A daily oral medication has been shown to lower bad cholesterol levels in people with a previous heart attack or stroke, or those at high risk for one. The study found that participants taking the medication had significant reductions in LDL-C levels and achieved guideline-recommended targets.
Two health tech companies, PolyVascular and Brainomix, won the American Heart Association's Health Tech Competition for their innovative solutions to improve cardiovascular disease and stroke patient outcomes. PolyVascular developed a minimally invasive valve to help children with congenital heart disease, while Brainomix created AI so...
Researchers have discovered how key molecules coordinate chromosome alignment in cell division. Dual inhibition of KIF18A and CENP-E selectively kills cancer cells, suggesting a new therapeutic avenue for cancer treatment. This study highlights the importance of targeting specific proteins to develop more effective anticancer therapies.
Researchers at the University of Pittsburgh have developed a skin patch test that can detect antibodies associated with COVID and flu infections. The test uses carbon nanotubes and is orders of magnitude more sensitive than existing tests.
Research finds that experiencing poverty-level family income over two decades can significantly increase the risk of dying prematurely. Rising unsecured debt is also associated with a higher risk of premature mortality, particularly when debt increases over time.
A new study suggests that chronological age should be considered when creating treatment plans for men with metastatic hormone-sensitive prostate cancer. Older patients are more likely to experience comorbid conditions and die from causes other than prostate cancer.
Researchers found that the leptin-SCD pathway fuels breast cancer growth and motility, leading to poorer recurrence-free survival. Selectively blocking SCD activity can counteract pro-tumorigenic effects driven by leptin, revealing a potential therapeutic target for obese patients.
Renowned gastroenterologist Jean-Frédéric Colombel, MD, will deliver the 31st Anatomy Lesson on November 20, exploring Mount Sinai's pioneering work in IBD prevention and treatment. His presentation aims to highlight the growing problem of immune diseases, including Crohn's disease.
A Duke University study shows that cultural norms influence gesture use, with Black and White Americans communicating differently. The research highlights the importance of considering nonverbal cues to improve understanding across racial groups.
A study found that patients with peripheral arterial disease (PAD) who also have atrial fibrillation (AFib) are at a significantly higher risk of major adverse cardiovascular events, including heart attack, stroke, and death. The presence of AFib nearly doubles the risk compared to PAD alone.
The joint research hub aims to bridge academic research and scalable infrastructure for open AI systems, with a focus on decentralised computing architectures and secure AI marketplaces. Early proof-of-concepts are expected within two years, targeting pilot applications in finance, healthcare, and smart infrastructure.
Researchers at UMC Utrecht are developing a predictive model to accurately predict disease progress in juvenile dermatomyositis. The Interferon Score aims to identify which children can safely reduce medication and which require intensified treatment.
A new UAlbany study finds that Black, Hispanic, and Native American children are significantly more likely to struggle with reading compared to white and Asian peers. The analysis of a nationally representative sample shows these gaps emerge by kindergarten.
A new method of gene editing allows for the efficient production of non-GMO, genome-edited plants without introducing foreign DNA. The technique uses Agrobacterium-mediated transient expression to enable genome editing in a transgene-free manner.
Researchers from Chung-Ang University have developed a novel AI-based approach for producing high-fidelity and defect-aware ultrasonic images, outperforming traditional techniques. This technology has the potential to revolutionize non-destructive testing in industries such as semiconductors, energy, and automotive.
A new study reveals a significant accumulation of microclots in Long COVID plasma, driven by excessive NETs production. This interaction may become pathogenic when dysregulated, suggesting underlying physiological interactions between microclots and NETs.
A new method uses uranium-lead dating and elemental mapping on dinosaur eggshells to accurately determine the age of fossil sites. This technique overcomes limitations in dating fossils themselves or associated minerals, providing a powerful tool for paleontologists to unravel mysteries about dinosaur evolution.
A new study found that babies as young as 7 months old can quickly recognize their mothers' voices, but struggle with unfamiliar ones. Maternal speech may also play a role in shaping social processing, influencing how babies respond to new faces.
A clinical trial found that ivermectin can be safely given to young children weighing as little as 5 kilograms, challenging existing manufacturer restrictions. The study's results could spur progress against diseases like intestinal worms, scabies, and river blindness.
The collaboration combines Insilico's Pharma.AI platforms with Lilly's expertise to discover and advance new therapies. Insilico will utilize its platform to generate candidate compounds, accelerating the development of transformative treatments for urgent patient needs.
Researchers at NYU found that teacher autonomy, peer collaboration, and collective responsibility positively impact academic achievement for English learners. Schools with greater levels of these factors earned their students more high school credits.
Researchers found a link between platelet aggregation and Alzheimer's biomarkers in midlife, suggesting a potential early warning sign. The study analyzed 382 participants and found that stronger platelet clumping was associated with higher levels of amyloid and tau proteins.
A new study found that people often misperceive the environmental impact of everyday food products, with common misconceptions including overestimating processed foods and underestimating water-intensive products. The researchers suggest that clear labels could help consumers make informed sustainable choices.
A team of engineers at Rice University has developed a cleaner approach to recycling lithium-ion battery waste by recharging the cathode materials. The process produces high-purity lithium hydroxide with minimal energy consumption, making it a promising solution for sustainable battery production.
A study found that reducing amino acids methionine and cysteine in lab mice' diets led to significant weight loss through increased thermogenesis, similar to cold-induced methods. The research team believes this could be a promising approach for obesity treatments and developing functional food products.
A new study suggests that catheter ablation can reduce the risk of stroke in people with atrial fibrillation (AFib) and may even allow them to stop taking blood thinners. The study found that long-term oral anticoagulation is not necessary after successful ablation in patients with moderate to high stroke risk.
Researchers studied mechanical properties of solids as a function of grain size and boundary thickness, revealing that thick boundaries improve strength and ductility in single-component face-centered cubic materials. However, for other materials, increasing boundary thickness softens the material due to dislocation-dominated plasticity.
Autoimmune hepatitis is often associated with other autoimmune conditions, including thyroid disease, type 1 diabetes, inflammatory bowel disease, and rheumatologic disorders. The study highlights the need for precise diagnostic criteria and interdisciplinary management strategies to optimize outcomes in patients with multi-organ autoi...
Sanjay Rajagopalan, a leading expert in cardiovascular medicine, has been recognized for his pioneering work on the impact of environmental risk factors on heart health. His research has informed public health policies worldwide and led to new understanding of how air pollution affects cardiovascular health.
Avram Miller, a renowned scientist and innovator, has been appointed as the first IIT Fellow, marking a new initiative to recognize leading figures in science and innovation. The program aims to foster collaborations with prominent experts worldwide, strengthening IIT's global reputation.
A federally funded clinical trial tested an intervention to prevent suicides among people recently released from jail, reducing suicide attempts by over half. The safety planning intervention involved in-jail programs and telephone check-ins for six months.
Researchers from NUS Medicine and CHA University have developed AI-assisted diagnostic tools for male infertility, identifying hidden patterns in clinical data. A novel compound, MIT-001, has been shown to reverse age-related embryo decline by targeting ferroptosis, a form of cell death driven by iron and oxidative stress.
A comprehensive study published in Otolaryngology–Head and Neck Surgery reveals a strong link between type 2 diabetes and hearing loss. The research found that individuals with diabetes face a significantly elevated risk of hearing loss, with the prevalence ranging from 40.6% to 71.9%.
Allergist Cherie Zachary, MD, was installed as president of the ACAAI, replacing David Stukus, MD. Dr. Zachary brings experience in leadership and equity initiatives to her role.
Researchers at the University of Cincinnati have developed a new technique to treat cancer by altering the physical structure of subcellular organelles, specifically lipid droplets. By grouping and locking up lipid droplets, they can starve cancer cells of energy, slowing tumor progression.
Researchers identified 32 common differentially expressed genes involved in IA, including NGFR and SERPINE1, which may serve as biomarkers. The study suggests that understanding the involvement of aging-related genes can aid in developing therapeutic strategies to minimize surgical interventions.
Researchers developed green-synthesized cerium oxide nanoparticles that combined cidofovir with nanoceria, enhancing anticancer activity and binding affinity to DNA and RNA. The new compound destroyed over 97% of cancer cells, suggesting a promising candidate for future cancer therapies.
The MRC Laboratory of Medical Sciences launches its innovative Team Science initiative to address major challenges in human health. Two projects focus on ageing and sex differences, exploring inflammation, reproductive health, and infertility through a transdisciplinary approach.
The FDA has revised the labeling for menopausal hormone therapy based on current evidence, which may affect patient safety and treatment options. The updated guidelines aim to provide more accurate information for healthcare providers and patients.
The new clinical cancer research center will support lung and genitourinary cancers, serving as a central hub for seven VA medical centers. The grant aims to improve access to precision oncology trials and patient care for veterans diagnosed at later stages.
Child abuse and neglect rates in the US have declined overall over the last decade, but disparities persist, particularly among Black children and female children. Poverty is identified as a critical target for intervention, and strengthening government financial assistance programs can help reduce disparities.
Researchers at KAIST have developed a new technology called SHARE that can reconstruct high-quality 3D scenes using only ordinary images without precise camera pose information. This breakthrough enables rapid and precise reconstruction in real-world environments without additional training or complex calibration processes.
A cross-sectional study found significant associations between state-level firearm ownership and all-cause and firearm-specific homicide among pregnant women. The results suggest that prevention efforts should focus on women during pregnancy, particularly in states with higher firearm ownership rates.
Researchers used single particle spectroscopy to study how cyanobacteria protect themselves from too much sunlight. They found that a shared mechanism, called the orange carotenoid protein, binds to distinct but specific sites in different phycobilisome architectures, providing similar protection.
A study by Kahori Kita and colleagues at Johns Hopkins University found that switching between movement patterns is difficult, especially for newly learned motor skills. However, with practice, participants improved their ability to switch between movements. The researchers hope to further explore how these memories are retrieved.
Researchers found that an earlier blood transfusion may reduce the risk of heart failure and irregular heartbeat in adults with heart disease. The study suggests that waiting until hemoglobin levels are low before transfusing blood may not be the best strategy for high-risk patients.
A new native bee species named Megachile (Hackeriapis) lucifer has been discovered in the Bremer Range region of Western Australia. The striking bee was found visiting both an endangered wildflower and a nearby mallee tree, and its discovery highlights the importance of understanding native bees before their habitats are disturbed.
Ordene Edwards explores how motivation can improve retention and academic success among engineering students. The study aims to help students see the value in their studies, increasing engagement and persistence.
Scientists at Southwest Research Institute (SwRI) have successfully replicated induced Pluripotent Stem Cells (iPSCs) using a new application of their cell-expansion bioreactor. The bioreactor's unique geometry allows for the growth of large quantities of iPSCs, which can differentiate into any other cell type in the body.
A collaborative research team is studying how photosynthetic cells retain 'heat stress memory', a key adaptive mechanism that could help crops withstand intense heat waves. The team aims to decode this process using genome-scale and high-throughput approaches.
A recent study from Karolinska Institutet has identified a specific protein pattern in the blood that may reflect an increased risk of hereditary atherosclerosis. The research found that certain proteins, such as follistatin and cathepsin D, are significantly elevated in people with a family history of early-onset coronary heart disease.
Researchers designed a self-powered, compact tactile interface using an MXene/Bi 2D heterojunction. The device combines sensing, encoding, and low-power readout, achieving high sensitivity, fast response, and durability.
The study reveals fundamental physical principles underlying bacterial FM signal processing, demonstrating that FM decoding mechanisms increase information entropy by approximately 2 bits compared to traditional AM. A simplified cAMP signaling pathway was reconstructed using a light-controlled system, enabling precise monitoring of fre...
The $12.25 million NSF grant will fund the development of an advanced system prototype and tools for automation, remote data control, and scientific workflow management. The project aims to support the establishment of data centers in the region and provide access to these resources to researchers nationwide.
Researchers found that popular AI models, such as large language models (LLMs), are prone to discrimination and fail critical safety checks. This poses a significant risk to robot safety, particularly in settings where vulnerable individuals are involved.
Over the past two decades, nearly half of US states have reported firearm mortality as the leading cause of death in children aged 1-19. Gun violence has become the primary cause of death for this age group, with Alaska being the first state to report this trend in 2004.
Researchers found that people with high blood pressure who took a daily chance to win cash were more likely to take their medication consistently. However, they did not achieve significantly better blood pressure reductions compared to those without financial incentives. The study suggests that improving long-term behavior changes is c...
A new study found that people with generalized anxiety disorder, panic disorder, and social anxiety disorder have lower levels of choline in their brains. Choline is vital for cell membranes and brain functions like memory, mood regulation, and muscle control.
A new gradient anode design addresses key challenges in sodium batteries, achieving high-energy-density and stable performance. The symmetric cell demonstrates ultralong cycle life and unprecedented energy density of 200 Wh kg-1.
A new study found that using a simplified clot-preventing medication regimen for one month after stent placement in adults with atrial fibrillation is equally safe and effective as a standard year-long treatment regimen. This approach may help reduce bleeding risk associated with the medications while maintaining stroke, heart attack, ...