Researchers studied dengue virus fusion peptide structures, revealing a hydrophobic region and polar 'collar' crucial for cell membrane fusion. This review aims to expand knowledge on the mechanism of virus infection, potentially leading to new inhibition methods.
SourceBentham Science Publishers·JournalProtein and Peptide Letters·DateJan 13, 2019
Researchers at the University of Montpellier develop a clean conversion process for fused bicycles into spirocycles using activated 2,5-diketopiperazines as starting materials. The method demonstrates the versatility of ring contraction reactions and has potential applications in various fields.
SourceBentham Science Publishers·JournalLetters in Organic Chemistry·DateJan 13, 2019
American University researchers identify Tpl2 gene's role in squamous cell carcinoma, revealing potential therapeutic target for advanced cancers. The study shows that blocking the MET receptor reduces tumors by 60%, offering new hope for treatments.
SourceAmerican University·JournalOncogenesis·DateJan 13, 2019