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Elsevier


PANDAS don't like stress

A new study found that stress can aggravate the impact of prior streptococcal infection on symptoms of Tourette syndrome and obsessive-compulsive disorder. The researchers identified a link between psychosocial stress and worsening tic and obsessive-compulsive symptom severity in children with Tourette syndrome and OCD.

SourceElsevier·JournalBiological Psychiatry·DateApr 9, 2010

Synergy between behavioral and pharmacologic interventions for ADHD

A study published in Biological Psychiatry compared the effects of medication, motivation, and a combination of both on response inhibition in children with ADHD. The results showed that stimulant medication tends to normalize brain function, while motivational incentives also play a role in improving performance.

SourceElsevier·JournalBiological Psychiatry·DateApr 6, 2010

Older adults remember the good times

Older adults remember past experiences positively due to strong brain connections between emotion and memory regions. In contrast, young adults lack these connections, making it harder to recall positive events.

SourceElsevier·JournalCortex·DateMar 24, 2010

Childhood adversity may promote cellular aging

Research finds childhood maltreatment can lead to shorter telomeres, a marker of biological aging, and increased risk of age-related diseases. The study suggests early developmental experiences may have profound effects on biology, influencing cellular mechanisms that accelerate aging.

SourceElsevier·JournalBiological Psychiatry·DateMar 16, 2010

25th anniversary of anti-AIDS drugs

The 25th anniversary of antiretroviral drug development is celebrated with a milestone Special Issue in Elsevier's Antiviral Research journal, featuring review articles from key players in the field. HIV-1 has gone from being an 'inherently untreatable' agent to one eminently susceptible to approved therapies.

SourceElsevier·JournalAntiviral Research·DateMar 3, 2010

Don't make that face at me!

A new study published in Biological Psychiatry suggests that the lateral prefrontal cortex (LPFC) is a brain region that helps people control their emotional reactions to negative facial expressions from their romantic partners. The LPFC activity was found to predict self-regulation after an interpersonal conflict in daily life.

SourceElsevier·JournalBiological Psychiatry·DateMar 2, 2010

A new generation of rapid-acting antidepressants?

Researchers found that scopolamine, a muscarinic cholinergic receptor antagonist, reduced symptoms of depression within three days. The study also showed that participants experienced full symptom remission by the end of the treatment period.

SourceElsevier·JournalBiological Psychiatry·DateMar 1, 2010

Rwandan genocide survivors provide new insights into resilience and PTSD

A study of Rwandan genocide survivors found that genetic variations in the catechol-O-methyltransferase (COMT) gene affect PTSD risk. Survivors with certain genetic markers showed increased resilience to stress-related problems, while others were more vulnerable. The findings provide new insights into the complex relationship between t...

SourceElsevier·JournalBiological Psychiatry·DateFeb 25, 2010

New Business Horizons special issue on US health care

This Special Issue of Business Horizons addresses critical issues in US healthcare, including rising costs, quality, and accessibility. The issue features research on topics such as consumerism, information technology, lean-manufacturing concepts, and patient-centered medical homes to improve healthcare delivery and management.

SourceElsevier·JournalBusiness Horizons·DateFeb 24, 2010

A face is more than the sum of its parts

Acquired prosopagnosia sufferers process faces as a whole, rather than in parts, according to new study findings. This 'locally restricted, serial processing style' is inefficient for certain types of information, hindering real-life face recognition.

SourceElsevier·JournalCortex·DateFeb 10, 2010

Predicting effectiveness of flu vaccination campaigns

A new study predicts the impact and cost-effectiveness of different vaccination options for pandemic influenza, revealing that prioritizing high-risk individuals is likely very cost-effective. The model was applied to the 2009 H1N1 outbreak and accurately predicted when the epidemic would peak and who should be vaccinated.

SourceElsevier·JournalVaccine·DateFeb 9, 2010

1 billion are hungry -- can we reduce hunger now and by 2050?

A Special Issue of Agricultural Water Management highlights the need for investments in agriculture to improve food security and address global hunger. Investments in irrigation and rainfed agriculture are crucial to increase food production and household incomes in developing countries.

SourceElsevier·JournalAgricultural Water Management·DateFeb 1, 2010

Losing sleep, losing brain?

A study published in Biological Psychiatry found that chronic insomnia is associated with smaller volumes in brain regions involved in memory formation and pleasantness evaluation. Insomnia patients have lower grey matter density in these regions, which may impact their ability to recognize optimal comfort for falling asleep.

SourceElsevier·JournalBiological Psychiatry·DateJan 27, 2010

New biological models of homeopathy published in special issues

A two-part special issue published in the journal Homeopathy explores experiments on homeopathic treatments using biological models, including whole animals and plants, cell cultures, and enzymes. The study found that seven different biological models of high dilution response yielded consistently positive results.

SourceElsevier·JournalHomeopathy·DateJan 18, 2010

Color my numbers

A study published in Cortex found that synaesthetes can exhibit automatic color experiences when presented with numbers or patterns, regardless of their conscious awareness. The research suggests that learning may contribute to the development of these associations.

SourceElsevier·JournalCortex·DateDec 17, 2009

How do we understand written language?

A study published in Cortex identifies the left fusiform gyrus as necessary for normal understanding of written text and correct word spelling. The findings suggest that this brain area is specialized and required for orthographic processing.

SourceElsevier·JournalCortex·DateDec 16, 2009

Will copper keep us safe from the superbugs?

Researchers found that copper surfaces had significantly fewer live bacteria than conventional surfaces, with one study showing a 71% reduction. Copper-based disinfectants also showed effective antimicrobial properties, continuing to kill germs for the rest of the day.

SourceElsevier·JournalJournal of Hospital Infection·DateDec 1, 2009

New safety concern related to antipsychotic treatment

Researchers found that antipsychotic medications increase levels of inflammatory markers, contributing to the risk of diabetes, hypertension, and heart disease in patients. The study highlights the need for monitoring cardiovascular risk markers in antipsychotic-treated patients.

SourceElsevier·JournalBiological Psychiatry·DateDec 1, 2009

Milestone biodefense publication by Elsevier journal Vaccine

The Elsevier journal Vaccine has released a supplement dedicated to vaccines for biodefense, showcasing significant advancements in vaccine development against diverse human and veterinary pathogens. The publication acknowledges the shift from traditional military focus to protecting both civilian and military populations.

SourceElsevier·JournalVaccine·DateNov 19, 2009

Common plastics chemicals linked to ADHD symptoms

A study published in Biological Psychiatry found a significant positive association between phthalate exposure and ADHD symptoms in school-aged children. The researchers measured urine phthalate concentrations and evaluated symptoms of attention-deficit/hyperactivity disorder (ADHD) using teacher-reported symptoms and computerized tests.

SourceElsevier·JournalBiological Psychiatry·DateNov 19, 2009

Are teenagers wired differently than adults?

Researchers studied amygdala development, finding that neural pathways bypassing cortex are more plastic in juvenile than adult mice. This suggests that teenagers' emotions are less precise and more irrational due to subcortical drive.

SourceElsevier·JournalBiological Psychiatry·DateNov 17, 2009

Elsevier sponsors 2009 Semantic Web Challenge

The 2009 Semantic Web Challenge recognized four outstanding applications that demonstrated practical applicability to real-world issues. The winners were awarded cash prizes sponsored by Elsevier, promoting the dissemination of knowledge from academia to society.

Getting on 'the GABA receptor shuttle' to treat anxiety disorders

A new study published in Biological Psychiatry examined the role of GABA receptors in anxiety disorders, revealing that inserting GABA receptors into neurons in the amygdala increases inhibition and prevents fear extinction. This discovery provides evidence for molecular mechanisms behind cognitive and behavioral therapies.

SourceElsevier·JournalBiological Psychiatry·DateOct 22, 2009

Maternal smoking may increase newborns' discomfort

A new study suggests that maternal smoking during pregnancy may increase newborns' distress levels, potentially related to reduced monoamine oxidase A (MAO-A) activity. This reduction in MAO-A activity can lead to dysregulation of brain neurotransmission, creating a potential vulnerability to behavioral disorders later in life.

SourceElsevier·JournalBiological Psychiatry·DateOct 21, 2009

Treating depression in pregnancy

A recent study published in General Hospital Psychiatry found that depressive symptoms and antidepressant treatment are associated with fetal growth changes, shorter gestations, and neonatal irritability. The research highlights the need for pregnant women to receive adequate care and support to mitigate these risks.

SourceElsevier·JournalGeneral Hospital Psychiatry·DateSep 21, 2009

Ketamine reduces suicidality in depressed patients

In a preliminary study, intravenous ketamine was found to acutely reduce suicidal thoughts in treatment-resistant depression patients. The reduction in suicidality was maintained when patients received repeated doses over two weeks, suggesting potential as an attractive treatment option for high-risk suicidal patients.

SourceElsevier·JournalBiological Psychiatry·DateSep 10, 2009

Hormone levels contribute to stress resilience

A recent study published in Biological Psychiatry found that hormone levels play a crucial role in stress resilience among military combat divers. Soldiers with higher dehydroepiandrosterone (DHEA) levels performed better during stressful underwater navigation exercises.

SourceElsevier·JournalBiological Psychiatry·DateAug 5, 2009

Looking at language

A study published in Cortex found that Parkinson's patients struggle with grammatically complex sentences due to degeneration of dopamine-secreting neurons. Eye-tracking data revealed slower response times when processing relative clauses, but not at the end of sentences.

SourceElsevier·JournalCortex·DateAug 4, 2009