A new study highlights the significant role of quality of dietary fat, rather than total amount consumed. Research reveals that palmitic acid can promote toxic bioactive lipids and low-grade inflammation, while oleic acid may have a protective effect against metabolic disorders.
Early humans at the Acheulian site of Gesher Benot Ya'aqov relied on driftwood from lakeshore environments for fuel, suggesting a practical and efficient strategy. This approach may have been a decisive factor in their choice of location.
A new study introduces Map the Giants, a pioneering citizen-science initiative to document giant coral colonies before they disappear due to global pressures. The project aims to unlock genetic secrets and traits of resilient corals, providing a validated sampling frame for future research.
Recent progress in advanced energy manufacturing highlights 3D printing's potential to redefine next-generation lithium batteries. The technology enables precise control over three-dimensional structures, improving ion-transport pathways and mechanical robustness.
A team of scientists from NTU Singapore has developed a new biochip that, when paired with Artificial Intelligence (AI), can detect quickly and accurately extremely small amounts of microRNAs. The device can cut detection time from hours to 20 minutes.
Alexandra Z. Worden, a leading expert in ocean biogeochemistry, has been awarded a Guggenheim Fellowship to deepen understanding of microbial responses to photosynthetic algae sinking to the seafloor, removing carbon dioxide from the atmosphere and impacting dark ocean communities.
The hospital is conducting a phase 2 clinical trial evaluating STAR0602, which activates the immune system to stop tumor growth across various cancers. The goal of this study is to identify safer and more effective treatments for people with advanced cancers.
Researchers developed a new AI-assisted tool called CacheMind to improve cache performance and reduce evictions. The tool uses causal reasoning to analyze fine-grained details about system behavior, enabling computer architects to identify patterns and implement fixes.
Researchers propose a new approach to secure optical communication by hiding information in the physical structure of light, making it difficult for unauthorized parties to intercept or decode. Computer simulations showed that the method can transmit information reliably without revealing it through changes in beam size or intensity.
Researchers from Shandong Second Medical University and Wuhan University identified LINC00862 as a tumor suppressor that forms a triplex-mediated transcriptional activation driving tumor suppression in HCC. The study reveals a bidirectional regulatory loop between LINC00862 and RBM47, which reinforces tumor suppression.
Researchers found that post-fire seedling establishment remained strong across key commercial species, Scots pine and birch, after combining prescribed burning with tree retention. Natural tree regeneration met or exceeded commercial standards, supporting biodiversity goals with sustainable forest management.
Researchers have finally understood why reinforced rubber is so tough and durable, with tiny particles forcing the material to fight against its own incompressibility. This breakthrough could improve tire design and lead to safer, longer-lasting products.
Researchers create living biohybrid miniature robots that solve traditional engineering trade-offs between structural rigidity and environmental adaptability. These biological engines utilize embodied intelligence to navigate complex terrains and achieve performance metrics rivaling state-of-the-art synthetics.
Scientists mapped the spread of a novel flu strain, D1.1 H5N1, through wild bird populations across North America, revealing its emergence and geographic penetration. The study shows that current human vaccine stockpiles will likely work well against both avian and human infections.
Using three-dimensional electron diffraction, researchers demonstrate that electrons can provide averaged structural information previously accessible only with X-rays. They also optimize the electron dose and develop tailored acquisition strategies to probe highly sensitive nanocrystalline structures while preserving the material.
A new gene catalogue provides comprehensive insights into premature aging disorders, highlighting the central role of genome maintenance and DNA repair pathways. The catalogue organizes genetic and clinical information for 56 syndromes and 160 distinct clinical entities, offering a valuable framework for future research.
Researchers found that faces presented behind observers are perceived as more emotionally intense than those in front. This 'behind-enhancement bias' is observed even when participants view the face via a virtual mirror without turning around. The study suggests a spatially modulated perceptual bias related to processing of emotionally...
Researchers found associations between BRCA1/2 pathogenic variants and four types of cancer: thyroid, bladder, skin, and head and neck. Pathogenic variants in BRCA1 increase thyroid cancer risk, while BRCA2 increases risk for bladder, head and neck, and skin cancers.
A community-based point-of-care HCV RNA testing program was feasible and led to a high percentage of same-day treatment for American Indian and Alaska Native participants. The study supports expanding point-of-care HCV RNA testing and integrated treatment to advance HCV elimination.
The American Gastroenterological Association has announced its 2026 recognition prize recipients, including Hashem El-Serag for the Julius Friedenwald Medal for his exceptional service to the field and AGA. Dr. El-Serag is an internationally recognized physician-scientist known for pioneering epidemiologic research on hepatocellular ca...
A notable minority of US youth and young adults, particularly those facing structural disadvantages and mental health distress, engage in intentional online searches for gun-related harm. Public health strategies combining digital interventions with structural reforms offer promise to reduce gun-related harm among vulnerable populations.
Researchers found that active mitochondria keep dendritic cells ready to respond by maintaining key internal processes. Disrupting this balance alters DNA methylation patterns at regulatory regions, enabling rapid gene activation.
Researchers proposed a dynamically expandable learning framework for interactive trajectory prediction to enable models to adapt to evolving traffic environments. The approach effectively mitigates catastrophic forgetting and maintains stable predictions for critical interaction scenarios across multiple learning stages.
Scientists have pioneered a way to make integrated circuits for light by depositing complex patterns of specialized materials onto silicon wafers. This advance could provide a big boost for emerging technologies such as artificial intelligence, quantum computers, and optical atomic clocks.
A new study found that AI applications enhance consumer understanding of skin conditions by increasing accuracy and confidence. However, imperfect guessing accuracy remains, highlighting the need for further design improvements to facilitate better comprehension.
A massive study of ancient DNA from nearly 16,000 people across over 10,000 years in West Eurasia reveals that natural selection has shaped modern human genomes more than previously thought. Many gene variants linked to health and complex traits have been selected since farming began.
An international team of scientists has established a formal scientific definition for 'Blue Zones', a term previously used to describe places where people live the longest. The new criteria capture two key benchmarks: unusually strong longevity after age 70 and high odds of reaching 100, conditional on surviving to 70.
Researchers developed MitoCatch, a system that targets disease-affected cells with healthy mitochondria. The innovation enables efficient cell type-specific mitochondrial delivery, improving survival of damaged neurons in vitro and retinal ganglion cells in vivo.
Researchers developed a novel approach to personalize travel behavior analysis without centralizing sensitive user data. The IPC-FM framework achieves high accuracy and adapts quickly to new users, offering a customizable solution for individual mobility needs.
Researchers identified a CRISPR variant that distinguishes tumor DNA from healthy DNA and selectively cuts the former. This method relies on methyl groups attached to DNA, which are altered in cancer cells.
A study from Columbia University Mailman School of Public Health found that Epstein-Barr virus and a specific immune-related gene interact to shape disease risk. The research identified a key interaction between the human HLA allele HLA-A*11:01 and a viral variant in the EBV gene EBNA3B, elevating nasopharyngeal cancer risk.
Researchers at Boston Children's Hospital have identified a mechanism for immune cells to recycle defective or autoreactive antibodies by editing their genes. The new process uses an enzyme called RAG to swap out light chains with nearby new ones, often making them non-defective and functional.
Scientists have tracked oxygen spillover in catalysts using environmental transmission electron microscopy and observed bulk oxygen spillover for the first time in Ru/rutile-TiO2 catalysts. The research provides new approaches for utilizing catalyst bulk, enabling it to contribute to mass transfer during catalytic reactions.
The JAMA+ Trials platform provides a comprehensive online space for clinical trial research, featuring multimedia content and tailored resources. Recent trials published across multiple JAMA Network journals are highlighted on the platform.
Researchers developed a platform called PerturbFate to map genetic variations and identify common control points driving changes in cell behavior. The study shows that targeting these shared regulatory nodes can lead to combination therapies for complex diseases like cancer, with potential applications beyond melanoma drug resistance.
A large DRUP trial reveals that existing targeted cancer therapies can deliver profound and durable benefits, even in heavily pretreated or rare cancers. About one-third of patients responded to treatment or had stable disease for at least four months.
A new study developed a multi-scale dynamic driving environment to assess the impact of daily driving behavior on electric vehicle battery health. The framework uses deep reinforcement learning to optimize battery health and energy efficiency, and its results show that stable driving behavior can extend battery lifetime by approximatel...
Social media use has been linked to psychological distress and impaired functioning in some people, but the impact varies widely depending on how and why it's used. Researchers are debating how to measure social media addiction and need more rigorous studies to determine whether it should be classified as a clinical disorder.
A new study introduces the diameter-transformed fluidized bed (DTFB) reactor, which addresses national demands for upgraded automotive gasoline quality and advanced heterogeneous catalytic reactions. The DTFB platform achieves precise selectivity control for complex catalytic reactions in a single fluidized bed.
Researchers propose a novel latency-aware trajectory prediction framework, LatenAux, empowered by a consolidated auxiliary learning paradigm. The framework transforms latency from a hindrance into an opportunity for improved performance. Extensive experiments validate its effectiveness and superiority.
KEPT, an AI system, combines video understanding with a memory of similar past scenes to help self-driving cars predict their own short-term path more safely. The system uses a fast and lightweight retrieval module to reduce prediction errors and potential collisions.
Researchers from China Mobile Research Institute and ZGC Institute outline a comprehensive analysis of cooperative integrated sensing and communication (ISAC), a key paradigm for sixth-generation mobile information networks. The study presents real-world field trial results, demonstrating the technology's feasibility in various setups.
A study in Engineering explores a novel strategy for multi-user edge computing systems to maximize robot swarm lifetime. By exploiting correlation among distributed data sources, the approach reduces communication overhead and energy drain, extending swarm operation by up to 650%.
A new artificial intelligence framework called SS-MA-PPO treats mandatory lane-change control as a coordinated multi-agent problem, enabling CAVs to effectively coordinate with surrounding vehicles. The framework consistently delivered the best performance in terms of delay, waiting time, fuel consumption, and stop-and-go frequency.
The report highlights a critical implementation gap in digital mental health tools, which struggle to reach the masses due to inadequate infrastructure. The industry has excelled in creating evidence-based tools and AI systems, but fails to deliver them at population scale without proper systems in place.
The award recognizes the book's significant contributions to research, teaching, business, and industry in the field of optics and photonics. The authors, Thomas Luhmann, Stuart Robson, Stephen Kyle, and Jan Böhm, are renowned experts in photogrammetry and 3D imaging.
Researchers developed a simple, 15-minute test to measure melatonin levels using fluorescent nanoparticles and smartphone-based readers. This technology can aid in monitoring circadian rhythms, crucial for shift workers and space operations.
Researchers at Case Western Reserve University will use AI and machine learning to analyze over 1,800 potential genes that have been identified as suitable new targets for treating Alzheimer's disease. The goal is to deliver a prioritized list of genetically validated drug targets to pharmaceutical developers and clinicians.
Researchers at KAUST have discovered that depleted oil fields can be used to store hydrogen in a safe and efficient manner. This method involves incorporating hydrogen into carbon-based molecules called Liquid Organic Hydrogen Carriers (LOHCs), which can then be stored underground and extracted to recover residual oil.
The Cancer Dependency Map Consortium is launching Phase 3 to expand its research beyond cancer vulnerabilities to investigate resistance and surface targets. The consortium aims to develop novel oncology targets and biomarkers for the next generation of cancer therapies.
Researchers at Northwestern University have developed a single-step process to turn methane into methanol without high heat and pressures. The method harnesses tiny bursts of plasma to break the chemical bonds in methane, producing a cleaner-burning fuel for ships and industrial boilers.
A survey found 84% of primary care patients are unfamiliar with Alzheimer's blood tests, but 85% would take one if recommended. Patients value education and ease of use, and express concerns about test reliability and cost.
Researchers develop fluoride-engineered perovskite nanocrystal glass for high-efficiency, full-color emission and ultra-high-resolution holographic displays. The glass matrix enables stable and efficient photoluminescence of PNCs, driving the creation of high-quality dynamic displays.
The organization welcomes Craig Bower, Allison Hirsch Hadar, Susan Johnson, Andrew Schillaci, and Ed Warshauer to its Board of Trustees, succeeding outgoing members. These new leaders join a mission primed for global impact, signaling a reinforced commitment to accelerating safe, effective, and targeted therapies.
A recent study found that academic burnout is associated with increased internet gaming and depression in Chinese adolescents. The study highlights the importance of targeted prevention strategies, including mental health check-ups, counseling sessions, stress management programs, and attentional bias modification training.
Intensifying ocean eddies are amplifying climate extremes in key coastal ecosystems by redistributing heat and nutrients. This process enhances productivity in some areas while trapping heat closer to the surface, leading to rapid warming and altered regional weather patterns.
Engineers at Northwestern University developed artificial neurons that generate realistic electrical signals to activate living brain cells. This breakthrough paves the way for brain-machine interfaces and neuroprosthetics, as well as more efficient brain-like computing systems.
A new study by Cornell University suggests that animal and human waste could meet 102% of nitrogen and 50% of phosphorus needs for US agriculture, reducing reliance on synthetic fertilizers. However, implementation challenges such as processing and transport need to be addressed to unlock this potential.
A new study reveals that cancer cells may begin escaping therapy much earlier, triggered by a stress response that drives them into a temporary drug-tolerant state. Researchers identified an early molecular trigger: NF-κB, which acts as a regulator of cellular stress and survival.
A new blood test identifies African Americans carrying high-risk APOL1 variants at risk of developing kidney failure years before clinical symptoms appear. The test uses circulating protein markers linked to kidney injury and fibrosis, outperforming existing clinical prediction tools.