Researchers found preserved molecular fragments of the pigment phaeomelanin in 10-million-year-old frog fossils, which could help reconstruct ancient animal colors. This discovery may be a first step towards understanding the evolution of toxic phaeomelanin.
Researchers analyzed an ancient stalagmite from a Grand Canyon cave to understand the relationship between global warming and the strength of the North American Monsoon. They found that increasing moisture during the early Holocene period may lead to greater summer rainfall on the Colorado Plateau and intensifying monsoons in the future.
Scientists propose that pulsars could detect dark matter by observing a subtle additional glow. If axions are produced in strong electromagnetic fields around pulsars, they could convert into observable light.
Researchers discuss lurbinectedin as a method to treat neuroendocrine tumors (NETs), with encouraging results from phase II basket studies demonstrating activity in platinum-sensitive relapsed SCLC and other malignancies. Lurbinectedin's mechanism of action involves inhibiting oncogenic transcription, promoting apoptosis and cell death.
A new study led by UCL researchers finds that integrated health care for chronic high-burden conditions like diabetes and hypertension is feasible and cost-effective. The study showed that integrated care was associated with high levels of retention in care, no adverse effect on viral suppression among people with HIV, and cost-saving ...
A Swedish study finds that fathers' parental leave is associated with a 34% decrease in alcohol-related hospitalizations among fathers, as well as smaller decreases over time. The policy change led to increased fathers' use of parental leave, which may explain the observed health benefits.
A Rutgers study found diverse firearm owning communities across five states, including varying levels of risk for injury and death. States like Mississippi and Texas showed more dangerous behavior, while New Jersey residents were less likely to grow up in homes with firearms or use them unsafely.
A University of Basel study reveals that high levels of arginine drive metabolic reprogramming to promote tumor growth. The findings suggest targeting the specific arginine-binding factor for effective liver cancer treatment.
Researchers developed a simple, one-step method for creating large-area liquid crystal microlens arrays (LC-MLAs) with high focusing quality. The LC-MLAs demonstrate polarization-dependent, electrically tunable properties, allowing for adjustable focal length and image depth control.
A team of New York University computer scientists created a neural network that can explain how it reaches its predictions, shedding light on the intricacies of RNA splicing. The breakthrough reveals how a small, hairpin-like structure in RNA can decrease splicing and provides new insights into the transfer of genomic information.
A recent study by UTHealth Houston found that the offspring of adolescent and young adult women with a history of cancer face a higher risk of birth defects. The study examined 6,882 offspring ages 12 months and younger and found an increased risk of specific types of defects in the offspring of women with a history of cancer.
A survey of 1,373 physicians reveals a growing trend of physician burnout, which could compromise patient care. The study highlights the urgent need for solutions to address this critical issue affecting the healthcare sector.
A team of scientists has successfully caught fast-moving hydrogen atoms within ammonia molecules using ultrafast electron diffraction. They observed the motion of hydrogen atoms and captured the associated change in the molecule's structure as it evolved, providing insights into proton transfers.
Researchers developed a wearable device to track bipolar disorder patients' skin electrical activity, detecting manic and depressed phases. The study aims to improve diagnosis and treatment with personalized, rapid interventions.
A team of researchers from KIST and KAIST developed a soft robotic gripper that can lift objects weighing over 100 kg using only 130 grams of material. The gripper's woven structure is inspired by textiles and achieves high performance, cost-effectiveness, and process efficiency.
A new study analyzing over 3,000 women found that more than half of rape survivors had no detectable anogenital injuries, despite being examined by experts. The research challenges the myth that physical violence is always present in rape cases, highlighting the need to support survivors and challenge cultural attitudes towards reporti...
A Texas A&M University team, led by Dr. Terri Pantuso, is developing an open-access writing curriculum to prepare high school students for college-level English courses. The project aims to improve TSI readiness and incorporates digital instructional tools, AI-powered learning resources, and intervention strategies.
Osaka Metropolitan University scientists have developed a super-efficient laser light-induced detection method that reduces detection time from hours to minutes. The technique allows for ultrafast and ultrasensitive measurement of biological nanoparticles, including exosomes, with diameters of 50–150 nm.
Researchers discovered a non-invasive eye exam that can detect early signs of cognitive decline and cerebral small vessel disease, a major contributor to vascular dementia. The study found connections between altered retinal blood flow and changes in brain structure associated with the condition.
A team of neuroscientists has identified specific neurons in the auditory cortex that only respond to sounds that violate expectations, sending a message that a mistake has been made. These 'prediction-error neurons' may play a vital role in learning how to speak or play musical instruments.
A new study led by researchers at the University of Tennessee, Knoxville, proposes a way to improve the effectiveness of conservation funding by giving organizations more freedom to allocate funds. By doing so, the team found that conservation projects can offer a high return on investment and make a greater impact on species protection.
A study published in Gastroenterology validated pyrvinium as a potential preventative treatment for stomach cancer. The drug induces cell death in precancerous lesions by targeting specific stem cells through dual MEK/ERK and STAT3 inhibition, suggesting lower adverse effects on tissue regeneration.
Researchers have observed a unique stage in the development of planetary systems by detecting a smooth protoplanetary disk around the young star DG Taurus. This discovery provides new insights into the conditions at the start of planet formation, challenging current theoretical expectations.
Researchers have pinpointed the molecular mechanism by which a large portion of BRCA1 mutations cause cancers in women. The study found that the E3 ligase activity of BRCA1 is crucial in several stages of DNA repair and tumor suppression, reinterpreting previous findings.
Researchers have discovered that gamma delta T cells are crucial to preventing bowel cancer. The study found that patients with higher concentrations of these immune cells had better outcomes and improved survival rates.
The Nuclear Science Advisory Committee has released a new long range plan, prioritizing the capitalization of substantial research investments to advance discovery in nuclear physics. The plan recommends increasing the research budget and continuing effective operation of national user facilities.
A new study has identified two main pathways involved in Alzheimer's disease, with one acting through amyloid and tau proteins and the other based on immune system reactions. The research also found that certain genes have opposite effects in men and women, suggesting a need for further investigation.
Researchers have developed high-speed and high-responsivity photodetectors on a thin-film lithium niobate platform, achieving a 3-dB bandwidth of 110 GHz and responsivity of 0.4 A/W at 1550-nm wavelength. The devices demonstrate potential for ultra-high-speed optical communications and multi-function integrated quantum photonics.
New study uses flume-tank experiments to observe changes in sediment deposits and current velocities, revealing insights into past ocean currents. The findings have huge application potential for understanding climate, pollution transport, and benthic ecology.
A groundbreaking study reveals that linear defects in diamond can spread at speeds exceeding the speed of sound, which could impact our understanding of material strength, failure, and manufacturing. This discovery may lead to new insights into earthquake ruptures, structural failures, and precision manufacturing.
Researchers at IBS Center for Quantum Nanoscience created a novel electron-spin qubit platform assembled atom-by-atom on a surface, demonstrating ability to control multiple qubits. This breakthrough enables application of single-, two-, and three-qubit gates.
Researchers at Scripps Research have identified promising cancer drug targets by combining precise genome engineering and protein activity profiling. They used base editing to alter thousands of possible drug targets, then integrated the data with chemical proteomic information to pinpoint hundreds of potential targets.
Researchers at BYU and Duke University found that AI can improve conversation quality and promote civil dialogue in online interactions. By using AI-generated rephrasings of users' messages, participants exhibited greater willingness to listen to opposing viewpoints and reported higher conversation quality.
A study found that socio-economic factors, school type, and location greatly impact access to bilingual education in Andalusia. Public schools offer bilingual education to a much lesser extent than semi-private or private ones. The researchers propose reconfiguring areas of influence, changing admissions models, or encouraging low-inco...
A new study reveals that changing nutrient use can reprogram immune cells, potentially treating cancer and infections. By blocking choline metabolism, researchers found a 'tremendous reprogramming of the immune profile' in mice, suggesting this knowledge could lead to novel therapies.
A study of 132 people found that classical music induces synchronisation in physical responses among concert audience members. Personality traits such as agreeableness and openness are associated with increased likelihood of synchronisation. Synchronisation was observed in movement, heart rate, breathing rate, and skin conductivity.
The study successfully observed the chiro-optical effect at the nanoscale, demonstrating the ability to analyze the chiral structure of matter using light. Different images were obtained when illuminating with right- or left-circularly polarized light, clarifying that local handedness can be distinguished.
Recent advances in ancient DNA have greatly expanded our knowledge of evolutionary history, including the study of non-European regions. Finer-scale investigations can provide insights into past histories of neglected communities and inform conservation efforts.
Researchers mapped the global supply chain of cigarettes from farm to factory, revealing a direct link between industry operations and interference with public health policies. Countries with higher numbers of transnational tobacco leaf companies experience weaker tobacco control measures.
A new study published in the Journal of Marketing presents the Comparative Method of Valuation as a more accurate way to measure customers' willingness to pay. The study finds that existing methods can provide vague and inaccurate results due to their inability to capture relevant comparisons or context.
Researchers have discovered a way to make solar hydrogen production economically viable by co-producing high-value chemicals like methylsuccinic acid. By coupling the photoelectrochemical (PEC) process with hydrogenation, the cost of hydrogen drops significantly, making it competitive with fossil gas.
A Phase IIIb study published in the New England Journal of Medicine found that esketamine nasal spray achieved higher remission rates (27.1%) compared to quetiapine extended-release (17.6%) in patients with treatment-resistant depression, indicating its potential as a targeted therapy for this population.
Researchers using H.E.S.S. observatory in Namibia have detected the highest energy gamma rays ever from a dead star called a pulsar, with energies reaching up to 20 tera-electronvolts. This observation challenges our previous knowledge of pulsars and requires a rethinking of how these natural accelerators work.
Researchers at Washington State University have made a groundbreaking discovery about the Fischer Tropsch process, a key step in converting coal, natural gas, and biomass into liquid fuels. The team found that the process exhibits self-sustained oscillations, which can be harnessed to enhance reaction rates and product yields.
A large epidemiological study found a higher incidence of stomach paralysis, pancreatitis, and bowel obstruction in patients taking GLP-1 agonist medications for weight loss. The study, published in JAMA, highlights the need for updated warning labels to inform patients of these potential risks.
A new study finds that racial and ethnic disparities in chronic pain after acute traumatic injury are driven by differences in the nature of and health care response to acute injuries. Factors associated with disparities include mechanism of injury, severity of injury, pain in the hospital, and length of hospital stay.
A new UC Davis study investigates the complex mix of attitudes and concerns about the state of democracy in the US. While most respondents reject political violence altogether, some believe it is usually or always justified to advance political objectives.
A new generative AI model enhances clinical accuracy and textual quality of chest radiograph reports, surpassing traditional methods like teleradiology. Its implementation could enable timely alerts for life-threatening conditions, aiding imaging interpretation and documentation.
Researchers at Tulane University discovered that prior exposure to Cytomegalovirus (CMV) significantly reduces the risk of birth defects and miscarriage during pregnancy. The study found that pre-existing immunity effectively limits transmission and protects against associated birth defects.
Ancient human footprints discovered in White Sands National Park have been confirmed to be over 20,000 years old. Multiple independent age estimates from radiocarbon and optically simulated luminescence methods support the previous study's claims, showing humans inhabited southern North America during the Last Glacial Maximum.
The Endangered Landscapes & Seascapes Programme will support up to eight new sea restoration projects across Europe. This funding aims to create resilient ecosystems that benefit nature and people. The programme's third phase will focus on expanding large-scale restoration projects, including those focused on Europe's seas.
A Dartmouth-led study found that tweets featuring K-pop group BTS generated 111 times more virality than similar tweets without the artist's name. This highlights the power of entertainment in driving public health messages and bridging cultural divides.
Researchers investigated whether marketing can influence men's perceptions of vegan food. They found that while short-term interventions may not change consumption habits, long-term approaches could lead to improved attitudes towards veganism.
Researchers at Shibaura Institute of Technology developed a cellulose-based thickener to reduce environmental risks associated with liquefied stabilized soil. The thickener prevents bleeding, loss of fine particles, and unwanted settling, while maintaining soil strength.
Researchers found that seabird couples with compatible personalities have better parenting success and lower divorce rates. This is because they can make informed decisions together when one parent is away finding food at sea.
A study of 4,070 insured adults with diabetes found persistent disparities in poor glycemic control, even after adjusting for social, healthcare, and behavioral factors. The research highlights the need for further investigation into the barriers contributing to these disparities.
A team from Michigan State University discovered that, on a warming planet, plants like oaks and poplars will emit more of a compound called isoprene, exacerbating poor air quality. This finding has significant implications for understanding the impact of climate change on air pollution.
Researchers at the University of Seville have developed a more efficient configuration for proton-exchange membrane fuel cell batteries, increasing their performance by up to 10%. The new design outperforms other options and reduces energy consumption, making it suitable for use in electric vehicles.
A recent study found that animals in the Greater Kruger National Park react with alarm to hearing human voices, fleeing waterholes and abandoning their habitat. The researchers used custom sound systems to compare the fear response of mammals to humans versus lions.
The Heidelberg team developed a hybrid metal-halide perovskite semiconductor with high photoluminescence quantum efficiency and strong chirality, generating bright circularly polarised light. This breakthrough material combines the best of inorganic and organic semiconductors, enabling applications in optoelectronics and information pr...