The European Centre for Disease Prevention and Control estimates that between 2.4 and 4.1 million people in the EU/EEA are living with chronic hepatitis B infection. The prevalence varies significantly across countries, with the highest rates found in southern and eastern Europe.
Researchers have developed RoboChem Flex, a versatile and modular autonomous synthesis robot that reduces costs to $5000. The system offers human-in-the-loop analytics, Bayesian optimization, and integration with various analytical instruments, making it accessible to laboratories of all sizes.
Researchers use a meteorite resembling Mercury's chemical makeup to recreate the planet's conditions, finding that sulfur lowers the temperature at which magma begins to crystallize. This process reveals how Mercury's low iron content and high sulfur levels shape its interior evolution and crust formation.
The University of Bonn's new Emmy Noether Group is developing AI methods to fuse different types of geodata for a uniform representation. This allows AI to better understand places, leading to precise urban quality-of-life analysis and environmental assessments.
Researchers have combined ion pumps with click-to-release chemistry to enable precise electronic control of drug release for a broader range of therapeutics. This technology allows for targeted local therapy with lower doses, reducing side effects.
A recent JAMA paper identifies key symptoms and signs that strongly indicate a child has sustained a concussion. Common symptoms include headache, dizziness, mental fog, nausea, sensitivity to light and noise, and difficulty remembering.
Researchers developed a new training technique, HarmonyGNN, to improve the accuracy of graph neural networks in heterophilic graphs. The framework achieved state-of-the-art performance on four heterophilic graphs with accuracy improvements ranging from 1.27% to 9.6%.
A new review paper reveals that land surfaces in humid monsoon regions shape precipitation characteristics through complex interactions. High-resolution satellite observations and convection-permitting climate models reveal a nuanced understanding of surface moisture, energy balance, and atmospheric dynamics. This challenges the tradit...
A new study reveals that using reversible words in marketing messages can significantly impact how confident consumers feel about believing a claim. Researchers found that when words differ in their reversibility, it can trigger different mental processes when consumers evaluate marketing language.
Researchers found that introducing new objects in a nonsocial environment reduced fentanyl intake over time and helped rats stop seeking the drug faster. Enriched environments also showed lower levels of stress hormones, linked to relapse in standard conditions.
A new study found that naloxone may not be sufficient to reverse respiratory depression caused by potent synthetic opioids like fentanyl and sufentanil. The study's findings raise concerns for patient safety, observation practices, and dosing strategies.
A new University of Michigan-led research has identified a connection between keratin 16 and type 1 interferon in the molecular pathways of pachyonychia congenita. The study found that losing or altering K16 causes amplification of the inflammatory response, but also helps pump the brakes on that response.
Research in Malawi finds that attempts to combat child marriage often neglect local perspectives and cultural norms, leading to challenges in implementing effective solutions. The study proposes an African feminist lens to address the issue, considering relationality, community, and cultural embeddedness to understand the problem.
The Pennington Generation study aims to explore the impact of physical activity, nutrition, and sleep on children's health and growth. The study will examine how these behaviors relate to weight gain and obesity over time.
Researchers analyzed brain interactions to explain attention, decision-making, and memory. Models with competitive interactions outperform cooperative ones, enabling flexible activation of regions and intelligent behavior. This breakthrough brings us closer to creating realistic digital twins of the human brain for personalized medicine.
Researchers have discovered a smaller CRISPR enzyme, Al3Cas12f, that can efficiently edit genes in human cells. The enzyme's unique structure allows it to form a stable connection with DNA, making it a promising candidate for therapeutic genome editing.
New research suggests that AI-powered price discrimination could lead to hidden, personalised pricing that consumers cannot see or understand, potentially reducing trust and affecting behavior. Regulators are now facing pressure to decide whether such practices cross the line under EU competition law.
A Drexel University study found that teens are concerned about their attachment to AI chatbots, using them for emotional support and entertainment. The study suggests that these interactions can evolve into addiction-like behavior, affecting their lives offline.
A University of Oklahoma researcher is leading a global water modeling project to create advanced tools and datasets for managing fresh water sustainably. The Re-Analysis of Water for Society (RAWS) project aims to shed light on how humans can best manage fresh water for long-term sustainability.
Dr. Ariel Green will receive the award for her work on deprescribing research, focusing on optimizing medication use for older adults with multiple chronic conditions. She has garnered several grants as Principal Investigator and serves as Chair of the AGS Clinical Practice Committee.
A recent study compared food web similarity in 127 protected areas across Africa, finding that fragmented habitats predict similar food webs. The research also showed that primary productivity is a key factor in determining food web structure.
A new imaging strategy combines dissolvable microneedles with a methylene blue-based nanoparticle tracer to produce clearer images of lymphatic vessels and nodes. The system also reveals segmental contractions linked to lymphatic pumping, opening a path toward more refined visualization and functional assessment.
A living reef coastal defense system has been shown to significantly reduce wave power, supporting reef growth and stabilizing shorelines. The hybrid structure combines engineering and natural processes, offering a potential alternative to traditional engineered structures.
Research from the University of Kansas reveals that chronic pain is linked to higher rates of smoking and vaping, particularly among those with more severe pain. The study's findings highlight the need for targeted interventions addressing both chronic pain and tobacco use.
Researchers from Aalto University developed an AI model that simulates human motion from touchscreen logs, providing insights into physically effortful smartphone interactions. The model helps designers create user-friendly interfaces and identifies areas requiring additional effort.
St. Olaf researchers create mechanical computers that can perform simple computations without a computer chip or power source, harnessing their power from physical force. The devices demonstrate proof of design for alternative computing in harsh settings, paving the way for smart materials and responsive artificial limbs.
A specific protein complex regulates protein balance in plants, influencing their response to environmental stress. Researchers discovered that this process, known as N-terminal acetylation, maintains the stability of the plant proteome by controlling protein degradation and recycling.
A new IIASA-led study offers a practical approach to evaluate the distributional implications of climate action, enabling policymakers to assess justice impacts of emissions pathways. The study found that many existing mitigation scenarios are consistent with justice principles, while few explore limits on energy or meat consumption.
A clinical trial aims to evaluate whether laser therapy reduces vaginal dryness caused by breast cancer treatment. The study, REVITALIZE, plans to enroll approximately 250 women with a history of breast cancer who experience moderate to severe vaginal dryness.
Researchers developed an inhaled treatment to reduce lung inflammation and fluid build-up after severe infections. The therapy targets Angiopoietin-like protein 4 (ANGPTL4) and showed promise in preclinical studies.
Oncology services are often excluded from emergency health priorities, resulting in delayed diagnosis and treatment interruptions. Vulnerable populations, including women and children, face advanced disease stages due to delays in care.
Researchers propose a novel THz metasurface-enabled platform for integrated sensing and imaging, overcoming limitations of slow sequential data acquisition. The system achieves 100% binary image reconstruction with nanosecond-scale accuracy, enabling real-time applications in security, semiconductor, and pharmaceutical sectors.
Super-enhancers are densely clustered regions driving oncogene expression in cancer. Targeting BRD4, CDK7, and SE structure with small molecules and CRISPR may offer therapeutic benefits. Combination therapies aim to overcome resistance and improve outcomes.
Researchers at the University of Groningen discovered that protein clustering in cells leads to reduced movement and improved efficiency in amino acid production. This finding has practical implications for designing efficient cell factories and increasing substance production inside cells.
Researchers at VIB–VUB Center for Structural Biology have discovered a counterintuitive principle for designing membrane proteins. Introducing 'imperfections' or negative design enables synthetic membrane proteins to fold and assemble efficiently. This approach can improve the stability of final folded structures without compromising it.
Researchers have developed a method to extract bio-oil from date palm surface fibers, an abundant biomass resource. The study found that the resulting bio-oil consists primarily of aliphatics and aromatics, making it suitable for targeted recovery and bioenergy applications.
A novel machine learning framework integrates high-resolution remote sensing and dynamic climate windows to estimate early-season winter wheat sowing dates. The framework achieved an R² of 0.82 with most estimates within ±5 days of observed values, capturing regional patterns and fine-scale variations.
Researchers used a cabled marine observatory to study plankton abundance and variety over a four-year period. They found that long-term changes in aggregate abundance and plankton diversity were not influenced by ocean turbulence.
The COLIBRE simulations successfully reproduce real galaxies in the present-day universe and early universe as seen by the James Webb Space Telescope. The models include cold gas and cosmic dust, which strongly affect galaxy appearance in telescopes.
Acute liver failure is driven by massive hepatic necrosis, a catastrophic form of liver injury characterized by extensive hepatocyte loss. Liver progenitor cells play a key role in regeneration and functional compensation, enabling patients to survive despite severe liver damage.
Researchers at KIT have developed the NECOC process to convert CO2 emissions into a solid raw material, which can be used in various industries. The process aims to close carbon cycles on-site at industrial plants, reducing greenhouse gas emissions.
The Hong Kong University of Science and Technology (HKUST) has developed the world's first bio-inspired artificial cilia system capable of replicating natural cilia's complex motion. The system uses a 3D-printed hydrogel microactuator with rapid ion transport, enabling fast and precise movement.
Researchers found that squalene-based adjuvants activate distinct pathways for vaccine protection and reactogenicity, including the role of IL-1β in enhancing efficacy and IL-1α in triggering local swelling. The study's findings could lead to safer vaccine design by targeting specific immune mechanisms.
Researchers at the University of Lausanne uncover a breakthrough in understanding Mount Etna's origin, suggesting that the volcano may have formed through a mechanism similar to petit-spot submarine volcanoes. This discovery opens up new perspectives for understanding how other volcanic systems may form around the world.
Climate change is altering insect emergence timing worldwide, impacting their ability to find food and survive. A study found that insects from cooler regions are particularly vulnerable to warm springs, losing energy quickly and facing poorer starting conditions.
The center offers state-of-the-art facilities for practical skills acquisition, digital technologies integration, and innovation in medical procedures. Future physicians will benefit from cadaver training, real-time imaging, and collaborative research opportunities.
A team led by Professor Julia Beatty explores how feline tumour viruses offer vital insights into human oncology and viral carcinogenesis. Domestic cat hepatitis B virus is strongly associated with feline HCC, mirroring human HBV oncogenic patterns.
A study published in Chinese Medical Journal reveals how mitochondrial activity is regulated in heart muscle cells. Mitochondrial dysfunction disrupts energy production and affects cardiac outcomes, with various proteins managing mitochondrial biogenesis and mitophagy.
A new study from the University of Oxford found that long-term childhood poverty increased sharply among children born after 2013 due to austerity reforms. Nearly one in five children born after this period experience poverty for at least half of their childhood, with severe consequences on education, employment, earnings, and health.
Researchers at Tohoku University have made significant progress in precise nanoscale construction of g-C₃N₄ catalysts, which enables efficient photocatalytic H₂O₂ evolution. The study highlights the importance of nanoarchitectonics in scaling up industrial production.
Researchers have developed a novel sh2isu1 sweet maize germplasm using CRISPR/Cas9 cytosine base editor, offering multiple advantages. The approach enables the rapid generation of desired phenotypes without transgenic components within 1-2 years.
Researchers developed a natural, biodegradable wash that removed up to 96% of pesticide residue from fruit and slowed browning and moisture loss. The coating also showed antimicrobial effects and added nutritional value.
Researchers at the University of Würzburg have directly measured the 'waiting time' in a two-dimensional material, which lasts exactly 24 billionths of a second. This knowledge increases the accuracy of atomic sensors and paves the way for future medical diagnostics.
Researchers have developed a water-soluble cellulose ethyl phosphite (CEP) adhesive that integrates high bonding strength, environmental tolerance, and recyclability. The CEP adhesive demonstrates remarkable thermal stability and resistance to moisture-related degradation, making it suitable for various applications.
PhytoCell, an ensemble learning framework, analyzes plant single-cell RNA sequencing data to identify marker genes and assign cell types accurately. The framework achieves precise annotation of cell subpopulations and effectively removes redundant noise.
Entomologist Mark Moffett observes harvester ants congregating with smaller cone ants in Arizona's Chiricahua Mountains. The unusual behavior involves the cone ants licking and nibbling the harvester ants' body surfaces, possibly consuming calorie-rich dust-size morsels.
The new guidance provides practical routes forward for AI use in every publishing role, promoting accountability, transparency, risk-awareness, and innovation. It introduces structured checkpoints and ready-to-use tools to make responsible AI use practical, not theoretical.
Current large language models struggle with early diagnostic reasoning and cannot be relied upon for patient-facing clinical decisions. The study highlights the need for further improvement in these areas to enhance patient care.
A new USC study found that in-store pharmacies filled less than 2% of mifepristone prescriptions since the FDA eased dispensing requirements, with mail-order pharmacies accounting for most fills. The study suggests significant access gaps in states with stronger legal protections for abortion.
A new study found that school-age children and adolescents with medically diagnosed traumatic brain injury (TBI) have higher rates of anxiety/depression. Family resilience was associated with decreased odds of depression after TBI, suggesting a crucial role in recovery.