About The Study: In this systematic review and meta-analysis including 17 studies with 10.9 million vaccinated and 2.6 million unvaccinated children ages 5 to 11, mRNA COVID-19 vaccination was associated with lower risks of SARS-CoV-2 infections, severe COVID-19–related illnesses, and hospitalizations due to COVID-19. While vaccination, compared with placebo, was associated with higher incidences of adverse events, the overall frequency of severe adverse events was low.
Authors: Jun Yasuhara, M.D., of Nationwide Children’s Hospital in Columbus, Ohio, and Toshiki Kuno, M.D., Ph.D., of the Albert Einstein College of Medicine in New York, are the corresponding authors.
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(doi:10.1001/jamapediatrics.2022.6243)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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JAMA Pediatrics