About The Study: In this contemporary cohort of women diagnosed with breast cancer at age 40 or younger, risk of isolated locoregional recurrence was relatively low (5.6%) at a median follow-up of 10.1 years, and significant differences were not seen by tumor subtype. Concerns for long-term risk of locoregional recurrence should not influence surgical decision-making with young women, irrespective of molecular subtype.
Corresponding Author: To contact the corresponding author, Laura Dominici, MD, email ldominici@bwh.harvard.edu .
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(doi:10.1001/jamasurg.2025.2324)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Surgery