The study found that almost half of people undergoing treatment when the pandemic began reported using some form of telemedicine. Researchers also noted that use of telehealth for behavioral health conditions was lower among women, older adults, and those with less than a high school education.
This issue of APSB features studies on the anticancer effects of berberine, baicalein's potent antivirus ability against HSV-1, and a new class of PDE10A inhibitors for treating PAH. Additionally, several articles explore innovative drug delivery systems and novel targets for cancer therapy.
The new approach uses dynamic LED lighting to create 3D images without requiring complex synchronization. The researchers achieved a reconstruction error of just 2.6 millimeters using a smartphone and commercially available LEDs.
An international team from Osaka University has reported a novel hybrid emitter that could revolutionize OLED display design. The SiAz material achieved an external quantum efficiency of 4%, making it the best-performing heavy-atom-free OLED to date.
Researchers developed a framework to evaluate climate change adaptations for water and energy systems, finding that conserving water can alleviate electricity grid stress. The study applied this framework to California, highlighting two possible adaptation pathways: one energy-intensive and another that saves both water and energy.
A new study found that marijuana use consistently increases throughout the calendar year, peaking during late fall or early winter before dropping at the beginning of the following year. The researchers believe this may be due to a 'Dry January' effect, where people stop using marijuana as part of a New Year's resolution.
Researchers found that MLL4 controls the production of neurons vital to growth, leading to delayed growth and short stature in patients. Small chemicals mimicking epigenetic actions of MLL4 may help restore GHRH neuron production, offering a potential treatment strategy.
Rice University engineers have created a process that converts carbon monoxide directly into acetic acid, a widely used chemical agent. The electrochemical process uses nanoscale copper cubes and solid-state electrolytes to produce highly purified acetic acid with up to 98% purity.
Researchers have developed a femtosecond laser with unprecedented precision and stability, allowing for the observation of chemical transformations inside cells and the creation of ultra-thin layers on microchips. The laser's harmonic mode locking system enables precise control over pulse frequencies, opening up new avenues for applica...
Researchers at the University of Illinois Chicago developed a new catalyst made from 10 elements that can lower methane combustion temperatures by half. This could lead to a significant reduction in harmful greenhouse gases produced by burning natural gas in households, power turbines, and cars.
A study of Mytilus californianus shells reveals a shift in mineralogical composition over the past 60 years, from aragonite to calcite. Ocean acidification is likely responsible for this change, indicating potential impacts on marine ecosystems.
A recent NIH study found that women who use cannabis while trying to conceive are around 40% less likely to get pregnant each month. The study of over 1,200 women aged 18-40 with one or two miscarriages found no difference in miscarriage rates but noted differences in reproductive hormones involved in ovulation.
A new study published in Nature Sustainability found that more management measures employed in fisheries lead to better outcomes for fish populations. The research team analyzed data from nearly 300 fish populations and confirmed that increased management attention is linked to healthier fisheries.
Researchers at Colorado State University and the University of Cincinnati have discovered a new mode of snake locomotion, called lasso locomotion, which enables brown tree snakes to ascend larger smooth cylinders. This discovery may help protect endangered birds from the snakes' impact.
Two studies reveal that mosaic mutations during embryonic development contribute to the risk of autism spectrum disorder (ASD), with most brains harboring 'point' mutations in enhancers. Additionally, large copy number variants (CNVs) were found in people with ASD, often affecting multiple genes and chromosome regions.
A study by University of Exeter researcher Dr. Patrick English found that minority candidates are less likely to be fielded in areas with lower tolerance for diversity. Only 65 out of 650 potential BAME MPs needed to reflect the UK's minority-ethnic population, highlighting a systemic barrier to representation.
The COVID-19 pandemic had a significant indirect impact on heart disease patients in the US and globally. Deaths from ischemic heart disease and hypertensive diseases increased during the pandemic, while cardiovascular testing disruptions were observed worldwide.
Genetically identical cells can still behave differently after starvation, and researchers have identified key biomarkers that predict which cells will take quiescent or senescent paths. The findings could lead to more predictable responses to pharmaceutical treatments.
A UVA-led team has developed a new approach to power grid planning that incorporates the impacts of hurricanes, reducing costs and emissions. The model simulates the likelihood and intensity of storms, allowing for more efficient infrastructure investments and projected average electricity costs.
A bacterium has been identified that produces the potent substance FR900359, which inhibits Gq proteins with similar potency to no other compound. The discovery facilitates large-scale production of the substance, allowing researchers to explore its therapeutic potential.
David Wetz, UTA professor of electrical engineering, has received a DURIP grant to study the insulation properties of epoxy and additively manufactured materials in compact high-voltage systems. The goal is to identify new ways to improve dielectric properties, reducing system size and weight.
A new polymer patch provides controlled release of a drug blocking COX-2 enzyme, driving pain and inflammation. The patch can provide three to four days of localized pain control for critical post-surgical period.
Researchers developed a CD45-directed antibody radioconjugate to target and deplete specific immune cells. The treatment safely depleted T cells, B cells, NK cells, and Tregs in mice while sparing red blood cells and platelets.
A simple nurse- or carer-led medicines' monitoring system has been shown to reduce medication-related illness in people living in residential care homes. The Adverse Drug Reaction Profile (ADRe-p) system helped identify medicines' mismanagement and adverse drug reactions, leading to improved prescribing and reduced harm.
Researchers at the University of Illinois have developed a new electrochemical reaction using polymers to improve CO2-to-ethylene conversion efficiency. The study found that the new polymer-entrained electrodes produced more stable chemical intermediates, resulting in up to 87% ethylene production, surpassing previous reports.
Researchers discovered that tweaking one layer of atoms on a catalyst's surface can significantly improve its performance in splitting water into hydrogen and oxygen. This breakthrough could lead to more efficient production of hydrogen fuel, a crucial component of renewable energy storage.
Researchers at KIST have developed a breakthrough material design strategy to overcome the problem of high interfacial resistance between solid electrolytes and cathodes in all-solid-state batteries. The new approach improves charge transfer and stability by optimizing the crystal structure of the cathode material.
A study from MIT neuroscientists has identified a hippocampal circuit that stores information about the timing of events, allowing mice to remember when to turn left or right in a maze. Disrupting this circuit impaired their ability to remember direction, but not location.
Researchers at Oregon State University have developed a battery anode based on a new nanostructured alloy that can improve energy storage and replace solvents with seawater. The zinc- and manganese-based alloy suppresses dendrite formation, demonstrating super-high stability over thousands of cycles.
Anti-Black racism in healthcare has significant negative effects on the physical and mental health of Black people. The authors recommend dismantling systemic racism through training, data collection, and increased accessibility for Black students.
Researchers sequenced 107 microalgae species from diverse locations to gain insights into genomic differences in saltwater and freshwater microalgae. The study reveals fundamental differences in nuclear and cellular membranes between the two, with marine species containing more viral-origin genes.
Researchers developed an in vitro human-derived tissue model to study SARS-CoV-2 infection and its progression to ARDS. The model revealed a cellular immune response to the virus, indicating potential for effective treatment with interferon lambda.
The new technique allows researchers to study whole neural circuits in high detail and at scale. They used it to create a comprehensive map of neuronal circuits that control motor function in fruit flies, discovering new sensory neurons.
The study incorporates fluid dynamics and roughness of joint surfaces to evaluate artificial hips, aiming to advance the design of more robust prostheses. The model could help clinicians personalize hip joints for patients depending on gender, weight, age, and gait variations.
A recent study published in Scientific Reports has uncovered evidence of the youngest known occurrence of Middle Stone Age tools, dated to around 11 thousand years ago. This discovery challenges the long-held view that these tool types were replaced by a miniaturized toolkit after 30 thousand years ago.
A pooled data analysis suggests that drinking several cups of coffee daily may be associated with a lower risk of developing prostate cancer. The study found that each additional daily cup was linked to a relative risk reduction of nearly 1%, with the highest intake group showing a 9% lower risk compared to the lowest.
A team of researchers, including K-State's Kyle Goerl, analyzed data from 1,830 quarantined college athletes and found that the risk of COVID-19 transmission decreases after 10 days of quarantine. The study suggests that shortened quarantine periods may be effective in reducing transmission if people follow important mitigation measures.
The CriticalEarth programme aims to develop climate scientists skilled in advanced mathematical theories and the physics of Earth systems. The project addresses two key challenges: abrupt climate shifts and uncertainty in temperature rise predictions.
Russian researchers have proposed a new synthesis method for high-quality graphene nanoribbons, which has a higher yield and is cheaper than the current method. The new approach uses nickel as a substrate and produces multilayer films of nanoribbons, which can be easily separated into individual monolayers.
Research reveals a significant drop in people seeking help for mental illness and self-harm during the first UK lockdown, with treatment gaps greatest for working-age individuals and those from deprived areas. The study found that anxiety disorders decreased by 47.8% and antidepressant prescriptions dropped by 36.4%.
Researchers investigated the flagellar arrangements of 15 unicellular species, revealing their impact on swimming speed and fluid flow architecture. Dinoflagellates were found to excel in both feeding and stealth behaviors due to their unique flagellar arrangement.
Researchers at Columbia University Mailman School developed an early warning system that optimizes surveillance site selection and forecasts the geographic spread of influenza. The method can be applied to other respiratory outbreaks and diseases, providing cost-effective support for public health officials.
The NYU Tandon School of Engineering has received a $2M grant to fund its TRIO Scholars Program, which aims to support underrepresented students in STEM fields. The program provides academic tutoring, financial aid counseling, and career mentoring to help students succeed.
Research reveals that UVA light intensity affects seasonal responses in marine animals, altering behavior and hormone production. The study found a key light receptor involved in responding to UVA light, which was absent in worms lacking this receptor.
Researchers measured pulsar accelerations to clock star motions, revealing tiny accelerations at a few centimeters per second. This opens a new window into galactic dynamics and provides clues in the search for dark matter.
Researchers at Umeå University have made a significant discovery about the diarrhea virus, revealing its ability to survive acidic stomach environments and infect intestines. This understanding could lead to the development of new vaccines, potentially given in edible form, and has implications for tackling diseases like COVID-19.
Researchers used machine learning to design novel reticular frameworks for CO2 separation, outperforming existing materials. The automated platform generates optimal material designs, significantly reducing development time and resources.
A new study found that non-Hispanic white patients are disproportionately placed on liver transplant waitlists, with disparities attributed to private health insurance access and travel distance. The researchers suggest increasing awareness of these trends may promote equitable access to transplants.
A randomized clinical trial evaluated two antibiotic strategies for adults with uncomplicated acute appendicitis. The study found that one strategy resulted in lower rates of hospital discharge without surgery and recurrent appendicitis over a year.
A new study predicts that the number of people suffering extreme droughts will more than double by the late 21st century due to climate change. Global land area and population facing extreme droughts could increase from 3% to 7-8%, posing significant threats to food security and human migration.
Researchers identify human societal tipping points to rapidly cut carbon emissions, citing examples of road transport and power generation transitions. Small coalitions of countries could trigger upward-scaling cascades to achieve more, say experts.
Researchers at KAUST have developed a computational algorithm to simulate ferrofluid behavior, enabling more accurate predictions of the liquid's response to a magnet. By simulating only the surface layer of the ferrofluid, they were able to reduce computational complexity and accurately reproduce complex spike patterns.
Researchers explore co-culture strategies to activate silent gene clusters in microorganisms, leading to the discovery of novel bioactive natural products with diverse and novel structures. These compounds exhibit various bioactivities, including extensive antimicrobial activities and potential cytotoxic activities.
A new study on Megalodon's reproductive biology sheds light on its growth and life expectancy. Researchers found that the shark gave live birth to babies larger than most adult humans, which likely fed on unhatched eggs in the womb.
Researchers at POSTECH developed a new liquid metal ink that can withstand harsh deformation and maintain electrical conductivity, enabling the creation of flexible electronics. The ink was successfully printed on various substrates, displaying negligible resistance changes even when stretched up to 500%.
The parasitic dinoflagellate Hematodinium infects marine crustaceans globally, resulting in mortalities due to organ malfunction. The pathogen has developed into an emerging epidemic threat to China's sustainable crab culture and wild populations.
Researchers have discovered a new material that exhibits both charge density wave and topological metal properties, featuring Weyl points and immense chiral charges. The discovery reveals an intimate connection between topology and electron correlations, opening up avenues for observing axion electrodynamics in condensed matter systems.
Researchers have engineered a new-to-nature metabolic connection, the TaCo pathway, which fixes CO2 instead of releasing it in photorespiration. This synthetic pathway is more energy-efficient than any other proposed alternative, with potential applications in improving crop yield and recycling polyethylene terephthalate (PET).
Researchers developed a new mRNA delivery platform using ZIF-8 nanoparticles that exhibit high mRNA loading capacity, successful endosomal escape, and synergistic GSH depletion. This approach upregulates mRNA translation and improves delivery efficiency compared to existing methods.
Researchers at Tokyo Metropolitan University have designed a new superconductor using high entropy alloys, preserving zero resistivity under extreme pressures. The new compound, Co0.2 Ni0.1 Cu0.1 Rh0.3 Ir0.3 Zr2, has a superconducting transition at 8K, offering a relatively high temperature for an HEA-type superconductor.