Researchers found that autologous fat grafting can reverse dermal adipose tissue dysfunction by inducing autophagy and mitophagy. This process improves skin architecture and reduces fibrosis in conditions like scleroderma.
Researchers from the University of Tokyo used ocean model simulations to investigate the long-term tritium distribution after Fukushima's treated water release. The study found that tritium concentrations remain very low, with no significant impact on ocean levels.
A recent study suggests that Mars' surface features were shaped by short periods of liquid water, followed by 100-million-year-long periods of desert. The research, led by University of Chicago scientist Edwin Kite, proposes a new explanation for why Mars became a barren desert planet.
Researchers argue that boosting entrepreneurship is counterproductive to Africa's economic development due to a lack of large firms. The study suggests that focusing on building large firms and adopting strategies from East Asia's successful growth models could be more effective.
A new study by the University of Exeter found that group work and discussion help students build confidence when using maths in science lessons. Researchers identified four different ways students approach maths problems, including those with science-dominant thinking and others who focus on equations.
Scientists have introduced an innovative approach to trap enzymes within nanoscale protein compartments, simplifying their use and extending their functional lifespan. This reduces costs and enhances reusability, offering a more sustainable pathway for PET recycling.
MIT researchers have designed cheap, disposable electrochemical sensors that can detect multiple diseases using DNA-coated electrodes. The sensors were stabilized with a polymer coating, allowing them to be stored for up to two months, enabling potential use in low-resource regions and at home.
Researchers at Helmholtz Munich developed an AI model called Centaur that can simulate human behavior with remarkable accuracy. It was trained on over ten million decisions from psychological experiments and makes decisions that closely resemble those of real people. The model opens new avenues for understanding human cognition and imp...
Researchers develop smart planning systems to predict weld bead geometry and optimize deposition paths, reducing thermal stresses and defect rates. Innovations in real-time monitoring and auxiliary strategies improve material integrity and mechanical properties.
A new cytokine delivery platform reprograms the tumor microenvironment to enhance CAR-T cell function in preclinical brain cancer models. The strategy leads to a broader immune response that inhibits tumor growth and extends host survival, even in mice with only a fraction of cells expressing the CAR-targeted antigen.
Researchers at Ruhr-University Bochum have discovered that hepatitis E viruses can infect kidney cells, leading to a potentially insurmountable challenge in treating the infection. The study found that infected kidney cells responded poorly to antiviral medication, suggesting the virus has evolved to evade treatment.
A comprehensive study protocol has been developed to investigate pregnancy-related stroke risk factors and long-term implications for mothers and their children. The nationwide multicenter study aims to identify key risk factors associated with ASPP and assess its impact on offspring.
Researchers at The University of Osaka develop AI-powered method to analyze urban vegetation color, structure, and seasonal changes using street view imagery. This allows city planners to enhance the 'feel-good' factor of urban green spaces throughout the year.
A Rutgers Health study has discovered a way to precisely identify and target trauma sites in the body within minutes of injury. The 'traumome' is a unique protein signature that can be detected after an injury, enabling real-time diagnostics and site-specific treatments.
Researchers have discovered a protein called BACE1 that helps lung cancer spread to the brain, where treatment options are currently limited. The study suggests that existing Alzheimer's drugs could be repurposed to prevent or slow the spread of lung cancer to the brain.
Researchers propose using chemical sensors to diagnose bacterial infections by detecting volatile organic compounds in bodily fluids, providing a rapid and affordable diagnostic test. The technology has the potential to improve treatment plans and combat antibiotic resistance.
Researchers have developed a novel biosensing platform combining CRISPR-Cas10 with graphene field-effect transistors (GFETs) for amplification-free RNA and microRNA detection. The approach achieves detection limits at the attomolar level, making it suitable for health monitoring and disease diagnosis.
Researchers pioneer a new AI method to uncover cognitive strategies in decision-making, revealing suboptimal behavioral patterns. The study uses small neural networks to predict animal choices with accuracy comparable to larger neural networks.
Scientists developed mouse models that survive premature death, enabling pre-clinical testing of alternating hemiplegia of childhood (AHC), a devastating neurological disorder. The research reveals how different mutations can lead to distinct outcomes in AHC and sets the stage for developing gene editing therapies.
A study published in PLOS One finds that early childhood education policies worldwide favor competition, individualism, and talent over cooperation, solidarity, and luck. Only four countries acknowledge uncontrollable factors like health and climate disasters as contributors to success.
A recent study by Columbia University researchers found that early education has a significant impact on adult cognition, especially for individuals from low-income backgrounds. The study compared adult siblings in Indonesia and isolated education's effects on quantitative and abstract reasoning, separate from family background factors.
Researchers have identified a single genetic difference in Fas Ligand, an immune protein, that makes it vulnerable to being disabled by plasmin, a tumor-associated enzyme. This vulnerability seems unique to humans and may contribute to the effectiveness of certain cancer treatments.
A new nanocomposite hydrogel system has been developed to address the dual challenges of inflammation and cartilage damage in osteoarthritis. The hydrogel promotes cartilage repair through synergistic immune regulation and chondrocyte differentiation, offering a novel therapeutic strategy for OA.
Researchers developed AI-created thermal meta-emitters that can selectively emit heat at various levels, making them ideal for energy efficiency. These materials were found to be up to 20 degrees Celsius cooler than commercial paints in a four-hour exposure to direct sunlight.
A preclinical study has identified a signaling pathway involving GAS6 and AXL proteins that enables rapid healing of oral mucosa wounds. The findings suggest that manipulating this pathway could help reduce skin scars.
A new global report highlights concerns about the state of democracy, with major democracies like the UK and US experiencing declines in electoral quality. Iceland tops the leader board for democracy, but experts warn that countries like Mexico, Indonesia and Russia are struggling with election integrity.
Northern Arizona University is taking stock of its 5,000-6,000 trees to advance sustainability and carbon sequestration. The project will provide hands-on research opportunities for students and shed light on the trees' ability to mitigate climate change.
A study by Universitat Oberta de Catalunya found that theatre-based interventions improve the emotional well-being of patients with Parkinson's, reducing depression and anxiety. Group activities foster emotional connections, increase empathy, and provide social support.
A new study found that customers overwhelmingly reject gratuity requests made prior to service, leading to negative attitudes towards tipping. However, the researchers discovered that making customer-service efforts visible can offset these reactions and improve decision satisfaction.
A new approach suggests using quasi-experimental methods to estimate project impacts, reducing overestimated emissions reductions and increasing the effectiveness of carbon offsets. This could involve mechanisms like risk sharing along the value chain to overcome implementation hurdles.
A new perspective on Peto's paradox highlights the importance of studying species that resist cancer naturally, which may offer insights into understanding cancer and aging. Understanding how cells interact with their environment could provide deeper insight into how cancer develops or is prevented.
The article discusses the use of solution-processed 2D materials to fabricate memristors, offering a scalable alternative to traditional methods. Recent breakthroughs have overcome manufacturing limitations, producing larger and less-damaged nanosheets with improved device performance.
A new study reveals how the body preserves long-term immune memory in the lungs after viral infection by relocating immune cells to nearby lymph nodes. Researchers identified the chemokine receptor CCR5 as the key molecule guiding this movement.
The study identifies the need for more widely adopted non-animal methods to identify endocrine-disrupting substances in the EU. The researchers advocate a balanced approach that includes both developing and validating alternative methods and refining animal testing.
Researchers sequenced the oldest Egyptian genome from a 4,500-4,800 year-old individual, tracing ancestry to North Africa and the Fertile Crescent. The study provides genetic evidence of population mixing in ancient Egypt during this period.
A community-based pneumococcal vaccination support program in Sera Town, Japan, reduced pneumonia-related mortality by 25% among the elderly. The program reversed a previously increasing trend in pneumonia mortality rate in the community.
Financial stressors significantly affect relationship happiness, but collaborating on finances can change this. Military couples who budget and make financial decisions together report better interactions with their partners and a stronger relationship.
A five-week creative play programme has significantly improved new parents' and carers' mental health by reducing postnatal depression symptoms. The programme, Let's Play, encourages social connections between parents and boosts confidence.
A study of over 500 women aged 35-55 found that chronologic and reproductive age both significantly impact a woman's level of anger and ability to manage it. As women age, their anger traits decrease, suggesting better emotion regulation may occur during midlife.
The study provides a comprehensive framework for understanding instrument separation during root canal therapy, emphasizing advanced retrieval techniques and preventive measures. It recommends step-by-step protocols to mitigate complications and preserves natural teeth. The guidelines highlight innovations like ultrasonic methods and m...
A novel model reveals that local Ang II regulation plays a crucial role in maintaining kidney function balance. The study found that damaged kidneys compensate for the loss of function by increasing blood pressure and reducing glomerular atrophy.
The science community must rethink how it engages society in scientific discovery, controversy, and policy. A new 'collaboration model' is needed to create a level playing field for input, embrace uncertainty, and invite more public conversations.
Researchers at Fujita Health University discovered benzaldehyde's mechanism to halt therapy-resistant pancreatic cancer growth and spread. Benzaldehyde prevents key interactions that enable cancer cells' survival and treatment resistance.
A new study by Colorado State University outlines a path to creating advanced, recyclable plastics using natural poly(3-hydroxybutyrate) (P3HB). The breakthrough method involves stereodivergent catalysis, which enables the production of enantiopure PHAs with improved properties for various applications.
A team of researchers proposes a novel adaptive platform trial fund to accelerate ALS drug development. The study outlines a financing model that merges efficiencies with an innovative royalty-based investment structure, drawing on data from the HEALEY ALS Platform Trial. This new approach could transform how diseases like ALS are addr...
Researchers have developed a sustainable desalination method using a sponge-like material with long microscopic air pockets that can turn saltwater into freshwater in natural sunlight. The system successfully produced potable water in a proof-of-concept test, providing a scalable and energy-free solution for producing clean water.
Researchers at Tohoku University's AIMR have developed data-driven strategies to advance methane pyrolysis catalysts using artificial intelligence and machine learning. These approaches enable the identification of key physicochemical properties influencing catalyst performance, suggesting novel compositions for experimental validation.
A new study suggests that sustained US military spending reductions could lead to substantial decreases in energy consumption, with potential annual savings comparable to those of Slovenia or Delaware. The analysis found that decreased spending primarily affects energy consumption from facilities, vehicles, and equipment, and jet fuel.
Researchers developed a technique to measure brain tumors' mechanical force, distinguishing between tumors that push against the brain or invade surrounding tissue. This measurement can help clinicians inform patient strategies to alleviate symptoms and predict outcomes of chemotherapy and immunotherapy.
A new economic analysis found that developing countries get more nutrition for every dollar spent on imported seafood compared to wealthier nations. They receive more protein, fatty acids, iron, and vitamin B12 due to lower prices for frozen fish.
The Hebrew University of Jerusalem is part of a €9.3 million, 36-month Horizon Europe project to develop trustworthy GenAI systems. The consortium aims to integrate neural and symbolic methods for human-centric design in complex systems.
A pilot intervention project involving playful sensory-motor activities improved reading speed and eye movements in children with dyslexia. The study found promising results in improving eye movements and reading speed in eleven children aged 10-12 who underwent a two-month protocol of cognitive engagement, reducing reading time and in...
Researchers at WVU have designed a fuel cell that can switch between storing and generating electricity, making it suitable for balancing an overwhelmed US electrical grid. The new design, called conformally coated scaffold, stays stable even at high temperatures and humidity levels.
A new hydrogel-based platform has been developed to preserve live patient-derived tumor tissues in the lab, enabling more accurate testing of cancer treatments. The approach, which uses customizable bioengineered hydrogels, has been shown to retain key features of the original tumor environment.
The institutions aim to strengthen global cancer research through scientific cooperation and foster the next generation of cancer researchers. They will establish a multimillion-dollar endowment to support research, symposia, and trainee exchange between both institutions.
A new study highlights major hurdles for multinational clinical trials in Europe, including differences in timelines and processing times between countries. Researchers found that the UK made significant gains in efficiency during the pandemic, while non-UK countries lagged behind.
Scientists at the University of Helsinki discovered that gas leakage through a wound triggers plant regeneration, using ethylene and oxygen as signals. This finding has implications for improving crop resilience, reducing post-harvest food waste, and enhancing agricultural sustainability.
In a groundbreaking study, researchers discovered that strong magnetic fields can reverse the overall direction of angular momentum in magnetovortical matter. This finding challenges established theories and highlights the previously underestimated role of orbital motion in certain regimes.
A KAIST research team discovered a method to enhance glioblastoma immunotherapy by restoring microbial diversity in the gut. Tryptophan supplementation activated beneficial strains of bacteria, increasing CD8 T cell infiltration into tumor tissues and improving survival rates.
The LAFERIA Project focuses on identifying key factors for reintroducing landscape features, evaluating their benefits and challenges, and developing strategies to overcome them. The project will employ a participatory engagement framework to work with stakeholders across seven European countries.