The International Society for Stem Cell Research (ISSCR) today announced the 10 most downloaded papers of 2025 from Stem Cell Reports , its peer-reviewed, open-access journal. Together, these highly read articles reflect the extraordinary scientific range of the field – from foundational mechanisms of pluripotency and differentiation to translational advances in regenerative medicine, disease modeling, and bioethics – and underscore the journal’s role as a trusted platform for impactful stem cell science.
These top-downloaded papers exemplify Stem Cell Reports’ mission to publish science that is rigorous, transparent, and consequential – advancing discovery while informing clinical translation, policy, and public understanding.
To explore more articles, visit Stem Cell Reports .
About Stem Cell Reports
Stem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians. Stem Cell Reports is a Cell Press partner journal. Find the journal on X: @StemCellReports .
About ISSCR
With nearly 5,000 members from more than 80 countries, the International Society for Stem Cell Research ( @ISSCR ) is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.
Stem Cell Reports