Researchers found that high-protein diets increased the survival of infected caterpillars by causing osmotic stress, which slows down bacterial growth. This mechanism may offer a new avenue for understanding how diet affects parasitic blood infections in humans.
Researchers investigate vulnerability of smart city water and energy systems to cyber attacks, which can cause blackouts and damage. The study aims to develop detection methodologies to counteract such criminal acts using mathematical attack models and big data analytics-based methods.
A new study found that probiotics with top-performing Lactobacillus strains can improve vaginal health and reduce the risk of bacterial vaginosis, a disruption in the optimal microbiota. The research suggests that these strains could lead to better treatment options for this condition.
Researchers have developed a new method called redHUMAN to simplify genome-scale metabolic models for analyzing human metabolism. This approach reduces the complexity of human genome-scale models by focusing on specific parts of metabolism while minimizing information loss.
Researchers developed a single-molecule orientation imaging approach to study amyloid proteins, revealing nanoscale differences in their structures. The method provides insights into the fundamental biological mechanisms of disease, potentially contributing to the development of effective therapeutics.
Using simulated silicon neurons, researchers found that energy constraints can lead to a dynamic, at-a-distance communication protocol more robust and energy-efficient than traditional computer processors. This protocol enables computing on a secondary network of spikes, allowing for efficient communication and processing.
A new study by Dr. Thomas D. Carr finds that the size and weight of Tyrannosaurus rex do not determine its age, contrary to long-held assumptions. The research reveals a high-resolution growth series for T-Rex, which shows that even small juveniles had powerful skulls and teeth, making them just as deadly as adults.
Researchers introduce a novel approach using genetically engineered microbes with DNA barcodes to track food contamination and provenance. The system, called barcoded microbial spores (BMS), can persist on surfaces for months and transfer between objects, making it suitable for tracing supply chains.
BIOCAD presents results of clinical trial showing netakimab decreases disease activity and reduces skin manifestation of psoriatic arthritis through 24 weeks of therapy. The treatment was well-tolerated, with significant improvement in skin manifestations and quality of life.
A new study by Bocconi University researchers finds that the majority of phase III trial results are not significantly above threshold, contrary to previous findings. The researchers suggest that transparency and registration processes are key factors in maintaining trial integrity.
The 'Testbench' project enhances the quality of efficiency measurements for solar power storage systems, facilitating comparison and standardization. The goal is to improve reproducibility and confirm the results, ultimately benefiting operators and manufacturers in the growing market.
Researchers have discovered biochemical alterations in skin cells, urine, and cerebrospinal fluid of patients with Lesch-Nyhan disease. High levels of folic acid reversed these alterations in cell cultures, suggesting a possible treatment strategy.
A recent study published in Neurogastroenterology & Motility found that high-fat diets change the nutrient-sensing capacity of Enterochromaffin (EC) cells in mice, leading to increased serotonin levels and potential implications for obesity and type 2 diabetes
Researchers identify NELL2, a testicular protein that travels through the epididymis to mature sperm and enable fertilization. The discovery sheds light on male infertility and offers new avenues for diagnostic and therapeutic research.
A new UC Riverside study aims to identify the mechanisms by which the PTPN2 gene regulates immune interactions between macrophages and epithelial cells. The research could lead to fundamental insights into how loss-of-function mutations contribute to autoimmune diseases like IBD.
The study found that prescriptions for buprenorphine treatment increased significantly among adults, particularly those prescribed by primary care providers. However, access to treatment decreased among young adults and teens, primarily due to a decline in prescriptions from psychiatrists and addiction medicine specialists.
Researchers from the University of Houston have reported a structural supercapacitor electrode made from reduced graphene oxide and aramid nanofiber that is stronger and more versatile than conventional carbon-based electrodes. The new material offers promise for longer battery life and higher energy at a lighter weight.
Researchers have developed self-assembling biomimetic composites with unusual electrical properties. By breaking the rule of mixtures, these materials can exhibit different in-plane and out-of-plane conductivities.
Cristobal has the potential to generate heavy rainfall, with NASA's AIRS instrument revealing cold cloud top temperatures indicating strong storms. The storm is expected to produce extreme rainfall amounts through the end of the week, causing life-threatening flash floods and mudslides in affected areas.
A new study characterizes concussions in elementary school-age children, revealing common vision and balance issues that warrant consistent assessments at the initial healthcare visit. The findings emphasize the need for targeted interventions to improve outcomes, including school accommodations and vestibular or vision therapy.
Pediatric surgical patients presented with COVID-19 at three US children's hospitals. The study found a significant number of infected patients, emphasizing the need for infection control measures.
The OPTIMUSCLOUD system uses machine learning and data science principles to develop algorithms that optimize virtual machine selection and database management system options. This results in significant cost savings for cloud vendors and clients alike.
Researchers found that death is preceded by accumulation of reactive oxidative species (ROS) in the gut, which can be neutralized to prevent premature death. The study on fruit flies suggests a key role for the gut in causing death from sleep deprivation, and may inform future efforts to address its detrimental effects in humans.
A University of Central Florida researcher has developed a new display technology that mimics the colors of butterfly wings, creating ultra-high-definition screens with extremely low power consumption. The technology uses nanoscale structures to scatter and reflect light, producing more natural-looking images without harsh glare.
A new tool using 3D facial imaging and machine learning could help diagnose genetic syndromes more quickly and inexpensively. The prototype was created by a team of researchers from the University of California, San Francisco, and has been shown to accurately classify most subjects as either unaffected or having a syndrome.
A team of scientists has provided clarity into how new cells remember their identity after cell division. They found that many genes are activated immediately after cell division, acting in a cascade to send critical signals and allow the cell to 'wake up' from its cellular amnesia.
Researchers at Purdue University have developed a technique to analyze the energies of 'hot' electrons, which could lead to more efficient energy conversion in solar panels and other applications. The method uses a scanning tunneling microscope integrated with lasers and optical components.
A straightforward fabrication method has been introduced by researchers from Osaka University to improve the gas sensing performance of common ceramic coatings. The new method involves depositing a thin, porous titanium dioxide film onto a surface using spin coating, resulting in a significant increase in detection speed and accuracy.
A new study finds that preliminary criterion scores do not mitigate racial disparities in NIH grant awards, with black investigators receiving worse scores on all five criteria. The study reveals substantial funding gaps between black and white applicants, with black PIs award probability only 55% of their white counterparts.
Researchers at Aalto University have created an armour-plated superhydrophobic surface that can withstand sharp and blunt objects while maintaining its world-record effectiveness in repelling liquids. The surface features a honeycomb-like structure of tiny inverted pyramids, protecting the fragile chemical coating from damage.
A recent study found that N-BPs like alendronate are associated with a 24% lower risk of pneumonia and 35% lower risk of pneumonia mortality compared to no treatment. The results suggest that N-BP treatment may also protect against pneumonia, warranting further investigation into its potential for treating COVID-19 symptoms.
Researchers at the Technical University of Denmark have developed a new design for bridge girders that uses topology optimization to minimize steel use while maintaining strength. The design could lead to weight reductions of up to 28% and corresponding CO2 emissions savings of up to 20%.
The study found that total and non-HDL cholesterol levels are falling sharply in high-income countries, particularly those in North-western Europe, North America, and Australasia, while rising in low- and middle-income nations, especially in East and Southeast Asia. This shift has significant implications for global cardiovascular health.
Scientists at DGIST propose novel host structure called 'platelet ordered mesoporous silica' to trap lithium polysulfides and improve battery stability. The silica structure retains more sulfur, resulting in greater capacity retention and stability over 2000 cycles.
A genetic analysis of brook trout in Loyalsock Creek drainage reveals that fish are moving between tributaries, using the mainstem as a seasonal corridor. This finding contradicts previous research and suggests that conservation efforts should focus on larger streams and rivers to protect critical movement corridors.
A new study has found no link between recent cannabis use and an increased or decreased risk of ischemic stroke. Despite previous studies with conflicting results, researchers adjusted for various factors and found no association between marijuana use and stroke risk.
Researchers developed a new precision spray-coating method to create multilayer perovskite solar cells with better performance and stability. The technique allows for customizable device designs, enabling specific performance and stability requirements.
A team of European researchers used Hubble Space Telescope to study the early Universe, finding no evidence of Population III stars. The discovery suggests that galaxies must have formed much earlier than previously thought, supporting the idea that low-mass galaxies are responsible for reionisation.
A Princeton team has discovered a compound, SCH-79797, that can target both Gram-positive and Gram-negative bacteria without inducing resistance. This breakthrough could lead to the development of new, effective antibiotics against antibiotic-resistant superbugs like MRSA and Neisseria gonorrhoeae.
Scientists at CNIC discover a system providing cells with positional information about their location in developing organs. The study shows that malfunctioning of this system causes congenital malformations and may explain the effects of thalidomide, a drug inducing limb defects.
A new study from the University of Eastern Finland found that antiepileptic drug use is associated with a significantly higher risk of death among people with Alzheimer's disease. The increased mortality risk was observed even after controlling for comorbidities and other factors.
Researchers found that RSV manipulates two gene receptors in cells to gain entry and infect. The discovery sheds light on how the common respiratory syncytial virus breaks into cells, a key step in infection. Current treatment options are limited, but blocking the interaction of the virus with the receptor may prevent infection.
Researchers at Penn State created a brief animated video to educate people about the risks of antibiotics, finding it effective in convincing participants that antibiotic use can be risky. The study suggests that a video intervention could help increase public awareness and promote antibiotic stewardship.
Tropical Storm Cristobal generated large amounts of rainfall over Mexico's Yucatan and Central America. NASA analyzed cloud top temperatures using satellite data to assess the storm's strength.
Researchers found only 34% of mothers exclusively breastfed to six months due to milk shortages or breastfeeding difficulties. Mothers may need to supplement or stop if they experience problems.
Research found that patients with ARDS experience financial toxicity, leading to physical and emotional consequences. Long hospitalizations result in large medical bills, affecting patients' ability to recover and return to work.
Researchers found that double-sided solar panels combined with single-axis tracking technology are the most cost-effective solution, producing almost 35% more energy than traditional systems. This combination reduces electricity costs by an average of 16%.
A new study maps the world's terrestrial vertebrates and finds that human activity is impacting areas with large concentrations of evolutionarily distinct species. Regions like the Caribbean, Western Ghats of India, and Southeast Asia face unprecedented levels of devastation.
Available data indicate heavy metal levels in some Alaskan soils often exceed average US levels, with critical gaps in monitoring due to limited publicly available data. The study highlights the need for further sampling near human populations and in permafrost-heavy regions to clarify exposure risks.
A COVID-19 patient care approach has been developed to help hospitals safely care for patients, featuring dedicated units with risk zones and buddy systems for healthcare professionals. Key findings include adopting patient-centred practices, fostering a culture of safety, and standardizing procedures.
Research reveals that rivers play a crucial role in transporting burned carbon from wildfires and managed burning to oceans, where it can be stored for tens of millennia. The study estimates that 18 million tonnes of dissolved burned carbon are transported annually by rivers.
A new study by UC Santa Barbara researcher Douglas J. Kennett and collaborators found that maize had become a staple grain in the Americas 4,700 years ago, exceeding what is considered a staple grain. By 4,000 years ago, maize was persistently used as a staple, continuing through the Classic Maya period until today.
A study published in Oncotarget found that physical activity can modulate miRNAs involved in breast cancer progression, leading to reduced cancer cell viability. The researchers identified two specific miRNAs, miR-206 and anti-miR-30c, which showed promising results as non-invasive biomarkers for breast cancer prevention.
Tropical Cyclone Nisarga strengthened significantly before making landfall in west central India, according to NASA infrared data. The storm intensified from 40 knots to hurricane strength within 12 hours, with cloud top temperatures reaching as cold as minus 63 degrees Fahrenheit.
Researchers found that the loss of UBE2K enzyme silences key genes for neuronal differentiation, leading to impaired development of nerve cells. The study provides a potential link between epigenetic regulation and neurodevelopmental diseases.
Researchers develop nanoparticle-sized semiconductor laser generating coherent green light at room temperature, overcoming a significant technological hurdle. The tiny laser operates efficiently without external pressure or low temperatures.
Researchers at UC Santa Barbara developed a new approach to design LEDs that can extract and direct photons with high efficiency. By using metasurface concepts, they were able to confine electrons and holes in gallium nitride nanorods, allowing more light to escape the semiconductor structure.
A new study by the American Cancer Society finds that racial disparities in cancer mortality result in significant economic losses, with $3.2 billion in lost earnings avoided in 2015 if non-Hispanic black cancer deaths and earning rates had been equal to those of non-Hispanic white cancer patients. The study highlights the importance o...
A new study found that age does not necessarily disqualify older patients from breast cancer surgery, but serious adverse events are rare. Surgery can have a negative impact on quality of life and functional independence in older patients.
Researchers from ETH Zurich have deconstructed the complex mechanisms that control tissue repair and scar formation, focusing on a signal molecule called activin. The study reveals how activin affects cell interactions and extracellular matrix composition, promoting wound healing but also causing scarring.