Researchers found a significant increase in HCV infections among HIV-positive MSM, with the rate of new infections tripling between 1991 and 2010. The study also identified risk factors, including unprotected anal sex and sex while high on non-injected drugs.
The University of Maryland has received a $1.8 million grant from the National Institutes of Health to improve Bioconductor, an open-source data visualization software used in genomic marker identification for cancer and other diseases.
Researchers at UC Berkeley have identified nonstructural protein 1 (NS1) as a key culprit responsible for fluid loss and resulting shock in severe dengue virus infections. Blocking this protein in mice protected them from lethal effects, suggesting it could be a prime target for drugs and vaccines.
A recent study published in Nature Communications reveals that protein lamin A plays a crucial role in maintaining genomic structural stability by forming 'cross-links' that limit genetic material's freedom of movement within the nucleus. This creates a stable and linked polymeric structure promoting chromosomal integrity.
Smells trigger immediate emotional responses, and olfactory branding can supplant traditional marketing signals in settings like hotel lobbies. Over 41% of guests at ITC Sonar Luxury Hotels in Kolkata agreed that scent is a key factor in enjoying their stay.
A study of nearly 60,000 women who received synthetic vaginal mesh slings for stress urinary incontinence found a low risk of needing second surgery for mesh removal or revision. High-volume surgeons performed fewer complications, and multiple mesh-based procedures increased the risk of complications.
Research from Georgia Tech reveals that Twitter users adopt formal tone when using hashtags to reach a wider audience, while using @ symbols with smaller audiences or local language. The study shows geographical differentiation in online language, with regional lingo used in messages targeting specific cities.
Rice University researchers have developed a new technique to characterize the space within porous materials, allowing them to measure dimensions and dynamics at the nanoscale. This breakthrough could improve protein separation processes for the pharmaceutical industry.
Justin Ichida's lab will use cellular reprogramming to transform blood cells of ALS patients into motor nerve cells in a Petri dish. The goal is to rescue the cells by exposing them to normal levels of C9ORF72 protein and reveal its protective mechanism against ALS.
New insights into Mercury's movements and interactions with the solar system reveal its unique composition. Researchers reevaluate New Zealand's Alpine Fault after seismic data showed it becomes flatter at depth, providing new information for geological studies.
In a study published in PLOS ONE, researchers found that barbastelle bats emit two different types of weak echolocation signals alternately through their nose and mouth. These 'stealth echolocation' signals facilitate prey detection while minimizing environmental disturbance.
Researchers at Imperial College London have created a fluorescent molecule that can reveal the presence of quadruplexes in living cells. This breakthrough could be a game changer to accelerate research into these DNA structures and identify new compounds that can bind to them, potentially leading to new cancer treatments.
A team of researchers is using advanced computational models to better understand multiphase flows in porous media. They aim to improve carbon sequestration, mitigate climate change, and optimize energy extraction. By analyzing data from experiments and simulations, the team is developing a multiscale framework to model complex systems.
A new method of harvesting and growing lung stem cells has been developed by researchers at NC State University, which could provide an effective treatment for idiopathic pulmonary fibrosis (IPF). The study used a multicellular spheroid environment to enrich adult lung stem cells, which showed promise in mice trials with reduced inflam...
A Kansas State University research project will investigate the interaction between viruses and the immune system, focusing on poxviruses that could potentially become deadly diseases like smallpox. The study aims to predict future host ranges and develop new strategies for disease control.
Researchers found that when people took pride in an accomplishment, they were more likely to continue making disciplined choices throughout the day. However, when people considered a self-control goal before feeling proud, they were more likely to indulge in rewards and have less self-control.
A University of Cincinnati study found that black voters are more likely to support black Democratic candidates, but may consider voting for a Republican candidate if they know the candidate's party affiliation. The study suggests that building a Republican coalition with black voters is challenging due to ongoing racial and partisan t...
Researchers reveal that Saturn's F ring and its shepherd satellites, Prometheus and Pandora, formed from the collision of small satellites with a dense core. This study sheds light on the formation process of satellite systems in our solar system and beyond.
Researchers have found a new strategy to eliminate HIV by reactivating latent infected cells using a class of drugs called Smac mimetics. The approach, which has shown promising results in clinical trials for cancer, may lead to a safe and effective treatment to cure the virus.
Researchers develop a way to make drugs degrade before reaching drinking water, reducing environmental contamination. They made tweaks to propranolol, a commonly used beta blocker, allowing it to break down more easily into harmless compounds.
A clinical trial using Pembrolizumab plus chemotherapy found the treatment to be safe for patients with advanced small cell and non-small cell lung cancer. The study, led by Dr. Glen Weiss, presented initial results from 12 lung cancer patients enrolled in the 'PembroPlus' clinical trial.
A team of researchers from Kobe University has developed a novel method to quantify the proportion of native and non-native genotypes in aquatic species. By analyzing environmental DNA (eDNA) from water samples, they were able to detect the presence of invasive non-native strains in rivers and reservoirs of western Japan.
Scientists discovered microbes in Kabuno Bay that oxidize iron through a unique photosynthesis process, depositing large iron formations. This finding supports the theory that microorganisms played a key role in shaping Earth's chemistry and evolution of life.
A panel of world experts recommends annual brain health screenings for individuals 70 and older, citing high rates of memory problems among this age group. Lifestyle changes, such as a Mediterranean-type diet, exercise, and intellectual activities, can slow cognitive decline.
Research by Ben-Gurion University shows that Jewish mothers employ various protective strategies to mitigate the risk of eating disorders in their daughters, including filtering, positive reinforcement, and discussion. These methods help build resilience and promote a positive body image.
Researchers discovered how capsaicin interacts with cell membranes, finding that it lodges near the surface and can cause membranes to come apart. This insight may lead to novel tools against cancer or other conditions. The study appeared in ACS' The Journal of Physical Chemistry B.
Researchers used Photovoice method to study food environments and eating habits of 9- to 13-year-old children eligible for SNAP. The method paired photographs with interviews, revealing food insecurity and the influence of family, peers, and parents on diet.
A systematic review of animal studies on MVA85A vaccine found insufficient evidence to support its effectiveness as a BCG booster. The delay in publishing the largest monkey trial with the longest follow-up also raised concerns about scientific integrity.
A comprehensive review of treatment options for PMDD identified selective serotonin reuptake inhibitors (SSRIs) as the first-line treatment, effective in reducing symptoms. For women who experience an inadequate response to SSRIs, alternative treatments such as antidepressants, anti-anxiety drugs, and oral contraceptives are recommended.
Researchers mapped social vulnerability at the district level, identifying three clusters of most vulnerable districts containing over 1 million people. The study highlights the importance of addressing water quality, food insecurity, and access to medical care to prevent Ebola infections and deaths.
Researchers at Linköping University have discovered that disorder and short-range intermolecular aggregation can enhance the conductivity of conjugated polymers. This finding opens up new avenues for developing faster electronic components.
The deployable tower assembly (DTA) is a crucial component of the James Webb Space Telescope, enabling its instruments to be separated from the spacecraft bus and sunshield after launch. This allows the sunshield to unfurl and shade the telescope and instruments from radiant heat and stray light.
A new study reveals that patients with lumbar spinal stenosis prefer pain relief to improved mobility, defying medical community assumptions. Researchers surveyed 269 patients and found that 79% chose pain reduction over increased physical function.
A team of international researchers has developed recommendations to preserve the local environment in China's Xinjiang region, which produces ten percent of global cotton production. Sustainable land use practices and reforestation are key to reducing soil salination and preserving groundwater supplies.
A new study reveals that iconicity is prevalent across the vocabulary of spoken languages, including English and Spanish. The researchers found that words learned in childhood are the most iconic, which helps children grasp the concept of a word. The study suggests that iconicity plays an important role in word learning and development.
A new report from the University of East Anglia found that mothers who quit smoking in pregnancy are more likely to light up again if they feel stressed and lack support. The study highlights the importance of partner support, social influences, and women's beliefs about smoking in preventing postpartum relapse.
Physicists at MIT have found a phenomenon described as a 'ring of exceptional points' produced by the Dirac cone, potentially leading to applications in powerful lasers and precise optical sensors. The discovery represents the first experimental demonstration of this phenomenon.
A bioelectronic nose that mimics the human nose can detect traces of bacteria in water by smelling it, without complex equipment. The sensor is sensitive to low levels of contamination, making it more useful than existing methods.
Researchers developed an Android sleep monitoring app widget, SleepTight, that boosted daily sleep diary information entry and self-reflection among users. The widget's visual reminders and lock screen placement increased user interaction with the data, leading to better understanding of sleep patterns and behavior.
Researchers at Ludwig-Maximilians-Universität München develop efficient synthesis of epicolactone, a complex natural product produced by the endophytic fungus Epicoccum nigrum. The 8-step pathway reveals how the molecule is assembled and provides insight into its biochemical significance.
Scientists have developed a network of energy-harvesting sensor nodes equipped with onboard cameras that can automatically determine each camera's pose and location. This capability enables large-scale sensor networks to operate without batteries or external power, making them ideal for the Internet of Things (IoT) applications such as...
A team of MSU researchers, led by Sarah Evans, will study how plants interact with microbes to obtain nitrogen in abandoned farmlands. The goal is to maximize biofuel yields while minimizing fertilizer use and preserving soil health.
Tropical Storm Etau drenched central Japan with intense rainfall, with GPM satellite measurements showing up to 88 mm/h rain rates. The storm's remnants are expected to transition northwestward off the Japanese coast.
NASA's RapidScat instrument captured the strongest sustained winds in Tropical Storm Jimena near 25 meters per second on its northern side. The storm is forecast to weaken and turn west by September 10, affecting the Hawaiian Islands with large swells and surf.
Researchers at Kobe University identified novel chemosensory proteins in ant antennae, revealing cooperative modes of operation and recognition of individual information. These findings provide a starting point for elucidating the molecular mechanisms supporting complex ant societies.
A study published in Current Biology reveals that lycaenid butterfly larvae can control the behavior of ants by supplying them with nectar rich in sugars and amino acids. This manipulation reduces locomotor activity and increases aggression in the ants, suggesting a selfish strategy to maintain mutualism.
Geneticists identify a gene called MANTLED, which helps determine the fate of sexual organs and causes male organs to develop instead as female organs. The mutation leads to plants with worthless fruit, resulting in millions of dollars in spoilage.
Celeste is a hierarchical model designed to catalog stars, galaxies and light sources in the universe, enabling astronomers to identify promising galaxies for spectrograph targeting and better understand Dark Energy. The model aims to improve data analysis methods, significantly reducing the time and effort spent working with image data.
Scientists identified 'nicotine choosers' and 'avoiders' in a study of 18 healthy adults who had never smoked. The researchers found that some individuals prefer the effects of nicotine, while others avoid it due to genetic or metabolic vulnerabilities.
Researchers used the Atacama Large Millimeter/submillimeter Array (ALMA) to locate compact regions within the nearby dwarf irregular galaxy Wolf--Lundmark--Melotte that can emulate larger galaxies' star-forming environments. These discoveries shed light on how dense star clusters can form in low-density, gas-poor galaxies.
Researchers found that phytoplankton organic waste can stimulate cloud droplets to freeze into ice particles, affecting global climate and influencing temperature. This discovery helps improve weather models and climate predictions.
Researchers aim to identify exRNAs as biomarkers for severe hemorrhagic stroke and risk of subsequent traumatic brain injuries. The study could lead to new treatments and improved outcomes in patients with hemorrhagic stroke.
NASA's RapidScat observed hurricane-force winds extending about 30 miles from the center of Hurricane Linda. The storm is rapidly weakening due to decreasing central pressure and cloud top temperatures warming.
Researchers found a network of DNA sequence variations associated with high survival rates among long-lived smokers, suggesting that genetics play a role in stress resistance and genomic stability. These genetic markers were also linked to a nearly 11% lower cancer prevalence.
A study found that major postoperative complications significantly contribute to prolonged hospital stays, while delirium contributes to adverse outcomes including length of stay, institutional discharge, and rehospitalization. Delirium was found to exert the highest attributable risk compared with other adverse events.
A new study suggests that mindfulness meditation can make memories less accurate, leading to confusion between real and imagined experiences. Participants who engaged in a 15-minute mindfulness meditation session were more likely to falsely recall words from a list, even when the list did not include the actual word.
A new study reveals that nearly half of testicular cancer risk comes from inherited genetic faults, significantly higher than in most other cancer types. The research suggests testing for specific genetic variants could help identify patients at substantially increased risk and potentially lead to prevention methods.
Researchers investigated ocean temperature changes over centuries using climate models and fossil records. They found that volcanic eruptions caused progressive cooling until the Industrial Revolution, which marked a shift towards global warming. Understanding past climate patterns can provide insights into future climate changes.
Participants focused on inherent traits, rather than external factors, as explanations for wealth disparities. Simple explanations can alleviate feelings of uncertainty and anxiety, leading people to see societal disparities as fair.
The world's grassy biomes are under threat from conversion to agriculture and tree planting, which can lead to ecosystem degradation. Protecting these areas is crucial for preserving biodiversity and carbon storage capabilities.