on understanding mechanisms of injury, protection, and repair of the brain following stroke in children, with the goal of training a new generation of pediatric stroke physicians.
Researchers identified mismatch negativity as a potential biomarker of psychosis risk, suggesting that deficits in this brain signal may precede the onset of psychosis. The study found that individuals at clinical high risk for psychosis who developed a psychotic disorder had reduced mismatch negativity compared to those who did not.
A University of Wisconsin-Madison researcher has detected a potential association between soy formula and seizures in children with autism. The study found excess seizures among girls and in the total sample of 1,949 children who consumed soy-based infant formula.
A team of scientists has discovered that a single amino acid difference in histone H3.3 enables it to serve as a memory device for the cell, marking genes that need to remain active. This epigenetic modification acts as a flag, signaling to the cell that genes in the vicinity should be inactive.
Scientists at Max-Planck Institute discover efficient way to brake molecular ion rotation, opening up new possibilities for laboratory-based astrochemistry. By cooling the rotational temperature using a tenuous gas, researchers can study chemical reactions in space more easily.
Researchers identify two rare mutations in the mTOR gene associated with a complete response to everolimus and pazopanib, leading to improved treatment options for patients. The study provides new insights into personalized medicine and targeted therapies for bladder cancer.
A state program reduced falls among elderly Pennsylvanians by 17%, illustrating the effectiveness of using existing aging services to prevent falls. The Healthy Steps for Older Adults program, which provided risk screening and educational information, was found to be a successful tool in reducing falls.
Researchers discovered the mechanisms behind long-term depression, a cognitive impairment contributor to Alzheimer's disease. Chronic inflammation and hypoxia activate microglia, weakening neural connections.
Researchers discovered varied gene expression patterns between male and female athletes, with altered signaling pathways regulating cartilage growth. The findings suggest genetics may play a role in the higher incidence of ACL injuries among females.
Researchers at Johns Hopkins Medicine identified a protein that plays a surprising role in cell migration, which is crucial for cancer cells to spread. The study found that deleting this 'Velcro protein' does not cause single-celled migration, but rather disrupts the organization of epithelial cells.
A Mount Sinai study reveals that GM-CSF protein production is critical for maintaining immune tolerance in the gut, and its deficiency may lead to increased susceptibility to inflammatory bowel diseases. The research suggests that targeting the GM-CSF axis could be a promising strategy for developing effective treatments for IBD.
A new study found that every 15-minute delay in treating ischemic stroke can result in losing a month of disability-free life. On the other hand, speeding up treatment by just one minute can save patients around 1.8 days of healthy life.
Researchers found that joining a gang in adolescence significantly increases risk of incarceration, receiving illegal income, and struggling with drug abuse in adulthood. Former gang members were also more likely to have lower education levels and poorer health.
Scientists discovered that Pichia holds at bay a harmful fungal yeast Candida by secreting material that controls Candida's growth and biofilm formation. This finding holds promise for therapeutic agents to stave off not only thrush but also other life-threatening systemic fungal infections.
A powerful storm system brought drastic temperature changes to the Mid-Atlantic and Northeastern US, with Washington D.C. experiencing a 40-degree drop in daytime temperatures and Buffalo, NY receiving 13.8 inches of snow.
A study published in Physical Review Letters reveals that exchange rate fluctuations can be modeled using the principles of statistical physics. The research demonstrates that market orders and transactions influence price movements in a manner similar to the impact of thermal agitation on particles in a fluid.
Scientists at Brigham Young University discovered a new way to convert natural gas into upgraded liquid alcohol fuel, reducing dependence on petroleum. The breakthrough uses ordinary metals like thallium and lead to trigger the conversion process at lower temperatures.
The number of PSA screenings performed by doctors declined significantly after the 2012 USPSTF recommendations, with a greater impact seen among urologists.
Researchers at Brigham and Women's Hospital have identified certain proteins in osteoclasts that may help destroy cardiovascular calcification by dissolving mineral deposits. The discovery suggests a potential therapeutic avenue for patients with cardiovascular calcification.
A study published in PLOS Pathogens found that a family of fungi called Pichia suppresses the growth of disease-causing fungi like Candida. This antagonism is thought to be responsible for reducing the severity of oral candidiasis in HIV-infected individuals.
A new study suggests that China's coastal regions are no longer the primary destination for migrant workers, as low-educated laborers increasingly find jobs in their home provinces. Meanwhile, educated migrants continue to flock to coastal cities, driven by the concentration of knowledge-based industries and advanced service sectors.
Researchers discovered a specialized mechanism for spatial self-awareness that combines visual cues with body motion, triggering reactions before the conscious brain processes them. This 'visuomotor binding' mechanism is less prone to distractions and may be linked to schizophrenia symptoms and difficulties with prosthetic limbs.
A study found that pre-operative EMG evaluation of donor nerves improves nerve transfer surgery outcomes for patients with brachial plexus injuries. The use of normal donor nerves resulted in greater post-operative improvement in muscle strength and function compared to less robust donor nerves.
A mid-level solar flare, classified as an M9.3 flare, was captured by NASA's SDO on March 12, 2014. The flare was emitted by an active region on the sun's surface and may have disturbed Earth's atmosphere and affected GPS signals.
A Cornell professor's new research in Science has found evidence of more complexity in the relationship between flies and their predators, the parasitic wasps. The study revealed that most wasp species are extreme specialists, with offspring only able to survive in one specific fly species.
The CU-Boulder toilet uses concentrated sunlight to heat human waste, disinfect pathogens, and produce biochar, which can increase crop yields and sequester carbon dioxide. The project aims to improve sanitation in developing countries, reducing deaths from food and water tainted with fecal matter.
A phase I trial found a complete response for 14 months to everolimus and pazopanib in a patient with advanced bladder cancer and rare mTOR genetic mutations. Genomic profiling revealed two alterations that activated the mTOR-mediated cell signaling pathway, rendering the cancer sensitive to the mTOR inhibitor.
A soft-bodied robotic fish with a flexible spine can mimic real fish swimming motions and perform rapid accelerations. The innovative design enables the robot to adapt to various environments, showcasing advancements in soft robotics.