A study by the Medical University of Vienna found that plastic particles can increase intestinal inflammation and disrupt the gut microbiome, leading to ulcerative colitis. The research shows that MNP exposure triggers a pro-inflammatory immune response and alters the balance of beneficial and harmful bacteria in the gut.
A team of researchers at Hokkaido University characterized the unique mechanics of Arcella, a shelled single-celled amoeba, to move skillfully across various surfaces. They found that differences in traction stress distribution control straight-line and sideways movement.
Researchers found that patients with clonal hematopoiesis of indeterminate potential (CHIP) had a significantly higher incidence of heart failure and ischemic cardiovascular disease after cancer treatment. CHIP, a condition characterized by age-related variants in blood stem cells, puts patients at increased risk for heart complications.
A recent study found that the RSVpreF vaccine does not pose a significant risk to pregnant women, providing reassurance for those who wish to be vaccinated. The interim report presents data from a large cohort of pregnancies with vaccine-seeking behavior, and results suggest no notable adverse effects.
A Bar-Ilan University study reveals that individuals with social anxiety may feel better when they believe others' opinions are fixed rather than changeable. Adopting a fixed mindset reduced stress and improved performance in social interactions.
The Rhine River transports an estimated 3,000-4,700 tonnes of macrolitter towards the North Sea each year. Plastic pieces account for only around 15% of the overall litter mass.
A University of California San Diego team is developing a first-of-its-kind stem cell-based gene therapy for Friedreich’s ataxia. The $7.4 million grant will support safety studies, manufacturing and clinical planning needed before applying to test the treatment in patients.
Researchers have developed a multiscale framework to engineer robust electric double layers, enhancing the performance of zinc anodes in aqueous rechargeable batteries. The study achieves over 4,700 cycle life and 90% capacity retention after 800 cycles using a low-cost sugar-derived additive.
Researchers at Sanford Burnham Prebys found that transplanted stem cells develop neurons with unique codes to navigate and form connections in the brain. These codes guide the growth of axons and explain why most neurons of a particular subtype send axons to specific brain regions.
Researchers at University of British Columbia have successfully grown specialized immune cells called helper T cells from stem cells in a controlled laboratory setting. This breakthrough could lead to more accessible and effective off-the-shelf treatments for various conditions, including cancer, autoimmune disorders, and infectious di...
Researchers found plastics in 7 of 10 green sea turtles, with macroplastics dominating the diet, and estimated origin of ingested plastics to extend beyond the turtles' migratory range. This study provides evidence for transboundary marine plastic pollution affecting sea turtles.
New research reveals hybrid schistosomes are undermining existing disease control strategies by emerging faster than previously recognized. These hybrids can display altered biological traits linked to virulence and transmission potential, complicating diagnosis and treatment.
A study found that maternal vaccinations against influenza and pertussis are associated with reduced hospitalization or emergency department visits in infants under 6 months. Implementing maternal vaccination campaigns can enhance infant health outcomes, addressing low vaccination coverage.
DORA Community Edition aims to democratize access to state-of-the-art research tools, foster global collaboration, and accelerate innovation in biotechnology. The open-source version is designed to streamline the drafting of academic papers and other research-related documents with a team of agile AI agents.
Researchers at Nanjing University of Aeronautics and Astronautics created an active metal metamaterial that can bend and recover its shape, enabling aircraft wings to morph smoothly in flight. The material is lightweight, strong, and capable of adjusting its shape on demand.
The JMIR-Bibsam partnership has seen a 40% increase in annual publishing by Swedish authors, with over 130 digital health articles published without author payment. The renewed agreement simplifies the publishing process, allowing corresponding authors to publish immediately upon publication.
The collaboration aims to address bottlenecks in solid tumor manufacturing and accelerate advancement into clinical trials. City of Hope's investigational gene-modified CAR T cell therapy targeting glioblastoma will be evaluated using Cellares' automated manufacturing platform and quality control system.
A single dose of IV iron dextran is the most cost-effective treatment option for women with heavy menstrual bleeding and iron deficiency anemia. The study found that IV iron dextran improves quality of life and reduces costs compared to oral ferrous sulfate.
A global study of 2,636 firms across 31 countries found that stronger ESG disclosure and performance correspond to higher intrinsic value. This aligns with theoretical analysis and signaling theory, highlighting the need for companies to communicate substantive progress honestly.
Researchers mapped nearly 400 genetic regions regulating circulating proteins, identifying 18 with a likely causal link to T2D. These findings provide new insights into disease biology and could lead to earlier and more accurate diagnoses, as well as treatments tailored to African populations.
Melanie Rutkowski's pioneering research may lead to novel immunotherapy treatments for ovarian cancer by understanding how faulty cellular signaling interacts with the microbiome. The grant aims to enhance immune system's ability to kill cancer cells and improve patient outcomes.
A new study introduces a semi-transparent, color-tunable solar cell designed for flexible surfaces and windows. The 3D-printed pillar structure allows for precise control over light transmission and appearance, enabling better integration of solar technology into building façades and curved surfaces.
A Korean research team has developed a design method for core materials in all-solid-state batteries, improving performance while reducing costs. By introducing divalent anions like oxygen and sulfur, they enabled faster lithium-ion transport within solid electrolytes, lowering energy barriers.
A new study found that bowel preparation procedures for colonoscopies can disrupt the gut environment, making mice more susceptible to infection and inflammation. The researchers hope to understand whether these procedures may put people with inflammatory bowel disease (IBD) at risk of exacerbation.
A high-protein diet rich in casein and wheat gluten can significantly reduce the amount of cholera bacteria able to infect the gut. The study found that these dietary components can suppress a key structure on the surface of cholera bacteria, making it difficult for the pathogen to colonize and cause harm.
Researchers at Jeonbuk National University propose hierarchical porous copper nanosheet-based triboelectric nanogenerators, demonstrating efficient energy harvesting and multifunctionality. The devices achieve a remarkable 590% increase in electrical output while maintaining stability over 100,000 repeated mechanical cycles.
Researchers develop new framework to evaluate monetary value of QALY, adjusting for age and lifetime quality of life. Analysis yields key findings on cost-effectiveness of healthcare policies, highlighting benefits of promoting good health throughout life.
Researchers have discovered a complex regulatory circuit involving SRSF1, AURKA, and MYC that promotes aggressive pancreatic cancer progression. The circuit, which involves alternative splicing, can be targeted with an antisense oligonucleotide to reduce tumor cells' viability and trigger apoptosis.
A new study has created a comprehensive model of neutrino mapping, revealing that most stars in the Milky Way generate and emit these ghost particles. The research provides valuable insights into the universe, offering a unique way to explore cosmic phenomena.
Researchers identified specific gut bacteria and metabolic pathways that drive alcohol production in patients with auto-brewery syndrome, a rare condition causing intoxication without drinking. A stool-based test may serve as an alternative to monitored blood alcohol testing for diagnosis.
Scientists from ISTA and Brandeis University develop a geometric framework that predicts viable structures in self-assembling particles. The 'high-dimensional convex polyhedron' tool helps identify constraints that prevent certain outcomes, offering insights into designing custom-made nanomaterials.
Researchers at MIT have designed a pill that can report when it has been swallowed, using a biodegradable radio frequency antenna to communicate with an external receiver. This technology could improve medication adherence for patients who need to take immunosuppressive drugs or treatment for extended periods.
A research team at The University of Osaka has identified a parallel pathway involving CENP-C for centromere specification and function. This process is vital for ensuring chromosomes are structured and genes are expressed appropriately.
A Curtin University-led research found that households in 26 countries burn plastic as an everyday energy source, posing serious health risks. The study highlights the need for targeted interventions to improve sanitation, access to modern cooking energy, and culturally relevant options.
A study published in Nature Microbiology identified specific gut microbes and metabolic pathways responsible for producing high levels of alcohol in patients with auto-brewery syndrome. The researchers found that stool samples from patients produced significantly more ethanol than those from unaffected individuals or healthy controls, ...
Researchers have developed a new way to boost the immune system's response to cancer by using specially engineered antibodies. The antibodies work by clustering multiple immune cell receptors, amplifying the signal that tells T cells to attack cancer cells.
A team at Graz University of Technology found that espresso is a favourable and environmentally friendly substitute for uranyl acetate, which is highly toxic and radioactive. The results showed equally good quality images under the microscope with coffee staining.
Research shows that conservation efforts can be more effective if they focus on why people buy ivory rather than just promoting its illegality. Studies suggest that targeting specific audiences and using behavioural theory can help change consumer behaviour.
Researchers at KIMM and KIST developed a cuffless, non-invasive blood pressure sensor using ultrasonic technology. The sensor measures blood vessel diameter changes to calculate blood pressure values, offering high accuracy and flexible wearability.
Researchers identified 48 OR genes, 2 V1R genes, and 135 V2R genes in hagfish, indicating functional roles in smell perception. The discovery overturns the assumption that true V2Rs evolved only in jawed vertebrates.
A new study of over 32,000 US Veterans found that longer treatment with medications for opioid use disorder is associated with a greater probability of short- and medium-term survival. The benefit continues to increase at least for four years of ongoing treatment.
A large study has demonstrated the significant benefits of lifestyle interventions in reducing the risk of gestational diabetes. Physical activity-based interventions, such as walking and strength training, were found to be the most effective in preventing gestational diabetes, with no adverse effects observed.
Marine mammal experts use drone-based thermal imaging to measure dolphin surface temperature and respiration rates, detecting biologically meaningful changes in physiological state. The study validates the accuracy of drone measurements under controlled conditions, paving the way for safer health monitoring of marine mammals.
A new framework proposes managing AI-related risks by treating workers as co-designers of workplace transformation. The framework integrates job crafting, participatory oversight, and expanded WHS definitions to address relational harms and promote human labour values.
A novel optical microneedle device developed by researchers can quantify glucose levels in ultra-trace samples with high precision, offering a potential solution for blood-sampling-free clinical testing. The device features a functional hydrogel at its tip that reversibly binds to glucose, enabling accurate analysis without consuming t...
This study explores the feasibility of preoperative VEGFR-TKI plus ICI therapy for advanced renal cell carcinoma, finding improved cNSS rates and preservation of renal function. The therapy also induces robust immune activation through increased CD8⁺/CD20⁺ infiltration and tumor microenvironment remodeling.
A study found that maintaining a bedroom temperature of 24°C at night reduces stress responses and helps the heart recover from heat exposure. Dr. Fergus O'Connor's research suggests this can be especially beneficial for individuals aged 65 years and over.
A new review found that social and interpersonal factors significantly impact Australian women's body image concerns after childbirth. Supportive partners, strong social networks, and clear guidance from healthcare providers are protective factors, while appearance-related comments and sociocultural pressure can worsen issues.
A new study found that population bottlenecks can fundamentally reshape how cooperation evolves and persists in complex microbial societies. The researchers discovered that stringent bottlenecks favored fruiting body formation and growth, while relaxed bottlenecks led to an overall increase in competitive fitness.
The study highlights the need to incorporate virus-based indicators into wastewater treatment optimization and public health risk assessment. Viral communities persist throughout treatment, with several taxa showing high prevalence from influent to effluent.
Researchers developed a new type of bio-hybrid actuator using locust hind legs, achieving remarkable leaping capabilities and ultra-low power consumption. The actuators enable high maneuverability and autonomous self-righting capabilities, making them suitable for confined space exploration and precision medical delivery.
Researchers discovered that plant-derived phenolic acids can act as powerful antibiotic adjuvants by boosting tetracycline uptake and disabling bacterial defense systems. These compounds restore the efficacy of an aging antibiotic and offer a faster and more affordable alternative to developing new antibiotics.
Rising temperatures trigger a surge in carbon-degradation genes, favoring pathways that rapidly consume easily degradable carbon. This shift has significant implications for predicting carbon fluxes under climate change.
Research reveals that incomplete water disinfection primes bacteria to take up resistance genes, contributing to antibiotic resistance persistence. Sub-lethal stress enhances bacterial survival and acquisition of resistance genes from the environment.
A modular machine learning framework using LoRA fine-tuning can accurately predict single organic reactions and handle multiple reaction types. The model demonstrates high prediction accuracy comparable to expert experience, achieving results on classic reaction datasets and showing strong adaptability.
A portable biosensor developed at La Trobe University can rapidly detect toxic per- and polyfluoroalkyl substances (PFAS) in water. The device provides a simple yes or no result, allowing for quick and easy screening of water samples, particularly in regional and remote areas where monitoring is challenging.
A new UCLA study combines human and animal research to identify chlorpyrifos as a potential environmental cause of Parkinson's disease. Long-term residential exposure to the pesticide increases the risk of developing the condition by more than 2.5 times.
A single-dose oral cholera vaccine called PanChol has completed a phase 1 clinical trial with positive results, offering hope for combating the devastating disease globally. The vaccine was developed by Mass General Brigham and shows promise in preventing severe vomiting and diarrhea caused by Vibrio cholerae bacteria.
A study by Radboud University Medical Center found that pregnant women vaccinated against whooping cough transfer antibodies to their newborns, which provide long-lasting protection. This discovery supports the World Health Organization's recommendation to maintain whole-cell vaccines in low- and middle-income countries.
A new study found that 4.9 million adults in Great Britain have recently used a drug to support weight loss or were interested in using one in the near future. The usage far exceeds NHS England's initial goal of prescribing these drugs to 220,000 people over three years.