A small study found that COVID patients' brains display similar molecular changes to those with Alzheimer's disease, including increased phosphorylated tau and defective ryanodine receptors. The findings suggest a link between the immune response and neurological symptoms in long COVID patients.
Researchers found that starting DOACs within 1-4 days after stroke onset reduces stroke recurrence without increasing major bleeding risks. The '1-2-3-4-day' rule is proposed as a feasible real-world clinical setting guideline.
Researchers have identified a new highly virulent HIV variant in the Netherlands, known as VB variant, which shows significant differences in immune system recovery and survival compared to other variants. Early diagnosis and treatment are crucial to prevent damage from this more rapid decline in immune strength.
Researchers detect hundreds of major methane releases linked to global oil and gas extraction activities, with a one-year comparison to 20 million vehicles. Limiting these emissions could mitigate climate effects and save billions of dollars for fossil-fuel-producing countries.
In young adults, women are at a higher risk of ischemic strokes, with a 44% greater incidence compared to men. Researchers highlight the need for further research into the causes and non-traditional risk factors that contribute to this disparity.
Research at Rensselaer Polytechnic Institute finds that over 90% of people who use online delivery services would likely revert back to their original way of shopping. Delivery service users access products in four categories: groceries, food, home goods, and other items, with grocery deliveries having the highest proportion of new ado...
A new research synthesis suggests using tree ring data from forest inventory plots to estimate carbon sequestration in forests. This approach could provide a direct record of the carbon gained by individual trees and forests, scaling up to estimate forest-wide and continent-wide carbon savings.
A quality improvement initiative at 10 US children's hospitals has led to an almost 80% reduction in opioid prescribing for children after appendectomy, without harming patient outcomes. The study used a standardized prescribing protocol and ACS NSQIP Pediatric data to minimize opioid prescriptions.
A study by Academic Analytics Research Center found a significant increase in journal article publications (64%) and decrease in book publications (34-54%) across 12 Social Sciences disciplines from 2010 to 2020. This shift may impact library acquisitions strategies and affect humanities-related fields.
Researchers developed a waterproof biosensor that can accurately detect changes in potassium and sodium ion levels important in TBI. The chip features electronic components that produce an electrical signal when sensing chemicals, and the team successfully tested it in artificial cerebrospinal fluid and human blood serum.
Regular exercise boosts tear quantity and film stability to relieve dry eye symptoms. Studies show even low-intensity activity can improve ocular health.
Researchers at the University of Pittsburgh have discovered how 'polyglot' neurons encode and decode sensorimotor chatter, enabling the differentiation between motor and sensory signals. This breakthrough has vital applications in brain-computer interfaces and neuroprosthetics, where accurate decoding is crucial.
A new study published in The Lancet Oncology found that aromatase inhibitors are more effective than tamoxifen at reducing the risk of breast cancer recurrence in premenopausal and postmenopausal women. Aromatase inhibitors were shown to be particularly beneficial for younger women, reducing the risk of recurrence by 30%.
Researchers at NYU Abu Dhabi have published a comprehensive review of 50 fundamental traffic models using an extensive data set of 2.3 billion vehicle observations from 25 cities worldwide. The study found that a non-parametric model outperformed other traffic flow models, regardless of road type and congestion level.
A study by Portland State University found that only 16 transit-oriented developments across the US were fully affordable to low- and moderate-income households. The research highlights the need for policies and regulations to promote affordable housing in TODs, such as requiring a share of affordable units in public property projects.
A team of researchers used wastewater-based epidemiology to detect SARS-CoV-2 in more areas of the Olympic village than clinical testing indicated. The study found that daily screenings missed asymptomatic and post-quarantine patients, highlighting the need for alternative methods.
Researchers analyzed data from over 35,000 adults who had no history of stroke or dementia. Those with optimal cardiovascular health showed a 2.4% higher brain volume, equivalent to a 7-year younger brain. Good blood pressure control and healthy blood sugar levels also contributed to healthier brain imaging measures.
A study in rats found that mothers with sleep apnea during pregnancy may have an increased risk of their male offspring developing autism-like behaviors, including impaired cognitive and social function. The findings suggest a potential mechanism for the link between maternal sleep apnea and neurodevelopmental disorders.
A study at a midwestern university examined the relationship between vaccine coverage and the transmission of SARS-CoV-2 variants during in-person learning. The results showed a correlation between higher vaccination rates and reduced spread of variants, highlighting the effectiveness of vaccines in mitigating COVID-19 transmission.
Researchers in Japan evaluated the cost-effectiveness of adding dipstick hematuria screening to a mass health check-up program. The study found that including routine testing for hematuria would promote early detection and treatment, leading to cost savings and improved patient outcomes. This cost-effective approach has the potential t...
Research shows that couples who took Family Foundations classes 10 years ago had more positive family relationships during the pandemic. They reported lower levels of negative mood, behavior problems, and sibling conflict in their children.
Researchers tracked 10,000 galaxies and clusters over 11.5 billion years, revealing complex motions influenced by gravity and the Big Bang theory. The study provides new insights into the formation history of large-scale mass structures in the universe.
A study published in Risk Analysis found that individuals who endorse libertarianism and anti-egalitarianism attitudes are more likely to disregard COVID-19 risks. This suggests that simply identifying as liberal or conservative may not capture the full scope of political ideology's impact on attitudes toward science issues.
Researchers found a brain region, dorsal precentral gyrus, monitors auditory feedback to produce smooth speech. Hearing one's own voice with unnatural delays leads to increased activity in this region and the superior temporal gyrus.
A study of 1.1 million pregnancies in Denmark found a significant association between seasonal patterns and the rate of extremely preterm births. The analysis revealed that rates of extremely preterm births were higher during the winter months.
Researchers have identified a germline biomarker signature that can predict serious side effects in up to 3 in 10 patients undergoing anti-PD1/PDL1 therapy. The findings represent an important step toward personalizing checkpoint therapy, potentially improving patient outcomes and reducing harm.
A new study found that crowdfunding has limited success in helping people pay their medical bills, particularly in low-income and under-insured communities. Despite raising over $650 million annually, 33.8% of campaigns remain unfunded, highlighting the need for better health insurance coverage and social assistance programs.
A PSU-led research team will investigate microplastic sources and movement across the Columbia River Basin, aiming to secure a larger grant. The project involves diverse stakeholders and will develop an educational course for K-12 educators.
Researchers at Wellesley College found that people frequently misinterpret bar graphs, with one in five graph readers categorically misunderstanding averages. The 'bar-tip limit error' occurs when viewers interpret the tip of the bar as the outer limit of the data, despite the average being the balanced center point.
Researchers found that pregnant people at risk of severe COVID illness regardless of trimester. Vaccination rates among pregnant women remain low despite evidence showing vaccines can help prevent severe illness during pregnancy.
Researchers at UC3M have developed a mathematical model that analyzes the appearance of oscillations in flow networks, which may help explain how blood circulates in the brain. The model takes into account the size of the network and predicts the frequency of pressure oscillations.
Scientists from over a dozen institutions will collect water samples, measure light levels, and net tiny zooplankton to better understand the impact of climate warming on Great Lakes ice cover, water movement, and lake biology. This event aims to fill knowledge gaps in winter limnology.
Researchers have developed a method to assess drug potential for rare disorders by profiling FDA-approved drugs. The study identified NMD modulators that could potentially treat hundreds of disorders associated with nonsense-mediated RNA decay.
A study published in Applied Economics analyzed the relationship between precious metal commodities and equity markets, revealing that gold and aluminum are the most desirable metals for investment. The research also found that copper and zinc have the largest spillovers on global equity indices.
New research reveals that one in three US stroke survivors experience food insecurity, which can exacerbate cardiovascular disease and stroke risk. Healthcare professionals can play a crucial role in addressing food insecurity by engaging with patients and providing support or resources.
A study found that switching from a metered dose inhaler to a dry powder version for maintenance therapy reduces the carbon footprint of people with asthma by more than half. The researchers conclude that this substitution is an acceptable and worthwhile option for most patients who can safely manage their condition at home.
A new study by Wake Forest School of Medicine found a significant link between food insecurity and higher infant mortality rates in North Carolina. The study analyzed health data from all 100 counties in the state, finding that infants in North Carolina had a 36% higher mortality rate compared to national averages.
Researchers propose using NFTs to give patients agency in accessing and sharing their PHI. This technology could improve transparency, efficiency, and security in health information exchange.
A USC discovery demonstrates the safety and efficacy of a stem-cell derived retinal implant for treating advanced dry age-related macular degeneration. The implant successfully improved visual function in some patients and survived without rejection for up to two years.
Researchers detect four cryptic variants of SARS-CoV-2 in NYC wastewater samples, suggesting possible animal origins. The variants' mutations could help identify the next variant of concern for COVID-19.
A phase 2 clinical trial found that the Australian-developed neonatal rotavirus vaccine RV3-BB was safe and produced a robust immune response in African babies. The reduced dose of the vaccine generated an equivalent immune response as the highest dose, offering opportunities to reduce vaccine manufacturing costs.
QUT researchers explore using organic transistors as wearable health sensors, promising comfortable wearability and efficient monitoring. The technology has the potential to revolutionize healthcare with applications in electrophysiology, neuron stimulation, and more.
Scientists have developed a gene-silencing tool that can quash gene activity across generations using small noncoding RNA molecules. This technique, called piRNAi, has expanded the molecular toolkit for gene manipulations and allows for more detailed investigations in nematode worms.
Researchers developed an algorithm that incorporates customer behavior into recommendation systems, making more accurate and personalized suggestions. The technique, known as tensor decomposition, analyzes data in multiple dimensions to capture complex patterns and relationships.
Research suggests that high blood pressure during young adulthood may contribute to changes in the brain later in life, increasing the risk for cognitive decline. A study of 142 adults found significant brain changes in midlife, averaging age 55, linked to vascular risk factors.
A study by Tufts researchers found that telehealth appointments can be effective when augmenting in-person health-care visits, particularly for patients with chronic kidney disease. However, people of color were largely dissatisfied with telehealth due to concerns about care quality and lack of accessibility features.
A study of over 64,700 Black adults found that those born in the US had a higher rate of death from cardiovascular diseases and all causes compared to those born in other countries. The researchers suggest that early migration may have a 'carryover' effect on mortality rates.
A new study from Oregon State University found that people with disabilities have been experiencing high levels of depression and anxiety during the COVID-19 pandemic. Social isolation was a major predictor for both conditions, exacerbated by limited access to healthcare, including delayed or canceled medical appointments.
Children who receive repeated seasonal flu vaccines develop antibodies that provide broader protection against new strains, including pandemic viruses. This finding informs the design of a universal influenza virus vaccine for children.
A new radiocarbon dating method has been developed to accurately date tsunami deposits, offering insights into past disasters and their frequency. Researchers have found that giant tsunamis have occurred at intervals of 100-200 years since the 1611 Keicho Oshu Tsunami.
Researchers developed an algorithm that prioritizes reliable news sources based on audience diversity, reducing the spread of misinformation. The new strategy incorporates data on web traffic and self-reported partisanship to promote diverse news sources.
Researchers found trametinib to significantly improve progression-free survival and objective response rate in low-grade serous ovarian carcinoma. The median PFS was 13 months, while the ORR was 26%.
Researchers found pedal bikes increased bus rides by 1%, while electric bikes took that to 2.1%. The system supported ridership, particularly for socioeconomically disadvantaged and young people.
Researchers at Institut Pasteur have found that certain anti-HIV-1 antibodies can prevent infected cells from releasing viral particles, thereby halting viral spread. These Y-shaped antibodies form chains with viral particles, creating a structure that traps viruses and prevents infection of new cells.
A study examining national data of adults aged 60 and older found that smoking is strongly linked to poor brain health, independent of other medical conditions. Smoking was associated with lower cognitive test scores in this population.
Researchers identified the dorsal precentral gyrus as a critical region in controlling speech, enabling individuals to adapt to feedback errors. This finding may lead to targeted treatments for conditions like stuttering and Parkinson's disease.
A clinical trial found that trametinib significantly slowed ovarian cancer progression by 13 months and increased treatment response by fourfold compared to standard care. The drug showed promise as a new standard of care for low-grade serous ovarian cancer, a common but difficult-to-treat form of the disease.
Chemists at Scripps Research have found that cyanide can drive metabolic reactions to create carbon-based compounds from carbon dioxide, expanding our understanding of the origins of life on Earth and its potential for existing elsewhere. This discovery opens up new avenues for searching for extraterrestrial life.
A recent study by Oregon State University found that night shift nurses are more likely to suffer from poor sleep, PTSD, depression, anxiety, and inflammation. The researchers also discovered a significant disparity in sleep quality among Black nurses, highlighting the impact of systemic racism on their health.
Researchers analyzed data from hospitals in the US, Australia, and New Zealand to compare alteplase and tenecteplase for treating ischemic strokes. The study found that patients treated with tenecteplase had significantly lower rates of serious bleeding into the brain compared to those treated with alteplase.