Researchers found that Thalomid significantly improved symptoms for two-thirds of patients with chronic, steroid-dependent or unresponsive Crohn's disease. Common side effects included drowsiness and peripheral neuropathy. The study suggests a Phase III trial using Thalomid to treat Crohn's disease should be conducted.
A new color-coded chromosome mapping system devised by Julie R. Korenberg enables quick localization of known matching genes in humans using mouse DNA, greatly speeding up research into Down Syndrome and other human illnesses. The system has profound implications for the study of human diseases and the development of effective treatments.
Researchers at Cedars-Sinai Medical Center have made two groundbreaking discoveries. Firstly, they found that magnesium boosts cell proliferation in neural cells, potentially revolutionizing neural development. Secondly, a study identified a key receptor in human cells that may contribute to septic shock's immune response, offering new...
Two studies by Dr. Augusto Sola explore tidal volume measurements in neonates and propose a new definition for neonatal hypoglycemia, addressing critical issues in ventilator management and blood sugar screening.
Dr. Stefan-M. Pulst will present five scientific sessions on spinocerebellar ataxia and a new brain tumor-discovery, expanding treatment options for neurodegenerative diseases. His team mapped a new gene SCA10 to chromosome 22, causing loss of gait and limb control.
Scientists at Cedars-Sinai Medical Center have identified a key component of the immune system's over-aggressive response that leads to septic shock. The discovery confirms suspicions raised by recent studies and may lead to new treatment approaches for severe bacterial infections.
A study of 203 children with medulloblastoma found that a tried-and-true chemotherapy protocol provides better results than a newer method, while the quality of neurosurgery also affects long-term survival rates. The ability to remove nearly all of the tumor is critical for improved outcomes.
Researchers have localized a new gene, SCA10, associated with a rare form of inherited ataxia that also causes seizures in 20% of family members. The finding may shed light on the pathogenesis of epilepsy.
Researchers at Cedars-Sinai Medical Center have developed a groundbreaking brain cell transplantation technique aimed at treating neurodegenerative diseases such as Parkinson's disease, stroke, and epilepsy. By selectively growing and implanting targeted brain cells, the team hopes to promote healing and repair damaged brain tissue.
A clinical trial testing Azithromycin's effectiveness in preventing recurrent heart attacks found a promising link between the antibiotic and reduced inflammation. Researchers aim to determine if treating patients with Azithromycin for five days after an initial heart attack can prevent future heart attacks.
A Cedars-Sinai researcher has identified a gene associated with malignancy in brain, liver, breast, colon, kidney, and reproductive organs, but not in healthy adults. The discovery could lead to the development of a method to block the gene's expression using antisense technology, potentially stopping cancer before it spreads.
A Cedars-Sinai Medical Center clinical trial may offer a permanent, non-surgical cure for patients with Paroxysmal Atrial Fibrillation. Correctly identifying patients and eliminating trigger areas using radiofrequency energy could eliminate the need for long-term therapy and reduce stroke risk.
Researchers at Cedars-Sinai Medical Center have discovered that a combination of the diabetes drug Troglitazone and Accutane can permanently inhibit the growth of breast cancer cells and induce programmed cell death. The treatment has shown no adverse effects on healthy cells in laboratory studies and animal experiments.