Researchers have identified a subset of neurons in the mammillary body that are most susceptible to neurodegeneration and hyperactivity in Alzheimer's disease. These findings suggest that this region may contribute to early symptoms of the disease, making it a potential target for new drugs.
Researchers developed a dual-modality imaging technique combining photoacoustic and super-resolution ultrasound imaging to detect physiological and biochemical abnormalities. The new method provides comprehensive diagnostic information at a lower cost than traditional techniques.
A new study found that quality of heart failure care is equitable for 11 of 14 evidence-based clinical care measures, with no disparities in care between Black and white patients. However, the study highlights areas for improvement, including gaps in care quality and social determinants of health.
Using mice, researchers successfully converted scar tissue back into functioning cardiac muscle using RNAs and exosomes, offering new hope for reversing heart attack damage. The study also sheds light on the aging process's impact on cellular reprogramming.
The PRISM-LT project aims to create an adaptable platform for 3D bioprinting of living tissue with dynamic functionalities and predictable shapes, using a novel tunable bioink that fosters a symbiotic relationship between stem cells and microorganisms.
A study of 20,311 US adults aged 51–100 years found that higher educational attainment protected against cognitive decline differently for Black and Latinx adults compared to White adults. Higher-educated White adults received the greatest protection, while Latinx adults experienced a later onset of cognitive decline.
Researchers have identified a new degradation mechanism in organic solar cells involving twisting of polymer chains, which reduces efficiency. This discovery paves the way for more stable solar cells that can generate electricity from sunlight at scale.
A global study published in Cochrane Reviews found that consuming cranberry products reduces the risk of repeat symptomatic UTIs in women by more than a quarter. The review also showed benefits for children and people susceptible to UTIs following medical interventions, with minimal side effects reported.
Researchers developed a machine learning model that predicts strokes more accurately than current systems, using data available at hospital arrival. The model achieved high precision and sensitivity, outperforming existing scales.
Dae Kim, MD, MPH, ScD, will receive the 2023 Thomas and Catherine Yoshikawa Outstanding Scientific Achievement in Clinical Investigation Award for his work on frailty research. His contributions have significantly impacted clinical care, particularly in primary care groups using the claims-based frailty index to risk stratify patients.
Researchers have discovered a link between iron redox and Alzheimer's disease, which could lead to the development of new drugs to treat the condition. The new imaging technique allows for the simultaneous detection of two forms of iron in cells and tissue, providing insights into its role in destroying brain cells.
Researchers developed a new framework for modeling task-switching, mimicking human behavior. The framework revealed two regions of the model's 'brain' doing each task, explaining the switch cost and potential benefits of splitting tasks.
A new report by the USGS and FEMA estimates that earthquakes cost the nation an average of $14.7 billion annually in building damage and associated losses. The report's updated estimate is twice the previous annual figure due to increased building value and improved hazards analysis.
A study presented at the ARRS Annual Meeting reveals institutional variability in projection order and image acquisition timing for CEM protocol. Earlier-obtained recombined imaging is significantly preferred for cancer lesion characterization, with a trend towards prioritizing imaging the side of pathology.
Researchers identified a protozoan parasite as the cause of mass sea urchin die-offs in the Caribbean, which has devastating effects on coral reefs and fish populations. Healthy coral means healthy fish, and their positive impacts continue up the food chain.
A new study found that people of diverse cultures, including those from England, Italy, Poland, and Russia, tend to help others in everyday life. The researchers analyzed video recordings of social interactions in 350 individuals from eight languages and cultures and found that the human tendency to help others is a universal principle.
The Grambank database provides an unprecedented level of detail on language structure, showcasing the diversity of human languages. Researchers found that languages exhibit greater similarity to their common ancestors than those they are in contact with, highlighting the importance of genealogical constraints on linguistic diversity.
A study involving over 4,700 people from diverse ethnoreligious populations found that participants showed increased generosity when prompted to think about God. The researchers discovered that belief in God may promote positive intergroup relations and cooperation across religious divides.
A study of 415,000 US female breast cancer deaths from 2011 to 2020 found that Black women should start screening earlier than previously recommended. Health policy makers and clinicians may consider an alternative approach with race- and ethnicity-adapted age recommendations for breast cancer screening.
Researchers analyzed Google Trends data to understand interest in human rights globally, finding steady demand across the globe. Key findings suggest that people in countries like Uganda and Guatemala frequently search for information on human rights, with relative rates surpassing those of other important concepts like malaria.
Two natural coumarin compounds, 5-MOS and 6-MOS, have been identified in the orange climber plant, exhibiting aggregation-induced emission properties. These compounds can clearly identify mitochondria in live cells without additional processing, making cell imaging easier and faster.
A new study published in The Lancet finds that minimum unit pricing for alcohol is associated with a 13% decrease in deaths from alcohol consumption in Scotland. The policy has also led to significant reductions in alcohol-specific hospitalisations and long-term conditions, such as alcoholic liver disease and alcohol dependence syndrome.
A recent study found that learning multiple new tasks improves cognition in older adults, with scores increasing by two to three times. The study, which had six and 27 participants aged 66 and 69, showed that cognitive abilities continued to grow over time, reaching levels similar to those of undergraduates.
Researchers have developed a new composite fabric that combines conventional aramid with carbon nanotubes and polyacrylate to create puncture-resistant materials. The new material outperforms existing fabrics in simulated stabbing tests and could be useful in military and civilian applications.
Researchers investigated Hardy nonlocality using quantum computers, discovering increased success probability as the number of particles grows. This challenges classical theories and has implications for quantum mechanics and communications.
A UC Riverside study found that breastfed infants exposed to alcohol through their mother's milk experience reduced body and brain weights, as well as decreased cortical lengths. The research suggests sex-specific differences in the effects of lactational ethanol exposure on infant development.
A nationwide survey in the Central African Republic found a severe health emergency with a 5.6% mortality rate, four times higher than UN estimates, and widespread malnutrition, food insecurity, and violence, with 82.3% of households reporting adults ate ≤1 meals per day
A recent study published in JAMA Psychiatry found that individuals with a family history of depression exhibit reduced cognitive abilities. The research highlights the potential impact of genetic and environmental factors on brain development and aging, as well as modifiable lifestyle factors.
Researchers at Brown University developed a new microscopy technique using blue light to measure electrons in semiconductors and other nanoscale materials. This breakthrough enables the study of critical components that can help power devices like mobile phones and laptops.
Researchers found fish and bottlenose dolphins react differently to life in noisy shipping corridor of Charleston Harbor Estuary. Fish calls and choruses decreased with increasing anthropogenic noise, while dolphins ramped up their vocalizations. This study highlights the impact of human activities on marine wildlife.
Researchers at Gulbenkian and Cornell University will investigate cell size scaling laws in budding yeast to understand evolutionary mechanisms. The three-year project aims to reveal the physical limits of cell size and how cells modulate their size control.
A new online tool, CogDrisk, has been found to be effective in assessing dementia risk, providing a personalized report for patients and GPs. The tool uses a combination of statistical methods and modifiable risk factors to predict dementia risk, including physical activity, obesity, high blood pressure, smoking, and poor diet.
A study by Brigham researchers reveals that childhood trauma and biological sex are associated with epigenetic changes in functional movement/conversion disorder. Female patients and those with an history of childhood trauma show distinct profiles of epigenetic changes linked to this condition.
Research suggests that agritourism and direct farm sales complement each other in the same community, increasing revenue for farmers. The study identified hotspots of farms engaging in these activities in various regions, including the Northeast, West, and Great Lakes areas.
A study found that some of the world's largest slaughterhouses reduced cattle-driven deforestation in the Amazon by 15% through their zero-deforestation policies. If fully implemented, these policies could halve cattle-driven deforestation in Brazil by sparing over 24,000km2 of forest.
The 18th Key Symposium on Healthy Ageing and Longevity takes place in Okinawa, bringing together world experts to discuss the latest research on blue zones. The symposium aims to promote both longevity and healthy ageing to reduce age-related diseases and healthcare burden.
A new patient-centered approach identifies melanoma patients most likely to benefit from sentinel lymph node biopsy, offering a more accurate and cost-effective method for selecting patients. The study found that adopting a 10% cutoff for positivity rates could help identify patients best eligible for the procedure.
A new URI study reveals that the association between life expectancy and income inequality is not as clear-cut as previously thought. In high-income areas, life expectancy was higher in regions with higher income inequality, suggesting that income inequality may not be a reliable predictor of population health outcomes.
Researchers successfully isolated infectious SARS-CoV-2 particles from hospital air samples collected over a year ago, demonstrating the presence of viable virus particles in aerosols. This breakthrough provides new insights into airborne transmission and informs the development of preventive strategies.
A study published in Cell Reports found that rodents exposed to microgravity had altered gut microbiomes, which may contribute to bone loss. The researchers also discovered that certain bacterial species in the gut produced molecules that influenced bone remodeling.
A recent study published in Nature has identified specific brain areas that integrate planning, purpose, physiology, behavior, and movement. Researchers found that stimulating certain areas of the brain can calm both the body and mind, providing new insights into the mind-body connection.
A study by Ohio State University researchers found Steenstrup Glacier in Greenland is retreating at an unprecedented rate, with a 5-mile retreat and quadrupled velocity between 2018 and 2021. The glacier's rapid change reveals that even long-term stable glaciers are susceptible to sudden and rapid retreat due to warming waters.
A study of over 7,000 patients found that Black and socioeconomically disadvantaged patients with vascular disease have more severe symptoms before bypass surgery and are at greater risk for amputation and other complications after the procedure. Advanced disease accounted for up to half the effect of race on odds for amputation after ...
Replacing sugary drinks with healthier options like coffee, tea, and plain water is associated with lower rates of early death among adults with type 2 diabetes. The study found that increasing consumption of these beverages was linked to a lower risk of cardiovascular disease-related mortality.
A recent study suggests that India's recurrent heatwaves have a significant socioeconomic impact on the country, weakening its progress toward achieving sustainable development goals. The study found that nearly 90% of the country is in danger zone from heatwave impact and around 20% is highly vulnerable to climate change.
Researchers identified a single-celled organism called a scuticociliate as the cause of a massive die-off event among long-spined sea urchins in the Caribbean and along Florida's east coast. The team used genomic techniques and lab experiments to confirm the source of the die-off, replicating what was observed in the ocean.
A new study by Texas A&M University researchers shows that exposure to ultrafine particles during pregnancy enhances the risk for respiratory viral infections, including influenza. Pregnant women are already at increased risk for severe flu, and air pollution exacerbates this vulnerability.
Researchers at ICFO have successfully teleported quantum information over 1km using a multiplexed quantum memory. The technique enables fast and reliable quantum communication over long distances, with potential applications in secure telecommunications.
A drug called teriflunomide has been found to delay the first symptoms of multiple sclerosis in people with radiologically isolated syndrome. In a preliminary study, researchers found that those taking teriflunomide had a 72% lower risk of experiencing first symptoms than those taking a placebo.
A research team from Tokyo University of Agriculture and Technology has developed an image-based AI model to predict the deformation of a splashing drop. The trained encoder-decoder successfully generated image sequences that show the deformation of a drop during impact, demonstrating accurate predictions.
A recent study found a significant rise in cannabis exposures in suspected suicide attempts, with the majority involving other substances. The data highlights the need for increased mental health services and awareness about the risks of cannabis use, particularly among youth.
According to the study, 50 countries' climate plans predict 12 gigatons of CO2 emissions annually by 2050, which must be removed from the atmosphere. The researchers emphasize the need for rapid reductions here and now, as relying solely on technology and nature restoration may not be sufficient to meet this goal.
A recent analysis of three clinical trials found that the UVA-developed artificial pancreas improved blood sugar control by 13 percentage points and decreased hemoglobin A1c levels. The device spent an average of 2.8 more hours per day in target blood sugar range, benefiting both kids and adults with diabetes.
A study by University of Alabama at Birmingham researchers reveals that cadmium-induced inflammation increases the severity and mortality of lung infections. The findings suggest that targeting the regulation of PPAR-gamma in macrophages may protect against severe pneumonia.
Surgery may provide faster relief in pain and disability for people with sciatica, but benefits last only up to 12 months. The certainty of evidence is low to very low, suggesting it might be an early management option for those who value rapid improvement over potential risks.
Researchers at Cornell University found that employees who are not in positions of power can become more creative when given time to warm up to a task by engaging in it multiple times. This challenges the idea that power boosts creativity and suggests a simple intervention to empower all employees.
Researchers used drones to capture images of corn fields damaged by wild pigs in Texas, finding an average loss of 3,416 kg of corn per hectare and a direct cost to producers of up to $48.24 per hectare. The damage occurred mainly in later growth stages, when corn ears were maturing.
A diet high in fruit and vegetables is associated with a lower miscarriage risk, with significant reductions seen for each food group. The meta-analysis of 20 studies found that consuming high amounts of fruit may reduce the risk by up to 61%, while high vegetable intake is linked to a 41% reduction.
A new study reveals that certain wellbeing-related factors, such as household income, internet access, and air pollution levels, are associated with economic growth in European Union countries. Western Europe's strong link to economic growth is attributed to disposable household income, inter-regional mobility, and housing, whereas Cen...
Researchers developed a powerful simulation model that predicts the conformability of flexible electronics on spherical surfaces. This allows for faster design process, determining optimal design without needing extensive experiments.