A treatment combining two antibodies against SARS-CoV-2 strongly protected high-risk people with early COVID-19 symptoms from hospitalization and death. The treatment was effective against the delta variant and appeared safe, with significantly lower reports of side effects compared to a placebo.
A new Bi-containing compound, LaBi1.9Te0.1O4.05Cl, exhibits high chemical and electrical stability and a high oxide-ion conductivity superior to other materials at low temperatures. The unique mechanism underlying the high conductivity is explained by an interstitialcy migration of oxide ions through the lattice and interstitial sites.
Oceanographers warn of limitations in carbon dioxide removal, emphasizing the need for rapid emission cuts to limit global warming. Clear definitions of marine heatwaves are also crucial for coastal communities to adapt and resource managers to prioritize mitigation strategies.
Researchers found that melanocyte stem cells, responsible for hair color, lose their ability to mature and maintain hair color as people age due to getting stuck in the skin. The study showed that these 'stuck' cells cease regenerative behavior when they're no longer exposed to WNT signaling, leading to graying and loss of hair color.
Researchers have visualized how DNA loops are formed through the interaction of cohesin, CTCF proteins, and DNA tension. The study reveals that DNA tension plays a crucial role in regulating the positioning of loops along the genome.
Researchers found that enhancing NMDAR function via increased serine racemase expression improved attention and cognitive flexibility in middle-aged rats. Upregulating serine racemase in the medial prefrontal cortex also increased glutamatergic synaptic transmission, including NMDAR activity.
A new study by Van Andel Institute scientists identifies KDM5C as a key driver of low bone density, preserving bone mass in mice. The discovery may lead to more effective treatments for women with osteoporosis, reducing the risk of fractures and improving quality of life.
Research found that people with epilepsy living in disadvantaged neighborhoods have worse cognitive outcomes, including lower intelligence scores and more depression symptoms. The study suggests a link between social determinants of health and epilepsy outcomes.
Researchers at ANU and AMRI used micro-CT scans to study a fossilized plesiosaur's stomach contents, finding 17 previously undiscovered fish vertebrae. This study provides insights into the evolutionary history of extinct organisms and helps predict how modern marine life may respond to climate change.
A study at Kyoto University has demonstrated the computational power of ecological networks, providing a new direction for rapidly developing AI technologies. The researchers developed two types of ecological reservoir computing that efficiently process information and can be utilized as a computational resource.
Scientists at the University of Córdoba develop biodegradable materials from agricultural waste to clean air. The new material, with a three-dimensional structure, increases photocatalytic particles' exposure to light, resulting in enhanced air purification.
A new study reveals that Indigenous groups in the western US are struggling to turn their legal right to water into actual water use, despite having settled their water-rights claims. The findings show that tribes are likely using only a fraction of their entitled water rights, resulting in significant revenue losses.
Artificial intelligence is being used to improve the fluidic catalytic cracking process, a key step in making heavy crude oil into gasoline and other products. The method uses neural networks to analyze large amounts of data and identify patterns that can signal potential issues or opportunities, leading to better safety, efficiency, a...
Researchers at RMIT University have designed a new oral capsule that can deliver insulin and other protein drugs in a pain-free manner. The technology has shown promising results in pre-clinical studies, with good absorption rates for slow-acting insulin and potential for dosing over specific time periods.
Researchers developed molecular nanocages for selective siRNA delivery, showing promise in targeting cancer cells. The nanocage composition determines siRNA delivery efficiency, making it possible to tailor the system for specific cell types.
A highly pathogenic bird flu, H5N1, is spreading rapidly in the US, decimating wild birds and impacting poultry, with egg prices soaring. The study's findings highlight the need for unprecedented coordination to manage the spread of the disease, which may become endemic, posing risks to food security and the economy.
Researchers have discovered that manipulating Yes-associated protein (YAP) expression in liver progenitor cells can improve their ability to regenerate and repair liver tissue. This could lead to new treatments for chronic liver diseases.
A novel gene therapy approach decreases intraocular pressure in pre-clinical models of glaucoma. The treatment uses a viral vector to deliver instructions to cells, producing an enzyme that helps reduce fluid accumulation and pressure. This breakthrough holds promise for patients with glaucoma.
Penn State researchers found that complex and diverse supply chains can protect cities from shortages. The diversity of an ecosystem makes a system less vulnerable to natural disasters.
A new study reveals that the COVID-19 pandemic exacerbated racial inequalities in the US criminal legal system, with non-white individuals disproportionately receiving longer sentences. The study found that the population shift due to the pandemic increased the fraction of incarcerated Black and Latino people.
Researchers found that bad medical news can make patients more likely to choose brand name drugs over generics, resulting in increased healthcare expenditures. The study suggests that simply reminding patients of the equivalency of generic drugs via text message could improve their decision-making.
A study in Barcelona found that low temperatures increase sickness absence risk due to infectious and respiratory diseases. Women, young people, and those working in services sectors with non-manual tasks in indoor spaces are most affected. Sickness absences can last from two to six days after exposure to cold weather.
The University of Sheffield suggests policymakers offer financial incentives to encourage sustainable gardening practices, promoting greener gardens and boosting community health. Well-planted gardens provide habitats for wildlife, improve air quality, and reduce energy bills.
Researchers discovered that adding cell layers to corn bran can increase iron and zinc content by up to 35% and 15%, respectively. The technique also enhances anthocyanin production, a natural pigment in corn prized for its colorant properties.
Researchers identified the cause of Glutaric Aciduria Type I (GA-1), a metabolic disease common among people with Native American heritage. The toxic substances were found to accumulate in the liver and cross the blood-brain barrier, leading to neurological damage.
A multicentre prospective cohort study found that women using traditional Chinese medicine before and during pregnancy had a 2.1-times higher risk of congenital malformations compared to those without exposure. The study identified significant associations with early pregnant use and the use of two or more types of products.
Researchers discovered nanoscopic tunnels that connect precursor cells in the cerebellum as they mature into neurons. These tunnels enable molecular exchange and physical migration of pre-neuronal cells across layers, shedding light on brain connectivity and development.
A new HIV vaccine has shown improved ability to neutralize virus in preclinical tests, using nanoparticle display of multiple Env proteins. The vaccine design uses flexible sugar molecules called glycans to present self to the immune system.
New research reveals that millipede segments contain tiny bundles of legs, which appear as transparent protrusions before molting. This discovery could help understand how not only millipedes but also other arthropods grow and develop.
A strong sense of purpose in life promotes greater connectivity within the brain's Default Mode Network, which may help protect against cognitive decline. Middle-aged adults with a higher purpose in life show lower levels of brain burden and better cognitive performance.
Researchers have discovered the molecular structure of a new toxin class, Ssp, capable of entering and killing human cells. The discovery offers insights into developing targeted inhibitors to combat infections caused by Serratia marcescens, a pathogen with high antibiotic resistance.
The US prison population declined by 17% between March 2020 and July 2021, but the percentage of incarcerated Black people increased by almost a full percentage point at the height of the pandemic. This spike in proportion was temporarily reversed as courts reopened and new admissions slowed.
Researchers from HKUST and CityU developed a metasurface to generate time-varying OAM beams with a time-dependent phase profile. This allows for a higher-order twist in the envelope wavefront structure, increasing capacity for applications such as dynamic particle trapping and information encryption.
A new study published in Strategic Management Journal found that organizations serving more difficult customer needs tend to defer investment, while those addressing easier problems accelerate adoption of the same technology. The researchers emphasized the importance of letting customers drive strategy around adopting a technology, reg...
The concept of nature's chefs offers a new perspective on species interactions, highlighting the diversity of food-making and preparing species across the tree of life. This interdisciplinary approach aims to inform how people think about food across various disciplines.
A simple memory test predicted the risk of developing cognitive impairment in people with no thinking and memory problems. The study found that those at stages one and two were twice as likely to develop cognitive impairment, while those at stages three and four were three times as likely.
Researchers developed bottlebrush-like nanoparticles that deliver immunostimulatory drugs to tumors, provoking an immune response and slowing tumor growth. The approach avoids systemic inflammation, making it a potential solution for boosting immune system responses in cancer patients.
Researchers at UCR created quantum composites that exhibit functionality at a wide range of temperatures, offering potential applications in electronics, energy storage, and reflective coatings. The materials showed an unusually high ability to store electricity, with increased dielectric constant values.
A study found that sleeve gastrectomy decreases bone mineral density and strength in adolescents and young adults. Participants who underwent weight loss surgery lost significant amounts of weight and experienced reductions in abdominal fat tissue and muscle mass.
Researchers at Princeton University developed a new device called mmWall that can steer millimeter-wave (mmWave) signals to reach all corners of a large room. The device uses an accordion-like array of panels to reflect and refract radio waves, allowing for efficient beam steering and alignment with transmitters and receivers.
A study of over 300 extreme altruists reveals they share unselfish traits, not higher levels of empathy or agreeableness. Researchers found that their choices reflect a genuine value for strangers' wellbeing and communities.
A study found that young adults who experienced gunshot, stab, or assault wounds as children have significantly higher rates of post-traumatic stress disorder (PTSD) than the general population. Ten respondents screened positive for probable PTSD, and nearly 17% reported persistent symptoms related to their injury.
Individuals who experienced depression during pregnancy were more likely to be diagnosed with cardiovascular disease within two years after giving birth. The study found a significant higher risk of developing six major cardiovascular conditions, including heart failure and ischemic heart disease.
Researchers identify potential application of quantum compression in edge computing, which could save storage space and network bandwidth. Quantum compression, a new concept, is being explored as an enabling tool for edge applications, with classical techniques compared to quantum approaches.
A study by Penn State researchers found that organic beekeeping management is sustainable and supports high honey-bee survival and honey production, rivaling conventional methods. Organic and conventional management systems both increased winter survival by more than 180% compared to chemical-free management.
Researchers found that Carnivorous Sarracenia pitcher plants emit distinct odors to lure in specific groups of prey. The plant's volatile organic compounds significantly impact prey composition, highlighting the complex interactions between carnivorous plants and their environment.
Researchers at UNIGE discovered that natural opioids cannot enter cells, whereas therapeutic opioids can, leading to differences in physiological responses. The study's findings could help develop safer medications with improved efficacy and reduced side effects.
A new study found that dim light pollution can disrupt the dormant state of moths, leading to reduced survival rates. Researchers exposed urban and rural moth populations to artificial light at night, revealing a lack of adaptation in response to pollution.
A new study led by University of Nebraska-Lincoln researcher Kevin Smith explores the impact of polarized politics on mental and physical health. The research found that Americans' political anxiety increased before a major election, but decreased after, with specific groups experiencing lower levels of anxiety.
A recent study published in eClinicalMedicine found that eating walnuts on a regular basis can improve attention functions, fluid intelligence, and behavior in adolescents with ADHD. The research, led by the IISPV, suggests that following a healthy diet is crucial for cognitive development during adolescence.
A new group of DNA viruses, mirusviruses, has been discovered in marine plankton, linking them to both giant viruses and herpesviruses. The discovery reveals that the ancestors of herpes viruses once infected single-cell organisms, while the majority of mirusvirus genes share similarities with those of giant viruses.
The Tianzhou cargo spacecraft is a Chinese automated cargo spacecraft designed to support space station operation by transporting supplies. Its main tasks include transporting and storing supplies, controlling the orbit and attitude of the combined body, and supporting the development of space applications.
A new study found that high consumption of sugar-sweetened beverages was associated with an elevated risk of premature death and incidence of cardiovascular disease among people with type 2 diabetes. Drinking healthier beverages like coffee, tea, and plain water was linked to lower risk of dying prematurely.
Recent development in identification of oligomeric products from lignin depolymerization reveals understanding of formation causes and potential valorization routes. Common targeted products include monomeric phenols, aromatics, and cycloalkanes.
Nagoya University researchers have developed a poly(styrenesulfonic acid)-based PEM with an ultrahigh density of sulfonic acid groups, exceeding five times that of typical commercially available membranes. The new membrane exhibits a proton conductivity of 0.93 S/cm at 80°C under 90%RH, six times higher than Nafion or Selemion under th...
The study analyzed the growth and productivity of Botryococcus terribilis under different cultivation systems. Stress increased the production of lipids and hydrocarbons by 49% and 29%, respectively, while proteins decreased. The microalgae's metabolites have potential applications in biofuel synthesis, cosmetics, and food.
The NIH is conducting a clinical trial to evaluate the JYNNEOS mpox vaccine's safety and immune response in adolescents aged 12-17. The trial, launched at George Washington University, aims to determine if the vaccine can protect teens from this painful and sometimes deadly disease.
The AChemS meeting brings together scientists to understand the fundamental mechanisms of chemosensory systems and their impact on behavior. Key findings include presentations on learning and memory in the chemical senses and physiology of extraoral taste receptors.
A study by University of Cambridge researchers found that minority ethnic groups are less successful in applying to specialty training programmes in the NHS. Female applicants had a higher success rate overall, but certain specialities tend to appeal more to one gender or the other.
Researchers found that women with prediabetes after pregnancy had aberrations in their early pregnancy blood serum metabolomic profile, including higher concentrations of small HDL particles. These metabolic changes predicted prediabetes at postpartum and were associated with increased risk of type 2 diabetes.