The study reveals that diabetes poses a significant challenge for healthcare systems and economies worldwide. The economic impact of diabetes is substantial, with an estimated global cost of up to $152 trillion, equivalent to 1.7% of GDP, when informal care is factored in.
A study at Kindai University has identified a single gene in eggplant that provides resistance to begomovirus infection. This finding holds promise for developing naturally protected crop varieties, reducing the need for insecticides and promoting sustainable food production.
Mesenchymal stromal cell (MSC) therapy has been validated as a transformative solution for rheumatoid arthritis through preclinical and clinical evidence. MSCs target RA via immunomodulation, tissue repair, low immunogenicity, and targeted migration, resulting in sustained benefits with minimal side effects.
The study highlights the multifunctional natural substitute for antibiotics in swine production, demonstrating broad antimicrobial, antioxidant, anti-inflammatory, and immune-regulating effects. Dietary supplementation improves intestinal barrier integrity, increases growth metrics, and reduces fecal E. coli.
Researchers have developed a new approach to suppressing the shuttle effect in transition metal fluoride cathodes, leading to unprecedented discharge plateau voltage and high-performance thermal battery cathodes. The study focused on thermal batteries and utilized an ion-sieving concept to achieve selective confinement.
A three-year study by the University of Stirling has shown that Himalayan balsam disrupts riverbank stability, causing erosion during high-flow periods. This leads to increased sedimentation, damaging habitats and wildlife, and changes to river shape and structure.
A team of researchers has observed a massive galaxy cluster that challenges existing models of the universe's evolution. The cluster's unusual structure and high density of cold, neutral hydrogen gas suggest a different history than previously thought. This discovery raises questions about the fate of large structures in the universe.
Researchers developed a novel thin-film electrolyte design using samarium-doped cerium oxide, achieving record-setting oxide-ion conductivity at medium temperatures. This innovation addresses key technical limitations of existing solid oxide fuel cells, paving the way for widespread adoption.
Researchers found that the West Antarctic Ice Sheet retreated at least five times during warmer periods millions of years ago, indicating its extreme vulnerability to future warming. The study analyzed deep-sea sediments and identified 14 prominent melt events between 4.65 and 3.33 million years ago.
The 2026 ACMG Annual Clinical Genetics Meeting will bring together experts in medical genetics and genomics to present groundbreaking research on personalized medicine. Journalists can access leading experts and timely story ideas on emerging technologies like AI in genetics and gene editing, with complimentary registration available.
A study found that increased bone morphogenetic protein signaling is linked to impaired neurogenesis in Alzheimer's disease, particularly in female mice. The research suggests that activation of BMP signaling may be a key factor contributing to the sex-based differences observed in AD.
Researchers found that close to half of all dementia cases would not arise without the APOE gene's influence, and potentially more than 90% of Alzheimer's disease cases are linked to variants in this single gene. The study highlights the APOE gene as a powerful target for drug development.
A global report highlights fragmented data systems and lack of standardization hindering botanic gardens' contribution to biodiversity conservation and scientific research. Researchers call for a unified, equitable global data system to transform how living collections manage and share information.
Researchers developed a new method to measure how effectively antibiotics kill bacteria, crucial for treating complex infections. The 'antimicrobial single-cell testing' method predicts treatment success by observing individual bacteria under different conditions.
Researchers identified changes in RNA molecules involved in cell's splicing machinery, causing retinitis pigmentosa in ~30-40% of patients with genetic disorder. Variants in five non-coding RNA genes were found to be responsible for the disease, offering a new diagnostic pathway for families worldwide.
Researchers created an 'atlas' of immune cells in bone marrow cancer that provides insights into how the immune system interacts with cancerous plasma cells. The knowledge can improve survival predictions and guide treatment decisions for patients with multiple myeloma.
Researchers discovered a subcellular environment within the giant virus Acanthamoeba polyphaga mimivirus that enables efficient translation of viral mRNAs despite mismatched codon usage with its host. This specialized environment alleviates the unfavorable translation condition, allowing for optimal viral replication.
Researchers have discovered new genetic causes of inherited blindness, identifying changes in RNA genes as a key factor. This breakthrough provides clarity for dozens of families globally and opens new possibilities for diagnostics and counseling in hereditary conditions, offering hope for affected individuals and their loved ones.
The Earth's ocean stored more heat in 2025 than in any year since modern measurements began, with a record-high increase of 23 Zetta Joules. The findings indicate stronger ocean warming trends since the 1990s and highlight the importance of reducing emissions to mitigate climate change.
A new study from Karolinska Institutet reveals that long-term type 2 diabetes can cause red blood cells to become directly harmful to blood vessels. The researchers found that microRNA-210 plays a crucial role in this process, and its levels in red blood cells may serve as a biomarker for early detection of cardiovascular complications.
A new sea surface height prediction model, GTU-Net, combines deep learning and physics-informed constraints to improve accuracy. The model outperforms existing mainstream models across multiple metrics and demonstrates higher accuracy up to 60 days.
A team of scientists creates a dynamically reconfigurable topological photonic platform that can control local topological properties in real-time using spatially patterned optical pumping. This enables the topological edge mode to be steered, redirected or blocked entirely by adjusting an external pump profile.
A new study found that federal rental assistance distributed during the COVID-19 pandemic improved mental health and increased the appropriate use of mental health care among low-income renters. The program reduced symptoms of anxiety and depression, and more recipients sought mental health services when needed.
Researchers develop Sb/Nb co-doped TiNb2O7 anode for fast-charging lithium-ion batteries, achieving 140 mAh g^-1 at 20 C and 500 stable cycles at -30 °C. The material enables practical pouch cells with high capacity retention after extensive cycling.
Researchers have developed a PPy@N-TiO2 Z-scheme heterojunction photoelectrode that harvests sunlight to co-drive sulfur redox, delivering high performance and scalability. The innovation enables efficient lithium-sulfur batteries with potential applications in solar-assisted EV packs and stratospheric drones.
A new study found that more than one-in-four adults worldwide may be eligible for GLP-1 use, with women and older individuals among the most eligible. The research emphasizes the need to prioritize global access to these medications, particularly in low- and middle-income countries where obesity rates are highest.
A study analyzing personal injury claims data for England and Wales found that mental trauma succeeds 1 in 7 dog-related injuries, resulting in the need for time off work and/or loss of earnings. Most incidents occurred in public spaces, with unrestrained dogs being a common cause.
A new review highlights major advances in aptamer-based biosensors for viral detection, offering faster, cheaper and more portable testing. These biosensors use short DNA or RNA strands called aptamers that bind to viruses with high precision.
A study of 168 second-time mothers found that those who breastfed were less likely to experience depression and anxiety 10 years after pregnancy. Each week of lifetime exclusive breastfeeding was associated with a 2% lower likelihood of reporting depression and anxiety, after accounting for influential factors.
A new Japanese study uses a two-country model to investigate the impact of tariff policies on economic growth outcomes across countries. The researchers found that similar trade policies can lead to very different growth outcomes across countries, depending on a country's existing industrial structure.
A study by researchers from the University of East Anglia found that leisure crafting interventions can improve work outcomes, including creativity and meaning, in working adults. Participants who engaged in hobbies reported feeling more fulfilled and creative at work, with a stronger impact on older employees.
Climate change is releasing ancient antibiotic resistance genes from glaciers into rivers and lakes that supply drinking water, posing a significant risk to human health. The 'glacier continuum' concept highlights the need for monitoring programs and early-warning frameworks to track resistance gene spread.
A study published in Biochar found that optimized biochar application could reduce China's cropland nitrous oxide emissions by as much as 50 percent. The researchers analyzed data from over a decade of field studies across China and identified optimal biochar strategies to deliver substantial climate benefits.
The US nuclear power renaissance faces a blind spot in uranium fuel supplies, which are tight, vulnerable to geopolitics, and expensive. New fuel forms for advanced reactors offer promise, but scaling them affordably could squeeze conventional fuel markets.
Researchers found a neuroendocrine mechanism linking ovarian status to brain signals controlling sexual receptivity in female teleosts. Progesterone analogs restored sexual behavior but not ovulation, suggesting a direct neural pathway for hormone reception.
A national study reveals that pharmacists are at a significantly higher risk of suicide compared to the general population. The study found that job-related stress and mental health issues are key factors contributing to these deaths, highlighting the need for improved workplace policies and resources.
The American College of Lifestyle Medicine endorses the new Dietary Guidelines' emphasis on whole food as a key element in preventing lifestyle-related chronic diseases. The guidelines recommend increasing fruit and vegetable intake and limiting added sugars, refined grains, and processed foods.
The Rice Brain Institute has awarded seed grants to four collaborative projects that unite Rice faculty with clinicians and scientists across the Texas Medical Center. The grants support innovative research in brain science, mental health, and neurological disease.
A clinical trial by UC San Diego School of Medicine found that personalizing cancer treatments using molecular testing improves treatment success. The study used advanced genomic sequencing to identify unique tumor DNA profiles and developed personalized treatment plans, resulting in better treatment results for patients.
Researchers compared seedling germination, growth and nutrient uptake in pure food waste substrate, commercial potting mix and blends with varying ratios. Mixtures with less than 50% food waste compost produced better results.
A new study found that only a quarter of reproductive health experts prescribe self-administered injectable contraceptives, despite its safety and effectiveness. The study identified barriers such as concerns about patient ability, medication availability, and lack of standardized counseling approaches.
The funding will support research at UCLA's David Geffen School of Medicine, College of Letters and Science, and Fielding School of Public Health. The studies aim to inform evidence-based regulation and public health priorities.
A new UCLA study finds that the Patient Safety Indicator 04 (PSI 04) metric is fundamentally flawed when applied to emergency stroke care. The researchers argue that the metric incorrectly flags unavoidable complications of severe strokes, rather than problems with the procedure itself.
A recent paper highlights the need for defense mechanisms covering software, programs, and physical components of quantum computing systems. Key findings include the risk of crosstalk, intellectual property theft, and lack of end-to-end protection, emphasizing the need for safeguarding quantum computers from ground up.
Researchers developed a smartphone-based assessment approach to detect improvements in daytime insomnia symptoms, detecting treatment effects more powerfully than traditional methods. The new method leverages real-time, multimethod assessment and shows potential for personalizing sleep medicine care.
Researchers found science fiction and genre elements were popular among readers, with top authors including Ursula K. Le Guin and Octavia E. Butler. The analysis also revealed trends driven by news events and the selection of canonical authors for the Seattle Reads program.
Researchers at UH Seidman Cancer Center have developed a reliable tool to predict early biochemical response in metastatic hormone-sensitive prostate cancer patients. This framework enables clinicians to identify high-risk patients at diagnosis, guide early treatment discussions, and potentially improve patient outcomes.
A new qualitative study highlights the profound toll of caregiving on family members of individuals with acute leukemia. Caregivers described living in two worlds, one dominated by cancer and another defined by their personal lives. The findings underscore the need for caregiver support as standard cancer care.
Researchers at Columbia University found that people form stronger memories when in familiar locations, as the brain creates a deeper and richer memory for events. The study also suggests that prior knowledge is crucial in learning and that neuro-imaging can identify gaps in knowledge that need to be repaired.
A new study has identified unique protein signatures linked to ethnicity and changes in physical activity, which may influence cardiometabolic health. The research found that South Asian individuals may face a higher risk of cardiometabolic disorders due to distinct immune, inflammatory, and metabolic pathways.
A new approach to assessing patients with disorders of consciousness combines six assessment techniques, including high-density EEG and functional MRI. The study reveals that combining data from multiple techniques significantly improves model performance and provides a synthetic and precise assessment of patient outcomes.
Scientists discovered that authigenic clays played a crucial role in preserving the Ediacara Biota fossils. The unusual chemistry of the Ediacaran seawater helped to form these clays, which acted as cement, holding together sand particles and replicating the organisms' soft-bodied forms.
The Mount Sinai Health System has launched an AI-powered clinical trial-matching platform, PRISM, to help connect patients with life-saving trials. The platform uses machine learning to match patients with trials based on their electronic health records and diagnosis.
Researchers at UBC Okanagan developed a two-layer membrane filtration system that significantly reduces micro and nanoplastics in landfill leachate. The top layer uses chemical attraction and filtration to capture pollutants, while the lower layer repels remaining particles through electrostatic forces.
Leadership from Insilico Medicine will discuss its groundbreaking collaboration with Capgemini, showcasing Pharmaceutical Superintelligence in action. The company's diversified pipeline includes 40+ programs discovered using Pharma.AI, with positive topline results from a Phase IIa trial for idiopathic pulmonary fibrosis.
Researchers found that OTULIN, an enzyme regulating the immune system, drives tau formation and brain inflammation. Deactivating OTULIN halted tau production and removed it from neurons.
The study found that women with two to three children tend to live the longest, while those with an above-average number of children have shorter lifespan. Pregnancies between ages 24 and 38 were also linked to more favorable aging patterns.
A new sensor developed by the Universitat Politècnica de València can quickly detect scopolamine, a substance commonly used in chemical submission crimes, with high sensitivity. The sensor uses a molecular cage to trap specific molecules and generates a fluorescent signal proportional to the amount of scopolamine present.
A study of over 3,000 entrepreneurs in 18 European countries found that values related to independence, creativity, and novelty are linked to higher life satisfaction and lower psychological distress. In contrast, those motivated by financial success or status experienced lower life satisfaction and greater emotional strain.
A narrative review reveals that disaster-related prenatal maternal stress can lead to epigenetic modifications in offspring, affecting child health outcomes. Epigenetic markers show promise for shaping interventions to mitigate the effects of stress on health outcomes.