A study by the University of Kansas found that Kansas City's zero-fare bus policy attracted 17% of respondents who started using bus service, particularly among younger people and white residents. The policy also increased overall bus use, with new users without vehicle access making more trips per week than those with access.
Researchers at UTA are exploring the potential of zinc to protect and regenerate muscle tissue damaged by trauma, with a focus on reducing secondary damage. The study uses a zinc-infused gel to promote muscle regeneration following blast injuries and aims to identify a safe and convenient way to apply zinc directly to muscle tissue.
Scientists at the University of Pittsburgh have created phages with synthetic genetic material, allowing them to add and subtract genes. This breakthrough enables researchers to engineer phages to target specific bacteria, offering new hope for combating antibacterial resistance.
Researchers found that regional differences in environmental conditions, rather than diet quality, drive divergent health trends in California Sea Lions. Despite similar diets, populations in Mexico are declining while those in the US are thriving.
The inaugural Margot and Tom Pritzker Prize for AI in Science Research Excellence recognizes outstanding contributions to the intersection of artificial intelligence and scientific research. Winners Kyle Cranmer and Deborah Marks were honored for their pioneering work in simulation-based inference and language modeling methods.
The study reveals how chemical sensors discriminate among various odorant molecules using explainable AI, enabling the selection of receptor materials for high-performance sensors. This breakthrough advances understanding of human olfaction and paves the way for practical application of artificial olfaction technology.
Researchers used a tool to measure pre-speech communication skills in infants with neurogenetic syndromes, including Down, Angelman, and Fragile X. The study found developmental differences among the groups, which may offer clues to better understanding and treatment of these conditions.
AcCELLerate has partnered with ATCC to provide customized Master, Working, and assay-ready instaCELL banks for research clients. Researchers will gain access to high-quality, authenticated cell lines with increased assay reproducibility.
Researchers found that taking metformin in addition to standard care after catheter ablation reduced episodes of atrial fibrillation in people with obesity. The study suggests that lifestyle and risk factor modification efforts can be aided by metformin, and future studies are needed to confirm these findings.
Astronomers have successfully installed lasers on the eight-metre telescopes at Paranal, enabling the creation of an artificial star to correct atmospheric blur. This upgrade unlocks a greater observing power and wider sky coverage for the VLTI, allowing for deeper observations of faint targets.
A team of researchers has identified a common sex-determining gene called ANTSR in both bees and ants, revealing a conserved mechanism that has been present for over 150 million years. This finding sheds light on the genetic basis of sex determination in these species and may have implications for bee conservation and breeding programs.
A new report from the University of Liverpool highlights the uneven progress toward achieving UN SDG11, a goal to make cities more inclusive, safe, and sustainable. To meet this goal by 2030, planners must translate global awareness into local action.
Researchers at ISTA quantify the environmental impact of international conference travel, finding that train travel can significantly reduce carbon emissions. The study shows that traveling to an overseas conference generates a substantial carbon footprint of four to five tons per participant.
In a Phase 1 clinical trial, CRISPR-Cas9 gene-editing therapy CTX310 reduced LDL cholesterol and triglycerides by nearly 50% on average, achieving large reductions in both for the first time. The treatment has shown promise as a one-and-done approach to transform care for patients with lifelong lipid disorders.
The American College of Medical Genetics and Genomics has published a new clinical practice resource guiding clinicians in managing individuals with heterozygous germline pathogenic variants in RAD51C, RAD51D, and BRIP1 genes. The resource provides evidence-based recommendations on personalized risk assessment, surveillance, and risk-r...
Studies found that medical and recreational cannabis dispensary openings led to significant reductions in opioid prescriptions for chronic and acute pain management. The findings suggest a safer alternative to opioids for managing pain, particularly for cancer patients.
Researchers found that large language models exhibit systematic biases when evaluating texts, but only when the source or author is revealed. The studies showed a high level of agreement among models when no information was provided, but decreased agreement and even bias emerged when fictional sources were used.
Researchers developed a Climate BioStress model to detect biological signatures of climate change. A Sentinel System (CBS3) is proposed to track climate stress indicators across biological, built, and social infrastructures.
A recent study found that adults with heart disease who took vitamin D doses tailored to their individual needs reduced their risk of another heart attack by more than half. The study also showed that supplementation appeared beneficial for preventing heart attack specifically.
Researchers propose that interactions between particles in primordial matter domination could have given rise to the first black holes, boson stars, and cannibal stars. These compact objects could have formed through gravothermal collapse, leading to surprising cosmic structures.
A PhD student at Lehigh University is working with Siemens to develop real-time monitoring and control tools for hyperscale data centers. The goal is to create a localized power network that can operate independently of the main grid, reducing power demands from artificial intelligence and increasing energy efficiency.
Researchers at Sanford Burnham Prebys Medical Discovery Institute found that aging accelerates pancreatic cancer progression, leading to faster tumor growth and metastasis. By understanding the impact of age on the tumor microenvironment, they developed a new approach to treating this disease in frail patients.
Astrophysicists used simulations to uncover the missing piece that previous studies had overlooked: magnetic fields. They found that strong magnetic fields can slow down a black hole and carry away some of its stellar mass, creating lighter and more slowly spinning black holes.
A fully digital AI zero-cost method for detecting dementia has been developed and tested in a randomized clinical trial, increasing new diagnoses by 31% compared to usual care. The method combines a patient-reported tool with an artificial intelligence algorithm analyzing existing clinical data.
A study published in Molecular Cancer suggests that blocking the thyroid hormone receptor Beta, TRβ, can inhibit the growth of prostate cancer cells. This discovery may lead to a new way of treating certain types of aggressive prostate cancer.
The CONCERT project aims to understand how light determines molecular evolution and control photochemical reactions by deflecting molecule paths. This could lead to green chemistry advancements and design of photosensitive molecules and photonic devices.
Adults with atrial fibrillation who drank a daily cup of coffee were 39% less likely to have an irregular heart rhythm episode compared to those who avoided all caffeinated products. The preliminary study results suggest that caffeinated coffee may not be responsible for raising the risk of AFib and may even reduce it.
A new study found that standard medical care, including blood thinners, is the better choice for older people with irregular heart rhythms who are at high risk of stroke and bleeding. The catheter-based procedure was non-inferior to medical therapy in reducing stroke risk but caused more bleeding in higher-risk patients.
Researchers discovered psilocin's mechanism to reduce alcohol use in female mice by dampening activity of neurons in the central amygdala, leading to decreased drinking. This finding provides mechanistic insight into psychedelic treatment for psychiatric disorders like depression and anxiety.
The study found that sand mining in the Mekong River is causing a decline in the reverse flow system that feeds water into Tonlé Sap Lake. The lake is home to 885 species and provides livelihoods for almost two million fishers, but its future is at risk due to the increased extraction rates.
Researchers discovered a connection between sugar metabolism and alcohol addiction, identifying ketohexokinase (KHK) as a key enzyme involved in the process. Blocking KHK showed reduced alcohol consumption and liver damage in mice, suggesting a potential new treatment for both conditions.
Scientists studied Neanderthal DNA to understand how facial features develop and evolve. They found a region of DNA that activates the SOX9 gene, leading to a larger lower jaw in Neanderthals. This discovery sheds light on the genetic mechanisms behind face variation and evolution.
Researchers from the University of Florida discovered critical security vulnerabilities in portable genetic sequencers, exposing them to potential attacks and data breaches. The devices' reliance on insecure connections to laptops or unsecured networks amplifies these risks.
A new dietary supplement made from oat protein nanofibrils coated with iron nanoparticles has been developed to efficiently treat iron deficiency and anaemia. The supplement is not only effective but also easy to produce and suitable for vegans and vegetarians, offering a stable and high-absorption iron delivery platform.
A new AI-based approach analyzes XAS data to identify material properties, providing objective insights for rational material design. The method achieved high accuracy and revealed meaningful variations in electronic states.
The study found that AI's rapid growth would annually put 24-44 million metric tons of CO2 into the atmosphere, draining 731-1125 million cubic meters of water. A roadmap suggests using smart siting, faster grid decarbonization and operational efficiency to cut impacts by 73% (carbon dioxide) and 86% (water).
A new study reveals that human disturbances, such as logging and wildfires, are profoundly impacting the Amazon rainforest's ecological functions and evolutionary history. The researchers found that even sustainable management practices, like selective logging, have significant negative impacts on tree diversity.
Researchers used molecular dynamics simulations to investigate how polyamides adhere to alumina surfaces, finding that adhesion strength depends on polymer chemistry and surface termination. The study offers practical design guidelines for selecting surface treatments and polymer types, enabling the creation of stronger, lighter joints.
Chameleons have two long, coiled optic nerves that enable their remarkable ability to look in two different directions at once. Researchers used CT scanning technology to visualize the hidden structure, revealing a unique trait not seen in any other lizard.
Climate changes in Lake Turkana influenced fault activity and magma production, rewriting the story of human evolution. Researchers found that lower lake levels led to increased melting and faulting, with potential implications for future volcanic and tectonic activity in East Africa.
A new study warns that the quiet abandonment of conservation projects is undermining global biodiversity and carbon targets. At least one-third of conservation programs are abandoned just a few years after implementation, compromising progress announced at events like COP.
A liquid biopsy test may enable early detection of various cancers, increasing stage I–III diagnoses by 10-30% and stage IV diagnoses by 45%. This could improve patient outcomes and reduce the economic impact of cancer. The study's findings suggest a game-changing approach to cancer control.
A new nasally-delivered vaccine has been shown to prevent severe disease and curb bacterial transmission, addressing a global need for next-generation immunisation technologies. The vaccine targets the respiratory mucosa, providing stronger protection against respiratory infections.
Researchers from Okinawa Institute of Science and Technology have catalogued the science behind Bashofu textiles, which have kept Okinawans cool for over 500 years. The study reveals the unique properties of Musa balbisiana var. liukiuensis fibers, including a honeycomb structure that effectively leads sweat away from the skin.
A new study by Curtin University predicts that invasive cane toads will colonize up to 75% of the Pilbara within three decades, putting 25 native species at risk. Simple steps can prevent the toads from using dams as stepping stones into the region.
A new study explores how emotions play a crucial role in communicating natural disasters, finding that balancing fear with positive emotions like fascination and confidence can improve disaster preparedness. The research highlights the importance of recognizing and channelling emotions to promote self-efficacy and motivation.
A Portuguese theatre company collaborated with doctors and patients to develop a play about bipolar disorder, which was performed in front of an audience of over 300 people. The play's emotional engagement helped facilitate the assimilation of scientific information and contributed to reducing stigma surrounding mental illness.
A new study has discovered a strong link between chronic fatigue syndrome and abnormal breathing patterns, which may be worsening symptoms. Dysfunctional breathing was found in nearly half of the patients, with 71% experiencing breathing problems during exercise.
TorchSim, a PyTorch-based simulation engine, delivers acceleration for MLIPs by unifying molecular dynamics and gradient-based learning. The platform provides speed, flexibility, and ease of integration with emerging machine learning atomistic models.
A new study found that failing to degrade maternal mRNAs triggers genomic traffic jams in mouse embryos, halting development at the first step. The research team discovered that increased chromatin accessibility and abnormal transcription regulation lead to R-loop formation, causing replication stress and DNA damage.
Researchers found that tubeless anesthesia significantly reduces postoperative complications, promotes enhanced recovery, and lowers costs in selected patients. The study also showed improved respiratory function and reduced intubation times.
The double degree program aims to cultivate global talent equipped with world-class expertise and technology. Students will study at both universities, earning bachelor's degrees from Okayama University of Science and Minghsin University of Science and Technology upon completion.
Researchers found that Biaxially rotational dynamic radiation therapy (BROAD-RT) significantly reduced radiation doses to lungs, heart, and oesophagus compared to volumetric modulated arc therapy (VMAT). However, it resulted in greater low-dose lung exposure.
A new study published in iMetaMed uses single-cell Raman spectroscopy to track biochemical changes in mouse oocytes as they age, revealing a decline in metabolic maturity. The research suggests that mitochondrial dysfunction plays a key role in the age-related decline of egg cell quality.
A new study finds that rare and common genetic variants counterbalance each other to maintain telomere stability. The researchers used data from 379,764 participants and found a compensatory genetic mechanism that prevents extreme shortening or lengthening of telomeres.
A CT-based whole-lung radiomic nomogram accurately identifies AECOPD, offering a robust tool for clinical diagnosis and treatment planning. The nomogram demonstrated near-equivalent diagnostic performance to the radiomic score model, surpassing that of the clinical model.
A global dataset of orchid-fungal associations reveals that an orchid's fungal community is driven more strongly by its ecophysiology and biogeography than by its phylogeny. The study provides new insights into the global patterns and drivers of orchid mycorrhizal interactions.
Researchers have introduced a ferroelectric BaTiO3 nanoparticle coating to enhance the high-voltage stability of chloride solid electrolytes. This coating modulates interfacial electric fields, significantly improving oxidative stability under ultrahigh voltage.
The Rad51 protein plays a crucial role in connecting DNA damage repair, tumor progression, and immune regulation. Dysregulation of Rad51 can alter immunogenicity of tumor cells, affecting cGAS-STING innate immune pathway and Programmed Death-Ligand 1 (PD-L1) expression.
This study analyzed the temporal evolution of three LLMs in oncology, finding that subjective questions degrade faster over time than objective queries. The results highlight the need for ongoing performance monitoring and strategies to integrate up-to-date clinical data for safe and reliable AI deployment in cancer care.