The Center for Open Science has launched the Predicting Replicability Challenge to accelerate the development of methods for evaluating research credibility. Teams will compete to develop algorithmic approaches that can accurately predict the likelihood of research claims being successfully replicated, with cash prizes ranging from $3,...
Researchers analyzed chloroplast genomes of cacao trees from northern Peru to determine the species' age and diversity. The study found that the current known diversity diversified during the Pliocene or Miocene epochs, approximately 7.5 million years ago.
Researchers at ETH Zurich discovered that pupil dynamics is related to specific patterns of brain activity and arousal levels, contradicting previous assumptions about low arousal during sleep. The study uses pupil measurements to monitor brain activity in humans for the first time.
A new study highlights the need for more diversity in genomics research, as a commonly found gene variant was mistakenly linked to heart disease in people from Oceanian communities. The researchers found that the variant is actually common among healthy individuals from these regions.
Scientists at Oak Ridge National Laboratory developed a new way to measure high-speed fluctuations in magnetic materials. This discovery could lead to advancements in technologies such as computing and data storage.
Researchers discovered a collection of 27 fossilized bones with shaped into hand tools 1.5 million years ago by early human ancestors. This find suggests that hominins had an advanced understanding of toolmaking, adapting techniques to different materials, indicating greater cognitive skills.
Jerome E. Morris has been voted president-elect of the American Educational Research Association (AERA), succeeding Maisha T. Winn. Morris will leverage his research on race, social class, and educational opportunity to inform his presidency.
A new study by Weill Cornell Medicine researchers has identified a potential biomarker for joint inflammation in Crohn's disease patients, the bacterium Mediterraneibacter gnavus. The study found that M. gnavus is associated with increased immune cell responses and disease activity scores in patients with joint inflammation.
Breast and colorectal cancer screening rates have recovered from pandemic-related declines, surpassing pre-pandemic estimates. Cervical cancer screening rates remain below pre-pandemic levels, indicating a persistent trend of declining early-stage diagnoses.
Female Guinea baboons court males with special foraging skills more intensively due to the short-term benefits they provide. This suggests that females prioritize immediate rewards over long-term evaluations of male competence.
A nursing study pairs teens and older adults with smartwatches to test monitoring health in under-resourced communities. The results show that 91% of older adults engaged with the smartwatch prompts, highlighting the importance of social engagement for brain health.
A new study found that individuals with anxiety and depression symptoms exhibit lower confidence in their judgment, while those with compulsivity show higher confidence. This link sheds light on the intricate relationship between cognition and mental health manifestations.
Children's Hospital of Philadelphia researchers have discovered a key process where malarial parasites take up human blood cell enzymes, which could provide a new approach for antimalarial treatment. The findings suggest that a human enzyme, acylpeptide hydrolase (APEH), is the major activating enzyme of multiple antimalarial prodrugs.
A POSTECH research team developed a photoacoustic computed tomography (PACT) system that non-invasively monitors cerebrovascular changes in small animals with early stages of an ischemic stroke. The technology also measures oxygen saturation in blood vessels, allowing precise tracking of vascular recovery after stroke.
The Mount Sinai Hospital has become the first in the US to perform a deep brain stimulation (DBS) implantation procedure as part of a clinical trial investigating its effectiveness for treatment-resistant depression. The study aims to gather evidence on the impact of DBS systems developed by healthcare company Abbott.
Researchers from the University of Göttingen have discovered a molecular 'spring' that triggers the opening of ion channels in sensory hair cells of the ear. The findings provide new insights into how hearing begins at the molecular level and shed light on the function of ion channels.
A new study proposes a theoretical framework for AI-based wearable blood pressure sensors, paving the way for non-invasive and continuous cardiovascular monitoring. The review highlights clinical aspects of implementation, real-time data transmission, and signal quality degradation, and presents strategies to address technical barriers.
Researchers at Stanford University have discovered a method to use two antibodies to effectively combat the constantly evolving virus, which could lead to longer-lasting treatments for COVID-19. The antibodies were shown to be effective against all SARS-CoV-2 variants in laboratory testing.
The American Heart Association's webinar will explore the benefits of charitable gift annuities and qualified charitable distributions, helping donors maximize their giving potential while ensuring a reliable income stream. Participants will also gain insights into how to create a lasting legacy for causes close to their heart.
New research reveals lyrebirds' 'farming' behavior creates ideal conditions for invertebrates, boosting size and diversity. The birds rake forest floors to alter microhabitats, shape plant germination patterns, and even lower bushfire intensity.
A Rutgers University study found that people are exposed to over 100 chemicals through personal care products daily, with varying health concerns across product categories. Researchers recommend practical steps for consumers to reduce exposure, such as using fewer products and choosing safer alternatives.
A POSTECH research team has developed a new catalyst using aluminum, improving the performance of hydrogen production in alkaline water electrolysis by approximately 50%. The aluminum catalyst maintained high current density and excellent stability, making it suitable for large-scale hydrogen production.
Researchers found caribou migration areas decreasing significantly over 35 years, with seasonal migrations shrinking in duration and extent. Habitat loss and human-caused disturbances are correlated with these changes, posing a threat to the species' survival.
Researchers developed gene-edited lettuce with significantly higher levels of β-carotene, zeaxanthin, and ascorbic acid without compromising plant growth. This breakthrough highlights the potential of gene editing to combat micronutrient deficiencies and improve dietary quality.
A new TB vaccine candidate has shown complete protection and a superior immune response in nonhuman primates compared to the existing BCG vaccine. The delta sigH vaccine resulted in a more balanced and effective elimination of the bacteria, with lower levels of inflammation and a different type of interferon triggered.
Researchers have identified powerful antibodies capable of neutralizing a wide range of norovirus strains, paving the way for designing a broadly effective norovirus vaccine. The discovery brings us closer to a vaccine that could provide lasting protection and prevent devastating effects of norovirus outbreaks.
Researchers have directly observed water molecules flipping before splitting, which explains why the process requires more energy than expected. This finding could lead to new insights into increasing the efficiency of water splitting, a crucial step in generating clean hydrogen fuel and producing breathable oxygen.
The Whole Health Consortium at Virginia Tech has funded several research projects, including one that uses geospatial analysis to improve healthcare access for veterans. Another project aims to develop a 'just-in-time' intervention for chronic pain and opioid use disorder in Appalachia.
Scientists have created a shelf-stable formulation of Sporosarcina pasteurii bacteria that can produce biocement when exposed to calcium chloride and urea. This breakthrough could enable the use of powder packets to quickly make tiles, repair oil wells, or strengthen ground for makeshift roads or camps.
Researchers at Johns Hopkins University have discovered genes that control fruit size in tomatoes and eggplants, opening up opportunities for new varieties and improved agriculture. The study could lead to the development of larger, more nutritious fruits, and has significant potential for global food security.
A NIH-funded research team has engineered a medication that targets the body's cannabinoid receptor type 1 (CB1), which shows promise in treating acute and chronic pain. The new drug, VIP36, is more 'peripherally restricted' compared to previous drugs, reducing unwanted side effects.
A new AI prediction model, UNAFIED, uses machine learning to predict whether a patient has or might develop detectable AFib within two years. The non-invasive approach provides a practical option for proactive screening of patients at elevated risk for AFib.
Researchers at the University of Missouri have identified a small molecule drug that targets a specific serotonin receptor, showing promise as a treatment for sarcopenia. The study suggests that this neurotherapeutic can improve muscle strength by activating motor neurons to fire more effectively.
A Cornell University-led collaboration has designed a new method for creating metals and alloys that can resist extreme impacts and stresses. The research introduces nanometer-scale speed bumps that suppress embrittlement in metallic materials.
Andrew Barto and Richard Sutton's pioneering work in reinforcement learning has been recognized with the 2024 ACM A.M.Turing Award. Their algorithmic foundations have led to significant advances in AI, including deep reinforcement learning.
Scientists at CSHL and global collaborators have sequenced complete genomes for the Solanum genus, including tomatoes, potatoes, and eggplants. The study reveals the importance of understanding paralog genes in predicting genome editing outcomes.
Researchers found that aspirin prevents cancers from spreading by decreasing a clotting factor called thromboxane A2 and releasing T cells from suppression. This discovery could lead to the development of targeted treatments to prevent cancer metastasis, making aspirin potentially less expensive than antibody-based therapies.
A Japanese study found that smoking during pregnancy increases the risk of placental abruption by 2.8%, while second-hand smoke exposure contributes an additional 3.0% risk. The study highlights the importance of preventing all smoke exposure in public spaces and homes to safeguard maternal and fetal health.
The 3rd International Conference on UltrafastX (UltrafastX 2025) will take place in Xiamen from October 23 to 26, 2025. The conference will cover topics such as ultrafast lasers, imaging, and terahertz science and technology.
Researchers create microfluidic device to sort tumor cells based on adhesive strength, revealing potential method to predict aggressive cancer behavior. The study's findings offer a promising approach for personalizing treatment plans and identifying high-risk patients.
Researchers at USC Stem Cell discovered a gene called KCTD20 that suppresses glutamate toxicity, leading to enhanced tau protein clearance. This approach offers a promising therapeutic strategy for patients with tau-related neurodegenerative diseases, including Alzheimer's disease.
A new study from the University of Surrey suggests that hotels can significantly reduce their environmental impact by prioritizing vegetarian and plant-based options on restaurant menus. By strategically framing these dishes as first choices, hotels can guide guests toward more sustainable food choices.
Core-shell nanoparticles offer effective drug encapsulation, shielding from degradation, and controlled release. This innovation enables targeted drug delivery, improving treatment outcomes and reducing side effects. The versatility of these nanoparticles allows for tailored materials to suit different therapeutic needs.
A recent study published in Nature Communications provides detailed data on the far-field spatial footprint of mining-induced plume dispersion and redeposition beyond the mining area. The research found that sediment concentrations were up to 10,000 times higher near the mining site and returned to normal levels after 14 hours.
A large-scale study found that police officers with more active amygdalae before training were more likely to experience PTSD symptoms after traumatic events. The study suggests that understanding individual differences in amygdala activity can help make people more resilient to trauma.
A Rutgers Health study reveals that people with disabilities face significant barriers to accessing quality healthcare, including negative interactions with providers. The findings underscore the need for disability-competent and affirming care, particularly in light of recent policy changes impacting disabled patients.
A new US study published in JAMA found that vaping does not help smokers quit and may actually hinder the process. The study analyzed data from over 6,000 US smokers and found no correlation between vaping and increased smoking cessation rates.
Researchers found differences in genes and brain wiring between forest and desert flies, explaining how climate change impacts insects. Forest flies show increased avoidance of heat, while desert flies are attracted to warmer temperatures.
A new study by MIT confirms the Antarctic ozone layer is healing, with high statistical confidence that reductions in CFCs are the primary cause. The research uses fingerprinting to isolate the anthropogenic signal and rule out natural variability.
A new study found that sports gambling frequency is associated with the trajectory of alcohol-related problems over time. Screening and treatment interventions are recommended for this high-risk group to prevent further problems.
Researchers found a single young adult Paranthropus robustus fossil with evidence of habitual upright walking, weighing only about a meter tall and 27 kg at death. The species' small size made it vulnerable to predators like sabertooth cats and giant hyenas.
Researchers at Carnegie Mellon University have developed a new, minimally invasive method called DeepFocus for treating depression and other neural conditions using transnasal electrical stimulation. This technique offers more accurate and efficient targeting of deep brain structures with lower risk.
Researchers used terahertz spectroscopy to study agave plants' ability to retain water in dry environments. They found that agaves store water in a specialized leaf structure and fructans act like molecular sponges to retain moisture. This discovery could lead to better farming practices and drought-resistant crops
Scientists have created nanocone arrays that exhibit enhanced amplified spontaneous emission due to strong coupling, enabling high Q/V resonant modes and accelerating micro-nano laser development. The research also demonstrates the manipulation of spatial distribution, mode selection, beam directionality, and polarization control.
The Aligning Science Across Parkinson’s (ASAP) initiative offers funding of up to $6M for research community members to develop sustainable tools for Parkinson’s disease research. The funding supports the development of preclinical models, detection reagents, and modulation agents to accelerate therapeutic research.
Recent research has shown that microRNAs (miRNAs) are involved in myocardial cell proliferation, differentiation, and metastasis, promoting the progression of diabetic cardiomyopathy. Targeted regulation of immune cells through miRNA-mediated therapy may provide new avenues for treating this debilitating condition.
Researchers at TUM have developed a novel method to purify proteins using short-wave UV light, eliminating the need for chemical reagents. The 'Azo-tag' system changes shape under light exposure, allowing for targeted purification of proteins in a more efficient and gentler manner.
A large-scale Korea University study investigates the link between early menopause and type 2 diabetes risk among postmenopausal women in South Korea. The research reveals that premature menopause is associated with a higher risk of developing type 2 diabetes, emphasizing the critical role of hormonal changes in metabolic health.
New research reveals that exoplanets with masses similar to Jupiter formed much sooner than previously thought, suggesting the accretion process takes place early. This finding could lead scientists to re-evaluate and revamp their theories of planet formation for the solar system and elsewhere.
A symposium at Lehigh University aims to explore challenges and solutions for improving AI's reliability, inclusivity and ethical impact in healthcare. The event will bring together researchers, clinicians and industry experts to foster cross-disciplinary collaboration and promote people-centered AI-enabled healthcare systems.