A new longitudinal analysis of 254 COVID-19 patients reveals that IgA and IgM antibodies disappear quickly during convalescence, while IgG antibodies persist but decline slowly. The study's findings may impact seroprevalence studies and raise questions about vaccination durability.
The German National Academy of Sciences Leopoldina has published a report on the future of ageing and life course research in Germany, outlining recommendations for advancing research on ageing. The report highlights challenges arising from the COVID-19 pandemic and compares Germany's performance to other countries.
The study showed that the combination of chemotherapy and blinatumomab resulted in increased survival rates and achieved a high rate of MRD negativity for patients with Ph-negative B-cell ALL. This treatment approach has the potential to improve long-term outcomes for these patients.
Researchers at the University of Bath found that children learn about evolution more effectively when engaged through stories read by the teacher, rather than through doing tasks. The story-based approach combined with abstract examples was the most effective in improving pupils' understanding of evolutionary concepts.
A new study identifies a method that detects COVID-19 in wastewater samples and tracks infection trends. The test uses genetic material from SARS-COV-2 RNA, which correlates with community COVID-19 infections.
A novel harmonization method was used to develop a generalizable brain network marker for major depressive disorder (MDD), based on resting-state fMRI data. The marker achieved approximately 70% generalization accuracy for an independent validation dataset, demonstrating its potential for clinical applications.
Researchers at Tohoku University studied Zinc-Oxide crystals' IQE in both light-emitting and non-light-emitting processes. The study found that deceleration of the non-light-emitting process, due to saturation of NRCs, dominated IQE increase.
Researchers at King Abdullah University of Science & Technology created an ultrathin porous membrane using molecular building blocks to separate molecules of different sizes and shapes. The membrane outperformed traditional membranes in filtering organic solvents, with high selectivity and durability.
A subcutaneous injection of teclistamab elicits responses in 74% of patients with relapsed/refractory multiple myeloma, offering a promising treatment option for patients with poor prognoses. The study's results suggest that teclistamab takes a similar approach to cellular therapies but is more convenient and faster to administer.
The combination of venetoclax with chemotherapy improves outcomes for patients with AML and MDS, with a promising overall response rate and acceptable safety profile. Venetoclax also demonstrates efficacy in treating high-risk MDS when combined with azacitidine.
Researchers from RUDN University have developed a new method to analyze cytokines in nasal swabs to predict disease flow and prevent complications in asthma patients with accompanying diseases. The study found that monitoring specific cytokine profiles can help identify dangerous tendencies and allow for timely intervention.
A recent study by Dana-Farber Cancer Institute scientists has found that clonal hematopoiesis can confer a health benefit in the setting of allogeneic stem cell or bone marrow transplants. Patients who received transplants from older donors with CH had a lower risk of relapse and longer survival compared to those without CH.
A recent study presented at the 2020 ASH meeting demonstrated that Gazelle's integrated anemia-SCD test has a high sensitivity and specificity for detecting anemia, with over 92.3% accuracy. The test is expected to be available in mid-2021 and has the potential to improve disease management in low-resource settings.
Axicabtagene ciloleucel (axi-cel) achieved undetectable cancer levels in nearly 80% of patients, and durable responses in most participants. The therapy demonstrated improved response rates for follicular lymphoma compared to marginal zone lymphoma.
The Inouye Solar Telescope has released its first image of a sunspot, revealing striking details of the sunspot's structure. The image achieves a spatial resolution about 2.5 times higher than ever previously achieved, showing magnetic fields as small as 20 kilometers on the surface of the Sun.
Researchers at the University of Rochester used magnetism to determine when carbonaceous chondrite asteroids arrived in the inner solar system. This discovery provides insights into the evolution of the solar system and the origin of Earth's habitability. The study also offers data for the discovery of new exoplanets.
Scientists track animal activity levels using new satellite technology, providing insights into their responses to environmental changes. The study's findings open up new research opportunities for understanding climate change impacts on marine species.
A University of Massachusetts Amherst physicist found that opening the front window on the right side and the rear window on the left side can create an air current barrier, reducing airborne pathogen transmission in cars. This measure can help lower the pathogen load in confined car spaces.
Computational fluid dynamics simulations suggest driving with all windows down and the passenger seated as far possible from driver reduces transmission of simulated infectious droplets. The opposite scenario, all four windows up, was found to be the riskiest due to highest airflow velocity.
Researchers discover that reactive oxygen molecules control cellular processes important for brain adaptation in mice. Free radicals are necessary for healthy aging and neuroplasticity, contradicting previous harmful views.
A new system developed by Arizona State University researchers measures solar panel performance in outdoor settings, enabling real-time measurements and detailed diagnostics. The goal is to increase efficiency and lifespans of photovoltaic systems, supporting the development of universally effective solar cells and systems.
Iron deficiency affects two billion people, causing anaemia and serious health consequences. The new guidance outlines evidence-based approaches to diagnose and manage iron deficiency, leading to improved health outcomes.
The study uncovered essential properties of ions in metal halide perovskites, which have a negative effect on the efficiency and stability of perovskite solar cells. The researchers found that all ionic defects meet the Meyer-Neldel rule, revealing fundamental information about ion hopping processes in perovskites.
A study published in Radiology found that digital breast tomosynthesis (DBT) improved cancer detection and reduced false negative rates compared to digital mammography. DBT also showed advantages in imaging women with dense breasts, leading to lower recall rates and more effective cancer screening.
A new CRISPR-based test for COVID-19 can provide accurate results in under 30 minutes using a smartphone camera, enabling faster and more accessible testing. The test measures viral load, helping healthcare professionals estimate the stage of infection and predict recovery.
Lung tissue analysis reveals MBD2 as a promising target for treating lung fibrosis, which is characterized by overexpression of this epigenetic regulator in areas occupied by macrophages. Inhibiting MBD2 may prove to be a safe way to treat the chronic and irreversible disease.
Biologists from RUDN University identified polymorphisms in six genes that determine flaxseed oil's fatty acid composition and shelf life. The study found specific gene variations that extend the shelf life of flaxseed oil, improving genetic selection for new flax breeds.
Researchers from Incheon National University develop a novel catalyst with a protective carbon shell that selectively prevents undesired reactions in methanol fuel cells. The study showcases improved performance and stability over commercial platinum catalysts.
Researchers have discovered hidden subcompartments within peroxisomes, long thought to be simple granular matrices. These subcompartments may play a crucial role in the metabolism of fatty molecules and could hold key to understanding diseases like obesity and neurodegeneration.
Researchers review factors contributing to disconnect between created and utilized marketing data, highlighting overlooked sources for growth opportunities. The study explores the potential of biometric and social network data to support customer acquisition, relationship development, and retention.
Researchers successfully identified all fish species in the ponds, demonstrating high accuracy of non-invasive eDNA approach. Strong positive correlations were found between eDNA quantity and actual fish biomass and abundance, paving the way for step change in future species monitoring programmes.
Researchers at Tokyo Medical and Dental University have developed a cross-linker for dental cement that breaks down under UV light, making treatments easier to reverse. This breakthrough enables non-permanent adhesion to the tooth surface without damaging enamel.
Researchers at BIDMC identified the role of antibodies and T cells in protecting against COVID-19, finding that low antibody levels can still provide protection when combined with a strong T cell response. The study's findings have important implications for vaccine development and public health strategies.
Researchers at Incheon National University developed a novel control strategy to optimize current delivery in multi-Tx wireless charging, enabling real-time adjustment and maximizing efficiency. This breakthrough can improve the performance of robots and electric cars by reducing battery size and weight.
Researchers identified coral GSDME as a pyroptosis-inducing protein in reef-building corals, revealing its role in pathogen-induced coral death. Activation of coral GSDME triggers rapid cell swelling and cytoplasmic content release, leading to necrotic tissue damage.
The quality of publications from universities participating in Project 5-100 has improved significantly, with collective publications tripling over three years. Researchers have also increased collaboration with each other and international organizations.
A combined research team from Universities of Portsmouth and Bournemouth has shown that the National Early Warning Score (NEWS) can predict adverse clinical outcomes in patients with Covid-19. The study confirms the effectiveness of NEWS without requiring new techniques, supporting NHS staff during the pandemic.
Researchers have developed an acoustofluidic process that can isolate sperm with normal head morphology and high DNA integrity from raw semen samples. The device selects over 60,000 high-quality sperm in under 50 minutes, providing a clinically-relevant number for IVF and ICSI.
A study by NYU Langone Health found that once hospitalized, Black patients with COVID-19 have better outcomes than White patients. The research controlled for comorbid conditions and neighborhood income.
Sushil Jajodia and Massimiliano Albanese are supporting a $225,000 project on cyber knowledge management with secure information transfer for weapons systems. They provide expertise and review services to Texas-based company Knowledge Based Systems, Inc.
A recent study by the German Centre for Integrative Biodiversity Research (iDiv) has found that living near areas with high biological diversity increases life satisfaction among Europeans. The research, which analyzed data from over 26,000 adults across 26 European countries, discovered that experiencing numerous different bird specie...
The Stingray nebula has faded precipitously over the past two decades due to a temperature drop in its central star, SAO 244567. Researchers have observed unprecedented changes in the nebula's structure and brightness, with the oxygen emission dropping by nearly 1,000 times between 1996 and 2016.
This observational study examines racial/ethnic disparities in COVID-19 outcomes among patients in NYC, revealing significant differences in hospitalization and mortality rates. The study also assesses the association between disparities and coexisting medical conditions and neighborhood characteristics.
Researchers from RUDN University created a wound-healing gel using the metabolic product L-lysine-oxidase produced by Trichoderma fungi. The gel showed advanced wound-healing properties, with carbopol-based gel demonstrating the best results in treating wounds.
Researchers at NTNU have used CRISPR to strengthen muscle cells and replicate positive exercise effects in heart-diseased rats. This gene therapy approach holds promise for treating heart disease without the need for daily medication.
The use of immunity passports is a topic of debate, as science is unsure about the duration of immunity and potential risks of reinfection. Experts argue that immunity passports could limit fundamental rights, such as freedom of movement, but also propose respecting the right to move freely for those who cannot spread COVID-19.
Researchers at Kyushu University have developed a new material system that can directly convert visible light into ultraviolet light with an efficiency of up to 20.5%, doubling previous records. The system is promising for harnessing ambient light to drive applications requiring high-energy ultraviolet light.
A new study by LSU Health found that neighborhoods with higher levels of deprivation have a significantly higher risk of COVID-19 cases. The researchers used the Area Deprivation Index to examine the relationship between neighborhood poverty, education, and housing conditions on COVID-19 transmission.
The Occupational Depression Inventory (ODI) is a new tool measuring work-attributed depressive symptoms. Researchers found that 7.6% of participants met criteria for job-ascribed depression, highlighting the need for effective treatment and prevention strategies.
A team from UNIGE used a specially developed video game to investigate the emergence of emotions, confirming that brain components respond in parallel distributed throughout the brain. The results show transient synchronisation generating an emotional state, involving areas like the somatosensory and motor pathways.
A new machine learning approach offers important insights into catalysis by providing a tool to design efficient catalytic processes. The Bayeschem model explains how catalysts interact with different intermediates and determines the optimal bond strengths.
Researchers found COVID-19 infected individuals with type 1 and type 2 diabetes are three times more likely to have severe illness or require hospitalization compared to those without diabetes. The study urges policymakers to prioritize these individuals for COVID-19 vaccination.
Research team led by HPSTAR discovered that isotope effect can significantly suppress lattice distortion in hybrid perovskites, leading to enhanced photoluminescence and structural robustness. This breakthrough suggests a new path for designing more stable photovoltaic materials with superior performance.
A large prospective study found a link between kidney injuries and cognitive impairment in children with diabetic ketoacidosis. The study suggests that the presence of acute kidney injury is associated with lower IQ scores and subtle cognitive impairment.
A $2.1 million federal grant will enhance clinical trial access in five areas, including care before birth and obesity, with the goal of improving health outcomes for all Louisiana children and potentially slowing or preventing chronic diseases like asthma.
Researchers have discovered a genetic connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), with the same huntingtin mutation associated with Huntington's disease. The study opens up possibilities for gene therapy targeting this mutation, which could lead to personalized medicine.
The Lancet Global Countdown on Health and Climate Change highlights the devastating impact of climate change on human health, with key trends worsening unless urgent action is taken. Experts from institutions worldwide, including Columbia University Mailman School of Public Health, contribute to the report's findings.
Scientists at La Jolla Institute for Immunology have found elongated neutrophil-derived structures (ENDS) in the blood of septic patients, which break off from immune cells and change shape as they course through the body. ENDS are 100-fold more detectable in sepsis patients than healthy individuals.
Researchers confirm flat band behavior in germanium's 2D 'bitriangular' lattice, a structure with potential for exotic states of matter like ferromagnetism and superconductivity. The discovery confirms earlier theoretical predictions and opens up new possibilities for materials design.
In 2D simulations, researchers found that the pseudo-turbulence relationship changes within larger-scale flows in less viscous fluids. The team discovered an inverse energy cascade and a different mathematical relationship between flow energy and frequency.