A Rutgers Health study found that perceived effectiveness of semaglutide, such as noticeable weight loss or reduced food cravings, was the strongest predictor of satisfaction and intention to continue treatment. Although gastrointestinal issues like nausea and vomiting were common, they didn't significantly influence satisfaction score...
Researchers have identified three unique subtypes of mismatch repair deficient high-grade gliomas, providing a clearer understanding of their development and behavior. The findings are helping guide more precise therapies and offer hope for a potential vaccine to target cancer cells earlier.
University of California San Diego scientists have solved how the circadian clocks within microscopic bacteria precisely control gene expression during the 24-hour cycle. The researchers identified six proteins needed to rebuild this clock, generating a simplified cyanobacterial system with a clock that only needs.
Researchers develop calcium hydroxide modified biochar from discarded Camellia oleifera shells to remove ammonium and phosphate from water, showcasing strong adsorption performance. The material demonstrates potential for practical agricultural and industrial wastewater treatment, maintaining strong performance in real-world tests.
A recent study published in the American Journal of Human Genetics has established a connection between the ASTN1 gene and undiagnosed human neurodevelopmental disorders. Researchers found that loss-of-function variants of the gene cause a range of developmental delays, intellectual disabilities, autism, ADHD, and epilepsy in children.
Researchers introduced transfer learning into muon tomography to address data limitations and improve material identification. The approach achieved high prediction accuracy, especially when combined with physics-guided sampling.
Researchers conducted semi-structured interviews with 17 participants to understand parent experiences with in-home medical devices. The study highlights the critical role of device user experience in designing medical devices for children with complex medical needs.
New analysis by Queen Mary University of London warns UK's reliance on EVs and heat pumps may offer little benefit in reducing emissions. The study urges urgent focus on grid capacity, renewables, and carbon capture to achieve net-zero targets.
Researchers have developed high-density 1D ionic wire arrays that achieve simultaneous high selectivity and conductivity in ion-exchange membranes. The optimized membrane delivers ultrahigh power density of 40.5 W m-2 under a 500-fold salinity gradient.
A recent NSF grant will support the development of new diagnostics and predictive models for understanding self-competition and weak asymmetry in turbulent flows. The project aims to uncover hidden patterns that current models miss, leading to improved simulations in weather forecasting, climate modeling, and engineering design.
Scientists have developed a novel computational framework for real-time, personalized heart rate variability monitoring. The framework provides robust, adaptive alerts and improves the accuracy of HRV analysis by excluding artifact-prone periods.
A study found that AI-generated messages about public policies are highly persuasive, influencing policy views by an average of 9.74 percentage points. The study's results suggest that authorship labels have no significant impact on the persuasiveness of AI-generated content.
A new report published in The Lancet Child & Adolescent Health highlights the significant global palliative care gap among children, with 96% of those in need living in low- and middle-income countries. The study estimates that $1 million per year is sufficient to cover pain medications for all children ages 0-14 years in need who live...
Researchers at EPFL's Brain Mind Institute have discovered that rejuvenating specific engram neurons can restore memory performance in multiple mouse settings. This approach uses a short pulse of genes to 'reprogram' these cells, bringing their functionality back to levels seen in young mice.
This paper reviews the latest methods for vision-based 3D occupancy prediction in autonomous driving, categorizing them into feature-enhanced, computation-friendly, and label-efficient approaches. The authors propose inspiring future outlooks and provide a regularly updated GitHub repository to collect related papers, datasets, and codes.
Researchers have discovered a key factor involved in pulmonary hypertension: beta arrestin protein. The protein helps guide signaling molecules and is essential for relaxing muscle cells, reducing intracellular calcium concentration.
Dementia Care Aware and the Institute for Healthcare Improvement are collaborating to support the implementation of the 4Ms Framework of an Age-Friendly Health System. This collaboration advances their shared goal of providing evidence-based care for dementia, with DCA bringing expertise in brain health and IHI providing expert faculty...
A new review highlights the need for planned sequential bone therapy to reduce the risk of spontaneous vertebral fractures after denosumab therapy. Denosumab discontinuation can trigger a 'rebound phenomenon' marked by rapid bone turnover, bone loss, and potentially multiple vertebral fractures.
Researchers developed a thermodynamically controlled coordination strategy to modulate magnetic domain configurations, enabling precise regulation of magnetic nanoparticle spacing and resulting in effective low-frequency EM wave absorption. The approach also enhances interfacial electron transport and polarization loss, making the mate...
Researchers used transcranial alternating current stimulation to synchronize frontal and parietal lobes, increasing participants' ability to make altruistic choices. This study provides new insights into the neural basis of social decisions and has implications for future research on cooperation.
Dr. David Gius, a renowned physician-scientist and radiation oncologist, has been appointed as the new director of the University of Cincinnati Cancer Center. He brings a robust research portfolio, including active clinical trials and NIH grants, to enhance regional access to superlative care.
The Endocrine Society has announced its inaugural Rare Endocrine Disease (RED) Fellows Program, designed to improve outcomes for people living with rare endocrine diseases. The program addresses critical gaps in awareness, diagnosis, and care through a partnership with the National Organization for Rare Disorders.
Researchers investigate three types of nature values (intrinsic, relational, instrumental) to understand human-nature relationships and their impact on the health of the Earth. The study found that valuing the relationship between humans and nature is linked to attributing agency to nonhuman beings.
A new study found that nearly one in five adults with tinnitus have had to reduce their working hours or leave employment due to the condition. The research also revealed that targeted interventions, such as cognitive behavioural therapy, can improve work productivity and overall wellbeing.
Researchers demonstrate polarization-based microscopy as a tool for EDS diagnosis, detecting structural signatures in unstained biopsy samples. The study identifies five parameters that can differentiate classical from hypermobile EDS, reflecting variations in collagen organization.
A new study from the Kinsey Institute found that passionate love is relatively infrequent, occurring about twice in a lifetime. The research surveyed 10,036 single adults aged 18 to 99 and found that 14% had never experienced passionate love, while 28% experienced it once.
Researchers developed an adversarially robust streaming algorithm for triangle counting in unweighted graphs, exhibiting strong tracking capabilities. Additionally, a two-pass algorithm was proposed for estimating total triangle weight in weighted graphs, applicable to fully dynamic streams.
A resource redistribution experiment with Hadza adults suggests that egalitarianism is not primarily driven by a desire for equality, but rather by individual self-interest and norms of fairness. The results highlight the importance of extrinsic factors in shaping traditional sharing behaviors among hunter-gatherers.
Scientists discovered a 307-million-year-old fossil of an early land vertebrate that evolved to eat plants, challenging previous assumptions about the origins of herbivory. The 'tyrant digger' had tough teeth on its roof and probably ate smaller animals along with vegetation.
Phyton Biotech has successfully transferred the manufacturing process for Corallopyronin A (CorA), a novel anti-infective agent with potent activity against filarial infections and bacterial infections. The technology transfer marks an important milestone in the Company's specialty GMP fermentation capabilities.
A new study from Queen Mary University of London finds that species turnover in ecosystems has significantly slowed down despite accelerating climate change. This slowdown is attributed to environmental degradation and the depletion of regional life pools, suggesting a loss of momentum in biodiversity.
Researchers identified interferon regulatory factor 7 (IRF7) as a central regulator of smooth muscle cell plasticity in atherosclerosis. This transition accelerates plaque growth and destabilization, offering new insight into the risk of plaque rupture and cardiovascular events.
The partnership aims to develop next-generation mRNA vaccines with enhanced stability and targeted delivery, providing broader protection against emerging pathogens. This collaboration combines Ethris' mRNA technology platforms with DZIF's vaccine research expertise to accelerate the development of variant-ready vaccines.
Researchers developed a blood-based DNA marker called protein epiScores to predict colorectal cancer recurrence and survival. Four markers were linked to increased risks of recurrence and death, with one marker associated with an 80% higher risk of death.
A new study reveals that China's construction sector is a significant driver of premature deaths due to ambient fine particulate matter (PM2.5) exposure. The research estimates that around 1.1 million premature deaths were caused by construction-related emissions in 2019.
A new study examines the economic and social legacies of historical exploitation, arguing that institutional reform, cultural restoration, and fairer international relationships are needed to address ongoing inequalities. The research frames reparations as a tool for long-term structural change, linking historical accountability to cur...
Research reveals that children and adolescents with juvenile fibromyalgia exhibit heightened sensitivity to sounds, bright lights, and multisensory stimulation. This hypersensitivity is closely tied to the disease's severity and brain function, providing new insights into its mechanisms.
Researchers have developed a planar micrometre-scale zinc–air battery that operates in a safe, near-neutral gel electrolyte, delivering high energy and power. The breakthrough enables the integration of onboard power sources into chip-scale systems, enabling fully autonomous micro-devices.
A study found that only planets with medium-level oxygen conditions during core formation can retain essential elements phosphorus and nitrogen, necessary for life. This limits the number of potentially habitable planets, as most solar systems have stars with different chemical compositions.
According to the latest ECDC report, 7,655 measles cases were reported across 30 countries in 2025, with eight fatalities. This represents a significant decrease from 35,000 cases in 2024 but is still almost double the number of cases in 2023.
The North American wild mountain sheep is losing its habitat to industrial mining, human activity, and climate change. The book highlights the risks faced by this species, which nearly collapsed in previous decades but now faces grave risks from disease and habitat loss.
Research evaluates various scaled decentralized system configurations, demonstrating their potential to outperform centralized systems in environmental sustainability. Carefully designed SDSs offer a sustainable pathway for wastewater management in dense cities by integrating treatment and local resource recovery.
Research team led by biologist Joost Woltering discovers how ancient genes from fish midline fins were 'redeployed' to establish the dorsal-ventral axis in human limbs, allowing for complex limb differentiation and adaptation for life on land.
A team of researchers led by Yoshiteru Maeno used magnetic resonance based on muons to investigate the superconducting state of strontium ruthenate. They discovered that the material exhibits spin-singlet superconductivity, which provides crucial insights into the behavior of unconventional superconductors.
Researchers from URV discovered that ultrasound can characterise visceral fat with high accuracy, a determining factor in metabolic risk. The study found a correlation between elevated visceral fat levels and the presence of prediabetes and metabolic syndrome.
Chronic ephedrine exposure disrupts brain development and behavior in adult fish, causing changes in locomotion, anxiety-like responses, and learning performance. Transcriptomic and neurochemical analyses reveal widespread molecular disruptions, including impaired synaptogenesis and neurotransmitter balance.
Research finds that deep-sea organisms can access nutrients from sinking organic particles under intense hydrostatic pressure. This discovery has implications for the global carbon cycle and climate processes.
Researchers found that when pancreatic tumors touch the superior mesenteric vein, patients who undergo surgery first experience reduced survival rates. In contrast, those who receive chemotherapy before surgery have similar survival outcomes to those with non-vein touching tumors. The study suggests reclassifying tumors based on vein i...
CAR T-cell therapy is now available for eligible primary CNS lymphoma patients, thanks to Dana-Farber-led research. The FDA label update removes a prior exclusion and may expand treatment options for relapsed or refractory patients.
A new study found that strength training is the most effective tool for achieving 'high-quality' weight loss, reducing body fat while preserving and even increasing muscle mass. This type of exercise also reduces waist circumference, a key indicator of abdominal obesity and cardiometabolic risk.
A landmark study of nearly 1.2 million infants suggests that a vegan or vegetarian diet does not compromise infant growth by age two. The research found that infants from plant-based households follow growth trajectories nearly identical to their omnivorous peers, providing reassuring evidence for parents and pediatricians.
A team of scientists experimentally demonstrated deterministic entanglement-assisted quantum communication over 20.121 km in fiber channels, outperforming classical communication in metropolitan areas. They proposed an improved continuous-variable dense coding scheme to enhance transmission efficiency and reduce excess noise.
The REST-COAST project has developed a mobile app, My REST-COAST, to raise public awareness and engagement in coastal ecosystem restoration across Europe and Israel. The app provides interactive maps, site-specific biodiversity information, and gamified learning paths to encourage users to explore restoration strategies.
A study by NYU School of Global Public Health found that anxiety about aging contributes to accelerated epigenetic aging, with greater concern about declining health having the strongest association. This can lead to physical decline and increased risk of age-related diseases.
Researchers at KAIST have identified a new principle for catalyst design that allows ceria to selectively use different oxygen sources depending on the reaction environment. By adjusting the size of the catalyst, it can choose whether to use oxygen from the air or store it internally.
A recent study found that China's water-supply carbon emissions rose to 228 Mt CO2 by 2022 due to increased reliance on energy-intensive water sources. The research emphasizes the need for low-carbon alternatives and integrated governance to address the water-energy-carbon nexus.
The IPK research team developed a prediction model using large datasets, genomic markers, and environmental information to forecast wheat yield in specific locations. The model achieved improvements of up to 23% in predicting new hybrid performance, similar to getting a tailored suit that fits the environment.
Researchers propose a multi-channel TDC with Physically Unclonable Function (PUF) to generate unique fingerprints of ICs. This approach addresses security concerns in programmable devices and offers improved performance and lower cost.
A major study has shown that tumour stage at diagnosis is strongly linked to childhood cancer survival across six different cancers. Researchers analysed data from 9,883 children in 27 countries and found significant variation in three-year survival rates between regions, particularly in the UK and Ireland.
A new study found a combination of genetic, environmental, microbial and social factors influence childhood food allergies. Early-life factors like skin health, microbiome, and environmental exposures increase the risk of developing a food allergy by age six.