The International Society of Andrology, European Association of Urology, and other scientific organizations have formulated new recommendations on late-onset hypogonadism (LOH) treatment. These guidelines emphasize the importance of addressing symptoms such as erectile dysfunction and low testosterone levels in aging men.
The NHS must make substantial changes in administration and management structure to effectively manage top-up payments and keep accurate records of patient care. The cost of drugs is not the only cost to the NHS, as patients who purchase drugs and stay in the hospital reduce resources for all remaining patients.
The supplement addresses complex issues surrounding second trimester abortion, including methods, values, and public policy. In-depth country-based research is needed to bring out facts and support second trimester abortion as a legitimate form of women's health care.
A study published in Clinical Immunology describes a new method to induce regulatory T cells, which show great potential for treating autoimmune diseases and improving transplant outcomes. The method uses an inexpensive and simple high-yield approach to generate large amounts of these immune suppressive cells.
The new journal, PM&R, emphasizes principles of injury, function, and rehabilitation, covering topics such as musculoskeletal disorders, neurologic conditions, and rehabilitation of impairments. The journal aims to advance education and impact the specialty through timely delivery of clinically relevant research and review information.
A study published in Clinical Oncology found that funding decisions for cancer patients with exceptional circumstances are influenced by their location rather than their health needs. This has led to a postcode lottery, where some patients receive funding while others do not, despite similar circumstances.
The paper 'CEVITATM: the valuation and reporting of strategic capabilities' by Janek Ratnatunga, Norman Gray, and Kashi R. Balachandran has been awarded the Management Accounting Section (MAS) Greatest Potential Impact on Practice Award for its potential to bridge the gap between academic research and professional management accounting...
A recent study published in European Urology found a significant relationship between prostate inflammation and lower urinary tract symptoms (LUTS) in men. The study, which analyzed data from the REDUCE trial, revealed that chronic inflammation was associated with higher IPSS scores and a greater degree of LUTS.
A growing body of research suggests that consuming foods rich in grape polyphenols can help reduce the risk of heart disease. Grape polyphenols have been shown to slow or prevent cell damage caused by oxidation and decrease the oxidation of low-density lipoprotein cholesterol.
Elsevier announces a new partnership with Society of Powder Technology Japan (SPTJ) to publish Advanced Powder Technology, a bimonthly journal covering powder engineering and technology. The internationalization of the journal will expand its reach and contribute high-quality content to ScienceDirect.
Research suggests that cerebral inflammation and microglia activation contribute to schizophrenia development. Anti-inflammatory agents targeting activated microglia may provide a new treatment option for the condition.
Research suggests that birth hypoxia may contribute to the development of schizophrenia by reducing brain-derived neurotrophic factor (BDNF) levels. The study found a significant decrease in BDNF among individuals who later developed schizophrenia, highlighting the importance of maternal health during pregnancy.
Researchers found that deleting the gene for glutamate transporter EAAT1 leads to increased responses to NMDA receptor antagonist MK-801, resulting in schizophrenia-like features in mice. The study suggests a promising new class of glutamate-targeting antipsychotic treatments may help correct these abnormalities.
A study found that the genome in people who have committed suicide as a result of major depression was being chemically modified, with nearly ten times the rate of methylation compared to control groups. This modification involved genes regulating behavior and neurotransmitter receptors.
A new genetic association study found associations between six mouse genes and specific human anxiety disorders, including social phobia, generalized anxiety disorder, and panic disorder. The study suggests that these genes may play a role in predisposing individuals to developing an anxiety disorder.
A new study finds that developing depression after a heart attack substantially increases the risk of cardiac-related morbidity and mortality. This increased risk is significant, even when controlling for traditional cardiac risk factors.
A new animal model study suggests that high-dose corticosterone, a cortisol-related substance, can prevent negative consequences of stress exposure in PTSD. Low-dose corticosterone potentiated these responses, indicating a dose-dependent relationship between corticosterone levels and vulnerability/resilience.
The journal has been included in the Social Science Citation Index due to its exceptional awareness of current issues affecting the field of management accounting. Management Accounting Research features original research, case studies, and empirical work on topics such as management change, risk management, and corporate governance.
Recent studies suggest a possible link between long-term cell phone use and increased risk of brain tumors, prompting a call for collaborative research initiatives. Scientists emphasize the need for definitive evidence to determine the risks associated with electromagnetic field exposure from cell phones.
A new prostate cancer gene test using a urine sample has shown promising results in detecting the disease at an early stage. The test, PCA3, is highly specific to PCa and may allow patients to avoid unnecessary biopsies.
The Elsevier journal Vaccine released a comprehensive supplement dedicated to influenza vaccines, supported by the International Federation of Pharmaceutical Manufacturers and Associations. Key findings include discussions on pandemic influenza vaccine challenges and the importance of robust global surveillance systems.
A new study suggests that people with Alzheimer's disease may have lower blood pressure because of cognitive decline. Failing memory causes forgetfulness, which can lead to a decrease in stress-related high blood pressure.
Research studies reveal strong associations between exposure to Bisphenol A, phthalates and flame retardants and adverse health effects on humans and laboratory animals. Exposure during fetal life or prior to weaning can disrupt brain development, reproductive systems, and behavior.
A recent study reveals that seabirds are a significant source of nitrogen in remote coastal ecosystems, contributing to eutrophication and acidification. The research found varying emissions between seabird species, with bare ground nesters producing more ammonia than burrow nesters.
The Asian Journal of Psychiatry aims to bridge a knowledge gap in psychiatric research and development across Asia, focusing on regional mental health issues. The first issue includes reports on psychosocial responses to disasters, highlighting the need for evidence-based literature on psychiatric disorders in the Asian continent.
Hallucinations are associated with changes in brain connections and localized activity, highlighting the need for a broader perspective on the condition. The study reveals increased activity in visual brain regions and alterations in connection strength, shedding light on the neural basis of hallucinations.
A new method allows for the detection of multiple immune parameters from individual human cells, which may aid in diagnosing diseases such as type 1 diabetes. This breakthrough enables researchers to study rare blood cells and their role in autoimmune diseases, leading to potential novel biomarkers for therapy monitoring.
Researchers found that losing sleep for part of one night activates cellular pathways producing tissue-damaging inflammation, linked to increased risk of cardiovascular disease and autoimmune disorders. Good sleep habits may ease this risk.
A new study published in Biological Psychiatry found that adding N-acetyl cysteine to usual treatment improved depressive symptoms in individuals with bipolar disorder. The study suggests a potential new treatment option for psychiatric disorders, particularly those involving brain glutathione metabolism.
Researchers found that chronic stress alters the genetic immune response by changing the pattern of gene expression in monocytes, a type of white blood cell involved in the body's immune response. This altered response can lead to increased inflammation and contribute to the risk for illnesses like depression, heart disease, and diabetes.
A new study suggests that blocking the corticotrophin releasing factor-1 (CRF1) receptor and the vasopressin-1B (V1B) receptor may retain their efficacy in treating depression, even when neurogenesis is disrupted. The researchers found that restoration of the stress axis may be key to how these new antidepressant approaches work.
A study published in the Journal of AAPOS found that pirenzepine gel can slow the rate of progressive myopia in children, with an average increase of 0.58 diopters over two years compared to 0.99 diopters in the placebo group. The treatment was generally safe and effective, with only mild side effects reported.
SourceElsevier·JournalJournal of American Association for Pediatric Ophthalmology and Strabismus·DateAug 26, 2008
A study published in European Urology found that vardenafil, a PDE5 inhibitor, is more efficacious when used on-demand in men with erectile dysfunction following bilateral nerve-sparing radical prostatectomy. On-demand use of vardenafil was associated with significantly greater erectile function and sexual intercourse completion rates ...
A new study published in European Urology found that patients who underwent robot-assisted laparoscopic radical prostatectomy experienced higher levels of dissatisfaction and regret, particularly African-American patients. Longer follow-up periods were also associated with increased regret.
A recent study identified a bluetongue virus strain that originated in sub-Saharan Africa, rather than Europe. The discovery was made through multi-centre sequence analysis of the full genome of the virus strain and its comparison to other BTV strains.
The Journal of Allergy and Clinical Immunology has published a special issue focusing on AIDS and HIV research, featuring reviews on vaccine development, B-cell abnormalities, and viral reservoirs. Key findings also include an increased rate of asthma in HIV-infected children treated with HAART.
Researchers found that physical surroundings where alcohol cues are experienced can greatly influence the ability of those cues to trigger relapse. The study suggests that presenting cues repeatedly in multiple distinct contexts without alcohol can diminish their triggering effect.
Eating CLA-enriched cookies increases levels of conjugated linoleic acid in breast milk, a potentially healthful fatty acid. The study found significant higher levels of CLA in breast milk from women who ate CLA-enriched cookies compared to those who ate regular cookies.
Researchers found that oxytocin increases the encoding of positive social memories, allowing individuals to better recall happy faces. This breakthrough has potential implications for treating psychiatric disorders related to social isolation.
The special issue highlights promising therapeutic targets and techniques to measure the effects of disease-modifying therapies on cerebral amyloid β levels. Clinical trials are underway, and several promising drugs are headed towards clinical trials, offering cautious optimism for new AD therapeutics.
A recent study published in Biological Psychiatry found four chromosomal regions linked to schizophrenia and bipolar disorder risk factors, suggesting that these disorders may represent different genetic subtypes. The discovery highlights the complexity of psychiatric diagnoses and provides new insights into potential treatment targets.
A study published in Biological Psychiatry found that individuals with schizophrenia and bipolar disorder share a core set of genes involved in nervous system development and cell death. This common genetic signature may provide a window into discovering new brain mechanisms and effective treatments for these debilitating conditions.
The journal will play a key role in the Asia-Pacific Region's entomological research community, publishing original research papers and review articles. Elsevier has agreed to publish the journal on behalf of three societies, aiming to promote leading entomological research from Asia and worldwide.
A meta-analysis of D-cycloserine and fear extinction found that the medication improves the effectiveness of behavioral therapy for anxiety disorders. Tolerance may develop to its effects, suggesting it should be used before therapy sessions to enhance brain responsiveness.
The European Urology journal has released its new impact factor of 5.634, highlighting the journal's outstanding quality and international profile. This achievement is directly related to the success of the European Association of Urology (EAU), which represents over 16,000 urologists across Europe and worldwide.
A new study has replicated the association between genetic variation in the FKBP5 gene and treatment response to antidepressants, suggesting a potential link to childhood maltreatment. The findings support earlier research implicating the same gene and provide encouragement for personalized medicine approaches to depression treatment.
The NIMH CNTRICS Initiative aims to improve schizophrenia treatment by defining cognitive processes and neural circuits. Cognitive neuroscience insights are being translated into better treatments for impaired cognition in schizophrenia.
A new experimental technique has yielded improved vision in patients with retinal degeneration, with seven of ten patients showing significant visual gains. The procedure involves transplanting fetal retinal cells along with their attached retinal pigment epithelium to replace damaged photoreceptor cells.
A study found that state policies requiring comprehensive diagnostic criteria and specific services are associated with positive treatment outcomes. Most programs performed diagnostic assessment, group and individual therapy, but had lower rates of family counseling.
A study published in the Journal of Substance Abuse Treatment reveals that 14% of hospital admissions are due to alcohol/drug abuse and addiction disorders. The study found that these disorders were associated with significantly higher hospital costs, particularly for opioid abuse, which increased by 482%.