About The Study: In adults with mild to moderate hypertension, treatment with zilebesiran, an investigational RNA interference therapeutic, across a range of subcutaneous doses at 3-month or 6-month intervals significantly reduced 24-hour mean ambulatory systolic blood pressure at month three in this phase 2, randomized clinical trial.
Authors: George L. Bakris, M.D., of University of Chicago Medicine, is the corresponding author.
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(doi:10.1001/jama.2024.0728)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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