Researchers found that changes in gut bacteria after a stroke lead to an increase in harmful substances and a decrease in beneficial ones, potentially causing inflammation. Restoring these beneficial substances from gut bacteria could help reduce inflammation after a stroke.
Novel strategies utilizing Bound States in the Continuum (BIC) significantly improved Q-factor values, with records of up to 92,091. A breakthrough electrically pumped BIC laser was successfully demonstrated with a Q-factor of 11,776.
A recent study introduces a groundbreaking method for early crop identification, leveraging the Bayesian Probability Update Model (BPUM). The method combines historical planting data with real-time remote sensing observations, enabling accurate predictions of crop distribution 1-2 months ahead.
Patients prioritize continuity of care over rapid access to clinicians, with over half preferring their own primary care physician. The study's findings suggest that health systems may need to balance convenience with patient preferences for trust and continuity in primary care.
A recent study from the Indian Institute of Science found that cloud band strength plays a key role in its movement and density of rains during Indian wet spells. The researchers discovered that only strong equatorial cloud bands drive northward propagation, increasing moisture and triggering stronger winds.
Researchers studying White-necked Jacobins found a unique caterpillar-like appearance on a newly hatched hummingbird chick, which may be an adaptation to avoid predators. The chick's fluffy down feathers and camouflaged nest suggest potential mimicry or camouflage strategies.
Preet Chaudhary and Michael Selsted, USC innovators, recognized by the National Academy of Inventors for their work on harnessing the power of the immune system. Their research aims to develop new treatments for diseases such as cancer, rheumatoid arthritis, and sepsis.
Long-term inhaled corticosteroid use increases risk of type 2 diabetes, cataracts, pneumonia, osteoporosis, and fractures in individuals with chronic obstructive pulmonary disease (COPD). Long-term ICS users are nearly three times as likely to develop recurrent cases of pneumonia and fractures.
A University at Buffalo study found that pregnant women who ate chili once per month had a 3.5% risk of developing gestational diabetes, compared to 7.4% for those who never ate chili. The researchers attribute the benefits to capsaicin and phenolic compounds in chili.
A research group successfully synthesized lignan glycoside in yeast Saccharomyces cerevisiae using a synthetic yeast consortium. The approach reduced side reactions and improved metabolic flux toward the target product.
A multicenter study found targeted next-generation sequencing to significantly outperform traditional culture methods in detecting urinary tract infections, including polymicrobial cases. The method's detection time was notably shorter, with high concordance rates for both culture-positive and negative samples.
A study confirms plasma p-tau217 as a blood-based biomarker for early Alzheimer's detection in Asian populations. Higher levels correlate with faster cognitive decline, suggesting its potential role as both diagnostic and predictor tool.
A new study reveals that expectant and new fathers, particularly Black American fathers, express a significant need for more resources and support to better assist mothers during pregnancy and childbirth. The research highlights a gap in tailored information and resources for fathers within healthcare and social service systems.
The UH Portage Medical Center's heart lab and prevention programs have shown a significant reduction in ischemic heart disease mortality, especially among older adults. The study found declines of 36% in the 65-74 age group and 28% in those over 85.
A new hepatitis B vaccine, Heplisav-B, was compared to standard vaccines in a study of previously vaccinated individuals. The results showed that Heplisav-B was more effective at boosting immunity, with 99.4% achieving protective levels compared to 92.7% for standard vaccines.
Researchers have identified a potential new gene target, FLT1, that could be edited to treat sickle cell disease by increasing fetal hemoglobin levels. The study found 14 new genetic markers associated with fetal hemoglobin production, which could help preserve the type of hemoglobin present at birth.
Researchers found that placing naloxone kits in transit stations could improve availability and save more lives. By optimizing distribution strategies using mathematical models, the team discovered that just 60 kits at 650 locations could cover over half of opioid poisonings in Vancouver.
The review elucidates fundamental principles of tandem catalysis, presenting design strategies for multifunctional catalysts or cascade reactors. It analyzes cutting-edge advancements in multiscale tandem methodologies, including compositional engineering and hydrodynamic modulation.
Researchers at NYU Abu Dhabi have developed an innovative sensing system that restores tactile feedback in minimally invasive surgery. The 'off-the-jaw' system integrates force and angle sensors into laparoscopic tools, providing real-time measurements of grasping forces and tissue stiffness.
A study published in the British Journal of General Practice found a significant link between chest x-ray referrals and earlier lung cancer diagnosis and better survival rates. Patients attending practices with high chest x-ray usage were more likely to be diagnosed at an earlier stage, leading to improved survival rates.
Ferroptosis impairs immune function by inducing cell death in key immune cells such as macrophages, neutrophils, and T cells. It also affects B cells and NK cells, leading to immunosuppression in diseases like cancer and cardiovascular disease.
NJIT's forensics program showcased new research and innovations, including a virtual reality crime scene reconstruction tool, CSIxR, which simulates scenarios to train investigators. The app aims to augment hands-on training, making forensic education more accessible and impactful.
A recent study reveals vermicomposted olive waste influences volatile compounds emitted by olive trees, affecting attraction of beneficial lacewings. The research highlights the importance of belowground ecology in plant defense mechanisms and its potential to enhance biological control strategies.
A new study from City St George's University of London found that lower-income countries focus on material concerns like economic issues, while richer nations debate personal freedoms and identity-related issues. The research analyzed 40 years of global data to explore how modernization influences ideological divides.
The study found that the 'About Me' Care Card helps clinicians identify patient concerns earlier, creating personalized care conversations. However, some patients with advanced cognitive challenges required assistance, highlighting the need for further development and refinement of the tool.
A new brief warns that assistive AI may worsen challenges related to error prevention and physician burnout. The researchers predict that medical liability will depend on who is considered at fault when the technology fails, subjecting physicians to unrealistic expectations.
A population-based surveillance study found that Black infants and children consistently have double the risk for death compared to Whites. The study analyzed data from 1950 to 2019 and estimated excess mortality burden on Black Americans compared to White Americans.
A new study from the University of Colorado Anschutz Medical Campus identified significant mitochondrial dysfunction in lymphoblast cell lines from children with Dravet syndrome, a severe form of epilepsy. The findings suggest that mitochondrial defects play a role in the metabolic dysfunction observed in Dravet syndrome.
The COVID-19 pandemic significantly reduced ambulatory antibiotic use in France, with most antibiotics showing a notable decrease. Antibiotic use remained lower than expected levels for at least 12 months following the first lockdown.
Participating in insect-related citizen science projects boosts students' intentions to change their personal behavior and encourage others to protect nature. Teachers also report increased interest in incorporating insect-related topics into their teaching, leading to a positive association with student pro-environmental behavior change.
Researchers have developed an extension of process calculus to model epistemic interactions between agents with epistemic states, enabling the capture of asynchrony. The e-calculus can be used to characterize synchronous and asynchronous communications between agents, with potential applications in intelligent agent systems.
Researchers from Syracuse University found potential benefits of transcranial direct current stimulation (tDCS) on attention and fatigue in post-stroke patients, but results were mixed. Participants who received real tDCS showed decreased fatigue, while actual treatment did not improve attention tests.
Materials Research Society elects Miaofang Chi and Rigoberto “Gobet” Advincula as Class of 2025 Fellows for their outstanding work on novel electron microscopy methods, advanced polymers, and nanostructured materials. New Fellows will be recognized at the MRS spring meeting in April 2025.
A study found that only 75.3% of chlamydia cases and 69.6% of gonorrhea cases were treated within 30 days of diagnosis, with disparities observed among certain patient groups.
A family-based approach to lifestyle interventions significantly improves weight management and cardiovascular health among individuals with a family history of premature coronary heart disease. The study found that participants who received structured lifestyle counseling experienced notable reductions in weight, BMI, and waist circum...
A megastudy involving over 140,000 teachers and 3 million elementary students found that behaviorally informed email messages improved students' math progress by 1.89% compared to standard email reminders. Personalized nudges referencing students' progress updates were more effective than nonpersonalized ones.
Researchers developed a new IVF method that uses glycans to bind and store sperm, increasing fertilization rates and prolonging sperm viability. The method aims to improve IVF success for both animals and humans, particularly in cases where timing mismatches between egg maturity and sperm viability are critical.
Researchers found robust, virus-fighting T cells in lung tissue that correlate with reduced viral load, inflammation, and improved respiratory function. These cells maintain a polyfunctional memory phenotype after viral clearance, highlighting their role in controlling COVID-19.
Patients with hormone receptor-positive and HER2-negative breast cancers face a higher risk of death from the cancer if they wait more than 42 days after diagnosis to have surgery. Delayed surgery increases the patient's risk exponentially, with risks of death increasing by 21%, 79%, and 183% at 60, 90, and 120 days, respectively.
A family-based approach to lifestyle interventions significantly improved weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease. The study found that participants experienced an average reduction of 2.61 kg in weight, 1.06 kg/m² in BMI, and 4.17 cm in waist cir...
A qualitative study identified key teamwork strategies that high-performing clinics use to promote regular follow-up visits for adults with chronic conditions. These strategies include close working relationships between staff members, structured follow-up systems, and proactive patient outreach.
Researchers propose darkening cities to improve biodiversity, human health, and reduce energy waste by embracing nocturnal living. Professor Nick Dunn's 'Dark Futures: When the Lights Go Down' presents a vision for an alternative future that reconnects humans with nature's rhythms.
A team of researchers from Bonn and Tübingen investigated the brain's ability to retain a sequence of events in memory using implanted electrodes. They found that the traditional theory was contradicted by their data, but an alternative mechanism emerged through AI simulations.
A study published by Tohoku University reveals that epileptic seizures can significantly reduce ATP levels in neurons, while increasing pyruvate levels in astrocytes. This finding challenges the traditional view of brain energy dynamics and suggests a more complex interplay between neuronal activity and metabolic processes.
Researchers have detected unprecedentedly large organic molecules on Mars, containing up to 12 consecutive carbon atoms. These findings provide valuable insights into the planet's potential for life and pave the way for future interplanetary science missions.
The device enables precise control over terahertz wave polarization, revolutionizing applications such as data transmission, imaging, and sensing. This innovation promises to transform fields like wireless communication and biomedical imaging.
A team of researchers used light stimuli to shape starfish oocytes, creating a model that explains the mechanisms behind dynamic cell shape changes. The study has wide-ranging implications for synthetic biology and cell-based technologies.
A recent study reveals how Epstein-Barr virus (EBV) aggravates ulcerative colitis (UC) through macrophage pyroptosis, a form of inflammatory cell death. EBV infection accelerates glycolysis, leading to increased inflammation and intestinal damage in UC patients.
Researchers investigated the impact of plasma storage conditions on endogenous miRNA stability. They found that degradation rates can be affected by miRNA structure and packaging, as well as extraction methods.
Prof. Yinon Ben-Neriah has made significant contributions to cancer research, identifying key processes by which inflammation facilitates cancer development. His work has led to the creation of novel therapeutic strategies and anti-cancer drugs widely used worldwide.
A new study finds that global heating could exceed previous estimates, with even low emission scenarios leading to higher temperatures. The Paris Agreement's goal of limiting warming to 2°C may only be achievable under very low emissions and lower-than-estimated climate sensitivity.
A new real-time surface PM10 retrieval framework uses interpretable automated machine learning to provide accurate data across China. The framework demonstrates robust generalization and stability, outperforming previous studies in cross-validation and rolling iterative validation experiments.
A new study found that children with ADHD have a notable increase in functional connectivity while playing a virtual reality game, providing new insight into the condition. The results suggest that psychological testing for ADHD should be conducted in situations where symptoms are triggered.
Mass General Brigham researchers developed an olfactory test, where participants sniff odor labels on a card, to assess cognitive impairment. The test showed promise as a tool for identifying risk of cognitive decline and was found to be successful at home.
A new study by Brown University researchers found that avoidable mortality increased across all US states from 2009 to 2021, while declining in many peer nations. The team's findings suggest deep-seated issues in the American healthcare system and public policy may be contributing to worsening health outcomes.
A University of Bristol-led study suggests electric scooter schemes reduce bicycle collisions by around 20% in the UK. The research found that even after COVID-19 restrictions lifted, e-scooter scheme areas saw a significant decrease in serious and fatal bicycle collisions.
The IP4OS project aims to integrate Intellectual Property management with Open Science principles, ensuring research outputs are both protected and accessible. The 24-month project will create practical strategies for knowledge valorisation and empower researchers to navigate the complexities of knowledge sharing.
A study led by the German Centre for Integrative Biodiversity Research found that tree diversity significantly enhances forest temperature buffering, particularly during heat peaks. Species-rich forests showed a greater cooling effect, up to 4.4°C stronger than single-species forests.
Researchers directly observed DNA formation into rod-shaped chromosomes during cell division, revealing the role of condensin complexes and their looping process in compaction. This discovery provides insights into the molecular mechanism of chromosome segregation.
Researchers have identified several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of tuberculosis in cattle. The study found that genetic variation affecting the initial proinflammatory immune response contributes to bTB susceptibility.