Researchers found that COVID-19 vaccines induce a robust and potentially long-lasting immune response with the formation of germinal centers in lymph nodes. Vaccination led to high levels of neutralizing antibodies effective against three variants of the virus, including the Beta variant from South Africa.
A study published in Cancer Cell found that multiple myeloma patients exhibited a widely variable response to COVID-19 vaccines, with some showing undetectable antibodies after mRNA vaccines. This variation underscores the importance of routine blood tests and continued precautions for these patients.
Researchers at McMaster University have developed a promising new cancer immunotherapy that uses genetically engineered natural killer cells to find and destroy malignant tumors. The modified cells can differentiate between cancer cells and healthy cells, bringing new promise to this branch of immunotherapy.
Amblyopia researcher Mark F. Bear receives a $100,000 grant to develop a new treatment approach based on synaptic plasticity principles. The therapy aims to 'reboot' a formerly deprived eye, restoring vision more fully than traditional patch therapy.
A new study suggests that US presidents with high levels of narcissism are more likely to initiate conflicts with other great power countries, accounting for factors such as political party and military experience. The research found that the top three most narcissistic presidents initiated nearly all of their disputes alone.
Staff handwashing increased by 61% and PPE use rose to 21% after participating in the escape room. The interactive training environment engaged employees, leading to improved retention and patient safety outcomes.
A conclusive narrative review found physical punishment of children is not effective in preventing child behavior problems, but instead predicts increases in behavior problems over time. The study's authors recommend countries end the use of all types of physical punishment on children to protect their development and well-being.
Researchers discovered that lowering iron content in fat cells limits the absorption of lipids by intestinal cells, leading to reduced weight gain and associated health issues. This finding could lead to new therapeutic approaches to protect against obesity and related diseases.
Caballero-Gill's project, part of the CycloAstro Project, focuses on training and developing diverse graduate students and postdocs, emphasizing socially conscious leadership and community engagement. Funding from the Heising-Simons Foundation will support this initiative until May 31, 2024.
Researchers at UIC are expanding testing for vulnerable communities, performing genomic sequencing on samples to identify emerging SARS-CoV-2 strains. This helps gather info on variant dynamics and human immune responses, aiding public health surveillance.
A new study published in the American Journal of Pathology uses Fast IR imaging-based AI to identify tumor type in lung cancer, providing a promising diagnostic method for future testing and treatment prediction. The analysis takes only half an hour, offering a significant improvement over current methods.
Researchers at UCLA discovered that virtual reality environments strengthen theta waves, a key brain rhythm for learning and memory, in rats. This finding could lead to new treatments for disorders like ADHD, Alzheimer's disease, and depression.
A new national study found that children in the United States with greater screen time usage at ages 9-10 are more likely to gain weight one year later. Each additional hour spent on screen time is associated with a higher body mass index (BMI) one year later.
A study published in Nature Communications found that nearly all nitrogen that fertilizes life in the open ocean of the Gulf of Mexico originates from coastal waters. This discovery is crucial for understanding the food web and survival of commercially valuable species like Atlantic bluefin tuna.
A study by the American Cancer Society found a 10.2% decline in real-time electronic pathology reports from population-based cancer registries in 2020 compared to 2019. The study suggests substantial delays in diagnosis and treatment services for cancers during the pandemic.
A microfilter device capable of detecting trace amounts of cancer cells in one mL of blood has been developed by a Kumamoto University research group. The device uses dynamic deformation and nucleic acid aptamers to separate and capture CTCs, achieving a high detection capability and selective detection rate.
Researchers study rare warbler hybrid with mismatched color patterns to disentangle genetic drivers of traits usually inherited together. The team identifies new location in genome linked to black face mask and confirms previously identified region for black throat patch.
Researchers compared observed global energy technology costs for 2019 with technology cost forecasts generated by models and forecasts by human experts. Models accurately forecasted observed costs for 2019 more often than experts, but all methods underestimated cost reductions.
Researchers at UToledo have identified a new sperm movement that helps diagnose and treat male infertility. The study reveals the centriole's role in sperm evolved from a shock absorber to a transmission system, enabling more efficient movement.
A study by Martin-Luther-Universität Halle-Wittenberg found that relationship quality is associated with the subjective feeling of power, rather than a balanced distribution of positional power. Couples where both partners reported high personal power were more satisfied with their relationships.
A new analysis by Temple University researchers found that endovascular stenting is highly effective in treating superior vena cava syndrome, with a success rate of nearly 99%. The therapy has also shown low restenosis and recurrence rates, making it the preferred option for patients with this condition.
Researchers at Boston University School of Medicine discovered that charged biopolymers like heparan sulfate and heparin accelerate amyloid aggregation in various organs. This understanding will guide targeted drug design for deadly diseases such as Alzheimer's, Parkinson's, and type-2 diabetes.
Two studies by CU Cancer Center researchers found that chronic inflammation can serve as a key factor in the development of leukemia. Chronic inflammation reduces the fitness of normal cells, hindering their ability to reproduce and creating space for cancer-causing mutations to proliferate. The findings support the theory of adaptive ...
Research found human hippocampal neurons fire during specific moments in time, encoding information about the time and order of events. These neurons contribute to episodic memories by tracking time and sequence of events.
Researchers at Northwestern and George Washington universities developed a wireless, battery-free pacemaker that disappears after use. The device wirelessly harvests energy from an external antenna, eliminating the need for bulky batteries and rigid hardware.
A randomized clinical trial found that patients matched with therapists who have a strong track record of treating their primary concerns experienced greater reductions in general impairment. This 'match effect' was more pronounced for patients with severe problems and those from traditionally underserved populations.
The CHEOPS satellite unexpectedly detected a third planet passing in front of its star, revealing details about a strange planet without a known equivalent. The exoplanet, Nu2 Lupi d, has a radius 2.5 times that of Earth and orbits its star with an orbital period of over 107 days.
A new approach to molecular drug design has yielded a highly promising bladder cancer treatment candidate that induces rapid shedding of tumour cells and results in significant tumour size reduction. The treatment shows potent effects on patients with non-muscle invasive bladder cancer, demonstrating safety without side effects.
RAMBO, a new method, cuts indexing times for large DNA databases from weeks to hours and search times from hours to seconds. The researchers used a data structure that has a significantly faster query time than state-of-the-art genome indexing methods.
Type II alveolar cells, a major cell type infected by SARS-CoV-2, possess high levels of MHC-II and play a role in improving the outcome of respiratory viral infections. AT2 MHC-II expression is unique and triggers an immune cascade that activates helper T cells.
Researchers found that metabolic activators reduced recovery time for mild-to-moderate COVID-19 patients by 3.5 days. The treatment also improved liver health and decreased inflammatory markers. This study builds on phase two clinical data and demonstrates the potential benefits of metabolic activator therapy in COVID-19 patients.
Researchers at TU Wien discovered a security vulnerability in subdomains, allowing hackers to access sensitive data and compromise websites. The study found 1,520 vulnerable subdomains on 887 of the world's most visited sites, including CNN and Harvard University.
Scientists have developed new methods to retrieve mammalian viruses from water and leech samples, providing a novel approach to pandemic prevention research. The techniques used environmental DNA and invertebrate-derived DNA, allowing for the identification of known and novel viruses in wildlife reservoirs.
Researchers at Nagoya University developed a new synthesis method for nanographenes, using polycyclic aromatic hydrocarbons as templates. This approach enables the creation of multiple nanographenes with varying characteristics, addressing the challenge of identifying relationship between structure and properties.
A new three-year project funded by the Heising-Simons Foundation is integrating science from paleoclimatology, geophysics, and astronomy to study the evolution of the Solar System and Earth-Moon dynamics. The CycloAstro Project will also investigate the Earth's paleoclimate system and improve cyclostratigraphy and astrochronology.
A Rutgers University-led study warns that COVID-19's socio-economic disruptions will drive the coffee industry into another severe production crisis. The researchers conclude that managing coffee leaf rust outbreaks requires a blend of scientific and social solutions to safeguard farmers' livelihoods.
A study evaluated a panel of 142 mutation-signature–associated metrics for predicting cancer progression in patients. The P142 panel successfully predicted cancer progression status in some, but not all, analyzed cancer types.
Researchers at Tomsk Polytechnic University developed a scalable method to produce polytetrafluoroethylene (PTFE) membranes using electrospinning. The membranes demonstrate high chemical stability and biocompatibility, making them suitable for various industries such as petrochemicals, aerospace, and medicine.
The study investigated the association of the IGF/CTP score with overall survival and progression-free survival in CTP class A patients with advanced HCC treated with sorafenib. In these patients, IGF/CTP score B was associated with shorter PFS and OS, indicating a more accurate predictive tool for treatment outcomes.
Researchers found that geologic formations in northern Delaware Basin, with previous hydrocarbon production, have lower pore pressures and no earthquakes. In contrast, southern basin has higher initial pressures and earthquakes. Targeting these sites for carbon sequestration could limit earthquake risk.
The review discusses defect and interface engineering for e-NRR electrocatalysts, emphasizing active sites and intrinsic mechanisms. It highlights the potential strategies to develop more advanced NRR electrocatalysts, promoting the creation of more efficient catalysts for electrochemical nitrogen reduction.
Scientists have discovered a new mineral, allabogdanite, at the Dead Sea that was previously only found in meteorites. The discovery has implications for our understanding of Earth's surface conditions and geological processes.
Astronomers using the CHEOPS space telescope have detected a unique exoplanet, Nu2 Lupi d, which is 9 times the size of Earth and has masses between those of Earth and Neptune. The discovery reveals that the planet has a mild stellar radiation environment, making it an ideal target for studying its composition.
A simulation study found that wind farms generate little power beyond a certain size, causing interference with neighboring installations. Optimizing arrangement and placement of turbines can increase power density up to a site-specific point.
Research reveals that the deletion of two amino acids in the spike protein makes the virus twice as infective, allowing it to replicate efficiently despite other mutations. This mutation has been found globally, particularly in Europe, Africa, and Asia, and may explain its widespread spread.
A new study found that mangrove forests in Florida suffered unparalleled dieback after Hurricane Irma due to human-made obstacles and changes in natural topography. The research team identified potential explanations, including restricted water flow between areas, which can lead to extreme conditions and degradation of wetland vegetation.
Researchers aim to detect malware in IoT networked devices using a principled approach. They plan to develop resource-aware distributed malware detection and reliable feature extraction methods.
Researchers have developed wearable biosensors that can be integrated into standard face masks to detect SARS-CoV-2 and other pathogens. The technology, called wFDCF, involves synthetic biology reactions embedded in fabrics, providing rapid detection with accuracy comparable to PCR tests.
Researchers found that COVID-positive trauma patients have a six times higher risk of death and double the likelihood of complications compared to those without COVID. The risks were even greater in patients over age 65.
Researchers at UPF BMAT and Music Technology Group develop AI algorithm to determine audible music on TV productions, helping distribute copyright fairly and efficiently. The LoudSense project aims to provide an innovative service to the international music industry.
A new machine learning technique using everyday item images improves detection of respiratory diseases like COVID-19 and pneumonia in chest x-rays. Researchers used transfer learning to bypass the need for large amounts of medical data, reducing training time.
Researchers have developed a new mouse model that mimics Alzheimer's neurodegeneration without relying on the pathogenic proteins amyloid or Tau. The GluN3A knockout mouse model highlights the role of calcium and neuronal hyperactivity in driving neurodegeneration, providing potential leads for new treatments and preventive strategies.
A novel face mask detects Covid-19 in 90 minutes via embedded sensors, offering a new way to monitor healthcare workers' exposure. The technology also enables wearable biosensors for first responders and military personnel.
A study of 65 infants reveals stable individual differences in their responses to impossible events, which predict explanation-based curiosity at 3 years of age. The research suggests that detecting prediction errors in infancy may be a crucial aspect of later cognitive development.
Researchers have designed a miniaturized device using microplasma technology to treat middle ear infections. The treatment is effective in inactivating bacteria and may offer an alternative to antibiotics, which are often ineffective or lead to antibiotic resistance.
Researchers have collected high-pressure data from deep-sea boreholes in a subduction zone, revealing pressures up to 5 megapascals greater than typical hydrostatic pressures. This discovery sheds light on the origins of slow earthquakes and their potential role in triggering larger earthquakes.
A newly discovered fossil deposit, Haiyan Lagerstätte, contains exceptionally preserved soft-bodied organisms and rare juvenile fossils. The study provides a unique glimpse into how these ancient animals developed from larvae to adults.
Researchers developed a novel treatment using stereotactic ablative radiation (SABR) to deliver high doses of radiation to tumor vein extensions. The approach has shown promise in reducing metastases and improving patient outcomes.
Researchers found that inflammatory markers were high when patients experienced episodes of rhabdomyolysis, and lower when they were well. The team identified a 'cytokine storm' as the underlying issue, which can be triggered by an unknown mechanism in VLCADD patients.
A randomised controlled trial of 550 young people found two doses of CoronaVac to be safe and provoke a strong antibody response. Most adverse reactions were mild or moderate, with pain at the injection site being the most commonly reported symptom.