Researchers developed MULTI-evolve, a framework for efficient protein evolution that applies machine learning models to predict beneficial mutations and their combinations. The approach identified function-enhancing mutations and tested their pairwise combinations, demonstrating improved efficiency in protein engineering.
Consuming virgin olive oil, but not refined olive oil, improves cognitive function and increases gut microbiota diversity in older adults. The study suggests that extra virgin olive oil's impact on brain function may be due to its effects on the gut microbiota.
A new method to steer AI output uncovers vulnerabilities and potential improvements. The researchers identified 512 concepts within five classes and improved LLM performance on narrow tasks.
Researchers developed an ultrathin mesh of conductive wires to help lab-grown pancreatic cells mature and function properly. The approach, called 'cyborg' transplants, has the potential to expand the supply of new tissue and reduce rejection risk.
Researchers from the University of Southern Denmark have identified a new virus in a common gut bacterium that appears more frequently in patients with colorectal cancer. The study demonstrates a statistical association between the virus and colorectal cancer, but its role is still unclear.
A new spinosaurid species, S. mirabilis, with a distinctive scimitar-shaped crest has been discovered in Niger's central Sahara, adding to the understanding of spinosaurid evolution. The fossil find challenges the long-held hypothesis that these fish-eating theropods lived in an oceanic habitat.
A new national study by the University of Southern California's Race and Equity Center found that 94% of professional athletes believe they should be allowed to engage in political activism. The study highlights the power of pro athletes' platforms and encourages them to use their influence to promote racial justice and activism.
Researchers at Michigan State University have created the first simulation that reproduces the two-lobed shape of contact binaries naturally with gravitational collapse. This finding suggests that the formation process is surprisingly simple and not rare.
The new guideline provides a clinical classification system to assess the severity of acute pulmonary embolism, which can lower oxygen levels in the blood, damage lung tissue, and put serious strain on the heart. Prompt diagnosis and timely treatment are crucial to prevent severe complications such as cardiac arrest and death.
Researchers from the University of British Columbia argue that forests can alter the frequency and probability of floods, including major events. They call for a shift in how flood impacts are evaluated, moving away from single event comparisons and toward assessing how forests affect flood risk over time.
Scientists have created a way to hear a single molecule 'sing' using infrared-integrated STM. This technique combines infrared excitation with scanning tunneling microscopy, allowing for the detection of individual molecular vibrations.
Researchers analyzed tumour samples from almost 500 domestic cats across five countries, identifying specific driver genes that lead to cancer development. The study found similarities between cat and human cancers, including a common driver gene associated with worse prognosis in humans.
A new Spinosaurus species discovered in Niger suggests a third phase of evolution for the massive fish-eating dinosaurs. The fossil find indicates that spinosaurs like S. mirabilis specialized as shallow water predators in northern Africa and South America.
The Harvard team developed a new microfabrication method to produce high-performance, curved optical mirrors with extremely smooth surfaces. The mirrors can control light at near-infrared wavelengths, enabling fast and efficient quantum networking.
Researchers developed a universal vaccine formula that provides broad protection against respiratory viruses, bacteria and even allergens. The vaccine is delivered intranasally and works for a wide spectrum of respiratory threats, including SARS-CoV-2 and common hospital-acquired infections.
Researchers at Harvard's John A. Paulson School of Engineering and Applied Sciences have developed a new fabrication method for printing robotic devices with long filaments featuring precisely placed hollow channels. This allows the device to bend and deform in predetermined ways, enabling the creation of soft robots with predictable s...
A new study uses metabolic modeling to predict which probiotics will successfully establish themselves in a person's gut and how prebiotics affect short-chain fatty acid production. The findings demonstrate the utility of these models for personalized probiotic and prebiotic interventions.
Researchers created 'cyborg' organoids that combine stem cell-derived islets with stretchy electronics to study glucose regulation and maturation of α and β cells. The device enhances glucose responsiveness and reveals how it's affected by chemicals and circadian hormones.
Researchers at the University of Turku developed a unified theory guiding the design of more efficient and sustainable devices. The work reveals that squeezing light too tightly inside OLEDs can reduce performance, and optimal efficiency is achieved through a delicate balance of material and cavity parameters.
Researchers have engineered a novel CAR-T cell that can be switched off on demand using a cancer drug, offering improved safety and efficacy. The new system, known as DROP-CAR-T, uses a clinically approved drug to disrupt tumor cell binding, preserving the cells for continued treatment.
Researchers found that discharges to hospice after ICU admission increased from 5.6% to 6.8% over the study period, while in-hospital mortality trends remained stable. This shift suggests a real change in how end-of-life care is delivered to seriously ill patients.
New research from Cranfield University analyzed the environmental impact of fresh apples sold in the UK, finding that imports from water-stressed regions like South Africa and Spain have significantly higher water scarcity impacts. The study suggests regional sourcing can help manage trade-offs across the supply chain.
Researchers found that regulatory T cells can be redirected to protect tumors instead of the body. Blocking P2RX7, a molecule released by stressed cells, helps immune cells work more closely with B cells and leads to better outcomes.
The partnership aims to accelerate the development of fluoride salt-cooled high-temperature reactors, which use molten fluoride salt coolant with TRISO fuel. ORNL will provide expertise and access to specialized facilities for review and evaluation, as well as manufacture components for reactor development and testing.
Researchers at Columbia University Irving Medical Center will create genetic tests to diagnose congenital lymphatic disorders, aiming to improve treatments and save lives. The CLARUM project aims to identify new genetic mutations and increase the predictive value of genetic testing for these diseases.
A University of Missouri study reveals that private dark pools attract inexperienced investors and allow companies to delay sharing bad news, increasing the likelihood of sudden stock price crashes. Dark pools also enable accounting manipulation by allowing managers to hide bad news through unusual accounting adjustments.
Dr. James R. Downing will transition to a faculty role at St. Jude in 2026, leading the institution's global mission after an unprecedented growth period. He played a pivotal role in advancing childhood cancer research and treatment worldwide.
A new review highlights the potential of viral mimic systems and virus-like particle technologies to accelerate vaccine development and improve global health equity. These innovative approaches enable local testing of vaccine candidates and antiviral therapies, strengthening regional preparedness for future outbreaks.
A nationwide study found that periods can trigger severe pain in many women and girls with sickle cell disease, leading to emergency department visits and hospitalizations. The study's authors recommend a routine menstrual history screening as part of annual sickle cell care and connecting patients with reproductive health specialists.
PhD candidate Michael Gomes is developing advanced nanoscale drug carriers to deliver chemotherapy more effectively to brain tumours. His research focuses on polydopamine nanoparticles and the glymphatic system to reach tumours directly, potentially increasing drug concentrations and reducing toxic effects.
Researchers at RMIT University have developed a flexible nylon-film device that generates electricity from compression and can withstand extreme forces. The breakthrough could provide a durable alternative material for piezo components in vehicles and support new technologies for traffic-management sensing on roads.
Scientists have made a breakthrough in understanding flexibility at the molecular scale, finding that individual molecules contribute to material stiffness. This discovery could inform the design of faster and more efficient flexible electronics.
Paul Plummer, UT College of Veterinary Medicine dean, joins the 2026 Class of Fellows of the American Academy of Microbiology. He was recognized for his scientific achievements and contributions to microbiology and antimicrobial resistance research.
Researchers at Max Planck Institute of Molecular Physiology have discovered the genetic origin of the tiny and precise centromeres in brewer's yeast. They found that these centromeres evolved from a likely intermediate stage and were shaped by retrotransposons, providing a concrete genetic explanation for their unique structure.
Researchers developed a molecular monitoring approach to identify patients with muscle-invasive bladder cancer who can safely preserve their bladder without compromising cancer outcomes. The study found that ultra-sensitive testing of tumor-derived DNA in blood and urine may help predict metastatic risk and identify patients with an ex...
A University of Tennessee team will evaluate the persistence of RNA interference-based biofungicides in controlled environment agriculture. The study aims to generate data for evidence-based decisions on genetically engineered organisms and their ecotoxicological effects.
The 2026 College Hiring Outlook report from Drexel's LeBow College of Business revealed that internships and co-op experiences are integral to hiring practices. Employers surveyed across industries reported a cautious openness toward AI in career development, while prioritizing authenticity and demonstrable skills.
A study published in Molecular Psychiatry reveals that kinases MNK1 and MNK2 have distinct functions in the brain, regulating different behaviors such as social contacts and object recognition. The findings suggest that targeting each kinase individually may be more effective for treating neurological disorders.
A study found that patients value AI-based interpretation for routine situations due to its speed and convenience, while remote video interpretation is preferred for emotionally sensitive or high-stakes conversations. Patient trust, autonomy, and perceived control drive interpreter preferences.
Researchers analyzed ancient maize cob fragments to reconstruct agricultural practices from nearly a millennium ago. The study reveals that the Chincha Kingdom used seabird guano as a high-powered fertilizer, transforming a desert landscape into one of the most productive riverine valleys in Peru.
A new tool developed by Southwest Research Institute and National Science Foundation's National Center for Atmospheric Research provides a first step toward forecasting space weather weeks in advance. The PINNBARDS framework connects surface observations of solar active regions to deep solar magnetic dynamics, offering potential for su...
The American Educational Research Association (AERA) has selected 34 outstanding scholars as the 2026 class of AERA Fellows. These researchers have made significant contributions to education research, advancing knowledge and promoting its application to improve education.
A UC Santa Barbara research team has developed a method to efficiently synthesize non-natural amino acids and apply them to peptide construction. This technique provides greater access to amino acids beyond the 22 found in nature, opening up new possibilities for biochemists, medical researchers, and materials scientists.
Researchers have quantified zinc concentration in teeth using 3D X-ray tomography systems. They found a sharp increase in zinc concentration from the outside to the inside of the tooth, particularly near the pulp. This study has implications for dental care and material selection.
A new study from the University of Michigan found that bureaucratic hurdles and racial disparities significantly impact access to victim compensation for adult survivors of sexual assault. The study revealed that Black and Indigenous women's claims were less likely to be approved, while excessive documentation requirements also contrib...
Researchers at the University of East London identified a critical weakness in Industrial Internet of Things networks that can destabilize factories and safety-critical infrastructure. Attackers can exploit subtle 'delay attacks' to quietly disrupt coordination, making timing just as important as information in highly automated systems.
Researchers used a virus-based CRISPR system to edit the gatekeeper enzyme HMGR in petunias and lettuce, unlocking natural metabolic control for enhanced aromatic compounds and health-promoting antioxidants. The result was more vigorous growth, stronger floral fragrance, and increased nutritional value.
A new Immunology Center will accelerate discoveries in muscle immunology and immune responses to gene therapies. Klaudia Kuranda brings expertise in immunology, onco-immunology, and leadership experience to the center.
A new study from Houston Methodist suggests that the outer area of the retina may hold clues to early Alzheimer's detection, potentially allowing for non-invasive diagnosis and monitoring. Researchers found that changes in retinal cells and blood vessels can indicate the onset of AD years before symptoms appear.
A Rapid Outbreak Assessment published by ECDC and EFSA concludes that the likelihood of exposure to contaminated infant formula is low due to ongoing recalls. Most affected children experience mild symptoms, but infants under six months are more vulnerable to dehydration and electrolyte disturbances.
Researchers at Penn State develop novel technology to isolate and recover dysprosium, a critical rare earth element used in semiconductors and other applications. The new approach uses cellulose-based nanocellulose to selectively separate dysprosium from other elements, promoting a more environmentally friendly and efficient method.
Researchers identify UBR5 as a critical tumor suppressor that modulates Snail's stability, facilitating metastasis. UBR5 maintains epithelial phenotype by targeting Snail for degradation, while its deficiency promotes Snail stabilization and metastatic cascade.
Researchers identify PAK1 as a key player in colorectal cancer progression through its ability to stabilize mRNA of oncogenic factors. Targeting PAK1 inhibits proliferation, migration, and invasion, promoting the degradation of these transcripts and sensitizing tumors to standard-of-care treatments.
A new study has determined that the Ubeidiya site in the Jordan Valley dates back at least 1.9 million years, revealing a significant shift in our understanding of early human history. The discovery suggests that ancient pioneers were established in the Levant at the dawn of humanity's global expansion, using diverse stone tools.
Advances in Pollinator Research is a community-driven peer-reviewed journal championing research from underrepresented regions and taxa. It aims to find and amplify solutions to pollinator decline through transdisciplinary collaboration.
Leadership behavior is the foundation of an authentic green workplace culture, with employees responding to leaders' environmental priorities and trusting their intentions. Trust is the mechanism that turns leadership intent into action, leading to higher levels of voluntary green behavior.
Researchers developed a novel route for transforming molecular crystals into quantum dot monoliths, mimicking geological weathering on a tiny scale. Uniformly sized zinc oxide quantum dots form within the original crystal structure, preserving its shape.
Researchers identified USP30-AS1 as a key oncogenic regulator in breast cancer, promoting cell proliferation, cycle progression, and tumor growth. Silencing USP30-AS1 suppresses proliferation, induces apoptosis and senescence, and reduces tumor growth in xenograft models.
Lucciana Mikaela Cáceres Holgado, a University of Kansas physics and astronomy double major, has been awarded the second annual Marian H. Rose Research Scholarship for her exoplanet research and community involvement. The $15,000 scholarship supports her graduate research in environmental sciences.
Researchers have developed an artificial DNA base pair that relies on halogen bonds, enabling stable structures and recognizing naturally occurring enzymes. This breakthrough expands the genetic alphabet and could open up new possibilities in synthetic biology.