A study reveals that a cellular interaction between immune cells and fibroblasts drives the progression of Sjögren's disease by promoting chronic inflammation. The CD153+ CD4+ T cell-CD30+ fibroblast axis is identified as a key trigger, and targeting this axis may provide new therapeutic opportunities.
Scientists at the Simons Foundation's Flatiron Institute developed a new method that enables faster simulations of molecular behavior without sacrificing accuracy. The breakthrough could significantly reduce time and energy demands for simulations, impacting fields such as material design and drug interactions.
Researchers found that even morphologically similar pollinators can differ markedly in the diversity and heterospecificity of pollen they transport. This variation has important implications for understanding how different pollinators influence plant reproduction and evolution.
A newly developed open-source tool called Talos is highly effective at detecting new rare disease diagnoses. The tool automates the reanalysis process of stored DNA data, integrating monthly updates of new knowledge about genes and variants to identify potential new diagnoses.
Scientists discovered a natural microbial compound that protects the gut and supports future treatments for inflammatory bowel disease. UroA activates a protective pathway in intestinal epithelial cells, triggering the release of molecules associated with maintaining normal intestinal function and repairing the gut lining.
A recent study found that people with active TB have a specific inflammatory response in their airways, dominated by neutrophils that can lead to disease progression. In contrast, those who control the infection have a different immune cell balance, suggesting a way to predict and prevent TB through early intervention.
A new study finds that Alzheimer's disease and related dementias will cost the US $818 billion this year, driven by costs associated with care and loss of productivity. The study's comprehensive model accounts for often-overlooked factors like diminished quality of life and unpaid care provided by family members.
The AACR Cancer Disparities Progress Report 2026 highlights the progress being made against cancer disparities while also raising awareness of the disproportionate toll that cancer continues to exact on certain populations. The report calls for continued federal support for cancer disparities research to ensure that advances against ca...
Researchers at CNIC developed a technique to analyze proteins in individual cardiomyocytes, uncovering new clues about cardiac regeneration. The study found that the transcription factor Myc alters protein expression differently in each cell, generating regenerative potential in a subpopulation of cardiomyocytes.
Researchers developed a unified theoretical framework for ultrasound wave propagation and energy dissipation in porous rock formations. The study identifies three distinct longitudinal-wave types with different physical origins, providing a basis for understanding and predicting ultrasonic wave behavior in multiphase porous media.
A team of researchers has reported a generalized Doppler effect that enables simultaneous capture of rotation magnitude and direction with high accuracy. The approach uses spin-orbit coupling to encode motion information into multiple degrees of freedom, resulting in substantially larger frequency shifts than conventional methods.
Oral squamous cell carcinoma (OSCC) is associated with significant morbidity and mortality due to tumor recurrence, metastasis, and therapeutic resistance. TP53 mutations are strongly linked to advanced tumor stage, lymph node metastasis, therapy resistance, and poor prognosis.
Janus 2D materials' synthesis has been solved by uncovering the underlying physics, paving the way for more precise manufacturing of electronics and clean energy technologies. The 'Electron Accumulation Model' controls the reaction at room temperature, accelerating it with ultraviolet light.
Researchers found that intestinal mucus provides a niche for Klebsiella pneumoniae colonization and supports bacterial growth. Mucus exposure also increases sensitivity to certain antibiotics, suggesting a new target for improving therapy.
The National Herbarium of Ukraine is a global archive of biodiversity containing over 2.3 million plant specimens, including priceless material gathered by renowned botanical explorers. Digitisation and international collaboration are crucial to preserving this irreplaceable scientific resource.
Research compares three hemp fiber preparation methods, finding TEMPO-oxidized nanocellulose ideal for high-stability applications and hydrolysed SCNC suitable for composites and packaging. The study demonstrates sustainable production of high-performance bio-based materials from abundant agricultural resources.
Human fetal tissue research in Japan faces challenges related to burden on women undergoing induced abortion and male partner involvement. The study highlights the need for adapted governance frameworks that balance internationally shared standards with national legal systems and social contexts.
A new study highlights the dual threat of extreme humid heat and catastrophic rainfall during the Indian monsoon, while also revealing a powerful new tool to predict the monsoon up to two years in advance. The research paints a sobering picture of climate change's impact on the region.
A new review compares conventional and microwave-assisted pyrolysis, showing how microwave heating can tailor biochar for removing metals, dyes, pharmaceuticals, and microplastics. Microwave-derived biochars often show higher surface area, stronger mesoporosity, and greater retention of oxygen-containing functional groups.
A new study uses biochar-doped hydrogel to turn sunlight into vapor more efficiently, improving water transport and reducing heat loss. The hybrid material achieved a surface temperature of 41.1 °C and an evaporation rate 1.87 times higher than that of the control hydrogel.
Researchers from Curtin University and the Geological Survey of Western Australia have precisely dated the oldest known asteroid impact on Earth to around 3 billion years ago. This discovery pushes the Earth's impact record deeper into geological time, offering a rare glimpse of the violent processes that shaped the early Earth.
A new study by UCL researchers found that mothers with care proceedings in England are 21 times more likely to die within 10 years compared to other mothers. The study analyzed data from NHS hospitals and family court records, revealing a starkly higher risk of maternal mortality among mothers who experienced care proceedings.
Researchers have developed a novel treatment technique using sugar-coated nanoparticles to target and destroy glioblastoma cells. The method overcomes two major obstacles in glioblastoma treatment: delivering therapeutic agents through the blood-brain barrier and targeting tumors preferentially.
The UN has launched an initiative calling on AI companies to publicly disclose their environmental impacts, including carbon, water and land footprint. The move comes after a report highlighted the massive electricity demand and environmental impacts of AI systems.
Researchers developed a wearable, enzyme-free glucose monitor built from glucose-responsive hydrogel microneedles, which can sustain stable glucose sensing for up to 56 days. The ARMPatch uses conventional ultrasound imaging and has been shown to be strongly correlated with commercial glucometers in animal models.
A new study reveals that species with larger brains produce fewer but larger offspring, leading to the evolution of larger eggs. The research analyzed data from mammals, birds, and reptiles, suggesting that brain evolution drove changes in reproduction across dinosaurs and birds.
A new wearable monitoring system called OMEGA aims to replace outdated fetal heart rate monitoring technology with a unified real-time assessment of fetal oxygen delivery and adaptive capacity. The system could potentially reduce C-section rates and improve maternal and fetal health outcomes, saving millions in healthcare costs.
Researchers identified a severe outbreak of bivalve transmissible cancer in soft-shell clams in Puget Sound, with prevalence exceeding 75% by 2024. The disease was recently introduced from Atlantic Coast populations and was tracked using a new environmental DNA assay.
Researchers captured cultural evolution of new dialects in sperm whales living in eastern Mediterranean. Whales developed a new form of vocal dialect used by western basin animals, showing progressive occupation from west to east.
A large long-term study found that children who consume sugar-sweetened beverages and fruit juice have a higher risk of hypertension later in life. Replacing these beverages with whole fruits or water was associated with lower risk of hypertension.
New research reveals that many 'green' claims are difficult to verify, often masking the full truth. Consumers may pick up products thinking they're doing the right thing, but the label only refers to one part of the product's journey.
Researchers found that both free water and bound water slowed the intensity of pyrolysis reactions and increased biochar yield. A biomass water content of around 30% may offer a practical balance for pyrolysis, balancing biochar yield and energy demand.
A breakthrough study reveals that powerful solar storms can lead to sharp changes in North American weather patterns, including declines in precipitation. The more intense the storm, the more dramatic the shift in weather.
An analysis of family court proceedings found that first-time mothers who faced care proceedings were 21 times more likely to die within 10 years. Most of these deaths (73%) were preventable and related to suicide, homicide, drugs/alcohol, or unintentional injury.
A research group developed an edible agent capable of social interaction to explore human-food interactions and psychological acceptance. Participants perceived different behaviors as affecting mind perception and reluctance to eat or guilt, indicating a need for further studies.
The partnership aims to leverage SDSU's technology transfer expertise to commercialize innovations from San Diego Zoo Wildlife Alliance's research, conservation, and wildlife care initiatives. This collaboration will help translate scientific breakthroughs into real-world solutions for society and wildlife populations.
A new study has identified biological pathways that explain why air pollution affects some people with asthma more than others. Researchers found that individuals with specific genetic variants are more susceptible to the harmful effects of fine particulate matter, and that targeted interventions may be able to blunt these effects.
A large study found that hourly movement breaks of just 5 minutes each are the most effective balance between feasibility and effectiveness in mitigating sedentary harms. The breaks significantly improved mood and reduced fatigue, with no impact on work performance.
A systematic review and meta-analysis found no strong evidence that most IVF add-ons improve fertility. However, weak evidence suggests benefits from EmbryoGlue, endometrial scratching, and physiological intracytoplasmic sperm injection. The study aimed to provide evidence-based information for patients making decisions about IVF add-ons.
Researchers at KAIST developed DiSPo, a robot AI model that can flexibly improve task precision from coarse demonstrations, enabling robots to perform sophisticated tasks with high accuracy. The technology achieved significant improvements over existing models in simulation and real-world experiments.
The Seismological Society of America's new journal, The Seismic Record, has achieved an exceptional impact factor of 5.3, ranking 6th globally. Its gold open-access model has expanded its international audience, with over 485,000 downloads to date.
A recent study found that maternal obesity and excessive pregnancy weight gain significantly increased the risk of childhood obesity by age 3. Researchers tracked nearly 3,000 mother-child pairs and discovered that excess pregnancy weight gain was common, affecting about four in 10 mothers.
A new paradigm for brain-computer interfaces uses text sequence stimulation to evoke robust brain responses while being gentler on the eyes. The technology achieved high-speed operation with low discomfort, outperforming conventional brightness flicker in comfort and preference across a wide frequency range.
Alex Botts, a technical account manager at Oak Ridge National Laboratory, received the 2026 Young Energy Professional of the Year Award for her leadership in industrial energy efficiency. She supports DOE's Better Plants Program, helping industrial partners identify and implement energy-saving opportunities.
The editorial highlights the persistent gap between policy and action on physical activity, despite decades of evidence and well-developed frameworks. The authors propose an independent Global Alliance for the Promotion of Physical Activity to bridge this gap through capacity-building and measurable implementation outcomes.
A new blood test, Stockholm3, detected significantly more aggressive prostate cancers than the PSA test without increasing unnecessary follow-ups. The study shows that Stockholm3 identifies 90% of aggressive cancer cases, compared to 74% for PSA.
A Michigan State University team discovered that two closely-related proteins STAG1 and STAG2 play distinct roles during antibody-gene assembly. STAG2 acts as a molecular gatekeeper, preventing oversized DNA loops, while STAG1 promotes long-range DNA interactions needed for assembling antibody genes.
Researchers seek to understand the biological mechanisms behind Ewing sarcoma's rapid growth and spread, developing new tools to visualize DNA structures and regulate gene expression. This could lead to personalized cancer treatments targeting specific molecules for improved patient outcomes.
A study by Dr. Juliane Bräuer and her team discovered striking similarities in dog-human interactions worldwide. Across five culturally diverse regions, dogs consistently demonstrated active communication with their owners and relied heavily on them for guidance in difficult situations.
Researchers analyzed historical records and archaeological sites to discover moose were part of southern Rocky Mountain ecosystems long before modern reintroductions. They found evidence of moose being well-known and deeply integrated into traditional knowledge of Native people in the region.
Researchers developed a non-contact optical sensing strategy to detect ethanol molecules in air using light-field distortions and deep learning. The system employs a graphene-based Fresnel lens to focus light through interference, capturing minute changes in the focal spot formed by the lens.
A new study by UT Arlington's Research Enhancement Program investigates how technology is used to control and monitor victims of intimate partner violence. The research team aims to identify warning signs and develop strategies to protect survivors from digital abuse.
A new study found that job dissatisfaction was the leading reason for nurse turnover, with 2.6 times more likelihood to leave among unhappy nurses. Education also played a role, as current students and those with graduate degrees were more likely to leave their jobs.
Researchers will analyze unique lunar samples, deep-sea sediments, and geological archives to detect rare radionuclides and shed light on nearby cosmic events. The project aims to reveal the history of our cosmic neighborhood and its possible influence on Earth's evolution.
Two UCD research projects, REVOLVER and PanAsia, have secured funding of €2.5 million each under the ERC Advanced Grant programme. The projects will explore the potential of RNA molecules in medicine and investigate the cultural networks that shaped Southeast Asia's decolonisation.
MIT researchers developed a new system-on-a-chip called Gleanmer, which generates highly accurate 3D maps of the robot's environment using Gaussians to represent obstacles. This approach reduces memory and power consumption by up to 99%, making it suitable for lightweight augmented reality headsets.
A study found that sleep deprivation leads to increased markers of brain cell connections, including synaptic vesicle glycoprotein 2A (SV2A), in areas such as the hippocampus. This suggests that sleep plays a crucial role in restoring cellular balance and may be important for maintaining neural health.
The University of Liverpool has been awarded €8.5M from the European Research Council for three innovative five-year projects. The PhysiQuake project will investigate physics and chemistry processes during earthquakes, while MaterED aims to develop a hypothesis-driven approach to discovering functional materials.
Researchers have identified immune markers that can help doctors determine which breast cancer patients are unlikely to benefit from chemotherapy. The new AI-based method analyzes the body's own immune cells found near a tumor, providing additional insight to identify patients who can safely have chemotherapy withheld.
Researchers developed a method combining AI and mathematical models to accelerate MRI scans for breast cancer imaging, achieving improved tumor visibility and high diagnostic sensitivity. The ELITE method has the potential to improve not only MRI scans but also other imaging platforms.