Researchers found that thiazolidinediones (TZDs) and fibrates, commonly used to treat type-2 diabetes, may help counteract nicotine and alcohol addiction by activating specific receptors in the brain. These drugs stimulate PPAR-α and PPAR-γ receptors, reducing inflammation and increasing high-density lipoprotein (HDL) levels.
A new study found that genetic variants in dopamine-related genes increased the risk of smoking initiation in adolescents, while variants in nicotinic cholinergic receptors influenced persistence in adulthood. These findings could lead to genetic testing and targeted drugs for nicotine dependence.
The Canadian Cardiovascular Society and Canadian Heart Rhythm Society have published comprehensive guidelines on the use of genetic testing in managing patients with inherited heart rhythm disorders. The guidelines emphasize the importance of ordering physicians having a clear understanding of ethical issues surrounding genetic testing.
Researchers found that four microRNAs (miR-22, miR-138-2, miR-148a, and miR-488) are associated with panic disorder, regulating genes related to anxiety pathways in the brain. The study suggests a coordinated involvement of multiple risk genes, implying the existence of molecular 'switches' that control gene function.
A new study finds that larger hippocampal volumes are linked to recovery from post-traumatic stress disorder (PTSD), implying that the hippocampus may play a role in reversing damage caused by chronic stress. The research suggests that treatment for PTSD could be viewed as a form of brain restoration, rather than just symptom relief.
A recent study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that adolescent girls exposed to heavy alcohol use during their first trimester were three times more likely to develop conduct disorder. The study examined 592 adolescents and their mothers or caretakers, utilizing data from a long...
A special edition of Fungal Biology Reviews features 76 videos on fungal cell biology, produced by renowned researcher Professor Gero Steinberg. The collection is expected to become a primary teaching resource in the field.
A recent brain imaging study has identified the neural patterns that enable some individuals to perceive two colors at once while reading. The research, published in Cortex, suggests that the same areas of the brain responsible for processing color also support synesthetic experiences.
The new journal Environmental Development aims to provide solutions to regional environmental issues through rapid assessments and integrative approaches. It bridges the gap between natural sciences, social sciences, and policy makers to foster global action and knowledge sharing.
A new study has revealed the brain networks involved in person recognition using both face and voice information. The research found that specific regions of the left angular gyrus and right hippocampus are activated when recognizing people from combined visual and auditory cues.
A multidisciplinary team found that patients with tumors in the right parietal cortex struggled to process categorical spatial information, leading to errors in mental rotation tasks. The left prefrontal cortex was also affected, causing difficulties in setting up specific programs within the brain for task organization.
A new study suggests that grey matter volume in the cerebellum predicts cognitive ability, particularly in older adults. The study found a stronger relationship between brain volume in the cerebellum and general intelligence in men compared to women.
Researchers found that left-handed individuals showed no asymmetry in hand preference, suggesting a possible explanation: hemispheric specialisation for speech and language. Right-handed participants had trouble with bimanual tasks when using their right hand, indicating a bias towards choosing the correct hand.
Researchers have identified a genetic variation linked to bipolar disorder, suggesting that Piccolo contributes to the condition. The study used postmortem tissue and genome-wide association studies to find this link.
A recent study found that racial and ethnic minority adolescents are less likely to receive treatment for major depression. The research analyzed data from over 7,700 adolescents aged 12-17 and found significant disparities in treatment rates across different racial/ethnic groups.
The January/February 2011 issue of the Canadian Journal of Cardiology marks the beginning of a partnership between Elsevier and the Canadian Cardiovascular Society. The issue focuses on atrial fibrillation, including the long-awaited Canadian Cardiovascular Society Atrial Fibrillation Guidelines.
A mega-analysis of brain imaging data found that individuals with bipolar disorder who took lithium had increased hippocampal and amygdala volumes compared to those not taking the medication. Lithium treatment also restored cerebral volume reductions associated with longer illness duration.
The European Menopause and Andropause Society publishes two important position statements covering common management problems in post-reproductive health, including hormone therapy options for Cardiovascular disease and Osteoporosis. The statements provide summary recommendations for clinicians to manage menopause-related symptoms.
Researchers found that mice with chronic morphine exposure showed decreasing physical dependence during abstinence, but developed depressive-like symptoms. Treatment with antidepressant fluoxetine prevented these symptoms.
A new study sheds light on the complex process of recovery from aphasia after a stroke, finding that inter-hemispheric coordination plays a crucial role. The research suggests that the involvement of both hemispheres in language functions is not as binary as previously thought.
A new study published in Cortex found that the orbitofrontal cortex plays a central role in an event monitoring system, which allows us to adapt to unexpected events. The brain's response to anticipated and unexpected outcomes is influenced by the potential harm of the outcome.
Researchers have found that cognitive training can improve working memory and reduce addiction by teaching individuals to think ahead. The study, published in Biological Psychiatry, used an approach borrowed from rehabilitation of stroke or traumatic brain injury patients.
The American Society for Radiation Oncology's new journal, Practical Radiation Oncology (PRO), has published its inaugural issue. PRO will provide a forum for radiation oncologists to share information on current practices and advancements in the field. The journal aims to improve the quality of radiation oncology practice through disc...
A recent study found that approximately one-third of adolescents with any mental disorder received services for their illness, while only half of those with severely impairing mental disorders had ever received mental health treatment. The study highlights the urgent need to address barriers to recognizing and treating mental health co...
This special issue of Biological Psychiatry highlights the benefits and challenges of postmortem research in studying psychosis, schizophrenia, and other psychiatric disorders. Advances in science and technology have expanded the scope of postmortem work, allowing for more detailed studies of brain structure and function.
Research suggests that stimulating alpha-7 nicotinic receptors could enhance cortical function and improve symptoms of schizophrenia. Two studies found that low doses of AZD0328 and DMXB-A produced significant improvements in spatial working memory tasks, suggesting a potential therapeutic approach for cognitive impairments.
A study published in Biological Psychiatry found that people with schizophrenia have abnormalities in inhibitory neurons within the cortex and increases in neurons in white matter below the cortex. The researchers suggest that inhibitory neurons may be 'stuck' at a stage of development due to genetic and environmental factors.
A study published in Cortex found that the first elements of semantic memory to deteriorate are distinguishing characteristics of a concept, such as a zebra's stripes. This blurs related concepts, leading to temporary improvements in recognizing related words in early Alzheimer's disease.
The Elsevier Foundation has awarded grants to institutions in Africa and Asia for projects focusing on telemedicine, infrastructure-building, and the preservation of primary source content. The grants aim to improve access to health information and support global health development.
Research suggests that MDMA produces empathogenic effects, increasing feelings of friendliness, playfulness, and loving feelings in individuals. However, it also reduces the ability to recognize facial expressions of fear, potentially leading to increased social risk-taking.
A VA study reveals that childhood maltreatment and other high magnitude stressors have a stronger association with psychiatric symptoms than military sexual experiences. The research suggests that addressing these stressors could lead to interventions to reduce psychiatric symptoms.
Two new studies reveal distinct types of reading and writing disorders, including attentional dyslexia, which causes letter migrations between words. Italian dyslexic children's spelling impairments suggest knowledge of vocabulary is crucial in spelling, contradicting previous assumptions.
Research found that sleep deprivation eliminates fear-associated memories through both fear recognition and physiological fear reactions. This suggests a possible therapy for individuals with PTSD or other anxiety disorders.
A study found that Medicaid-funded ADHD treatment in primary care clinics was often infrequent and ineffective, with many children receiving inadequate follow-up visits and medication management. In contrast, specialty mental health clinics provided more comprehensive care, but still faced challenges in improving continuity of care.
A new study finds that smoking is associated with reduced cortical thickness in the left medial orbitofrontal cortex, negatively correlating with cigarette consumption. Heavier smoking was linked to more pronounced thinning of cortical tissue, potentially increasing the risk for addictions and cognitive decline.
The William T. Pecora Award recognizes Prof. Marvin Bauer's outstanding contributions to remote sensing education, science, and applications. The award highlights his research in agriculture, forestry, and lake water quality monitoring.
Research found that a high-fat cholesterol diet in rats caused memory impairment, inflammation, and brain damage similar to Alzheimer's disease. The study suggests a possible link between chronic high cholesterol levels and the pathology of this disease.
Registered dietitians can effectively manage Type 1 and Type 2 diabetes by following the American Dietetic Association's nutrition practice guidelines. Key recommendations include consistency in carbohydrate intake, adjusting insulin doses, and incorporating cardioprotective nutrition interventions.
Researchers found compelling evidence for the birth of a stellar mass black hole in the type IIL supernova SN 1979C. The study proposes that the late time glow of the supernova is consistent with a black hole accreting material from either a fallback disk or a binary companion.
A family history of Alzheimer's disease significantly increases the risk for developing the disorder, with a new study suggesting that which parent has the disease is crucial. Researchers found altered levels of amyloid and oxidative stress proteins in adult children of mothers with Alzheimer's, increasing their risk.
Elsevier will donate 10% of its revenue to MSF for all subscriptions to MD Consult, purchased between Nov. 15 and Dec. 31, 2010. This campaign aims to provide medical assistance and support to people around the world affected by war, natural disasters, and other crises.
Research reveals widespread internal exposure of humans to cosmetic UV filters, found in 85% of human milk samples, comparable to PCBs. The presence of UV filters is correlated with the use of cosmetic products containing these filters.
The Canadian Journal of Cardiology will benefit from the partnership, enhancing the dissemination of medical knowledge relevant to cardiovascular disease. The journal under the editorial leadership of Stanley Nattel, MD, FRSC, FRCPC, FACC, FHRS, aims to publish peer-reviewed material pertinent to specialists and general practitioners.
A recent study found that total health care expenditures for children with autism spectrum disorders (ASDs) per 10,000 covered lives grew by 32.8% from $1,270,435 in 2000 to $1,686,938 in 2003. The treated prevalence of autism increased by 32.2% during the same period.
The Journal of Infection and Public Health (JIPH) has been selected for inclusion in the US National Library of Medicine's MEDLINE database. This recognition increases the journal's visibility and impact on international readership, making it easier for authors to publish their work and be cited more widely.
The new guidelines, published by Elsevier, provide detailed advice for healthcare professionals on how to treat cardiac arrest and continue treatment after the heart has been restarted. In many cases, therapeutic hypothermia is recommended to increase survival rates.
A new study reveals that men are up to twice as likely to develop alcoholism as women, with increased dopamine release in the brain contributing to this difference. The study found that men had greater dopamine release than women after consuming an alcoholic drink, which may contribute to the initial reinforcing properties of alcohol a...
Confirmed speakers from top biopharma companies and regulatory experts will discuss dealmaking, commercial strategy, outsourcing, and regulatory risks in Asia. The summit will also explore China healthcare reform, U.S. FDA actions in China and India, and opportunities for pre-competitive collaboration.
A national study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that approximately one in five children in the US will experience severe mental disorders, which disrupt daily life. Anxiety disorders were the most common condition, followed by behavior disorders and mood disorders.
The Journal of Molecular Diagnostics is published on behalf of the Association for Molecular Pathology (AMP) and the American Society for Investigative Pathology (ASIP). The journal publishes high-quality original papers on scientific advances in molecular diagnostics.