Georgetown University researchers discovered a method to enhance the function of T cells, making them more effective in killing cancer cells. By inhibiting PARP, an enzyme that detects DNA abnormalities, scientists can boost the body's immune response against tumors.
Researchers propose a roadmap for using transcranial focused ultrasound to study consciousness, enabling precise manipulation of brain activity and determining cause-and-effect patterns. This technology may help address the hard problem of consciousness by probing neural circuits that generate sensations, thoughts, and feelings.
A team of material scientists created a machine learning model that predicts gas-sensing performance using first-principles calculations. The model achieved a prediction accuracy of 96% in five-fold cross-validation and F1 scores of 1.000 and 0.933 in independent test sets.
JMIR Publications' JMIR Neurotechnology journal now accepts submissions on novel technological advances for neurological disorders. Researchers can submit review articles exploring emerging technologies, such as neurofeedback, neurosurgery, and brain-machine interfaces.
A team of researchers from Chonnam National University has developed a novel superpixel-based virtual sensor framework for full-field vibration measurement. The approach offers robust and accurate motion estimation without the need for physical markers or contact sensors, making it suitable for large-scale infrastructure monitoring.
Researchers at Institute of Science Tokyo have discovered a stable superfluid that inherently hosts singularities known as exceptional points. The study reveals how dissipation can stabilize this unique superfluid phase, which features a finite order parameter and emerges deep inside a strongly interacting phase.
Researchers identified cilia-mediated Hedgehog signaling as a key regulator of tooth development. The study found that disrupting Cilk1 levels can lead to stepwise changes in tooth formation and morphology, including extra teeth or fused molars. This discovery may support earlier diagnosis for children with ciliopathies.
Pangenomics is the study of many different genomes from one specific species, providing a holistic picture of natural variation and mutations. A new data structure and compression technique, PanMAN, enables researchers to handle vast genetic data scales by encoding additional biologically relevant information.
Researchers developed an algorithm using whole-genome sequencing to detect homologous recombination deficiency, a type of DNA-repair defect vulnerable to PARP inhibitors. The approach identified genetic mutations beyond BRCA1 and BRCA2, promising more accurate patient selection for cancer treatment.
A new study in Circulation: Population Health and Outcomes journal found that TV characters were more likely to receive CPR than real-life counterparts. This discrepancy highlights the need for accurate depictions of hands-only CPR on television.
Astronomers have spotted an ancient galaxy that was slowly starved of fuel by a supermassive black hole. The galaxy's lack of cold gas prevented it from forming new stars, despite its relatively young age. Repeated episodes of heating and gas removal by the black hole likely drained the galaxy's fuel in as little as 16-220 million years.
A California statewide study found that an expanded school-based tobacco prevention program was associated with significantly lower rates of smoking and vaping among middle and high school students. Students in funded schools were 20% less likely to use tobacco overall and 23% less likely to vape.
A new study from University of Southern Denmark reveals that weight loss improves the health of fat tissue, reducing inflammation and immune cell activity. Moderate weight loss also promotes the formation of new and healthier fat cells, leading to improved insulin sensitivity.
Researchers have imaged a beautiful shock wave around a dead star, RXJ0528+2838, which challenges our current understanding of how dead stars interact with their surroundings. The team found that the white dwarf has been expelling a powerful outflow for at least 1000 years, driven by its strong magnetic field.
A Japanese research team has developed a biohybrid approach that works inside the body, transforming engineered skin into a visible indicator of internal biological states. The system leverages the body's natural skin regeneration to support long-term biomarker monitoring, providing a visual readout without blood sampling.
Research from Karolinska Institutet found that alpha frequency determines body ownership by modulating temporal integration of bodily signals. Faster frequencies led to higher temporal resolution, while slower frequencies caused broader timing differences.
A study analyzed 169 US TV episodes that portrayed hands-only CPR since 2008 and found nearly half showed outdated practices. Most cardiac-arrest victims receiving hands-only CPR on-screen were white men, while women and Black and Latino people are less likely to receive the intervention in real life.
Researchers propose threshold levels for safe cannabis use, aiming to guide consumption and reduce harm. The recommended limit is 8 THC units per week, above which the risk of developing cannabis use disorder increases.
A new study published in CANCER found that men are more likely to have advanced disease and high myeloma load at diagnosis compared to women. Men were also less likely to have low bone mineral density and had different chromosomal abnormalities, which may contribute to the sex disparity in multiple myeloma risk.
Scientists at VIB and KU Leuven discovered a molecular process that enables motor neurons to maintain protein production, which fails in ALS. By restoring protein synthesis in axons, they reduced disease-related damage in ALS models.
Research from Radboud University Medical Center and colleagues demonstrates the value of targeted tumor analysis of DNA in colorectal polyps. This study provides valuable insights into genetic predispositions, including APC mutational mosaicism and BRAF gene mutations.
New research suggests that mobile health interventions tailored to individual needs can reduce harms associated with heavy drinking and cannabis use. Studies demonstrate the effectiveness of personalized feedback and protective behavioral strategies in reducing substance use risks, paving the way for innovative digital interventions.
Healthcare professionals in Canada assess applicants for medical assistance in dying (MAiD) using a careful and individualized approach. They consider the patient's life circumstances, support networks, and personal preferences when determining eligibility. The assessment process is often legally and morally complex, requiring provider...
Researchers redesigned a superconducting solenoid to significantly reduce spherical aberration and improve electron beam emittance. The new design achieved a 47% reduction in transverse emittance under high-intensity beam conditions.
A new metamaterial design enables real-time stiffness visualization and self-sensing capabilities, paving the way for intelligent systems. The research team created a linear relationship between stiffness and active hinges, allowing for precise tuning and adaptation in mechanical systems.
A team from Chongqing Medical University developed a model that integrates sMRI and fMRI data to predict treatment responders, achieving high accuracy rates. The dual-branch graph attention network (DBGAN) captures coordinated brain changes linked to emotion regulation and memory processing.
A new study from Murdoch University found that 66% of participants with Complex Regional Pain Syndrome (CRPS) experienced migraines that started or worsened after CRPS onset. This research highlights the connection between CRPS and migraine, suggesting a possible common cause for both conditions.
A tiny sensor developed by KAUST researchers can detect hazardous head impacts with 360-degree accuracy, distinguishing minor bumps from severe blows. The device's innovative design allows it to operate without power or routine upkeep, paving the way for next-generation wearable safety systems.
Researchers developed a novel theory that enables precise control of heat conduction in materials with asymmetric microstructures. This innovation has potential applications in energy harvesting and protecting heat-sensitive electronics.
The research team led by DGIST Professor Su-Il In developed a high-performance next-generation betavoltaic battery with an energy conversion efficiency of 10.79%. This is a significant improvement over the previously reported highest efficiency for perovskite-based betavoltaic batteries.
Astronomers have discovered that black holes don't just consume matter — they manage it. Researchers found that black hole binary systems switch between powerful jets and energetic winds—never producing both simultaneously—and both types of outflows carry away comparable amounts of mass and energy.
A new study assesses the EU Energy Performance of Buildings Directive through a social justice lens, highlighting how renovation policies can widen existing social inequalities. The Composite Building and Social Vulnerability Index reveals markedly different levels of vulnerability across EU countries.
A novel deep learning model, LA-TextCNN-BiLSTM, has been developed to improve the accuracy of automatic disease classification using ICD-11 for Chinese Electronic Medical Records (EMRs). The model achieved an 83.86% accuracy rate and demonstrated robust performance in multi-label classification.
Researchers have developed a strategy to enhance the stability of CsPbI3 perovskite nanoplatelets by incorporating formamidinium, which improves bulk thermodynamic stability and surface ligand binding. This approach leads to highly oriented superlattices with improved linear polarization of light emitted.
Researchers detected up to 500 microscopic plastic particles per square meter per day in a rural woodland area, almost twice as much as in an urban location. The study reveals that trees and vegetation capture airborne microplastic particles from the atmosphere.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
Researchers in Hong Kong will have greater opportunities to share their work with a global audience through an open access agreement between JULAC and Taylor & Francis. The partnership enables OA publishing in over 2,000 journals without payment of an OA article publishing charge.
A research team at KAIST has proposed an AI-driven approach to solve the long-standing mystery of gene function. The team suggests combining computational biology with experimental biology to discover gene functions, leveraging tools like AlphaFold and generative AI.
A new bipolar cusp-like pulse-shaping algorithm has been proposed to reduce pile-up events and improve energy spectrum accuracy. The algorithm achieves real-time processing of millions of signals per second and demonstrates high precision in neutron counting.
Researchers developed a Bayesian neural network framework to predict thorium-232 fission yields, addressing sparse data gaps and incorporating physical constraints. The approach demonstrates strong agreement with experimental measurements and offers a systematic method for nuclear data evaluation with quantified uncertainties.
A machine-learning-based algorithm developed by Tokyo Metropolitan University researchers can accurately count sister chromatid exchanges (SCEs) in chromosomes, giving a more objective measurement. The accuracy rate is 84%, which could help diagnose disorders like Bloom syndrome with greater consistency.
Shaun Gleason, director of the Partnerships Office at Oak Ridge National Laboratory, has been appointed to Tennessee's AI Advisory Council. He brings decades of experience advancing the use of AI technologies in various fields, including scientific discovery and manufacturing.
Employment outcomes for working-aged people with disabilities reached record-highs in November and December 2025, indicating a potential push past the plateau experienced since mid-2023. The employment-to-population ratio decreased from 39.8% to 38.9%, while labor force participation rate remained at near-record levels.
Researchers found that vermicomposting reduces antibiotic resistance genes by 70-95% and mobile genetic elements by up to 68%. The process uses earthworms to transform raw manure into a stable, high-value fertilizer.
A new review highlights the growing threat of environmental antimicrobial resistance, which can spread through wastewater plants, farms, and oceans. The authors call for integrated surveillance to track resistance genes and prioritize traits that drive health risk, such as mobility, host pathogenicity, and multi-resistance.
A new study reveals that biodegradable plastics like PLA introduce a transient but intense risk window during breakdown, while conventional plastics like PVC pose a persistent threat as long-lived hubs for antibiotic resistance. The research highlights the need for considering the full life cycle of plastispheres in risk assessments.
A new review highlights the challenges of composite pollution in facility agriculture, where heavy metals, microplastics, and antibiotic resistance genes interact to affect soil organisms, crop growth, and consumer health. The authors call for more integrated assessment frameworks and sustainable control strategies.
Researchers used 'proxies' from the geological record to show that intense rainfall events were less regular during the Paleogene Period, which saw extreme warming. This challenges common assumptions about how wet places become wetter and drier with climate change.
The US has more than 4 million miles of rivers, but existing regulations only account for less than 20% of total river length. Freshwater conservation strategies have historically focused on land use and development, leaving gaps in protection measures for lakes, rivers, and wetlands.
Dr. Jennifer Rood, Associate Executive Director for Cores and Resources, takes on interim leadership role at Pennington Biomedical Research Center while an international search for the next full-time Executive Director is underway. She brings over 30 years of experience in obesity and chronic disease research.
Researchers at Duke University have created a new method to use analog radio waves to boost energy-efficient edge AI, enabling devices to run powerful AI models without heavy chips or distant servers. The approach, called Wireless Smart Edge networks (WISE), achieves nearly 96% image classification accuracy while consuming significantl...
A new study by University of Cincinnati researchers found that men's sense of fulfillment at work is linked to their partners' views on money. Couples who align on the values of money tend to have higher job satisfaction, while those with differing perspectives experience lower job fulfillment.
A team of scientists developed a simple biochar-based technology to strip self-toxic chemicals from pepper growing soils and restore healthy seed germination. The engineered material, HRP CBC, consistently outperformed other treatments in removing toxic phenolic acids and achieving at least 50% removal within two hours.
Researchers developed ultrasound-responsive in-situ antigen nanocatchers that efficiently capture tumor antigens, activating dendritic cell maturation and migration. This system achieved high primary tumor inhibition rates and complete distant tumor regression in a mouse model, providing a universal personalized immunotherapy platform.
A new study suggests that durvalumab may offer a promising treatment option for limited-stage small cell lung cancer patients, extending overall and progression-free survival. However, the therapy's high cost poses significant challenges to sustainability and access in the real-world setting.
Artificial intelligence is transforming water quality management by detecting subtle biological changes and triggering timely responses. AI-based sensors can analyze signals directly in the field for near real-time water quality assessment, predicting harmful algal blooms and pathogen outbreaks.
A new study from Aalto University found that online shopping is more strongly linked to stress than reading news or watching adult entertainment. Social media use and gaming also correlated with increased stress levels, while time spent on news sites reported lower stress levels.
A study by Oregon Health & Science University found that states with abortion restrictions have worse maternal health outcomes for patients using fertility treatment. The research analyzed over 400,000 births conceived through fertility treatments and found a statistically significant increase in serious maternal health complications.
A study by Cornell University researcher Merrick Osborne found that asking a marginalized person for help during a prejudice confrontation increases their emotional burden. This can lead to negative perceptions of the ally and decreased willingness to associate with them in the future.
Researchers discover hydroperoxides form from α-keto acids in clouds, rain, and aerosol water when exposed to sunlight, influencing atmospheric hydrogen peroxide levels and particle formation. The study provides a new framework for understanding hydroperoxides' role in the atmosphere.