A collaborative study reveals distinct mechanisms of plant and animal response to climate change in their life-cycle phenology. The research team compiled a global phenological dataset, showing that plants' late-season phenophases advance more significantly than animals', potentially due to increased plant productivity.
Adenosine deaminase 2 (ADA2) controls TLR9 activation in plasmacytoid dendritic cells, influencing responses to viral infections and cancer. Its extracellular form regulates myeloid cell polarization and cytokine secretion.
Researchers at Tel Aviv University discovered the brain actively prevents learning both types of memory, leading to confusion. The brain prioritizes one type of learning over the other using a strategy to resolve conflicts.
Biophysics Reports published a landmark study celebrating 30 years of Ca2+ spark research, revealing new insights into calcium signaling mechanisms. The review explores the digital principle of cell signaling, paving the way for further exploration in understanding and treating diseases.
The proposed algorithm aggregates tasks with similar characteristics to improve task completion quality. It also reduces travel distances by developing a path-planning approach, achieving greater performance as the number of tasks increases.
Alzheimer's disease is characterized by amyloid plaques and neurofibrillary tangles, with genetic predispositions and aging contributing to its development. Early intervention and biomarkers are crucial for diagnosis and treatment.
Researchers are discovering selenium nanoparticles' potential in cancer prevention, inflammation reduction, and tumor treatment through their ability to activate the immune system and reduce inflammation. SeNPs are also being explored as vaccine adjuvants to improve immune cell activation and boost cancer vaccine efficacy.
This research enhances understanding of βAR signaling and its implications for heart health, highlighting the protective effects of β2AR. Targeting βAR pathways may develop novel therapies for heart diseases by leveraging compartmentalization.
The 26th Nagoya Medal of Organic Chemistry will be held on January 24th, 2025, with gold medalist Professor Alois Fürstner presenting lectures on catalysis and metal-carbene chemistry. Silver medalist Professor Masayuki Inoue will discuss total synthesis of highly oxygenated natural products.
Neuroscientist Inga Neumann discusses groundbreaking research on oxytocin, a neuropeptide that shapes social behavior and emotional responses. Her work has significant implications for treating social anxiety disorders and understanding stress resilience.
Research found that pectin lyase PsPL1 induces soybean cell death and immune responses, bypassing regulation by LRR proteins. Degradation products of pectin oligosaccharides activate plant resistance through recognition by distinct cell membrane receptors.
APTE 2025 focuses on emerging solutions to address transportation challenges while promoting inclusivity, reliability, and sustainability. The conference invites submissions on a broad range of topics related to transportation and the environment.
A new bone regeneration scaffold, Qx-D, shows promise in treating infected bone defects by exhibiting broad-spectrum antibacterial activity against various bacteria. The scaffold also supports the adhesion and differentiation of key cell types involved in bone regeneration.
Researchers have proposed a novel strategy utilizing ICT between D-A molecules to enhance IR photodetection. The approach leads to elevated EQE in the polaron absorption region and strong low-energy subgap absorptions, offering a pathway to high-performance next-generation IR photodetectors.
A novel disturbance rejection optimal guidance method has been proposed to enhance precision landing performance of reusable rockets. The method combines adaptive optimal steering and disturbance attenuation, allowing for improved accuracy and reduced propellant usage.
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Researchers from Korea University have developed a groundbreaking technique to transform fibroblasts into mature cardiomyocytes, holding promise for regenerative medicine in treating cardiovascular disease. The method combines fibroblast growth factor 4 (FGF4) with vitamin C to accelerate cell maturation and enhance function.
Researchers unveil groundbreaking wearable technology for continuous cardiac activity monitoring, addressing limitations of traditional stethoscopes and offering transformative solutions for early detection and effective treatment of cardiovascular conditions. The study highlights key innovations in sensor types, material innovations, ...
A cutting-edge study introduces imine-linked COFs with exceptional properties for advanced technologies and sustainability. These materials offer unprecedented opportunities for gas storage, separation, catalysis, and optoelectronics, promising breakthroughs in environmental solutions and energy-efficient technologies.
Researchers found that bumetanide treatment normalizes neonatal social communication in newborn pups with the fragile X mutation, but reduces post-pubertal social interaction. The study suggests stage-specific effects on social development and raises questions about timing and dosing of bumetanide for targeted interventions.
Icelandic researchers are searching for forgotten pieces of history in ancient, reused parchments. The study focuses on palimpsests, texts written over old manuscripts, which were common in the Middle Ages across Europe and particularly widespread in Iceland.
A new scanning method allows experts to see the effects of treatment on lung function in real time and enable early identification of decline. The scan method enables researchers to quantify the degree of improvement in ventilation when patients have a treatment, which could be valuable in clinical trials.
A POSTECH research team developed a groundbreaking strategy to enhance LLO material durability, extending battery lifespan by up to 84.3% after 700 cycles. The breakthrough addresses capacity fading and voltage decay issues.
A research team at Pohang University of Science & Technology developed a technology that visualizes the deformation of 'serpentine' structures in real-time through color changes. This innovation eliminates the need for complex nanofabrication processes, providing actionable design guidelines for optimizing these structures.
Researchers found that fruit flies have stolen a toxin-producing gene from bacteria to defend against parasitic wasps, which can turn fly larvae into surrogate wombs for baby wasps. This discovery highlights the importance of horizontal gene transfer in animal evolution and suggests it may be more common than previously thought.
Researchers developed AI-driven therapeutic platform mimicking viral structures to deliver therapeutic genes to target cells. The innovative approach achieved precise symmetrical structures and effectively delivered payloads, paving the way for breakthroughs in gene therapies and next-generation vaccines.
PPPL researchers will lead two collaborative projects involving national labs, academic, and industry partners to advance microelectronics and sensors. The projects aim to create a science-based plasma-processing toolbox for next-generation semiconductor device manufacturing processes.
NASA has partnered with Firefly Aerospace to deliver UCF's Lunar Vulkan Imaging and Spectroscopy Explorer (Lunar-VISE) payload to the Moon's Gruithuisen Domes. The mission aims to investigate the mysterious silica-rich volcanic features and gather data on lunar regolith for future exploration.
The journal Medicinal Plant Biology has been successfully indexed in Web of Science's ESCI, enhancing article visibility and positioning them for potential indexing in higher-level databases. This milestone reflects the journal's high quality and growth prospects, promoting open-access content to a broader academic community.
City of Hope researchers and collaborators have developed a new method to facilitate encoding numerous features in T cells, allowing for the simultaneous targeting of multiple tumor escape mechanisms. The 'zip-sorting' system doubles genetic information capacity, enabling improved anti-tumor activity and longer-lived T cells.
Researchers discovered that RNA modifications enable fungi to evade drug treatment and become temporarily resistant. This finding could lead to better treatment options against fungal infections by targeting specific RNA modification mechanisms.
Researchers found a specific magnesium concentration range where DNA wraps around polyphosphate-magnesium ion condensates, forming flexible structures. This discovery could lead to new methods for tuning cellular responses and has potential applications in translational medicine.
The NBS Global Leaders programme offers a semester-long exchange at UC Berkeley, $10,000 final-year project funding, and internship opportunities locally and globally. Students will also receive structured mentorship, industry workshops, and coaching to develop leadership skills.
Researchers used bioacoustics to identify individual leopards through their vocalisations, which proved 93.1% accurate in identifying each leopard's distinct 'sawing roar'. This technique has the potential to aid in population estimates and mitigate human-wildlife conflicts.
Early treatment with TNF inhibitors has been shown to prevent complications in kids with Crohn's disease, reducing the risk of perianal fistulas by 82%. The study found that anti-TNF drugs are specifically effective in preventing these debilitating complications, making them a recommended first-line therapy.
Researchers developed a non-invasive way to assess fat composition around the heart using magnetic resonance imaging. This technique may help doctors identify patients at greatest risk for cardiac problems and predict treatment outcomes.
A recent study published in Psychological Science in the Public Interest explores how framing effects shape our thoughts, feelings, and actions. The authors discuss various linguistic techniques, such as war metaphors, that can significantly impact our perceptions of complex issues like cancer.
A new study found that a unique population of large fish-eating herring has evolved in the Baltic Sea, exhibiting faster growth rates and lower levels of pollutants. These herring have adapted to the brackish water by switching from plankton-eating to a fish diet, with potential benefits for human consumption.
A study by the American Academy of Neurology found no association between COVID-19 infections and worsening multiple sclerosis (MS) symptoms or disability. Researchers followed 2,132 adults with MS over 18 months and found similar increases in symptom severity for those with and without COVID-19 infection.
A new study found that emergency department physicians differ in their likelihood of hospitalizing patients, with those who admit more patients being discharged sooner but not less likely to die. The study suggests that differences in physician decision-making drive these variations, rather than patient health.
The study highlights the need for targeted incentives to expand hospital-at-home programs to smaller, rural, and non-teaching hospitals. The research found that adoption of these programs remains concentrated among larger, urban, not-for-profit, and academic hospitals.
The American Academy of Neurology outlines 12 factors that influence a person's brain health at all stages of life. By discussing these factors with your neurologist or primary care physician, they can provide advice and resources to help you improve your brain health.
Researchers have developed a novel eye drop treatment for dry age-related macular degeneration, leveraging the inflammatory signaling pathway of Toll-like receptors to inhibit AMD pathogenesis. The treatment demonstrated retinal cell protection and reduced retinal degeneration in mice with induced dry AMD.
Researchers discovered that individual prey follows simple decision-making rules, leading to complex collective escape patterns. The 'fountain effect' allows sardines to outmaneuver marlins, but predators can also exploit this defense mechanism by attacking from the side or back.
The US Department of Energy is investing $179 million in three Microelectronics Science Research Centers to develop next-generation microelectronics designed for extreme environments. PNNL will lead projects on neuromorphic computing, EUV lithography, and heterogeneous computing.
Researchers at Osaka University developed a dynamic facial expression synthesis technology using waveform movements, allowing androids to exhibit mood changes and convey emotions. This innovation enhances emotional communication between humans and robots, potentially leading to more natural interactions.
A Cornell University team has made a groundbreaking finding in apple cells, demonstrating that a structural cell protein directly influences DNA transcription into RNA. This breakthrough has significant implications for understanding gene expression in all nucleus-containing cells, including humans.
The S2Cool project aims to design and develop a Novel Indirect Evaporative Cooler (NIEC) that addresses the constraints of current IEC systems through simplified design and optimised airflow. The technology has the potential to deliver transformative benefits, including up to 65% energy savings and significant reductions in CO2 emissions.
A Rutgers-led study of heart-attack patients with anemia found that more liberal blood transfusions can save lives at six months. The analysis combined data from four clinical trials involving 4,311 patients, suggesting a reduced risk of death at six months with more transfusions.
A new CU Boulder study found that residents of surviving homes in the area reported physical symptoms, including headaches and sore throats, attributed to poor air quality six months after the Marshall Fire. The study also found that hazardous gases lingered for weeks inside smoke- and ash-damaged homes.
Researchers found that defects in the planar cell polarity pathway play a significant role in the pathogenesis of yellow nail syndrome (YNS). The study identified the CELSR1 gene as a principal candidate disease-causing gene with autosomal recessive inheritance.
Researchers created a whole-brain atlas to visualize regions of the brain connected to V1 interneurons, a group of cells necessary for movement. The findings provide a framework to further understand the anatomical landscape of the nervous system and how the brain communicates with the spinal cord.
A study by the National Center for Supercomputing Applications aims to create personalized nutrition plans based on an individual's unique gut microbiome. The researchers used Illinois Computes to analyze metabolomic data and develop a database of metabolites that can help diagnose diseases more efficiently.
Researchers discovered that aggressive breast cancer prompts nearby immune cells to build 'molecular bridges' between themselves, suppressing the immune response. An antibody treatment that blocks these bridges was shown to restore the immune system's ability to attack with force, inhibiting tumor growth in a mouse model.
Scientists uncover hidden quantum behaviors within classical light, revealing two contrasting behaviors: classical and quantum coherence. This discovery could lead to more robust quantum technologies, mitigating decoherence and accessing quantum properties.
The study reveals that twisting the filament at micro and nanoscale produces light waves with elliptical polarization, offering a new avenue for robotic vision systems. Brightness is up to 100 times brighter than other approaches, but includes a broad spectrum of wavelengths and twists.
A new gene editing tool called SPLICER has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease. The application shows improved efficiency over current standard gene editing technology and potential for application in other diseases.
Counterfeit spirits cost the EU €3 billion annually, with 25-40% of consumption in some areas. Experts advise monitoring 4 P's: product, price, package, and place of purchase to avoid contaminated alcohol-related deaths. A database is being built to test and compare alcoholic spirits using chemical fingerprints.
Between 2020 and 2023, buprenorphine dispensing to adolescents increased, while prescribing declined among young adults. These changes are attributed to improved outreach, telehealth prescriptions, and elimination of waiver requirements.
Scientists discovered that indoor air quality remained compromised weeks after the devastating Marshall Fire, releasing gases harmful to human health. Researchers tested methods to mitigate smells and VOC concentrations indoors, finding that opening windows and running air cleaners decreased gas levels by over 50%.