A randomized trial found that a shorter radiation therapy course did not increase breast cancer recurrence or cosmetic issues, but may have quality-of-life benefits. The study suggests that women with small, completely removed tumors could potentially receive shorter, more convenient treatment.
Researchers developed a gene therapy combining radiation therapy and cisplatin to target tumor cells, resulting in significant regression with no additional toxicity. The treatment uses a modified cold virus to insert the TNF gene into tumor cells, enhancing anti-cancer effects.
A study of female radiologic technologists found that prolonged exposure to low dose radiation is associated with a higher risk of breast cancer mortality. Women who started working as radiologic technologists before 1940 were nearly three times more likely to die from breast cancer than those who began working in 1960 or later.
In a Phase I trial, patients receiving recombinant Angiostatin with radiation showed significant tumor regression and minimal toxicity. The findings support the safety of Angiostatin when combined with radiation therapy, paving the way for future trials of combination therapy.
Researchers evaluated 407 patients who had surgery to remove their cancer and were at high risk for recurrence. The study found no significant difference between radiation alone and chemotherapy plus radiation in reducing cancer recurrence or improving overall survival rates.
Researchers found that blocking ICAM-1 reduced inflammation and fibrosis in lungs treated with radiation. Mice genetically engineered to lack ICAM-1 showed fewer infiltrating leukocytes and less respiratory distress.
A recent study by Columbia researchers suggests that low doses of radiation can cause widespread mutations in living cells, even if they only affect a small percentage of the population. The findings highlight the importance of considering the 'bystander effect' when assessing radiation exposure risk.
Researchers at Massachusetts General Hospital found that a certain chemotherapy drug combination can increase the risk of lung inflammation in breast cancer patients. The study suggests doctors use extra caution when administering radiation therapy with paclitaxel, as it may lead to radiation pneumonitis in up to 14.6% of patients.
A new treatment regimen combining chemotherapy and radiation therapy significantly improved failure-free survival rates for patients with early-stage Hodgkin's disease. The study also found that staging laparotomy could be avoided, leading to better patient outcomes.
Researchers developed a prognostic model for patients with prostate cancer who have returned after surgery, identifying risk factors that predict treatment success. PET scans also showed promise in assessing lung cancer patients' response to radiation therapy.
Researchers found that prostate cancer patients who underwent seed implantation (brachytherapy) experienced more urinary, sexual, and bowel problems compared to those treated with high-quality conformal external-beam radiation. The procedure's invasive nature may contribute to the higher side effects.
Patients face increased risk of cancer progression due to inadequate staffing and technical support for advanced radiation therapies like IMRT and SRT. These high-tech treatments require specialized personnel and equipment, which can lead to longer waiting times and higher healthcare costs.
Scientists have identified small blood vessels as a key target of radiation therapy, allowing for higher doses with minimal side effects. The discovery could lead to improved treatment options for cancers treated with abdominal radiation therapy.
Researchers found that survival rates for primary eye cancer treatments are essentially the same, with a five-year survival rate of 82% for both radiation therapy and eye removal. The study's findings expand the capability of doctors to provide accurate diagnoses and state-of-the-art treatments.
Researchers have developed a new radiation therapy technique that shows significant improvement over traditional methods in treating brain tumors in infants. The treatment uses high-intensity synchrotron sources to confine x-rays to extremely narrow slices, resulting in reduced damage to surrounding tissue.
A new study by Cincinnati Children's Hospital Medical Center reveals that some children receive five times more radiation than necessary during CT scans. Researchers found that adjusting technical factors like tube current and pitch can significantly reduce exposure without sacrificing image quality.
A laboratory study found that vitamin E concentrations did not interfere with the killing of cancer cells by radiation therapy. However, the study's limitations mean that the impact on real-world treatment outcomes is unclear.
Researchers at NASA Langley studied various aspects of atmospheric science, including the tropical radiation energy budget, climate classification, and the impact of increased aircraft traffic on climate change. The study used data from the NASA Earth Radiation Budget Experiment (ERBE) to analyze the effects of weather and climate para...
A new radiation treatment technique targets head and neck tumors while sparing salivary glands, enabling patients to function more normally. Patients who received intensity-modulated radiation therapy (IMRT) experienced improved saliva flow and quality of life compared to conventional radiation therapies.
Researchers found radiation therapy to be both safe and effective in preventing cancer recurrence in women with BRCA1 or BRCA2 mutations. However, women with these genetic mutations were more likely to develop cancer in their unaffected breast.
Intensity modulated radiotherapy (IMRT) enables physicians to deliver targeted radiation doses to tumors, improving treatment outcomes for various cancers. By using advanced imaging techniques and computer algorithms, IMRT minimizes damage to surrounding healthy tissues.
Researchers found that patients with localized prostate cancer who received higher doses of radiation lived longer and had better local control of their cancer. The study, published in the Journal of Clinical Oncology, examined data from 1560 patients treated between 1975 and 1995.
Scientists have developed a new way to detect and quantify various types of radiation damage to DNA, including clusters of oxidized bases and abasic sites. The test could help assess radiation risks for astronauts, improve cancer therapy, and distinguish between normal living and low-level radiation-induced damage.
Researchers found that concurrent chemotherapy and daily chest radiation can help lung cancer patients live longer, with an average survival of 17 months. In contrast, sequential treatment resulted in an average survival of 14.6 months.
A study published in Urology suggests that patients treated with radiation therapy for prostate cancer have a high chance of being disease-free after four years, with minimal risk of recurrence. Patients with favorable prognoses also show a lower risk of treatment failure sooner than those with less favorable prognoses.
A new study has found a significant link between radiation exposure and an increased risk of multiple myeloma among nuclear workers, with older workers facing the highest risks. Workers exposed to ionizing radiation had a 3.5-fold higher mortality rate compared to those with lower exposures.
Researchers captured the first direct images of how high-energy X-rays break apart proteins, revealing specific chemical bonds vulnerable to radiation. This discovery may lead to new methods for preventing radiation damage and improving diagnostic tools for protecting against radiation exposure.
The Comprehensive Cancer Center at Cedars-Sinai has begun treating patients with a next-generation radiation therapy system that allows physicians to deliver precise, three-dimensional radiation treatments. This technology enables the delivery of full doses of radiation to tumors while protecting surrounding normal tissues.
Xie George Xu's 3D virtual man, VIP-Man, simulates radiation's effect on the skin, lens of the eye, optic nerve, and bone marrow with high accuracy. The model will enable accurate treatment planning for diseases requiring radiation therapy, revolutionizing radiation dosimetry in biomedical sciences and engineering.
Researchers found that blocking VEGF can significantly increase the effectiveness of radiation therapy against various types of cancer. The combination of anti-VEGF and radiation resulted in greater tumor reduction and slowed re-growth, even with minimal added toxicity.
Researchers at Thomas Jefferson University have found that radiation therapy helps patients with localized prostate cancer live longer. After examining the results of 1560 patients who received radiation therapy alone for prostate cancer, they discovered that those with high-risk disease benefited the most from higher doses of radiation.
A combination of radiation and chemotherapy treatment significantly increased overall survival in esophageal cancer patients, with 22% surviving at least eight years after treatment. The study found that this combined therapy was associated with longer survival compared to radiation therapy alone.
Researchers found that brief angiostatin exposure is sufficient to enhance the effects of radiation therapy. The combination of angiostatin and radiation resulted in significantly smaller tumors compared to other treatment groups.
Scientists discuss ways to use lightweight materials like hydrogen, boron, and lithium for radiation shielding. Researchers also explore using composites and polyamide binders for efficient protection against space radiation.
Researchers found that combining low doses of angiostatin with standard radiation therapy improves response rates without increasing toxicity. The combination causes significant growth inhibition in animal models, even in mice with large tumors.
A new device has been developed to protect patients from radiation exposure during CT scans, with significant reductions in breast and thyroid radiation exposure reported. The reusable protective garment is expected to cost less than $30, making it a potential game-changer for individuals at risk of increased lifetime breast cancer risk.
Researchers at St. Jude Children's Research Hospital are developing new brain tumor treatment protocols that use 3D imaging to accurately target tumors, reducing radiation doses and side effects. The protocols involve combining lower-dose radiation with chemotherapy to increase survival rates and minimize long-term damage.
Researchers have found that radiation exposure can be passed down through generations, affecting cell growth and reproduction. The study used a sensitive model to demonstrate that male mice exposed to radiation may pass on detrimental effects to their children, grandchildren, and great-grandchildren.
A recent study published in the American Society for Therapeutic Radiology and Oncology found that children with soft tissue sarcomas who did not respond well to chemotherapy can benefit from radiation therapy. The treatment was shown to improve survival rates by up to 40% in this patient population.
Researchers will present studies on permanent prostate implants and radiation therapy for various cancers, including prostate cancer, lung cancer, and cervical cancer. The presentation highlights the benefits of these treatments in improving survival rates and quality of life for patients.