About The Study: In this study of 6.3 million older U.S. adults, the mRNA-1273 (Moderna) vaccine was associated with a slightly lower risk of several adverse events compared with BNT162b2 (Pfizer-BioNTech), possibly due to greater protection against COVID-19. Future research should seek to formally disentangle differences in vaccine safety and effectiveness and consider the role of frailty in assessments of COVID-19 vaccine performance.
Authors: Daniel A. Harris, Ph.D., of the Brown University School of Public Health in Providence, Rhode Island, is the corresponding author.
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(doi:10.1001/jamanetworkopen.2023.26852)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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