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People with severe sleep apnea have significantly lower levels of the antimicrobial peptide LL-37 in their blood, indicating its potential as a biomarker for poor sleep quality

09.02.26 | PLOS

Plasma levels of antimicrobial peptide LL-37 as a biomarker of sleep quality in patients with obstructive sleep apnea: A clinical observational study

People with severe sleep apnea have significantly lower levels of the antimicrobial peptide LL-37 in their blood, indicating its potential as a biomarker for poor sleep quality. Credit: Quin Stevenson, Unsplash, CC0 (https://creativecommons.org/publicdomain/zero/1.0/)

People with severe sleep apnea have significantly lower levels of the antimicrobial peptide LL-37 in their blood, indicating its potential as a biomarker for poor sleep quality

Article URL : https://plos.io/4wKqqYY

Article title: Plasma levels of antimicrobial peptide LL-37 as a biomarker of sleep quality in patients with obstructive sleep apnea: A clinical observational study

Author countries: Japan.

Funding: The author(s) received no specific funding for this work.

PLOS One

10.1371/journal.pone.0355855

Plasma levels of antimicrobial peptide LL-37 as a biomarker of sleep quality in patients with obstructive sleep apnea: A clinical observational study

2-Sep-2026

The authors have declared that no competing interests exist.

Keywords

Health and Medicine Life Sciences Neurophysiology Neuroscience Sleep Sleep Apnea Sleep Disorders

Article Information

Journal

PLOS One

DOI

10.1371/journal.pone.0355855

Article Publication Date

2026-09-02

Article Title

Plasma levels of antimicrobial peptide LL-37 as a biomarker of sleep quality in patients with obstructive sleep apnea: A clinical observational study

COI Statement

The authors have declared that no competing interests exist.

Contact Information

Hanna Abdallah

PLOS

onepress@plos.org

How to Cite This Article

APA:

PLOS. (2026, September 2). People with severe sleep apnea have significantly lower levels of the antimicrobial peptide LL-37 in their blood, indicating its potential as a biomarker for poor sleep quality. Brightsurf News. https://www.brightsurf.com/news/8Y4G9P6L/people-with-severe-sleep-apnea-have-significantly-lower-levels-of-the-antimicrobial-peptide-ll-37-in-their-blood-indicating-its-potential-as-a-biomarker-for-poor-sleep-quality.html

MLA:

"People with severe sleep apnea have significantly lower levels of the antimicrobial peptide LL-37 in their blood, indicating its potential as a biomarker for poor sleep quality." Brightsurf News, Sep. 2 2026, https://www.brightsurf.com/news/8Y4G9P6L/people-with-severe-sleep-apnea-have-significantly-lower-levels-of-the-antimicrobial-peptide-ll-37-in-their-blood-indicating-its-potential-as-a-biomarker-for-poor-sleep-quality.html.