A University of Houston study found that diverse recruitment committees can significantly increase the number of women and underrepresented minority applicants. Women-led search committees resulted in 23% more women applying, while URM-led committees attracted over 100% more URM applicants.
A team at Tokyo Medical and Dental University identified four proteins that bind to Toc-HDOs, regulating gene silencing. The discovery provides a novel biological mechanism for Toc-HDOs, increasing understanding of how they silence genes.
Researchers at UNIST developed a novel metasurface with zerogap technology, enabling flexible and durable reconfigurable optics. The technique allows for high modulation depths and can be used in various applications such as electromagnetic wave shielding and polarization conversion.
Researchers identified regulatory variants near the GDF5 gene associated with knee osteoarthritis and hip dysplasia. The study found two distinct mutations that can cause both diseases, paving the way for potential screenings and treatments.
A team from Osaka Prefecture University has developed a method to design and control the path of electron flow in a polycrystalline material, enabling high conductivity in a controllable direction. This breakthrough paves the way for the creation of next-generation thin-film smart devices.
Researchers analyzed molecular analysis data from a pediatric melanoma registry, identifying diverse subgroups and their characteristics. The study found that spitzoid melanomas often have gene fusions and benign clinical courses, while conventional melanoma patients with advanced disease had poorer outcomes.
A study has identified a microRNA-like small RNA encoded by SARS-CoV-2 as a reliable biomarker for stratifying severe COVID-19 patients from mild/moderate ones. This biomarker enables early detection of high-risk individuals, allowing for optimized treatment and improved treatment outcomes.
A new study finds that the microbiome of grasses plays a crucial role in their ability to withstand drought. Healthy bacteria in grasses can provide nutrients, protect against pathogens and UV radiation, and help manage drought. However, under severe drought conditions, the bacterial communities become less diverse and more harmful.
Chromosomal instability linked to cellular senescence in Drosophila study reveals mechanisms that could lead to reduced tumour growth and malignancy. Senescent cells cause inflammation and promote abnormal tissue growth.
Researchers at UNIGE found that chromosomal site location is transmitted through an epigenetic process, allowing offspring to inherit correct positions even without gene information. This epigenetic memory only lasts for one generation and affects the survival of mutant worms.
Researchers at Linköping University developed a method to create structural colours for use in reflective colour displays, enabling manufacturing of thin and lightweight displays with high energy-efficiency. The new method uses electrically conducting plastics and can produce all colours in the visible spectrum.
A new analysis of 27 randomised trials involving nearly 11,000 patients found that interleukin-6 antagonists reduce the risk of death and mechanical ventilation in hospitalised COVID-19 patients. Administering one of these drugs with corticosteroids reduces the risk of death by 17% compared to using corticosteroids alone.
Researchers have successfully connected ultrathin semiconductors with superconducting contacts for the first time, enabling new quantum phenomena and potential applications in electronics. The study uses monolayer molybdenum disulfide with superconducting contacts to exhibit unique electronic properties.
A 15-year study on Guam's native cycad tree found that transplanted individuals have a high mortality rate when introduced to foreign soil, with less than 10% surviving long-term. The results highlight the importance of considering local adaptation for conservation efforts.
Researchers analyzed all relevant COVID-19 studies to determine if cardiovascular drugs affect disease severity, hospitalizations, and deaths. The study found that patients with COVID-19 should continue taking their prescribed cardiovascular medications.
Scientists found that Mercury's large iron core is linked to the early sun's strong magnetic field, which pulled metal grains inward. This discovery sheds light on the formation of rocky planets' cores and their elemental distribution.
Alvarezsaur dinosaurs reduced in size from turkey-sized to chicken-sized around 95 million years ago when they transitioned to an ant-based diet. Their bodies also underwent significant changes, including modified claws and a shift from flesh-eating to termite consumption.
Researchers discover pharmacological activation of p53 triggers viral mimicry response, abolishing tumor immune evasion and promoting anti-tumor immunity. The findings have potential for developing new combination therapies that can increase cancer patient access to immunotherapy.
Scientists at the University of Groningen discovered how a folding protein cytochrome c interacts with mitochondria, leading to programmed cell death. The study found that cytochrome c is partly unfolded during this process, allowing for the regulation of cell death through drug development.
Researchers discovered a code in the liver epigenome that promotes regeneration, enabling pro-regenerative genes to activate when signaled. This finding has potential to inform regenerative medicine for non-regenerative organs like lungs and hearts.
Researchers at the University of São Paulo discovered that SARS-CoV-2 infects and replicates in salivary glands, leading to high viral loads in saliva. The study suggests that tissues specializing in saliva production serve as reservoirs for the virus.
The UK HealthCare team has been awarded a prestigious CDC grant to optimize stroke prevention and care in Kentucky. The three-year grant will focus on implementing comprehensive stroke systems for those at high risk and stroke patients, with the goal of reducing mortality rates and addressing disparities.
Researchers at the Hefei Institutes of Physical Science have developed high-power Er3+-doped mid-infrared lasers with peak powers over 0.33 MW and repetition rates up to 150 Hz. The lasers achieved quasi-continuous signals, making them promising candidates for dental ablation surgery and optical parametric oscillator applications.
Researchers have developed a new method to build nitrogen- and phosphorus-containing compounds from feedstock chemicals using PcFe as a catalyst. The reaction offers high efficiency and yields up to 88% with a low activation energy of 4.8 kcal/mol.
Scientists at ORNL developed a modular design for 3D printing power poles from bioderived materials, enabling quick restoration of electricity after natural disasters. Additionally, they demonstrated wireless charging technology on an autonomous electric vehicle, advancing the transportation industry towards a decarbonized future.
Researchers found that castration of male sheep leads to delayed DNA aging compared to intact males, with epigenetic clocks and DNA methylation patterns differing between the two groups. The study's findings also suggest a link between castration, male hormones, and sex-specific differences in DNA aging.
Researchers have found that our brains use the same cognitive processes to identify both real and imagined human faces. This 'face pareidolia' allows us to quickly detect faces in objects like the moon or cheese on toast, but also enables us to analyze their expressions.
Researchers used AFM-IR, ToF-SIMS, and fluorescence microscopy to study bitumen surface composition and structure. The study found that the surface is heterogeneous, with individual molecular assemblies distributed in a specific pattern.
A group of older adults called 'superagers' have been found to maintain the same level of neural differentiation as young adults, enabling them to create distinct representations of visual information and accurately recall image-word pairs. This study used fMRI to understand how superagers learn and remember new information.
A new study using EDGAR database shows that urbanisation has led to a significant reduction in greenhouse gas and air pollutant emissions in high-income countries. The majority of global emissions occur in urban areas, with some exceptions like NH3 emissions, which are mostly driven by agricultural activities.
A study suggests that known geochemical processes cannot explain the high concentration of methane detected by Cassini spacecraft on Enceladus. Mathematical models suggest that microbial hydrothermal vent activity or abiotic processes could be responsible for the methane production.
At-risk children who participated in a mindfulness curriculum gained an average of 74 minutes of sleep per night, with rapid eye movement sleep also increasing. The study found that the curriculum was protective against sleep losses typically seen during this age period.
Researchers analyzed 99 vinegar fly species to understand how sex pheromones evolve and impact mating behaviors. The study found that male-specific compounds are abundant, while female-specific compounds are scarce, suggesting a crucial role for males in transmitting chemical signals.
A study found that counterfeit dominance negatively impacts Anglo-American consumers' perceptions of authentic luxury fashion brands, while having little effect on Asian consumers. This is due to cultural differences in social-adjustive attitudes, with Anglo-Americans relying more on outgroups and Asians on ingroups.
A study published in Nature Communications suggests that Southeast Asia can decouple electricity supply and environmental protection by embracing renewable technologies like solar energy. The research reveals that only 82% of planned dams are necessary, and halting construction would have minimal impact on electricity costs.
Researchers discovered a link between theta rhythm of the brain and gender differences in attitudes towards risk. The study found that men showed a higher risk appetite than women, with stronger frontal theta asymmetry and oscillations in the anterior cingulate cortex correlating with risk-taking behavior.
Researchers at Penn State designed a synthetic defective SARS-CoV-2 virus that interferes with the real virus's growth, potentially causing its extinction. The therapeutic may be used as a self-promoting antiviral treatment for COVID-19.
Researchers interviewed people receiving palliative care about losing independence with intimate hygiene, revealing the importance of two-way communication and empowering individuals to influence their care. The study aims to raise awareness among health professionals about providing dignified support.
Researchers have identified two new palaeotheriidae mammals, 'Leptolophus cuestai' and 'Leptolophus franzeni', from the Eocene epoch in Spain. These ancient animals had atypical dental features and were smaller than modern horses.
Researchers explore integrating reactive oxygen species generation and prodrug activation to enhance cancer therapy. Stimuli-responsive nanomedicines can target tumors, generating ROS that activate drug release, offering promising synergetic therapy strategies.
The study found that APOBEC4 is highly expressed in cells and tissues attacked by SARS-CoV-2, such as epithelial cells in the lungs and gastrointestinal tract. This knowledge could lead to characterizing antiviral cell status attributed to AID/APOBECs specific to patients and correlating it with organ damage and COVID-19 severity.
Researchers developed a low-cost, accurate gas sensing device that can detect volatile organic compounds (VOCs) in air samples within 10 minutes. The device has potential applications in monitoring indoor air quality and non-invasive medical screenings.
The study found that streams with high detritivore diversity have higher rates of decomposition, but also discovered that the loss of these organisms can slow down this process. The researchers concluded that if detritivores continue to decline, ecosystems will struggle to sustain life due to reduced nutrient recycling.
A study published in Cell Reports has shown that administration of senolytic drugs targeting 'zombie cells' in the scar tissue surrounding spinal cord injuries improves functional recovery. The zombie cells are senescent cells with interrupted growth and division but not programmed cell death, which persist in mammals and contribute to...
A network of ground-based sensors paired with drones can significantly shorten wildfire detection time, giving firefighters a better chance to control the fire. The technology is complementary to satellite imaging and suitable for high-risk regions near human settlements and national parks.
Two model studies document the probability of climate tipping in Earth subsystems, supporting the urgency of restricting CO2 emissions. The findings suggest that abrupt climate changes might be less predictable and more widespread than anticipated, with potential consequences for Western Europe's climate.
Researchers at Kanazawa University developed a chemical reaction that cleaves the bond between an aryl halide and the halogen atom using an organic catalyst with low environmental impact. The process generates an aryl radical, which can be used for organic syntheses and further reactions.
Trihexyphenidyl, a central anticholinergic drug, shows efficacy in reducing PTSD-related nightmares and flashbacks in 88% and 79% of patients, respectively. The researchers found a rapid onset of treatment within 1-2 days.
Researchers developed a chlorine-substituted Na3SbS4 solid electrolyte with improved ionic conductivity and superior electrochemical stability, enabling long-term stability with Na metal anodes. The Cl substitution allows for three-dimensional ion diffusion pathways and reduces interfacial resistance.
The Western Balkans region has developed a 10-point plan to combat the COVID-19 pandemic, prioritizing healthcare systems, climate neutrality, and digitalization. The plan aims to strengthen pandemic preparedness and crisis resilience in the region.
Researchers from the University of Pittsburgh have developed a new method to convert methane into valuable chemicals using photocatalysts, reducing greenhouse gas emissions and waste. The process uses light as an energy source to break down methane bonds, creating fuel and chemical products.
Combining interscalene brachial plexus block with general anesthesia attenuates stress and inflammatory response in arthroscopic shoulder surgery. ISB/GA results in lower epinephrine, norepinephrine, and glucose levels, as well as reduced TNF-α and IL-6 levels.
Scientists from St Petersburg University describe the detailed structure of crocodylian braincases, revealing evolutionary features that enabled powerful jaws. The study resolves long-standing contradictions in the genealogical tree of reptiles and sheds light on developmental mechanisms behind the akinetic skull structure.
A recent study investigated the relationship between switchgrass and soil microbes, revealing that each cultivar harbors a unique community of bacteria and fungi. The research found that root characteristics, such as length and diameter, differ among cultivars and may influence soil microbiomes.
A new method developed by Gayah and Aalto University researcher Murat Bayrak suggests eliminating left turns at busy intersections to reduce congestion. The hybrid approach uses heuristic algorithms to identify the most efficient configurations, banning left turns in city centers while allowing them on periphery roads.
A new study found that memory formation causes neurons to break their DNA, leading to changes in gene expression and potentially undermining brain health with age. The study also discovered that glia play a significant role in establishing memories from fear conditioning.
A recent study published in SLEEP found that teenagers who slept only five hours per night experienced significant depression, anger, and confusion. In contrast, those who slept ten hours reported increased happiness. The study highlights the importance of sufficient sleep for adolescents to mitigate mood deficits.
The study found that longer travel distances to the nearest abortion care facility are associated with higher abortion rates. Reduced travel distances may lead to increased access and subsequently lower abortion rates.
A study found no detection of COVID-19 vaccine-associated messenger RNA (mRNA) in breast milk samples from vaccinated mothers. Researchers analyzed 13 human milk samples and concluded that the mRNA was not detectable.
Research at McGill University found that patented biomedical inventions created by women are more likely to benefit women's health, addressing conditions like breast cancer and postpartum preeclampsia. However, female inventors face significant barriers, including lower commercialization rates and biases in early-stage feedback.