Scientists have developed a new catalyst that enables the production of ammonia at lower temperatures, reducing energy consumption and potentially lowering global carbon emissions. The BaH2–BaO/Fe/CaH2 catalyst facilitates nitrogen gas adsorption, resulting in enhanced catalytic activity for ammonia production.
Researchers have developed a new type of nanoparticle that can efficiently deliver CRISPR/Cas9 components to the lungs, allowing for targeted gene editing. In mice studies, the particles delivered mRNA to up to 60% of lung epithelial cells, offering a promising approach to treating genetic diseases such as cystic fibrosis.
The research team developed a technology that can restore normal peripheral myelin protein 22 distribution in CMT1A cells using electric stimulation, which eliminates protein aggregation and induces myelination. This technology has potential for the development of an electronic medicine with minimal side effects.
A recent study published in PLOS Medicine found that increasing the proportion of non-alcoholic drinks on sale in online supermarkets can lead to a reduction in the amount of alcohol purchased. Participants who were exposed to more non-alcoholic drinks selected and purchased fewer units of alcohol compared to those with lower proportions.
Researchers discovered that theropod dinosaurs, including T. rex and Velociraptor, had scaly lips similar to those of lizards, contradicting popular depictions. The study found that dinosaur teeth were not unusually large and were comparable in size to modern lizard teeth when adjusted for skull size.
Researchers found that preserving the meniscus with sutures is more effective in protecting cartilage from future damage in younger patients. Meniscectomies, which remove more than half of the meniscus, were more likely to progress cartilage degeneration.
Two independent studies reveal neutrophils' crucial role in cancer immunotherapies, showing promise for new treatments. Neutrophils surge in tumors responding to immunotherapy, playing a key role in eliminating cancer cells that evade T-cell recognition.
Researchers found that neutrophils can be pro- or anti-tumour depending on their surface markers, and those fighting tumours share cytotoxic power with neutrophils in bacterial infections. Blocking these anti-tumour neutrophils eliminates treatment benefits.
For the first time, scientists have observed nanoparticles forming crystals with unprecedented clarity. The study used optimized liquid-phase transmission electron microscopy to capture the self-assembly process of thousands of nanoparticles. This breakthrough could lead to designing new materials for electronic applications.
Professor Jong-Sung Yu's team developed a low-temperature method to synthesize highly graphitized carbon supports, increasing the lifespan of hydrogen fuel-cells. The new method introduces high graphiticity at relatively low temperatures, enhancing fuel-cell performance.
A new mechanochemical recycling method recovers up to 70 percent of lithium from battery waste, making it inexpensive, energy-efficient, and environmentally compatible. The method uses aluminum as a reducing agent and can be applied to various cathode materials.
A team of researchers emphasizes the need for science-backed policies that consider children's developmental vulnerabilities in the digital world. They propose a multidisciplinary approach to develop regulations that address timely questions about digital platforms and their impact on children.
Researchers at EPFL have developed a novel solution for wearable assistive technologies by creating fiber-like pumps that can generate high pressure and flow rate. These pumps can be integrated directly into clothing, allowing for silent, vibration-free operation and requiring only a palm-sized power supply.
Researchers developed a way to study living cell dynamics using optically trapped nanodiamond particles as intracellular sensors. They demonstrated the ability to measure magnetic noise within single leukemia cells.
The article summarizes current status and future trends of forest understory vegetation biodiversity, regeneration, biomass, nutrient content, and interactions with overstory trees. It proposes focusing on understory-Canopy tree interactions and plant-soil mechanisms driven by climate or environmental factors.
A recent study found that nearly 64% of US youth experience eye problems and need glasses, but over half are deterred by appearance concerns. Researchers suggest making stylish, affordable glasses for young people to improve access to eyewear.
Researchers have developed a new host material that enhances the efficiency of organic light-emitting diodes (OLEDs) by reducing concentration quenching and increasing thermally activated delayed fluorescence. This breakthrough could lead to improved displays, lighting, and medical treatments.
A new study reveals that patients with blood cancers experience significant improvement in their reported well-being after receiving CAR T-cell therapy. The therapy not only improves physical symptoms but also anxiety and depression symptoms.
A remarkably well-preserved sabertooth cat skull found in southwest Iowa offers clues about the iconic Ice Age species' ecology, diet, and habitat. The researchers believe it belonged to a male subadult weighing around 550 pounds when it died.
A new AI tool, CLEAN, can predict enzyme functions based on amino acid sequences, outperforming leading state-of-the-art tools in accuracy and reliability. The tool was developed using contrastive learning and verified experimentally with both computational and in vitro experiments.
A team of researchers has observed nanoparticles self-assembling and crystalizing into solid materials in real time, revealing the growth process at nanometer resolution. The findings have implications for designing new materials, including thin films for electronic applications.
Researchers propose conjugating a cell-penetrating peptide to oxaliplatin to overcome chemotherapy resistance in colorectal cancer. The new approach reduces platinum accumulation in tumour microenvironment and healthy tissues.
Rice University's assistant professor of computer science, Todd Treangen, has been awarded a $599,943 National Science Foundation CAREER Award to develop a comprehensive computational platform for detecting yet-unseen microbial pathogens. The project aims to characterize previously unseen pathogens that could pose a risk to humans.
Researchers have presented an overview of recent progress in moiré photonics and optoelectronics, highlighting the emergence of novel quantum phenomena and their potential applications. Moiré superlattices introduce a new paradigm for engineering band structures and exotic quantum states.
Researchers have discovered that Shigella bacteria can infect humans but not mice due to differences in the shape of a key protein, gasdermin-B. The protein has six different forms, and some isoforms cause cell death while others do not, explaining why Shigella is unable to infect mice.
A specialized mRNA translation circuit controlled by protein RBPMS determines the competence for heart formation in human embryonic development. The study provides a better understanding of human cardiac development and reveals potential molecular targets for therapeutic interventions.
Researchers develop unique method to enhance extreme ultraviolet laser power by exploiting dark-autoionizing states, increasing conversion efficiency by over ten times. This breakthrough enables studying ultrafast dynamics of dark autoionizing states at the femtosecond timescale, with potential applications in quantum technologies.
Researchers at Tel Aviv University recorded and analyzed plant sounds emitted under stress, identifying specific identifiable sounds. The study suggests that plants may communicate with other plants and animals through these sounds.
The American Thoracic Society has issued a statement recommending the elimination of race and ethnicity in the interpretation of pulmonary function test (PFT) results. The new approach uses an average reference equation, which shows superiority over race-specific equations for assessing overall prognosis and impact of tobacco smoke exp...
Researchers at Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively breaks carbon-hydrogen bonds, suggesting ways to engineer it for producing desired products. The detailed structure reveals how the enzyme operates under ordinary conditions and produces few unwanted byproducts.
A study reveals racial and ethnic disparities in smoking initiation among young adults with different education levels. Black young adults tend to have lower smoking prevalence and older age of smoking initiation than white counterparts.
Scientists have discovered the origin of congenital coronary fistulae, a condition where abnormal connections form between blood vessels and heart chambers. This study may help improve early diagnosis and treatment of this condition, which affects up to 0.2% of patients undergoing medical examination.
A recent study found that genetic risk scores are more predictive of Alzheimer's disease in adults over 65 than age. The study used machine learning models to rank risk factors, including household income, which emerged as an important risk factor. The findings suggest considering genetic information when working on Alzheimer's disease.
Researchers have developed an effective method to remove toxic hexavalent chromium from wastewater using photocatalytic technology. The new approach utilizes hourglass-type phosphomolybdate-based crystalline photocatalysts, which show a wide light absorption ability and band structure necessary to reduce heavy metal ions.
Scientists successfully observe and quantify a two-dimensional electron gas at the semiconductor interface, enabling control of its performance. This breakthrough leads to the development of high-performance high-frequency/power devices with improved interface analysis and control.
A new study by Intermountain Healthcare and Stanford University found that overprescribing antibiotics for upper respiratory infections causes significant patient harm. Researchers analyzed 51 million patient encounters and found that one in 300 patients experienced severe side effects, such as diarrhea or candidiasis, after receiving ...
The detection of GRB 221009A marks the most energetic gamma-ray burst ever observed, with a luminosity surpassing that of entire galaxies and hundreds of billions of stars. The event was followed up by space-based telescopes, including the James Webb Space Telescope, which provided insight into its properties.
Researchers found that a specific type of immune cell can detect and eliminate senescent cells in the skin by targeting human cytomegalovirus antigens. This discovery suggests a potential therapeutic approach to eliminate aging cells, which could have applications in cancer, fibrosis, and degenerative diseases.
Studies found that certain T cells in human blood can produce acetylcholine, regulating blood pressure and inflammation. Higher levels of these immune cells were associated with reduced risk of death in seriously ill patients.
A recent study published in Nature Communications reveals that Earth's anisotropic inner core structure is driven by the dipole geomagnetic field. The researchers found that hexagonal-close-packed (hcp) Fe-H alloy exhibited both seismic anisotropy and H-ion diffusion anisotropy under high pressure-temperature conditions.
A study explores how people remain productive and find meaning in later life, revealing key lessons from experts like John Cook, Judy Woodruff, and Chris Labenz. The research highlights the importance of following one's passion and not retreating to a conventional retirement lifestyle.
Scientists have found that glycine, an amino acid, can deliver a 'slow-down' signal to the brain, influencing major depression and anxiety in some people. The discovery improves understanding of the biological causes of major depression and could lead to new, faster-acting medications.
Researchers from Boston University School of Medicine have found that ETEC pili are fine-tuned for their preferred microenvironment, allowing the bacteria to cause disease. By understanding how pili work, scientists may develop new therapeutics that target only disease-causing bacteria, leaving beneficial microbes intact.
A new study highlights the importance of mutual trust between citizens and authorities in crisis situations. Data from the COVID-19 pandemic confirms that trust in fellow citizens is unlikely to reduce compliance with restrictions.
A team of international researchers has uncovered a more complex history of early horses in North America, suggesting they may have spread faster and earlier than previously thought. The study, published in Science, used archaeozoology, DNA sequencing, and Indigenous oral traditions to find that Native American communities were likely ...
A genome-wide association study identified a new quantitative trait locus, STP1, encoding a Sugar Transporter Protein that alters soluble solid content. Knockout of STP1 led to decreased SSC in fruits, highlighting ZAT10-LIKE transcription factor's role in regulating sugar transporters.
A new study reveals that theropod dinosaurs had their large teeth completely covered by thin, scaly 'lips' when their mouths were closed. This finding challenges long-held depictions of these iconic predators and could have significant implications for our understanding of dinosaur dental anatomy and biomechanics.
Researchers from Juntendo University found that sialylated mucins secreted by conjunctival goblet cells encapsulate allergens, protecting the eye from allergic conjunctivitis. Mice with intact St6galnac1 gene showed reduced antigen response and better protection against allergies.
Researchers found that bats lose their hearing in old age due to exposure to high noise levels in their colonies. The study suggests that bats may have evolved adaptations to cope with these noisy environments, which could provide insights into human age-related hearing loss.
Researchers at Tokyo Institute of Technology developed a novel visible light-driven single transition metal catalyst that combines high light harvesting abilities and broad applicability. The SFI-Rh(I) complexes overcome previous limitations, enabling versatile photocatalytic reactions with increased stability.
The Norwegian University of Science and Technology has been awarded a €2.5 million grant from the European Research Council to investigate how species can survive in a changing environment. The project aims to develop rules for preventing species extinction and studying adaptation to environmental changes.
Researchers have created a new tool, EN-TEx, to analyze genetic mutations and predict disease risk. The catalog of allele-specific variants provides rich data for accurate personal genomics, enabling scientists to study the effects of genetic mutations in tissues that are difficult to obtain without surgery.
The PROMISE II clinical trial showed that LimFlow therapy enabled 76% of patients to avoid amputation and experience wound healing. This minimally invasive procedure bypasses blocked arteries in the leg and rushes blood back into the foot through the veins, providing a unique alternative to major amputation.
High blood pressure in children is a significant health concern, potentially leading to cardiovascular problems in adulthood. The American Heart Association recommends monitoring blood pressure levels and implementing lifestyle modifications such as a healthy diet, regular physical activity, and weight management.
Research found that STI and HIV testing rates dropped significantly in March 2020, while positive test rates rose. The decline was likely driven by public health recommendations limiting in-person visits during the pandemic.
Researchers at Oregon State University have created a new model for evaluating potential cervical cancer drugs. The study, led by Kaitlin Fogg, enables the simultaneous and rapid testing of multiple drug compounds, opening the door to large-scale screenings that can uncover new therapies and personalized medicine options.
Researchers predict that layered electronic 2D semiconductors can host a quantum phase of matter called the supersolid. A solid becomes 'super' when its quantum properties match those of superconductors, simultaneously having two orders: solid and super. The study reports the complete phase diagram of this system at low temperatures.
Researchers investigated bamboo paper's moisture absorption behaviour under different ageing patterns, finding that ageing doesn't alter water adsorption but reduces effective adsorption sites. Storage humidity conditions around 50% RH are recommended to maintain the paper's stability.
The study found that downregulation of angulin-1/LSR leads to increased claudin-2 expression and altered cell metabolism in human lung adenocarcinoma cells, promoting malignancy. Researchers identified AG1478 and EW-7197 as potential therapeutic agents.
A large population study reveals that common cancer symptoms are pervasive across all types of cancer and sociodemographics, with higher symptom burdens among patients with lung, gastrointestinal, and gynecologic cancers. The study highlights the importance of prioritizing symptom management in patients who need or desire treatment.