This year the Maryland Stem Cell Research Fund awarded 29 of 40 grants to Johns Hopkins researchers for the study of stem cell metabolism and regulation, the creation of new cell models for human diseases such as schizophrenia and Rett syndrome, which previously could be studied only in animals, and the development of new potential therapies.
Researchers whose preliminary data promised greater discoveries were awarded Investigator-Initiated grants. Jeff Bulte, Ph.D., professor of radiology, biomedical engineering and chemical and biomolecular engineering and a member of the Institute for Cell Engineering, hopes to develop a cell therapy for treatment of type 1 diabetes — an autoimmune disorder in which the immune system kills the insulin-producing cells that help regulate blood sugar. By developing cloaked stem and insulin-producing cells that can evade immune system detection, Bulte and his team hope to replace damaged cells and restore insulin levels in patients.
Grants were awarded to:
Several Johns Hopkins investigators were awarded Exploratory grants for researchers either new to the stem cell field or with untested but promising new ideas. Miroslaw Janowski , M.D., Ph.D., a research associate in radiology, plans to develop a stroke treatment by guiding newly introduced brain cells with magnets through blood vessels to the site of injury.
Exploratory grants were awarded to:
Postdoctoral trainees also will receive funding for research projects. A fellow in biomedical engineering, Pinar Huri, Ph.D., will use her award to develop bone grafts with blood vessels inside made from fat tissue-derived stem cells. The grafts would be used in patients with severely damaged bone in need of reconstructive surgery.
Postdoctoral grants were awarded to:
Johns Hopkins Medicine
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