A new X-ray laser method solves the phase problem for solution scattering, allowing scientists to visualize molecular structures in detail. This improvement will enable researchers to study viruses and other biological molecules more effectively, providing critical information about their internal density variations.
Scientists are working on novel solid state electrolytes to enhance battery energy density and reduce weight. Improved non-flammable and low-cost electrolytes have great potential for lithium metal technology, resulting in increased energy density and lighter batteries.
Researchers at UC Davis identified SynDIG4 protein as a crucial regulator of synaptic plasticity, enabling the formation and consolidation of new memories. The discovery sheds light on the molecular mechanisms underlying memory formation and could lead to novel therapeutic strategies for cognitive disorders.
Researchers used open-source software and genetic analysis to identify the male brown bear that killed a female and her two cubs in the Italian Alps. The study provides new insights into infanticide in small populations, highlighting its impact on species conservation.
Researchers have discovered 50 new gene regions increasing schizophrenia risk, including genes previously associated with intellectual disability and autism. These findings shed light on the disorder's complex genetics, suggesting subtle genetic variants can contribute to its development.
Scientists have discovered a way to control the flow of terahertz photons using ordinary computer chips, which could lead to faster computers and higher bandwidth communications. The method uses a 'coyote time' effect, where the molecule doesn't know its energy after the first photon hits, allowing for more efficient switching.
A food insecurity screening at pediatrician's offices was found to be effective but struggled with referrals due to fear of Child Protective Services and complicated processes. The study recommends better communication and connecting families with immediate resources to alleviate social stigma and improve outcomes.
Researchers will co-design hardware and software to realize quantum computing's potential more rapidly, focusing on efficient algorithms and tools for programming and education. The collaboration aims to create a community of academic and industry partners to drive progress in the field.
Researchers from Arizona State University reveal a hidden secret of the immortality enzyme telomerase, which holds promise for reversing cellular aging and extending human lifespan. Understanding the enzyme's mechanism may lead to effective anti-aging therapeutics.
A landmark study reveals that maternal immune system activation can shape brain development in babies, with elevated IL-6 and CRP levels correlating with changes in the salience network. The study found significant effects on infant brain function and development into toddlerhood.
A signaling protein called Daple, normally a tumor suppressor, can be manipulated by growth factors to become a driver of malignant growth and metastasis in cancer cells. This discovery highlights the complexity of crosstalk between major signals that drive cancers.
A study of US hospital inpatient discharges from 1993 to 2014 found a decrease in red blood cell and plasma transfusions between 2011 and 2014. This trend may be attributed to the implementation of restrictive transfusion practices aimed at improving patient outcomes and conserving blood.
A study using landscape genetics identified a decline in the endangered maple Acer miyabei's population due to habitat loss and fragmentation. The research highlights the importance of preserving forests along rivers and surrounding them to maintain gene flow, ensuring the long-term survival of this unique species.
Scientists have identified progenitor cells within the human pancreas that can be stimulated to develop into glucose-responsive beta cells. These findings open the door to developing regenerative cell therapies for those living with type 1 diabetes.
The Osher Collaborative for Integrative Medicine has launched a new quarterly column in JACM, discussing strategies to advance health justice through integrative medicine principles. The inaugural column highlights the need to address bias and discrimination in intrapersonal attitudes and behaviors.
Researchers at the University of Illinois used a combination of traditional kick-seining and environmental DNA (eDNA) techniques to study the rare Faxonius eupunctus crayfish. They found the species most abundant in the middle part of its 30-mile range, with up to 35,000 cubic feet of water flowing by each second.
Massive data analysis reveals that seasonal flu outbreaks originate in the southern and southeastern US, moving northward. The models incorporate health claims, weather, geography, and Twitter data to track the spread of influenza.
Researchers applied quantum machine learning to a real-world biological problem, predicting the strength of binding sites for transcription factors. The study demonstrated the potential of quantum computing for biology, with results consistent with current understanding of gene regulation.
Researchers at CU Anschutz Medical Campus found that shared decision-making can lead to better choices in high-stakes treatments. The study used patient decision aids to improve understanding and values-choice agreement, leading to more informed decisions.
Recent studies suggest that the Hawaiian hotspot moved southward at a rate of several tens of kilometers per million years. This new evidence contradicts the long-held assumption that hotspots are stationary and supports a dynamic Earth model.
The University of Houston has been awarded a $2.8 million grant to fund a teacher graduate program focused on STEM education. The program aims to prepare middle and high school teachers from underrepresented communities to lead STEM instruction and address disparities in education.
A Rice University-led team has been awarded $10 million by the NSF to create wearable and point-of-care microscopes that can monitor nearly 100 health conditions without invasive procedures. The technology aims to provide real-time, non-invasive imaging of tissues using on-chip illumination and sensing.
Researchers from UC3M and IMDEA Networks present several European research projects related to 5G technology, including 5G-Coral, 5G-Crosshaul, and 5G-Transformer. These projects aim to develop advanced 5G networks with improved efficiency and scalability.
The study found that wind and solar resources have natural variability, making it challenging to generate all electricity from these sources. Reliable electricity generation with 80% solar and wind requires a continent-scale transmission grid with at least 12 hours of storage.
Researchers at Carnegie Mellon University are part of a $10 million program to develop a new type of camera that can peer deep beneath the skin to diagnose and monitor various health conditions. The camera uses computational scatterography to make sense of scattered light, enabling noninvasive bio-optical imaging at a cellular scale.
Exertional heat stroke is a life-threatening condition in athletes that requires immediate cooling to prevent critical cell damage. The recommended treatment protocol 'cool first, transport second' prioritizes rapid cooling of the body to less than 104.5 degrees F within 30 minutes.
A NYU study found that states with robust tobacco control policies have fewer cigarette users and e-cigarette users, with variations in e-cigarette use by region and state. The study suggests that existing state-level tobacco control measures likely influence e-cigarette use.
A team of MSU scientists developed a method to create two beams of entangled photons, measuring the delay between them. They achieved a narrow peak in the sum frequency signal with a width of 90 femtoseconds, setting a new record for entanglement correlation precision.
Researchers found that bonobo gestures overlap extensively in meaning with those of chimpanzees, sharing up to 33 gesture types. This similarity may indicate an inherited trait or shared ancestral behavior.
A study investigated tau phosphorylation-related targets for Alzheimer's disease treatment, focusing on four kinases and one phosphatase. The model suggests the role of each enzyme in AD pathogenesis and identifies potential targets for therapy. This work builds upon InSysBio's quantitative systems pharmacology (QSP) modeling approach.
African Salmonella's deadly epidemic is caused by a specific genetic change, known as a SNP, which helps the bacteria survive in the human bloodstream. The discovery could lead to new insights into other pathogens and pave the way for a vaccine against this devastating infection.
Researchers have discovered that bonobo and chimpanzee gestures share multiple meanings, with many gestures having similar functions across the two species. The study, published in PLOS Biology, defines the meaning of each bonobo gesture by analyzing reactions and satisfaction levels.
A new study creates a functional map of how the hawkmoth smells, tracing the process from the antennae to specific areas in the brain. The researchers mapped how the moth distinguishes between odors to find a safe place to eat or to lay eggs.
Researchers developed machine learning software that allows computers to learn the quantum state of complex systems based on experimental observations. This approach enables faster tomography for quantum states and has implications for testing quantum computers with many qubits.
New research by Northeastern University scientists isolates pigment granules from squid skin to create ultra-thin films with rich colors. These materials could be used for adaptive coloration and camouflage applications.
Two landmark studies by Vanderbilt researchers show significant improvement in patient outcomes using balanced fluids instead of saline for intravenous therapy, leading to a decline in saline use at the hospital. The studies found a 1 percent lower incidence of serious kidney problems or death in patients receiving balanced fluids, res...
A new study by Ohio State University researchers found that psychedelic mushrooms developed psilocybin to interfere with insect neurotransmitters, lowering the chances of being eaten. This evolutionary explanation could guide medical science in finding novel treatments for neurological disorders.
A study found that military personnel receive extensive civilian mental health services due to inadequate military services. The most common reasons for seeking help were insufficient services, fear of reprisal, and mistrust of command.
Researchers at ETH Zurich have made a groundbreaking discovery that protein amyloids can self-replicate, challenging the long-held RNA hypothesis as the origin of life. The findings suggest that early life forms may have used amyloids as information carriers and catalytic units.
Researchers successfully crafted a metasurface-based lens atop a Micro-Electro-Mechanical System (MEMS) platform, combining the best features of both technologies while reducing size. The device measures 900 microns in diameter and 10 microns in thickness, advancing LIDAR systems used to guide self-driving cars.
Regular monitoring for cervical intra-epithelial neoplasia grade 2 (CIN2) is justified, as many moderate lesions regress spontaneously, especially in women under 30. After two years of active surveillance, half of the lesions have regressed, while one third persist and just over a fifth progress to CIN3 or worse.
Dr. Clapp's research aims to better understand the factors affecting unanticipated NICU admissions and their relation to obstetric care quality. The study will use data from multiple sources, including the Consortium for Safe Labor trial and national birth certificate data.
Loss of protein PHLDA1 is sufficient for development of drug resistance to targeted therapy in endometrial and HER2-positive breast cancer cells. Rescuing PHLDA1 expression re-sensitises cancer cells to RTK inhibitor.
Researchers at Washington University in St. Louis have developed a method enabling effective insertion of large molecules into cells using acoustic shear poration and electrophoresis. The approach has achieved greater than 75 percent delivery efficiency of macromolecules, including DNA insertion, which is significantly more challenging.
A 20-minute video was created to help child daycare providers prepare for disasters, addressing concerns of unpreparedness. The video, developed through a collaboration between several stakeholders, provides key points in disaster planning for daycare providers.
A team of researchers has developed a technique that can perform both 3D super-resolution microscopy and fast 3D phase imaging in a single instrument, enabling high-time resolution visualization of living cells. This new platform, called PRISM, allows for direct visualization and analysis of subcellular structures without labeling.
A study published in Leukemia found that starting mixed phenotype acute leukemia (MPAL) treatment with a less-toxic regimen is linked to better remission rates and long-term survival. Patients treated initially with ALL therapy were three to five times more likely to achieve complete remission than those receiving AML therapy.
Researchers developed two models to optimize food bank operations, accounting for uncertainty in capacity and demand. The models aim to distribute food efficiently and equitably while minimizing waste.
Researchers have reported significant advancements in measuring blood flow velocity in deep tissues using a handheld ultrasound probe. The new technique, known as photoacoustic flowmetry, has the potential to bring diagnostic capabilities closer to clinical use.
The study analyzed the influence of belt structure on tire vibration and noise, revealing that optimized belt structures can reduce vibration noise by 7.55 dB. The findings provide a theoretical basis for developing low-noise tires in the future.
Researchers use GIRI to deconstruct rock samples and create three-dimensional digital versions of fossils, allowing for accurate analysis without human bias. This technology has enabled scientists to reevaluate the role of ancient organisms in shaping early ecosystems.
A study by researchers at the University of Michigan found that more nurse practitioners practice in lower-income areas with low life expectancy. This trend may offset a shortage of doctors in high-need areas.
The Association for Molecular Pathology (AMP) has published consensus-based recommendations for clinical CYP2C19 genotyping allele selection. The guidelines aim to standardize testing across laboratories and improve concordance, enabling better patient care.
Prof Alba-Tercedor collaborated with BUF to create high-resolution microtomography images of tropical longhorn beetle species and darkling beetle Zophobas morio, used in the film's photorealistic models. The results demonstrate microtomography's value for reconstructing tiny animals' microscopic structural details.
Scientists at UCI, Caltech, and Carnegie Institution for Science found that US can reliably meet 80% of electricity demand with solar and wind power generation. However, meeting 100% demand would require significant investment in energy storage and transmission capabilities to overcome seasonal and weather variabilities.
Researchers from the Max Planck Institute for Chemical Ecology found that activity in specific brain areas correlates with different behaviors in female Manduca sexta. The study identified a functional atlas of the antennal lobe, which is linked to feeding behavior, whereas other areas are related to egg-laying.
Researchers at KAUST found that high salinity can protect corals from heat stress by increasing the levels of antioxidant floridoside. This compound helps regulate osmotic pressure and prevent severe bleaching in coral model organism Aiptasia.
This special issue of the Journal of Pediatric Rehabilitation Medicine presents significant contributions from the Third World Congress on Spina Bifida Research and Care, covering topics such as regenerative medicine, genetics, trauma care, and self-management. The goal is to improve healthcare for individuals with spina bifida, includ...
Researchers have found that wearable activity data can predict various markers of risk for cardiovascular diseases such as obesity, high blood pressure, and high blood sugar. The study also identified active individuals at increased risk of having enlarged hearts, a condition commonly thought only to affect competitive athletes.
Researchers at USC Michelson Center successfully utilize a new metal detection technique for studying cancer cells. By imaging metal-tagged antibodies on biopsies from a patient with metastatic prostate cancer, scientists can identify and characterize cancer cells in a blood sample after it is placed on a slide.