Chinese medicine based on combinations of typically five to ten plants has a long tradition of use against rheumatoid arthritis, but few clinical trials have tested its potential. A review in the Journal of Internal Medicine outlines a strategy to analyze the ability of different mixtures of plants used in Chinese medicine to combat rheumatoid arthritis.
The strategy involves isolating the active components of individual plants and testing them alone or in combinations against key pathways of disease pathology, followed by experiments conducted in animal models of rheumatoid arthritis.
“A substantial number of our current drugs are natural products or derivatives thereof, and without doubt nature will continue to be a source of future discoveries,” the authors wrote. “Therefore continuous research based on the traditional use of plants is highly motivated. In our opinion, the strategy of starting from knowledge in traditional medicine, followed by the combination of in vivo evidence of efficacy and bioassay-guided isolation to understand the chemistry and pathways involved, is one effective way forward.”
URL Upon Publication: https://onlinelibrary.wiley.com/doi/10.1111/joim.13537
Additional Information
NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact:
Dawn Peters +1 781-388-8408 (US)
newsroom@wiley.com
Follow us on Twitter @WileyNews
About the Journal
JIM – Journal of Internal Medicine is a peer-reviewed scientific journal that publishes original clinical work from bench to bedside covering a broad field of its subspecialties. JIM features original articles, reviews and clinical updates.
About Wiley
Wiley is a global leader in research and education, unlocking human potential by enabling discovery, powering education, and shaping workforces. For over 200 years, Wiley has fueled the world’s knowledge ecosystem. Today, our high-impact content, platforms, and services help researchers, learners, institutions, and corporations achieve their goals in an ever-changing world. Visit us at Wiley.com , like us on Facebook and follow us on Twitter and LinkedIn .
Journal of Internal Medicine
Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis
20-Jul-2022