A new RNA-sequencing method, PANDORA-seq, can detect modified small RNAs that were previously undetectable. The method employs a stepwise enzymatic treatment to remove key RNA modifications, uncovering a surprising small-RNA landscape dominated by tsRNAs and rRNA-derived small RNAs.
Near-poor Americans, just above the federal poverty level, face high medical bills and forgo essential health care due to a Medicaid eligibility cliff. Researchers propose solutions to fix this gap, including expanding supplemental coverage and simplifying the application process.
Researchers from Argonne National Laboratory have synthesized a stable borophane nanosheet with potential applications in nanoelectronics and quantum information technology. The material is stronger and more versatile than steel, making it a promising candidate for future devices.
Researchers have developed a safer, biodegradable alternative to conventional polyurethanes using fish waste. The new material, made from fish oil and amino acids, shows promising signs of breaking down in the environment.
Researchers investigate the ecological impacts of solar radiation modification (SRM) on Earth's ecosystems. The study predicts SRM could have complex and uneven effects on ecosystem functions and biodiversity. Climate scientists emphasize the need for continued decarbonization efforts alongside SRM research.
A recent study of over 2,000 companies found that those facing financial constraints can recoup significant amounts by modifying their tax strategies. The researchers discovered that these firms generated an average of 19% of their investment shortfall through tax planning, with some even receiving one-time benefits like R&D expenses.
Researchers develop a new bioprinting process using ultrashort peptides, overcoming challenges in cell survival and creating complex scaffolds that facilitate long-term cell growth. The technology enables the creation of tissue models for high-throughput drug screening and diagnosis.
Two studies from Indiana University and Regenstrief Institute found discrepancies between recorded POLST orders and current treatment preferences among nursing home residents. Regular review and update of these documents are crucial to ensure they reflect changing situations and patient wishes.
The Skoltech team used ultra-high resolution mass spectrometry to study the molecular composition of carbonaceous chondrites from Murchison and Allende meteorites. They discovered a wide diversity of chemical compounds and unexpected similarities between meteorites from different groups.
A recent study published in Health Affairs found that urgent care centers are associated with increased spending for lower-acuity visits across both emergency departments and urgent care centers. For every 37 urgent care visits, one fewer lower acuity ED visit occurs, but total costs increase rather than decrease.
A new analysis of 40 years of data found that winter snowmelt is increasing in all cold season months, affecting water resource planning and management. This shift in water delivery timing could also impact wildfire seasons and agricultural irrigation needs.
Researchers used simulations to determine optimal placement of a UVGI device to sterilize a space safely. They found that ceiling height and material reflectance had a major impact on efficiency and safety, recommending higher heights and low-reflectance materials.
Researchers identified a Goldilocks zone for raindrop size to determine which drops make it to the surface. This behavior helps model cloud cycles and predict exoplanet habitability.
A new method to predict lumber prices has been developed by a professor at Oregon State University, using readily accessible economic information. The study found that variables such as housing permits, inventory of homes, and mortgage rates can explain about 46.8% of log price variation.
The COVID-19 pandemic highlights the need for a public goods approach to essential medical services, as widespread vaccine nationalism threatens global herd immunity and equitable access. The US government is urged to invest in multilateral partnerships and global allocation strategies to increase vaccine supply and manufacturing.
New research reveals the permanent rise of oxygen in our atmosphere happened 100 million years after initial estimates. The discovery suggests fluctuations in atmospheric oxygen levels played a key role in extreme climate changes and extinction events.
A new study suggests removing additional tissue around the tumor cavity can reduce positive margins in patients with ductal carcinoma in situ (DCIS) by nearly 65%. Achieving clear margins is crucial in decreasing cancer recurrence, and this technique should be considered for DCIS patients.
A two-decade study of wild Soay sheep in Scotland reveals that telomere length is correlated with individual longevity. However, the effect of telomere length on mortality appears to be driven by genetic factors rather than environmental influences.
A study at Tel Aviv University reveals that fireflies produce strong ultrasonic sounds that may serve as a defense mechanism against bats. The sounds are undetectable to the fireflies themselves but can be heard by bats, potentially keeping them away from poisonous fireflies.
A UCF study suggests that masks and proper ventilation are key to reducing the airborne spread of COVID-19, potentially allowing more capacity in schools and businesses. The research found that aerosol transmission routes do not require six feet social distancing when masks are mandated.
A recent study by Syracuse University researchers found that EMS workers are three times more likely to experience mental health issues such as depression and posttraumatic stress disorder. Daily mental health symptoms can be reduced through recovery activities like exercising, socializing, and finding meaning in challenges.
A new study reveals that chronic ozone stress decreases crop yields in maize by 25%, while hybrid plants produce more chemicals to cope with the damage. The researchers found that hybrid maize is more sensitive to ozone exposure, suggesting possible strategies to improve tolerance.
The UMass Amherst team has made a significant breakthrough in creating ultrathin flexible materials that can self-organize and respond immediately to mechanical force. By modifying the curvature and tension of a membrane, researchers were able to control the positions of tiny solid plates within the membrane.
Women with cardiovascular disease require reproductive planning to ensure optimal health and minimize risks during pregnancy. The American College of Cardiology emphasizes the importance of sharing decision-making with healthcare providers to create an action plan for contraception and medical decision-making.
Researchers developed a new noise-suppression technique that reduces noise photon counts by at least 50 times, enabling accurate 3D imaging up to 201.5 km with single-photon sensitivity. The technique is achieved through optimized transceiver optics and coating the telescope for high transmission.
The American College of Physicians suggests prescribing shorter antibiotics courses for uncomplicated bronchitis, pneumonia, urinary tract infections, and cellulitis, with duration guidelines varying by infection. This approach aims to reduce antibiotic exposure and prevent resistant organisms from developing.
An international team found a strong genetic link between the shape of our face and brain, with 76 overlapping locations. However, this connection does not predict behavioral traits or risk of conditions like Alzheimer's disease.
A study published in Nature Climate Change predicts a significant increase in Arctic lightning strikes by the end of the century. This rise in lightning will drive both wildfires and further warming above the Arctic Circle.
Researchers found a novel genomic signature associated with increased risk of early death from lung cancer. Patients with high expression of these genes have indicators of immune system activity, but also suppressed T cells, which can impact treatment effectiveness.
A new study by the University of Illinois reveals that climate change will impact Colombia's coffee production significantly, with low-altitude regions facing negative effects and high-altitude areas experiencing improved yields. The research provides valuable insights for policymakers and coffee growers, highlighting the need for regi...
A long-term study found that prenatal exposure to inflammatory substances affects stress circuitry function in male and female offspring, retained into midlife. Abnormal levels of pro-inflammatory cytokines produced in mothers during pregnancy affect brain development differences by sex.
A recent study found that a higher percentage of people in Appalachia are unlikely to receive the COVID-19 vaccine compared to national numbers. The researchers also tested interventions to stop the spread of misinformation, finding that subtle warnings from trusted health influencers can make a difference.
A new study finds a correlation between the end of solar cycles and a switch from El Nino to La Nina conditions in the Pacific Ocean. The researchers applied a 22-year solar clock to find this elusive correlation, which could improve predictability of major El Nino and La Nina events.
A new theory suggests that external cues and environmental factors play a crucial role in the development of executive function, which is responsible for controlling behavior. The research team aims to provide practical guidance for childcare providers and parents.
A new USGS study reveals lower reproductive rates and higher movement patterns among piping plovers in the Northern Great Plains, suggesting a higher extinction risk than previously assumed. Habitat quality appears to be key, with better habitats supporting improved reproductive output.
A new study by economists suggests that Black students who attended racially balanced high schools completed significantly less schooling than those who attended predominantly black or white schools. This challenges the standard wisdom that school desegregation leads to racial nirvana in the US.
A new technique developed by HUG-CELL reconstructs livers in the laboratory using extracellular matrix and human cells. The method, which can be used to produce other organs as well, shows promise for increasing organ supply and reducing rejection risks for transplant patients.
Research suggests that biodiversity loss increases exposure to zoonotic pathogens. Restoring nature can prevent future pandemics by reducing the abundance of risky animal species. Biodiversity has a protective effect, and managing this risk requires understanding how human development and habitat conversion affect zoonotic hosts.
Researchers found that nearly half of those convicted of non-consensual image sharing acknowledge shame and tell redemption stories about making better choices in the future. This suggests a need for interventions focused on helping offenders accept guilt and find meaningful ways to repair harm, rather than stigmatizing them.
A study found that US women faced increased health-related socioeconomic risks, leading to higher rates of depression, anxiety, and post-traumatic stress. The survey also showed that nearly half of all women reported new or worsening conditions, with food insecurity being the greatest challenge.
The Deep-time Digital Earth program is a 'big science' initiative that aims to transform research in deep-time Earth Science through data-driven abductive discovery. The program will create an open platform for linking existing deep-time Earth data and integrating geological data, enabling users to explore Earth's evolution by specifyi...
A new web application, SpillOver, evaluates wildlife viruses to estimate their zoonotic spillover and pandemic potential. The tool creates a watchlist of newly-discovered viruses, prioritizing them for further characterization, surveillance, and risk-reducing interventions.
A recent study has deepened our understanding of the SARS-CoV-2 nucleocapsid protein's interactions with genetic material, offering potential avenues for developing effective treatments. The research reveals how the N protein binds to RNA and protects it, and highlights its flexibility as a key factor in this process.
A new interactive tool, SpillOver, prioritizes wildlife-origin viruses based on their risk of spreading to humans. The tool identifies 12 known human pathogens and several newly discovered viruses as being at high risk of spillover.
A new study finds that restoring Louisiana's coastal marshes can store significant amounts of carbon in the soil, potentially altering the global carbon budget. The study examined 24 sites across four marsh habitats and found that protecting these areas is vital to preserving carbon stored in the soils.
The consortium, which includes 32 national medical societies representing over half of America's doctors, will advance climate, health, and equity solutions. The funding supports partnerships with the National Medical Association and empowers doctors to convey the impact of climate change on public health.
Researchers have identified compounds in Baltic amber that show activity against gram-positive, antibiotic-resistant bacteria. These compounds, including abietic acid and dehydroabietic acid, could lead to new medicines for treating infections caused by these resistant bacteria.
Researchers have created a precise map of brain connectivity from the basal ganglia, revealing new details and a surprising level of influence connected to the basal ganglia. The findings offer a blueprint of the area's architecture that could potentially open additional avenues for intervention of Parkinson's disease and other disorders.
A Norwegian University of Science and Technology study found that regret does not contribute to changes in sexual behavior. Women tend to regret casual sex more than men, while men regret missing opportunities more. The researchers suggest that personality plays a significant role in shaping behavior, rather than emotions like regret.
Research using three mouse models of neurodevelopmental disorders found distinct basal metabolism patterns, with varying energy expenditure and fat utilization. The studies suggest all three models may exhibit mitochondrial dysfunction, highlighting the need for personalized treatments and diagnostic methods.
A collaborative team identified multiple genes with recurrent alterations in uLMS, including HRD, ALT, C-MYC/BET, and PI3K-AKT-mTOR pathway, as potential targets for new treatments.
Injections of reflective sulfate aerosols into the atmosphere may relieve worst climate change consequences when combined with carbon emission reductions. However, SAI carries its own risks, affecting multiple environmental factors in complex and unpredictable ways.
Researchers found that high biodiversity in aquatic ecosystems is essential for meeting human needs for micronutrients like calcium and iron. Seafood from biodiverse sources can help combat 'hidden hunger,' a phenomenon where people have access to enough calories but not enough nutrients.
Researchers at NIH/National Human Genome Research Institute developed a breath test to measure how well patients with methylmalonic acidemia respond to liver or combined liver and kidney transplants. The test assesses the severity of the disease and helps determine treatment efficacy.
A new study published in JCI Insights found that COVID-19 convalescent plasma treatment with high levels of antibodies is safe and significantly improves clinical outcomes. The treatment was effective in non-mechanically ventilated patients, with a survival rate of 88.9% at the 30-day mark.
Researchers used single-cell RNA sequencing to track genetic activity in nearly 20,000 cells as they formed an Arabidopsis leaf. They found a surprising abundance of ambiguity in how cells traversed various identities, particularly early on within the stem cell population. The study reveals that cells may double-back on their developme...
Researchers at Kumamoto University found that adult nocturnal fishflies feed on pollen at night, visiting flowers and feeding on nectar. This discovery sheds light on the terrestrial life of adult fishflies, which was previously unknown.
A new paper explores the impact of bridge construction on manatee populations, highlighting entanglement risks and habitat destruction. DISL researchers offer best practices to reduce negative effects.
A South Korean research team has developed a high-efficiency flexible thermoelectric device capable of autonomously generating electricity from body heat. The device features a sponge-like configuration that enhances thermal insulation, allowing it to perform better than existing flexible thermoelectric devices.
Researchers developed a new method to detect multiple types of DNA methylation in individual bacteria and the gut microbiome using nanopore sequencing. This breakthrough enables reliable methylation discovery and high-resolution microbiome analysis.