A study by Nikolai Kunitsõn shows that participatory theatre can bridge the gap between Estonian- and Russian-speaking young people's civic skills. The method, called forum theatre, allows young people to practice debating, resolving differences of opinion, and taking a stand in a playful way.
A study found that secukinumab significantly improved skin scores in moderate-to-severe plaque psoriasis patients with subclinical enthesitis, reducing inflammation before irreversible damage occurs. Ultrasound revealed marked thinning at enthesial sites, particularly the right Achilles tendon.
Researchers propose protein coronas as a dynamic navigation interface to shape how nanomedicines are recognized and delivered across the blood-brain barrier. The corona can be manipulated to bias circulation, targeting ligands, and intracellular trafficking for improved brain delivery.
Researchers at Penn State and NIST developed a new way to build tinier, smarter glass sensors filled with highly precise and stable atoms. These sensors can measure high-frequency electromagnetic signals, including millimeter-wave radiation, and offer improved navigation accuracy and reliability.
A new AI framework reduces operational costs by 6% and improves grid reliability through coordinated energy source management. The approach uses distributed reinforcement learning to optimize hydrogen storage and minimize coal consumption.
Researchers developed genetically engineered CAR T cells specifically targeting bladder cancer cells and delivered them directly to the bladder via a catheter. This approach shows promise in controlling bladder tumors in mice and may be effective in humans, offering an alternative to life-altering procedures like bladder removal.
Researchers found that long-term improvements in water quality, as well as increased occurrence of certain aquatic species, are associated with broad environmental regulations. Conservation policies have helped restore freshwater ecosystems and prevent extreme species loss, indicating the importance of protecting biodiversity and human...
This study explored the association between mental health, dermatology-related quality of life, and probiotic intake in 305 Brazilian adults. Women showed higher anxiety, depression, and stress scores compared to men, with strong positive correlations among these conditions.
A new study analyzing over 11,000 YouTube videos and comments found that online discussions surrounding avian influenza transformed scientific information into broader debates involving institutional trust, politics, and alternative interpretations of disease risk. The analysis identified dominant themes, emotional patterns, and shifts...
Skin, a new international dermatology journal, has launched in Beijing to provide a high-quality platform for Chinese researchers to publish original studies on skin and venereology. The journal will adhere to rigorous academic standards and prioritize rapid global dissemination.
Researchers from the German Primate Center replicate historical findings by Renate Schweizer on brain convolutions, confirming a connection between deep-lying winding and 'bridge.' The study analyzed structural MRI scans of healthy adults, finding a higher prevalence of 'bridge' in twins.
A new study from Cornell University finds that warmer temperatures and drier air slow forest growth, reducing the land's capacity for carbon storage. This discrepancy could accelerate warming and its impacts, as climate models may overestimate forests' future potential for carbon storage.
Researchers at Max Planck Institute develop technique to interrogate molecules on surfaces with spectroscopic precision, reaching the ultimate quantum limit. This breakthrough enables study of molecule-surface interactions and molecular quantum technologies.
A cross-sectional study found significant increases in glucagon-like peptide-1 (GLP-1) per-patient days supplied in employer plans from 2021 to 2024, driven by higher growth in weight loss coverage. This could signal a growing financial burden on patients and payers as drug costs increase over time.
Researchers at University of California San Diego have developed a large-scale screening approach that identifies proteins controlling alternative polyadenylation (APA), a fundamental step in gene expression. The study reveals 63 high-confidence activators of poly(A) site usage, including seven new regulators previously unknown.
Scientists have created a method to apply graphene to metal surfaces using microwave plasmas, showing promise in protecting against corrosion. The technique involves two methods: direct transfer and three-step process, with the latter achieving better results in surface coverage.
Researchers found that 77% of rocks analyzed cooled at roughly the same time between 5-7 million years ago, providing direct evidence for a massive uplift event. This timing coincides with a previously known event during which the Pacific plate rotated, causing widespread deformation and uplift along the Ring of Fire.
Steroid-induced rosacea (SIR) and steroid-induced rosacea-like dermatitis (SIRD) require different management approaches due to distinct pathologies. SIRD is a curable condition with intense itching, dryness, and scaling, while SIR presents lifelong episodic flushing and redness.
Researchers directly visualized a rare type of chemical bond between heavy elements, providing evidence of electron sharing and resolving debate about how electrons are shared in these systems. The study validates theoretical models and enables more routine experimental study of electron sharing.
The V-FOREST project aims to develop mobile and decentralized processing pathways for damaged forest biomass, producing bio-based cosmetic ingredients. The consortium will combine pretreatment, fractionation, and chemical/biological conversion routes to create scalable solutions with real societal impact.
A nationwide Japanese study of over 82,000 children found that exclusive breastfeeding for six months significantly reduces the risk of short sleep duration at one year of age. The study also suggests that breast milk's adaptability to infant needs and its melatonin content help regulate healthy sleep rhythms.
Researchers at ORNL developed JACC to advance performance portability for Julia across heterogeneous HPC architectures. The framework enables a single codebase to execute efficiently on CPUs and GPUs from multiple vendors, reducing software barriers.
A 24-year-old woman presented with unexplained darkening of her hands, feet, gums, and tongue, later diagnosed with rare Addison's disease. After treatment, her symptoms resolved completely, highlighting the vital role of dermatologists in recognizing systemic diseases through skin manifestations.
A study published in Science Advances reveals that Earth's ionosphere contributed to the majority of ring current ions during a record-breaking super geomagnetic storm in May 2024. This finding highlights the importance of understanding how much Earth's ionosphere contributes to the ring current, as it may be essential for accurately p...
Researchers suggest using AI to strengthen ransomware defense by integrating synthetic data generation and behavioral forecasting. AI can detect new malicious attacks and classify unknown attack methods, helping to build trust among users.
Insilico Medicine announced a record-breaking $2.5 billion global R&D collaboration with SK Biopharmaceuticals, focusing on neuroimmune disorders. The company showcased its proprietary Pharma.AI platform and demonstrated its expertise in accelerating drug discovery.
SpongeBoost is organizing an online webinar to explore how project outputs can inform action for sponge landscapes. Participants will hear from experts on specific results and engage in interactive discussions.
Researchers evaluated two somatostatin receptor PET tracers for breast cancer treatment, found SSTR-positive tumors in many estrogen receptor-positive cases. A new PET tracer showed promise for detecting Staph infections, while an interim PET scan may help track response to PSMA therapy in advanced prostate cancer.
Researchers have created a single-dose DNA method that produces weight loss and blood glucose control in murine models lasting up to 10 times longer than current therapies. The approach delivers instructions to cells to produce long-acting incretin hormones, eliminating the need for repeated dosing.
The rise of AI-generated content threatens authenticity in the clinical landscape, from AI chatbot impersonations to deepfakes of real physicians. Existing laws and regulations are struggling to keep pace with these emerging challenges.
A new study from the University of Bergen shows an association between breastfeeding up to six months of age and a reduced risk of ADHD symptoms. Exclusive breastfeeding during this period appears to offer the strongest protective effect, with clear but moderate benefits observed even after adjusting for genetic risk factors.
Researchers at Utrecht University discovered that introducing multiple opportunities for cooperation in animals can change social dynamics and partner preferences. This challenges previous studies using single-location setups, suggesting a need to reconsider animal behavior experiments.
A study from the University of Gothenburg found that patients with chronic pain do not have equal access to specialized rehabilitation programs. Sociodemographic factors such as education, age, sex, and region of birth play a significant role in determining participation rates. The study suggests that addressing these disparities is cr...
Researchers are developing a new gene therapy to treat CTLA-4 insufficiency, a life-limiting inherited immune disorder. The treatment involves replacing a faulty gene in a patient's own immune cells using CRISPR/Cas9 technology.
A new study identifies CsYP as a key regulator of cucumber peel color by shaping chloroplast development and pigment accumulation. The findings show that disruption of CsYP damages chloroplast structure, reducing chlorophyll and carotenoid levels and producing yellow fruit peel.
The platform enables simultaneous visualization of multiple hepatic cell populations, including hepatocytes, cholangiocytes, macrophages, endothelial cells and hepatic stellate cells. It also extends multiplex imaging beyond tissue sections to organoids, primary liver cell cultures and advanced liver-on-a-chip platforms.
Hanyang University researchers developed AI-guided microneedle patches that actively change shape at physiological temperature to help close wounds while delivering regenerative therapy and antibacterial protection. The platform accelerates wound closure and improves tissue regeneration compared with conventional approaches.
Researchers found that CAR3 coordinates bone formation and regeneration by forming a molecular complex with collagen type I alpha 1 and recruiting bone sialoprotein. The study identified CAR3 as a previously unrecognized regulator of osteoblast differentiation, highlighting its potential for treating bone disorders.
A multi-omics study identifies the TNF-α/IL-1β/PGE₂ axis as a driver of mucus overproduction and colonic lesion formation in Cronkhite–Canada syndrome. The study reveals extensive epithelial remodeling, goblet cell hyperplasia, and an inflammatory colonic epithelial cell subset characterized by high expression of lipocalin-2.
Digital twins are expanding rapidly, using real-time data to simulate and analyze systems before applying them in the real world. The study emphasizes the need for interoperable architectures, machine-readable metadata, and standardized trust frameworks to address challenges such as privacy, cybersecurity, and uncertainty.
Researchers have introduced laser reflective tomography to overcome the speed-resolution trade-off in NLOS imaging, achieving kilometer-scale high-resolution imaging without scanning mechanisms. This innovative approach combines single-point detection with multi-angle projection data for accurate scene reconstruction.
Researchers found that ROS-producing enzymes coordinate cell proliferation, tissue integrity, and differentiation in plants. The study used a liverwort model to examine the role of RBOHs in plant development, revealing their importance in maintaining normal cell shape and tissue organization.
A new study reveals that China's environmental restoration efforts have reversed freshwater deoxygenation through effective wastewater management. By reducing organic pollution and increasing dissolved oxygen concentrations, the country has seen a dramatic reduction in hypoxic events.
Scientists have discovered that fungi and bacteria can work together by managing copper in their shared environment, forming larger and more active biofilms. A finely balanced copper environment is crucial for the cooperation between the two species, making it a potential target for new infection treatments.
Stanford researcher Ellen Kuhl's AI tool, BurgerAI, creates novel burger recipes optimized for deliciousness, sustainability and nutrition. The burgers were tested in a blinded taste test and found to be comparable to popular fast-food options.
A large clinical trial found that an AI support tool improved the quality of clinical documentation and treatment planning, but did not significantly change short-term patient outcomes. The study involved over 9,600 patients in Kenya and used a randomized controlled design to test the effectiveness of the AI tool.
Researchers from the University of Oxford have found evidence that Mars once had enormous magmatic systems deep beneath its surface, which could have produced complex crust and supported life. The discovery suggests that planets may not need plate tectonics to build habitable environments.
A new study discovered a previously unknown antiviral defense mechanism in sea anemones, revealing that animals may have evolved more than one way to fight viral infections. The findings suggest that fundamentally different antiviral strategies have emerged across the animal kingdom.
A new study by Osaka Metropolitan University found that levoglucosan, a chemical formed from biomass combustion, loses up to 88% of its mass in the atmosphere due to degradation and volatilization. This suggests that conventional analyses may misidentify emission sources, particularly in tropical areas.
A new study found that Pygmy Falcons require less than 1 km² to raise their young, contrary to long-held assumptions. The birds operate within a small breeding home range and coexist with Sociable Weavers in communal nests. This research provides a crucial baseline for understanding the spatial requirements of small raptors.
Researchers developed an oxygen-modified sulfide electrolyte that stabilizes interfaces while maintaining rapid lithium transport, leading to high-performance solid-state batteries. The approach improved battery stability, capacity, and cycling life, opening opportunities for safer and faster-charging solid-state batteries.
Researchers directly observed Meissner effect in 2D van der Waals superconductors, providing evidence of superconductivity in low-dimensional systems. The study used a new high-sensitivity method to detect magnetic signals in ultrathin samples.
Research reveals bacteria rely on circadian clocks to organize colonies, controlling gene expression and pattern formation. The discovery has important implications for understanding bacterial ecology and improving plant growth.
A team of researchers has found that the energy of light used to excite spin defects in hexagonal boron nitride affects their performance, leading to a threefold boost in contrast and calculated DC magnetic field sensitivity. The study also reveals a trade-off between emission stability and signal strength.
A new peptide agonist, beta01, has been designed to target the kappa opioid receptor with high efficacy and reduced β-arrestin signaling, offering improved safety profiles for chronic pain and pruritus treatment. The study demonstrates a structure-based rational design approach for biased KOR agonists.
Researchers at HKUST have developed a novel GenAI framework called Decoupled Generation and Registration (DGR) that can produce high-fidelity virtually stained images even when training image pairs are imperfectly aligned. DGR demonstrated stronger overall performance in image quality and structural fidelity across multiple tasks compa...
Researchers at Flinders University have found evidence of 7000 years of Aboriginal mining at Sugarloaf Hill in South Australia's Riverland region. The study sheds light on the traditional practices and trade networks of Aboriginal people in the area.
Researchers found that consuming vitamin K1-rich foods like leafy greens reduces the risk of chronic obstructive pulmonary disease (COPD) by 16%. Vitamin K1 may activate a protein protecting lung tissue, while fibre and antioxidants in greens boost its effect.
A new study reports a residue-free electrolyte additive, sodium trifluoromethanesulfinate (NaSO₂CF₃), designed to improve initial efficiency, cycle life, and manufacturability in sodium-ion batteries. The additive improved Coulombic efficiency from 82.6% to 96.0% and maintained capacity retention after 600 cycles.
A new study by Flinders University researchers has identified key research priorities to enhance recognition and support for unpaid carers in Australia. The priorities include recognition, early identification, timely access to services, and post-care support, as well as carer self-care and wellbeing.