Researchers developed an AI-powered methodology to identify and count target viruses more efficiently than previous techniques. The new approach uses electrochemical impedance spectroscopy and machine learning to separate signals from noise, enabling quick and accurate readings across a wide range of titers.
Researchers found that people follow a two-stage process, sampling behaviors at first and committing once enough evidence accumulates. The Tolerance Principle predicts when people have seen enough regularity to treat a pattern as a rule despite some exceptions.
A new study analyzing Mount Everest expeditions spanning more than a century has found that death rates among climbers have declined significantly in recent decades. The research highlights improvements in safety measures such as fixed ropes, better weather forecasting, and increased oversight among climbing teams.
The study found that invasive reed facilitates the development of mosquito larvae, leading to increased adult populations. Removing invasive reed and restoring native vegetation can help mitigate this impact.
A study coordinated by the University of Trento has identified a gene therapy for individuals with cystic fibrosis caused by a specific mutation, offering new hope for those currently dependent on drugs. The therapy uses advanced gene editing technology to correct the DNA mutation responsible for the disease.
Researchers found memory cells in nasal tissue can reactivate to fight influenza, reducing viral replication and protection against more severe illness. These immune cells can be used to develop better nasal vaccines.
A new analysis by researchers at the University of Texas MD Anderson Cancer Center demonstrates that combination therapy consisting of fludarabine, cytarabine and G-CSF (FLAG) plus gemtuzumab ozogamicin (GO) or idarubicin (IDA) delivers strong long-term outcomes for patients with CBF-AML. The five-year overall survival rate reached 74%...
Researchers found that even in degraded forests, tree species can regenerate quickly, but vulnerable species are replaced by more resilient generalists, leading to a loss of diversity. The recovered areas are vulnerable to extreme events and climate change impacts, highlighting the need for forest conservation strategies.
Researchers estimate sepsis occurs in 1.3% of pediatric hospitalizations, resulting in a 10% mortality rate, and urges the need for immediate recognition and treatment. The study's findings highlight the importance of awareness among families to improve child survival rates.
A study has identified novel risk factors and therapeutic targets for Parkinson's disease, offering hope for future treatments. The researchers used a combination of computational and experimental approaches to distinguish between gene function changes that promote or protect against the disease.
Researchers from Duke University analyzed data from over 50,000 Fitbit users across four states and found that daylight saving time does not affect overall daily step counts. However, they did notice a shift in steps taken between morning and evening, likely due to adjustments made to match the new daylight availability.
The American Geriatrics Society (AGS) has selected 24 members for their outstanding commitment to advancing high-quality, person-centered care for older adults. These individuals have made meaningful contributions to the field of geriatrics through scholarship, advocacy, and clinical excellence.
A new study from Rice University transforms lunar regolith simulant into a valuable building resource, strengthening advanced composite materials by up to 30-40%. The innovative approach reduces dependence on Earth-supplied materials, increasing the feasibility of longer missions and infrastructure development.
A team from Oak Ridge National Laboratory used large-format additive manufacturing to create high-precision molds for advanced nuclear reactors, lowering costs and speeding deployment of new plants. The project demonstrates the potential of digital manufacturing to cut weeks off the schedule while meeting strict nuclear standards.
A USF study finds that children ages 9 to 12 engage with AR headsets in a more exploratory and intuitive way than adults, highlighting a mismatch between adult-designed systems and child-centered design. This difference has implications for educational applications of AR, which may require more flexible and creative interaction methods.
Researchers from the Salk Institute found that astrocytes play a crucial role in fragile X syndrome symptoms. Correcting dysregulations in star-shaped brain cells improved some symptoms, including reduced seizures and restored molecular balances in a mouse model of FXS. The study validates the importance of studying astrocytes in FXS r...
The study reveals how copper nitrite reductase converts nitrite to nitric oxide gas through an ordered sequence, clarifying electron, substrate, and proton coordination. The research demonstrates the potential of combining XFEL technology with advanced software for individual-atom resolution structures.
The new program addresses unique challenges faced by female athletes, including injury prevention, hormonal health, pelvic floor issues, and heart health. It offers coordinated care through a team of experts in orthopedic sports medicine, primary care, and other specialties.
Researchers at INRS have developed a photochemical synthesis strategy for metal-organic frameworks (MOFs), enabling precise control under ambient conditions. The approach significantly reduces energy consumption, leading to enhanced photocatalytic activity and improved structural precision.
Researchers at Stanford Medicine successfully cured Type 1 diabetes in mice by combining a blood stem cell and pancreatic islet cell transplant with a gentler pre-transplant treatment. The approach resulted in an immune system made up of cells from both the donor and recipient, preventing disease progression and cure.
A new targeted therapy has shown strong results in preclinical studies against aggressive childhood and adult cancers, eliminating tumours and stopping cancer spread. The therapy targets the IL1RAP protein, which is found on cancer cells but largely absent from normal tissues, allowing for precise delivery of treatment.
A new freeze-dried blood product called Thrombosomes has shown promise in treating traumatic brain injuries by reducing swelling and bleeding. The product, derived from platelets with trehalose preservation, has been tested on mice and found to be effective in stabilizing damaged blood vessels.
Researchers at the University of Nebraska-Lincoln have developed a promising new vaccine approach against highly pathogenic bird flu (H5N1) that demonstrates strong efficacy in both mice and dairy cattle. The vaccine platform protects against multiple H5N1 strains and generates immunity in both the bloodstream and respiratory tract.
Researchers at UCLA mapped how Down syndrome disrupts prenatal neuron development, leading to cognitive and sensory processing differences. The study found altered developmental sequences and cell populations that may contribute to the condition's effects.
A study of 3,000 Punjabi Sikhs identified new molecular pathways contributing to cardiovascular disease, including a link between lipid metabolites and immune cell signaling. These findings offer insights into diverse molecular origins of cardiometabolic disease and potential pathways for designing innovative therapies.
Researchers develop a new approach to selectively insert nitrogen into specific carbon-hydrogen bonds in organic molecules, enabling efficient and scalable synthesis of amines. This method simplifies the production of valuable chemicals used in pharmaceuticals, agrochemicals, and polymers.
Researchers at the University of Pennsylvania have designed a tiny robot that uses a knotted fiber to store energy, which is released when heated. The robot can leap meters into the air, flip mid-flight, and even plant seeds with high local pressure.
A new study found that the heart's constant beating may actively suppress tumor growth in cardiac tissues by altering gene regulation and reducing proliferation. This mechanical force also reshapes the cancer cell genome's regulatory landscape, influencing whether cells can proliferate.
A new study reveals that colossal octopuses were top predators in Cretaceous oceans, with species like Nanaimoteuthis jeletzkyi growing up to 19 meters in length. The discovery suggests these creatures played a significant role in shaping marine ecosystems, potentially preying upon large vertebrate apex predators.
New research has found that immature red blood cells can import heme from surrounding cells, overcoming long-standing assumptions about heme and red blood cells. This discovery could lead to new therapeutic approaches for inherited genetic blood disorders such as β-thalassemia.
Researchers found that people with severe obesity and heart failure have weakened heart muscles, which can be reversed through weight loss. The study identified a chemical change in a protein called troponin I as the underlying cause of this condition.
Researchers at Kyoto University discovered a previously unrecognized feature in near-fault seismic records of large earthquakes: a distinct stopping phase. This phase represents a systematic signal associated with the termination of rupture, demonstrating that many near-field recordings contain this coherent stopping phase.
New high-altitude measurements have revealed a hidden population of extremely small, organic-rich aerosol particles in the lower stratosphere. These ultrafine aerosols are found to dominate the surface area available for heterogeneous atmospheric chemistry and act as a significant condensation sink.
New research found that maintaining in-person work provided psychological benefits, while job loss and employment disruptions significantly increased depression risk. Older adults with stable employment experienced significant mental health benefits, particularly women who shouldered increased caregiving responsibilities.
Early octopuses were gigantic predators that hunted at the top of the food web, alongside large marine vertebrates. They had powerful jaws with extensive wear marks, indicating a strong biting force and aggressive feeding strategy.
A new paper in Neuroscience & Biobehavioural Review proposes a comprehensive neurobiological model of affective tactile memory, suggesting that emotionally meaningful touch is stored in the brain in powerful and lasting ways. This research opens a new window into how early and everyday tactile experiences influence our emotional lives.
Two-dimensional nanomaterials enhance M/NEMS sensors' mechanical strength, electrical conductivity, thermal stability, and biocompatibility. Their applications in biosensing and medical diagnostics show rapid response and high-sensitivity detection.
Researchers found that a dense piece of lithospheric mantle beneath the Hangay Mountains broke off and sank into the deeper mantle about 125-114 million years ago. This 'foundering' event triggered melting of the mantle, generated magma, and caused the overlying crust to dome upward.
A recent study reveals that men have lower fertility rates than women worldwide. The research attributes this shift to declining mortality rates, narrowing mortality gaps, and sex-selective abortions in some countries. As a result, the proportion of men in the population is increasing, presenting challenges for society.
Researchers at FAU are developing artificial muscles that can be controlled by light using tiny molecular machines. The technology enables the creation of intelligent materials with programmable properties, such as rigidity and elasticity under different wavelengths of light.
The article presents a conceptual design for an in-situ energy station on Mars, which could alleviate power fluctuations and distribution issues. The system utilizes the Martian atmosphere as a working medium for power generation and storage, with potential to save over 20 tons of payload in future manned missions.
A new UK study found that many heat-related deaths occur during lower-level alerts, highlighting widespread gaps in awareness and response. Older people are particularly vulnerable to these risks, with lower engagement with warnings leaving them exposed.
Researchers identified a new compound, Apilimod, that prevents hepatitis E virus infection by blocking a key cellular process, PIKfyve. This approach may offer a more effective treatment with lower risk of resistance development.
The EBRAINS Roadmap Symposium will bring together the global neuroscience community to shape the EBRAINS 10-Year-Roadmap. A total of 159 submissions from 134 unique contributors across 25 countries have been received, reflecting the momentum of Europe's digital neuroscience landscape.
A recent study published in Cell Reports identified a key pathway through which the hormone FGF21 influences eating behavior and energy balance. The findings highlight the importance of nutrition in brain function and suggest that FGF21-based therapies could be optimized to target specific brain circuits.
Researchers are close to building a 'virtual gut' capable of predicting responses to diet, drugs, and microbiome-based therapies. A new review outlines an analytical framework for host-microbiome multi-omics studies, covering preprocessing, feature selection, data integration, predictive modeling, and evaluation.
Researchers have made significant breakthroughs in prostate cancer treatment with new imaging techniques and targeted therapies, including a PSMA-targeting antibody and a CD44v6-targeting radiotherapy. These advancements aim to improve patient outcomes by tailoring diagnosis and treatment to individual needs.
Researchers review data-driven leakage diagnosis methods connecting single pipeline analysis with energy transmission systems, focusing on nonlinear mapping and spatiotemporal feature extraction. Advanced signal processing and multi-modal fusion techniques improve detection accuracy in complex scenarios.
A study led by Chinese Academy of Sciences reveals climate change leads to unprecedented sensitivity of soil inorganic carbon pools. Climate-driven effects on SIC dynamics are quantified using a novel process-based model, showing significant losses of up to 307 Tg C in topsoil.
A new study from the University of New Hampshire found that consumer trust in smart technologies like Alexa or Ring's video doorbells depends on a person's political beliefs. Conservatives tend to be more open to sharing their data, while liberals show more concern about privacy risks.
The study reveals that DUX family proteins undergo liquid-liquid phase separation to drive the transition to a totipotent-like state. This process is mediated by dynamic nuclear condensates, which act as specialized transcriptional hubs to activate totipotency-specific genes and retrotransposons.
The UFZ research team has developed a two-stage electrochemical purification process to efficiently degrade short-chain PFAS in water. This process uses electro-adsorption and electro-oxidation to concentrate and break down PFBA, resulting in easy separation of the fluoride by-product.
A new human cell model has been developed to realistically replicate the pathological processes of neurodegenerative dementias, such as Alzheimer's disease and frontotemporal dementia. The model exhibits tau aggregates and neuronal damage typical of these diseases, opening up prospects for drug development and therapy.
A new study from the University of Copenhagen shows that Danish retailers can generate a net financial gain of €0.3-€0.8 per kilo by selling surplus food at discounted prices. Donating food to organizations that redistribute it to vulnerable people is often cheaper than disposal, with savings of €0.10-€0.20 per kilo.
Human tumor organoids advance cancer modeling by preserving patient-specific characteristics and functional drug responses. The review highlights the need for quality control, cross-laboratory standardization, and ethical governance to enable broader real-world implementation.
A new measurement technique using nanomembranes and infrared light detects tiny amounts of substances in minutes, reducing sampling time by 100-fold. The technology analyzes particles accumulating on a tiny membrane, heating it up when certain wavelengths are absorbed.
Conventional models fail to capture human-relevant immune responses, hindering therapeutic translation. Immune-inclusive microphysiological platforms recapitulate inflammation, fibrosis, and immune-stromal crosstalk.
Researchers used high-throughput RNA sequencing to identify many more insect viruses in mosquitoes, some of which are globally distributed while others are unique to specific continents. By studying viral small RNAs, they can discover new viruses and understand how mosquitoes enable viral disease transmission.
Disrupted ecosystems can increase risk for food security, water scarcity, health and well-being, crime, mass migrations, border breaches, and social unrest. Governments must protect natural infrastructure to safeguard citizens' basic needs and prevent ecological disruptions.
The Bial Foundation is launching a new call for Grants for Scientific Research 2026/2027 in psychophysiology and parapsychology. The maximum grant amount is €60,000 per project, with applications open until 31 August 2026.