A new study published in Diabetologia shows that taking blood pressure medications at bedtime halves the risk of developing type 2 diabetes in hypertensive patients. The research found a 57% decrease in risk with nighttime treatment compared to morning treatment.
A new study in the Journal of Public Policy & Marketing suggests that both numeric calorie labels and traffic lights are effective ways to encourage consumers to make low-calorie choices. The research found that employees who received either type of label made food selections with 10% fewer calories.
A study published in the New England Journal of Medicine found that letrozole did not improve pregnancy rates and live birth rates for women with unexplained infertility, but clomiphene remained the best option. Clomiphene enabled production of more eggs and hormones, while gonadotropin had the highest rate of pregnancy and live births.
A team of researchers used a toddler-like robot to study infant-parent interaction, finding that babies intentionally smile to elicit a response from their caregivers. By analyzing the timing of these smiles, they discovered a statistically strong correlation between intentional smiling and mutual smiling in both humans and robots.
Frustrated magnets can produce tiny magnetic vortices, known as skyrmions, that may be used in memory storage. The discovery opens up a new class of materials for scientists working on skyrmionics, which aims to build logic devices based on skyrmions.
Yale University scientists have designed a new chemical compound that mimics the properties of nitrogenase, an enzyme responsible for natural nitrogen fixation. The findings could lead to the development of synthetic catalysts that turn nitrogen into ammonia, reducing transportation and production costs.
A new study in the Journal of Marketing suggests that online idea-generating platforms should customize their design based on consumers' domain-specific knowledge. Consumers with extensive industry knowledge generate better ideas when not shown other users' ideas, while those with little knowledge benefit from concrete cues.
Tropical Storm Ida's wind shear is pushing clouds and strongest storms to the east and northeast of its center, with coldest cloud tops reaching -63 degrees Fahrenheit. The storm remains over open ocean, with forecasters predicting a slow eastward motion followed by a turn towards the north later on September 24.
Researchers developed a rotaxane gold catalyst with enhanced properties, which can be controlled by adding acid or metal ion cofactors. The catalyst's shape changes with different ions, leading to varied reaction products and suggesting a potential method for tailoring catalysts.
Scientists from UC San Francisco capture and study individual metastatic breast cancer cells, finding they express genes similar to mammary stem cells, which could lead to targeted therapies. The research suggests a new approach to understanding how cancer spreads and developing effective treatments.
A study by Iowa State University found that digital textbook analytics can accurately predict student outcomes, offering a more individualized measure than traditional GPA-based assessments. By tracking students' reading time and engagement, instructors can tailor their instruction to better support struggling learners.
A NAMS panel recommends behavioral approaches like cognitive-behavioral therapy and clinical hypnosis as effective in reducing hot flash symptoms. Nonhormonal prescription medications, such as SSRIs and gabapentinoids, are also recommended for their mild to moderate improvements.
A 9,000-year-old case of human decapitation has been discovered in Lapa do Santo, Brazil, featuring amputated hands and v-shaped cut marks on the jaw and vertebrae. The remains are believed to demonstrate sophisticated mortuary rituals among hunter-gatherers in the Americas.
The BMJ investigation found that the expert report underlying the latest US dietary guidelines fails to reflect relevant scientific literature, risking a misleading picture. The guidelines affect millions of Americans and food labelling, education, and research priorities.
Researchers at Sahlgrenska Academy found that the Fugl-Meyer assessment scale can predict stroke patients who will develop upper limb spasticity within one year. This allows for early treatment to minimize pain, impaired function, and other repercussions of spasticity.
Researchers at University of Virginia Health System identify two new cancer-causing gene mutations in MCM8 and MCM9 genes, which may be particularly susceptible to cancer-fighting drugs like cisplatin and olaparib. These mutations could lead to more targeted and effective treatments for lung and prostate cancers.
A new metal-based compound, Compound 5, has been developed to destroy kidney cancer cells while leaving normal cells unharmed. The compound, which incorporates both titanium and gold, has shown excellent promise in pre-clinical models, outperforming the FDA-approved drug Cisplatin.
A brain circuit has been identified that processes the 'when' and 'where' components of memory, separating location and timing into two streams of information. This discovery sheds light on how the brain represents time and place in episodic memories.
A team of researchers used an online classification system, Space Warps, to identify 29 new gravitational lens candidates. The citizen scientists analyzed 430,000 images and helped the researchers uncover potential lenses that algorithms may have missed.
Researchers estimate that 47% of edible US seafood supply is lost annually, mainly from consumer waste. The study suggests that reducing waste can support increased seafood consumption without stressing aquatic resources.
Researchers discovered that flu viruses gain ability to spread through air by adapting to bind to specific human receptors, with the soft palate playing a key role in this process. The findings provide insight into how flu viruses evolve airborne transmissibility and can help identify viruses with potential to cause global outbreaks.
A biofilm with antimicrobial and anti-inflammatory properties has been developed to prevent or control post-operative infections on medical devices. The film reduces inflammation and prevents bacterial and fungal infections, offering a promising alternative to antibiotics.
Researchers at UW linked two human brains to play a question-and-answer game via direct brain-to-brain connection. Participants successfully identified objects in 72% of real games, outperforming control rounds.
A new safe and sustainable cathode material has been identified for low-cost sodium-ion batteries, addressing instability issues and paving the way for commercialization. The material's structure allows for sodium to be inserted and removed while retaining its integrity, enabling further development of sodium-ion batteries.
A new study reveals that demarketing can be an effective way to reduce carbon footprint by altering consumer values. Materialistic individuals tend to decrease their consumption after reading a report about overconsumption, whereas those with low materialism may increase their consumption in response to social norms.
Scientists at Joint Quantum Institute successfully control orbital angular momentum of neutron waves, a fundamental property of matter waves. The achievement uses a counterintuitive property of neutrons to twist the phase of their wavefunction, enabling potential applications in neutron imaging and quantum information processing.
Researchers developed a novel approach using liquid crystals to detect neuro-degenerative diseases by detecting the protein fibers implicated in their development. The system shows extremely high sensitivity and could enable earlier detection at a lower cost.
A mathematical analytical tool developed by University of Cincinnati scientists can predict strontium ratios in surface water, soil, vegetation, fish, and mammal skeletal tissues with high accuracy. The tool is most successful when applied to mammals, making it a valuable tool for ecological and paleoecological research.
Scientists have developed a method to produce a palladium-based nanomaterial that can efficiently break down formic acid into hydrogen and carbon dioxide. The new process surpasses existing heterogeneous catalysts in efficiency, also eliminating the production of carbon monoxide.
Researchers have found an explanation for the key experiment in Japan's spin caloritronics field. They applied measurement methods to generate pure spin currents in magnetic isolators, differing from original expectations.
The Suomi NPP satellite observed a large and elongated circulation of Tropical Storm Dujuan, with cloud top temperatures as cold as -63F/-53C indicating strong storms. The storm is expected to intensify and reach peak winds of 110 knots on September 27-28.
The University of Michigan released its final report on high-volume hydraulic fracturing in Michigan, providing an analysis of policy options for the state's natural gas and oil extraction process. The report includes recommendations for public participation, water resources, and chemical use related to high-volume hydraulic fracturing.
A participant with complete paralysis regained walking ability using a brain-controlled system that utilizes electroencephalogram signals. The study, published in Journal of NeuroEngineering and Rehabilitation, demonstrates the feasibility of non-invasive leg muscle stimulation using direct brain control.
A new study by Felipe Thomaz and Vanitha Swaminathan found that marketing alliances generally lower equity risk. However, this benefit is conditional on the alliance being new and the partner's existing network not being too interconnected.
Most states do not consider ignition interlock devices a severe enough punishment for first-time DUI offenders, despite their effectiveness in reducing arrest rates and fatalities. The study found that only less than half of states mandate the use of these devices for first-time offenders.
The American Society for Cell Biology announced the winners of the 2015 Kaluza Prizes, recognizing outstanding graduate student bioscience research. Ten young scientists received cash and travel awards for their contributions to cell biology.
A new study measures coral-reef ecosystem condition, predicts key threats, and evaluates human stressors in Micronesia. The results reveal only 42% of major reef habitats exceed thresholds for conservation efforts.
Researchers find domain-specific measures of self-control produce better predictions for consumer behavior on specific behaviors like eating and shopping. The study recommends adapting a general measure to the context at hand for more accurate assessments.
The Parsortix system demonstrated comparable speed in capturing CTCs for prostate cancer compared to existing methods, while also showing improved capture of CTCs responsible for metastatic cancer. The technology offers a promising approach to detect and treat metastatic cancer.
Researchers developed nanoparticles that deliver allergens to specific cells, reducing side effects. The new approach could lead to safer and more effective treatments for allergies and other conditions.
A study found that people with delayed orthostatic hypotension are at risk of progressing to a more serious condition, Parkinson's disease, or dementia. Over 10 years, 54% of participants with the delayed condition progressed to orthostatic hypotension and 31% developed a degenerative brain disease.
Researchers at Scripps Florida Institute have been awarded $6 million to develop an innovative HIV/AIDS vaccine that has shown promise in animal models. The approach works by blocking key sites on the virus's surface, preventing it from attaching and invading human immune cells.
A study found that telehealth visits, whether by telephone or video, can identify veterans requiring in-person assessment or further care. The majority of veterans preferred telehealth visits due to increased convenience and shorter travel distances.
A new procedure called CAUSEL uses genetic fine mapping, epigenomic profiling, epigenomic editing, genome editing, and phenotypic analysis to pinpoint disease-causing variants in non-coding genomes. The approach has shown promise in identifying disease-associated variants in prostate cancer risk.
A NASA study found a significant decline in microscopic plant-life, including diatoms, in the world's oceans over the past 15 years. The reduction may impact the ocean's ability to draw carbon dioxide from the atmosphere and store it for long-term, leading to climate change.
A new study published in the Journal of Oncology Practice found that patients participating in stage III renal cell cancer drug trials are often younger and healthier than those who ultimately receive the drugs. The study highlights concerns about the direct applicability of trial data, particularly for patients with more advanced canc...
Researchers have designed enzyme-functionalized micromotors that can rapidly remove carbon dioxide from water and convert it into a usable solid form, potentially helping to mitigate ocean acidification and global warming.
Researchers discovered the soft palate plays a key site for flu virus emergence and transmission, binding preferentially to mammalian-type SA, which is associated with airborne transmission. The finding may aid efforts to define properties governing flu virus transmissibility and predict pandemic potential.
A recent study from Dana-Farber Cancer Institute found that nearly one-third of families with children undergoing cancer treatment experience food, housing, or energy insecurity. The research also revealed that many adults who support their families lose their jobs or take leaves due to their child's illness.
Researchers developed a selective synthesis method using an enzyme from E. coli, assembling simple molecules to form complex carbohydrates with few steps and no waste, replicating prebiotic conditions. The process has great potential in chemistry for obtaining natural molecules and active ingredients.
Stillbirths are expected to increase by 52 million between now and 2035 if no action is taken. Experts advocate for clear targets to prevent stillbirths in national and global health plans.
Researchers call for improved early miscarriage diagnosis guidelines as a new study reveals the current standard may lead to misdiagnosis. A two-scan approach up to 14 days apart can improve accuracy and reduce false positives.
A study published in Neuron found that the rostrolateral prefrontal cortex (RLPFC) plays a crucial role in internally monitoring and guiding our behavior through sequences of tasks. By disrupting this region, researchers observed an increase in errors, highlighting its importance for cognitive control.
A/Prof Shane Grey's team aims to make significant improvements in islet transplantation therapy, making it a clinically realistic option for more individuals with type 1 diabetes. They focus on calming the immune response of patients to islet transplantation, which could lead to treated individuals living drug-free in the long term.
A study in the Journal of Marketing found that higher financial leverage leads to decreased customer satisfaction due to reduced advertising spending. The impact of leverage is economically significant, resulting in a 0.47-point decrease in customer satisfaction equivalent to an estimated $26 million loss in net operating cash flows.
A new study published in the American Journal of Preventive Medicine found that increased risk of mortality from long periods of sitting was only associated with very occasional fidgeters. Fidgeting, even for moderately or very active women, may offer enough of a break to counteract adverse health impacts.
Researchers found a previously unknown code within the genetic code that affects protein assembly speed, leading to different functions of identical proteins. This discovery has significant implications for understanding human disease-causing mutations.
Researchers found that children's short legs struggle to push off the ground during running due to limited muscle contraction time. This discovery led to a new model explaining kids' clumsy movements, which is supported by calculations of muscle activation and gait parameters.
Scientists have discovered a 'bucket brigade' that brings liquid to Titan's north pole, creating lakes and seas. Meanwhile, NASA's Kepler telescope has opened up possibilities for exoplanet studies. Research also explores abrupt shifts in phenology and vegetation productivity under climate extremes.
Tufts University researchers developed a new method to create high-resolution, 3D structures in silk protein hydrogels using low-energy ultrafast laser technology. The technique allows for scalable patterning of pores and channels with diameters between 10 and 400 microns.
Ocean cells differentiate environmental contexts, which are then sent to the hippocampus for memory formation. The entorhinal cortex plays a crucial role in context-dependent learning, and understanding Ocean cells' contribution may help diagnose Alzheimer's disease.
Researchers found an O-type star, NGC 1624-2, has the largest known magnetosphere, trapping gas and creating a massive aura of hot, dense plasma. The star's powerful stellar winds are up to 100,000 times denser than our Sun's solar wind.
The university will train 100 students annually in Screening, Brief Intervention, and Referral to Treatment (SBIRT) for substance abuse behaviors. SBIRT is an integrated public health approach to delivering early intervention and treatment services.
Scientists have created tire-grade rubber that can heal itself, potentially extending the lifespan of tires. The material, developed by Amit Das and colleagues, heals at room temperature and can withstand stresses of up to 754 pounds per square inch.
Experts recommend a second ultrasound scan within 7-14 days after initial scan to avoid misdiagnosis of healthy pregnancies. The study analyzed 2,845 women's scans and provides new criteria for repeat scans.
A new study suggests that the universe was 'cooked' at just the right speeds to generate a rich and complex structure. The findings contradict the widespread belief that faster quantum phase transitions generate more structure.
Researchers have developed a drug that disables C. difficile toxins, preventing intestinal damage and allowing the gut to repopulate with healthy bacteria. The breakthrough could lead to rapid human trials for treating deadly C. difficile infections.
Researchers found that two wasp species preferred different types of manure, highlighting the importance of identifying fly species for effective control. The study provides guidance on releasing wasps at the right time and frequency to manage horse flies sustainably.
Researchers have identified a molecular pathway that explains how tamoxifen-resistant breast cancer cells develop. The 'feedback loop' involves the HOXB7 protein, which helps activate genes that promote cancer growth. Targeting MYC protein, which is involved in this pathway, may lead to new treatments for tamoxifen-resistant cancers.
A group of scientists from seven international laboratories failed to replicate the STAP study, which claimed to turn ordinary cells into pluripotent stem cells. Computational analysis revealed significant genomic inconsistencies, including different genders and mixtures of embryonic and placental stem cells in some experiments.
Researchers from Uppsala University and IVPP in Beijing combined palaeontological and genomic data to determine that enamel originated in the skin and colonized the teeth much later. The study found that ganoine, an enamel-like tissue, is expressed in the skin of certain fish species, suggesting a possible connection between the two.
Two US studies published in The BMJ reveal a significant increase in drugs approved via expedited pathways, raising concerns about efficacy and safety. The findings suggest that most new drugs may not be significantly more effective than existing products.
A new chemical process developed by WPI's Marion Emmert may significantly improve pharmaceuticals' ability to bind with biological targets, producing therapeutic effects. The team aims to streamline production of existing drugs like Asacol, shortening its manufacturing time.
The Hong Kong Polytechnic University has developed a novel eco-friendly manganese dioxide ink for energy storage devices, which exhibits high capacity and power density. The MnO2 ink can be used to produce light, thin, flexible energy storage devices with improved performance and lower production cost.
The NASA Operation IceBridge campaign is conducting overlapping flights in Antarctica and the Arctic to track changes in polar ice conditions. The team aims to compare measurements taken during spring and summer campaigns, providing insight into ice thickness variations within the year.
NOAA has awarded grants to three companies to develop ocean acidification-resistant abalone strains, genetics-based selective breeding protocols for mussels, and sustainable multi-species marine algal aquaculture in Maine. These projects aim to tackle significant obstacles in US aquaculture and explore novel solutions.
A study published in PLOS ONE suggests that neurogenin 3-expressing cells in the exocrine pancreas have the capacity to become insulin-producing beta cells. This discovery may lead to novel drug therapies to replenish cells destroyed or damaged by diabetes.
Researchers at TUM and Georgetown University have discovered a common gatekeeping system for tinnitus and chronic pain, which may play a central role in the development of both conditions. The study found significant loss of gray matter and compromised circuit function in regions important for emotional experiences.
The adolescent brain is more susceptible to forming new memories, experiencing social stress, and engaging in risky health behaviors. Research suggests that adolescence may be a sensitive period for recovery from negative experiences and that alternative treatments might be needed for anxiety disorders.
The WHO classified glyphosate as a probable carcinogen, but a German review found it unlikely to pose a carcinogenic risk. Roundup's diminishing effectiveness has led to the development of resistance by weeds, prompting farmers to seek alternative methods and products.
A new study by Vanderbilt University Medical Center found that 76% of patients accepted online postoperative care as the only form of follow-up, while 68% reported equal effectiveness between online and in-person visits. The researchers believe designing tools for online care is key to determining when in-person care is needed.
A report by EMBO examines the potential benefits and challenges of using gender quotas to achieve better gender balance in academia. The study suggests that quota systems, such as cascade models, can be effective in increasing female representation in higher academic positions.
Researchers at Ludwig-Maximilians-Universität München have developed a novel photonic crystal that changes color in response to moisture, enabling humidity-sensitive contactless control. The nanosheet-based material displays unparalleled sensitivity and response time, making it ideal for next-generation touchless navigation systems.
A study by UC Davis researchers found that bird diversity in the Central Valley's riparian areas is similar between summer and winter, with genetic diversity even higher in winter. Neotemperate migrants from Canada fill the gap during winter months.
Researchers have found evidence of giant killer lizards coexisting with early Australian humans around 50,000 years ago. The discovery sheds light on the potential drivers of megafauna extinction during this period.
Researchers have discovered that brain malfunctions in key areas, such as the nucleus accumbens and ventromedial prefrontal cortex, contribute to the development of tinnitus and chronic pain. These findings hold promise for developing targeted therapies for these debilitating disorders.
Researchers have engineered viruses to target specific bacteria, offering a new approach to combatting human disease. The customizable viruses could be used to treat various infections, including those caused by E. coli, Yersinia, and Klebsiella bacteria.
A new study published by the NIH finds that clomiphene is more effective than letrozole for treating unexplained infertility, resulting in more live births. The study compared over 900 couples undergoing fertility treatment and found that clomiphene resulted in higher pregnancy rates and fewer multiple pregnancies.