Researchers at University of Utah Health discovered sustained connections between brain regions in individuals with autism. The study found that these prolonged connections may contribute to the symptoms of autism, including social dysfunction and difficulty shifting between activities.
Researchers discovered that BH4 regulates T cell activity, suppressing inflammation in autoimmune conditions and enhancing responses in cancer. A new therapeutic approach targets the same pathway to treat a range of diseases.
New research found that overflowing crater lakes on Mars carved canyons rapidly, possibly in weeks, using high-resolution satellite images. This process likely played a major role in shaping Mars' surface without plate tectonics.
A team at University of Washington demonstrates an innovative approach to bridge AFM and big data, offering better spatial resolution and accuracy. By using sequential excitation strategy, they deduce physical insight from PCA data and speed up analysis by orders of magnitude.
A study found significant changes in grey matter structure and deep brain structures after a season of high school football, which may lead to long-term cognitive decline and neurological disorders. The researchers used MRI scans to examine brain microstructure and correlation with head impacts.
Research found that static activities, such as strength training, were more strongly associated with reducing heart disease risks than dynamic activities like walking and cycling. Both types of physical activity appeared to be heart healthy, even in small amounts, at the population level.
Researchers from Ruhr-University Bochum have developed a new catalyst using mineral pentlandite to convert carbon dioxide into valuable source materials. The catalyst's stability and ability to produce synthetic gas mixtures make it a promising approach to combat climate change.
Forests in the Pacific Northwest are less vulnerable to drought and fire due to climate conditions. Modeling suggests water-limited forests in the Rockies will be most affected by future drought-related mortality.
Researchers studied electronic structures of van der Waals heterostructures under applied vertical electric field, revealing Coulomb interaction's impact on bandedges. This nonlinear variation is attributed to interlayer charge transfer, essential for nanoelectronic device applications.
Researchers found that those who used an average of 15 strategies when eating out had fewer reactions, while non-reactors only used six. People can minimize risk by using multiple strategies such as ordering simple ingredients and checking food before eating.
Researchers found that ants select medium-sized soil grains with quartz over feldspar for their structures, potentially altering palaeoclimatic data. This study highlights the importance of considering bioturbatory action in paleontological analyses.
Researchers at NSLS-II produce 3D images of a single bacterial cell's chemical composition, identifying calcium and zinc distributions. The technique demonstrates high-resolution imaging capabilities for understanding cellular processes and developing medical treatments.
The study reveals that TIM chaperone proteins facilitate the transport of channel and transporter proteins across the outer mitochondrial membrane. The ring-shaped chaperones have six water-repellent brackets to prevent protein aggregation, a common cause of diseases like Alzheimer's and Parkinson's.
A Cleveland Clinic genetic analysis found that excess fat itself is harmful to cardiovascular health, increasing the odds of Type 2 diabetes by 67% and coronary artery disease by 20%. The study used genetic data from over 880,000 participants, suggesting a significant association between obesity and these conditions.
Researchers found that supplementing telephone counseling with access to nicotine-replacement patches and moderate financial incentives significantly improves smoking cessation outcomes in the Medi-Cal population. The study also suggests that modest financial incentives can be an effective intervention for low-income populations.
Researchers found LZTR1 contributes to human diseases by acting as part of ubiquitin ligase complex that mediates conjugation of ubiquitin to RAS proteins, reducing its activation and downstream signalling. This discovery may lead to novel therapeutic approaches for RAS-driven diseases.
Researchers have discovered universal energy transfer and dissipation scaling laws in impact dynamics of dust agglomerates under microgravity conditions. The findings apply to both porous and dense clumps of dust grains, revealing a surprising level of consistency in their response to impacts.
A study of 128 mothers found that children whose parents sucked on their pacifiers had lower IgE levels, indicating a reduced risk of allergies. The effect was most pronounced between 10-18 months of age and may be due to the transfer of beneficial microbes.
Researchers have discovered a new compound, ancistrolikokine E3, from a Congolese rainforest vine that effectively targets and kills pancreatic cancer cells. The compound inhibits the Akt/mTOR pathway and autophagy pathway, leading to dramatic changes in cell morphology and preventing metastasis formation.
Researchers discovered how filamin A and Drp1 interact to facilitate mitochondrial fission under hypoxic conditions, leading to heart failure. The study found that cilnidipine prevents this damaging process, preserving heart function after a heart attack or in cardiovascular disease.
Researchers found a strong association between maximum body mass index over 24 years and risk of death. The study suggests that obesity prevention is crucial in reducing the risk of early death.
Children of caregivers with poor asthma knowledge were four times more likely to have a prolonged hospital stay, according to new research. The study found that caregivers who received education on asthma management and inhaler technique showed significant improvements in their knowledge and ability to care for their child.
Researchers successfully established an immortalized cell line derived from the critically endangered Okinawa rail. The use of the K4DT method, which involves co-expressing mutant CDK4, Cyclin D, and TERT genes, significantly extended cellular division and immortalization in avian cells. This breakthrough paves the way for further func...
A newly published mouse model of Facioscapulohumeral muscular dystrophy (FSHD) has been developed to test potential therapeutics. The TIC-DUX4 mice express DUX4 only when exposed to the drug Tamoxifen, allowing researchers to control gene expression and study its effects on muscle weakness.
Virginia Tech researchers are developing a new algorithm to predict the effects of novel gene mutations in living cells. They will apply this framework to models of cell growth and division in budding yeast, paving the way for faster drug development and improved cellular understanding.
A study published in Nature Communications reveals that eleven seal species narrowly escaped extinction, with most surviving strong population declines. However, four species, including the northern elephant seal and Mediterranean monk seal, suffered severe genetic loss due to overhunting.
A recent study led by University of Illinois social work professor Rachel Garthe found that parents' conflict-handling views play a significant role in shaping their children's behavior. The study surveyed over 1,000 sixth-, seventh- and eighth-grade students about their parents' views on handling conflicts. Results show that students ...
A simulation by researchers at the University of Michigan and others revealed that shockwaves can create loops in iron, which can strengthen or weaken steel depending on their placement. The discovery could help engineers design better radiation-resistant steel for reactors and potentially lead to stronger steel overall.
A new website aims to change the equation on death and trauma from firearms among young people by sharing what's known about guns and people under age 19. The site offers a trove of data and training for health care providers, researchers, and others to tackle the prevention of youth firearm injuries as a public health issue.
Researchers found that communal-reared males were more competitive towards unrelated males and displayed higher exploratory tendencies. These traits are advantageous in a high-density population or when dispersing from the natal territory.
Scientists at John Innes Centre and University of Queensland have improved space-inspired speed breeding technique to breed disease-resistant, climate-resilient crops. By using enhanced LED lighting and day-long regimes, they can grow six generations of wheat per year, compared to two generations using traditional breeding methods.
Researchers developed a new method to analyze cell membrane proteins directly, enabling new discoveries on protein function and behavior. This breakthrough could lead to better understanding of diseases such as cancer, metabolic disorders, and heart disease.
Tropical Cyclone Gaja made landfall along southeastern India's coast as it passed overhead the NASA Aqua satellite, providing temperature information. The AIRS instrument detected coldest cloud top temperatures of minus 63 degrees Fahrenheit near the center, indicating a storm capable of heavy rainfall
A new study reveals that cells decide when to divide based on their internal clocks, with the time of day having a stronger influence than previously thought. The circadian clock continuously influences cell division throughout the day and night, fine-tuning the process by decreasing or accelerating division at different times.
Research shows secondhand marijuana smoke can worsen asthma symptoms in children with cannabis allergies, even without direct exposure. After removing cannabis from the home, asthma symptoms improved significantly.
A new study has found a significant association between long-term exposure to road traffic noise and the risk of obesity. The research, published in Environment International, involved 3796 adults who took part in the Swiss SAPALDIA cohort study and had attended at least two follow-up visits between 2001 and 2011.
A recent study by Kansas State University found that only a small percentage of horticultural businesses are selling live plants online through platforms like Amazon. The study highlights the challenges faced by these businesses, including strict seller requirements and cost-prohibitive fees.
A recent study published at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting found that epinephrine auto injectors (EAIs) can still function properly even if they are unintentionally frozen. Researchers tested 104 devices and found no significant difference in weight changes before and after freezing.
Scientists in EMBL's De Renzis group use optogenetics to steer the shape transitions of embryonic tissues, controlling a crucial step in development. This technique allows them to inhibit abnormalities and provide new insights into tissue invagination.
Researchers from the University of Tokyo developed an AI-powered simulation that accurately models earthquake physics in urban centers, achieving a fourfold increase in speed. The new code adapts to precision needs and reduces computational power, enabling more efficient disaster response.
Scientists studied copper/gold and iron/palladium thin film reactions upon heating, enabling improved material properties for microelectronics. The research helps identify features of these systems for designing devices.
A study by researchers at Linköping University found that human pharmaceuticals altering serotonin levels change cricket activity and aggression. Crickets exposed to these drugs showed decreased activity and aggression compared to those with no exposure.
Researchers found DNA translocase Mfd accelerates mutations in bacteria, promoting antibiotic resistance. A new class of anti-evolution drugs targeting Mfd could complement existing antimicrobials and address the growing antimicrobial resistance crisis.
Researchers at Purdue University have developed a shoe insole that gradually releases oxygen to aid healing of diabetic foot ulcers. The insole can be customized to fit individual wound sites and is designed to improve mobility for patients with diabetes, who are at risk of losing toes or limbs if left untreated.
Engineers at the University of Michigan developed a method to make arrays of nanofibers that can be sticky, repellant, insulating or light emitting. The discovery uses liquid crystals to guide the growth of curved fibers with well-defined lengths and diameters.
The Chemical Weapons Convention comprehensively bans development, production, and use of chemical weapons worldwide. The OPCW must address scientific issues to prevent re-emergence, particularly regarding toxic 'non-lethal' or 'incapacitating' chemicals.
Researchers at Case Western Reserve University are developing a new system that uses changes in vibrations, sound, and electrical fields to improve energy consumption and monitor occupants' movements. The system has the potential to provide energy savings, track structural integrity, and enhance building safety.
Ben-Gurion University researchers develop process using hydrothermal carbonization to heat raw solid human waste, converting it into hydrochar: a safe, reusable biomass fuel. The hydrochar can be used for household heating and cooking, while the liquid byproduct serves as fertilizer.
A team of chemists has identified key enzymes in the metabolism of staphylococci, which could be targeted to starve bacteria and develop new antibiotics. The researchers used a novel methodology to isolate and analyze these enzymes, discovering previously unknown targets for new antibiotic development.
Researchers have found that the regions in the Earth's magnetosphere that energize the polar aurora are remarkably calm and nonturbulent. The study revealed intense electron jets associated with magnetic reconnection, which dump energy into Earth's atmosphere, exciting auroras.
Researchers have identified Toll-like receptor 3 as a new target for treating pulmonary hypertension by increasing its levels through high-dose RNA stimulation, potentially reducing inflammation and cell death in the lungs.
Researchers identify non-arthritis conditions causing joint pain and stiffness, emphasizing the importance of accurate diagnosis through imaging techniques.
Biomechanical forces play a key role in the development of joint inflammation and erosions in chronic inflammatory rheumatic diseases. The study identifies hot spots in the musculoskeletal system where mechanical loading leads to increased inflammation and tissue damage.
A study analyzing Twitter data from over 246,000 users found that social media usage largely reflects daily work schedules and school calendars. The data show a daily slowdown in tweets at night, with weekend usage shifting later than weekdays.
Researchers from UCL and University of Reading studied rapidly evolving aurora to understand energy release physics. They mapped back to where instabilities occur in space, gaining valuable physical clues.
Researchers found that a low-gluten, fibre-rich diet changes the community of gut bacteria and decreases gastrointestinal discomfort such as bloating. The study suggests that dietary fibres, not the absence of gluten alone, are the primary cause of these changes.
Researchers agree that an overall healthy diet is key, with a focus on quality over specific ratios. They identified areas of agreement and disagreement, including questions about carbohydrate-to-fat ratios and optimal fat intake.
Researchers at the Norwegian University of Science and Technology suggest that prioritizing fundamental human needs over economic growth could make it easier to reduce carbon emissions. They found that meeting subsistence and protection needs takes half of the global carbon budget, while leisure and identity take most of the other half.
A study by the Julius Kühn Institute and BfR found antimicrobial-resistant bacteria with multiple transferable resistance genes on fresh produce, including mixed salads, arugula, and cilantro. Consumers can minimize risk by washing raw vegetables thoroughly and considering heat treatment for immunocompromised individuals.
Researchers at Colorado State University have created a new carbon-carbon bond reaction using phosphorus to stitch together molecular rings called pyridines. This reaction could fling open an underexplored wing of biologically relevant chemistry, allowing for the discovery of new drugs.